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Mexican Guidelines for the Diagnosis and Treatment of Chronic Myeloid leukaemia

Journal of Cancer Therapy 2013年第3期4卷 747-764页

作者： Eduardo Cervera Federico Godínez Rosa Sosa Ramón Rivas Carlos Best Juan Hernández Adrián Morales Hugo Zurita Ivette Carrasco Jorge Cruz álvaro Aguayo José Espinoza Juan labardini luis Valero Judith Cruz Diana Arcos Diego limón omar lópez-navarro Daniela Gordillo-Bastidas Myrna Candelaria Francisco Torres Juan Kassack Oscar de Jesús Pérez Ramírez Jorge Aquino Guillermo Díaz Mariela Cardiel Margarita Rodríguez Patricia Montoya Juan Contreras María Chávez Sandra Chávez David Gómez Olga Cantú Jorge Duque luis Pita Eduardo lobato Julio lópez Antonio lópez Pedro González Jorge Cortés Haematology and Oncology Department National Institute of Medical and Nutrition Sciences “Dr. Salvador Zubirán” Mexico City Mexico Haematology Deparment from Hospital Juárez Mexico City Mexico Haematology Department Blood Bank and Unit of Aphaeresis General Hospital of Culiacán Health Ministry Culiacán Mexico Haematology Department Bone Marrow Transplant and Blood Bank from Hospital Regional de Alta Especialidad “Dr. Juan Graham Casassus” Villahermosa Mexico Haematology Department Cancerology National Institute (INCan) Mexico City Mexico Haematology Department Cancerology National Institute (INCan) Mexico City Mexico 2Internal Medicine Haematology Hospital ISSSTECALI Tijuana Mexico Haematology Department Centenario Hospital Miguel Hidalgo Health Ministry Aguascalientes Mexico Haematology Department General Hospital of Sonora State Sonora Mexico Haematology Department Hospital Universitario UANL Monterrey Mexico Haematology Haematology Service Hospital General Regional SSG León Mexico Haematology Head of Haematology Service School of Medicine Autonomous University of San Luis Potosí San Luis Potosí Mexico Haematology Hospital “Aranda de la Parra” León Mexico Haematology Hospital General de Especialidades Campeche Mexico Haematology Hospital General de México Mexico City Mexico Haematology Hospital General de Occidente SSA Guadalajara Mexico Haematology Hospital Regional de Alta Especialidad de Oaxaca Oaxaca Mexico Haematology Mérida Clinic Yucatán Mexico Haematology Oncology Unit SSEP Puebla Mexico Hospital Betania Puebla Mexico Hospital of the Poblano Child Puebla Mexico Internal Medicine Haematology Hospital ISSSTECALI Tijuana Mexico leukaemias Clinic at ISSEMyM Toluca Mexico leukemia Department MD Anderson Cancer Center Houston Mexico los Mochis General Hospital Sinaloa Mexico Renaissance Clinic Morelia Mexico State Council for AIDS Prevention and Control Chihuahua Mexico Universidad Autónoma de Yucatán Mérida Mexico

Background: This document includes recommendations and guidelines issued by a group of Mexican researchers and specialists gathered in the First National Colloquium for the Diagnosis and Management of Chronic Myeloid leukaemia (CMl) by initiative of Instituto Nacional de Cancerología and with the support of the leukaemia Department of the MD Anderson Cancer Center. Mexico lacks of updated information taken from its own reality on the diagnosis and treatment of CMl and other haematological disorders;besides, there are no national guidelines. Aim: To publish a consensus document with guidelines for the management of CMl adjusted to the national environment and overall characteristics. Method: The participants answered a DElPHI questionnaire about the overall aspects of the disease, aiming to target controversial topics, discuss them in the colloquium, and to agree on the best ones. After those meetings, a final document was drawn up. Results: The group presents recommendations for definition, diagnosis, prognosis, monitoring, and treatment of CMl in Mexico. Conclusions: Having consensus guidelines for the clinical management of CMl in our country will enable the consensual practice of Mexican specialists regarding the clinical approach to CMl, as well as optimize the resources which allow the rational planning of the medical care strategies.

关键词： Chronic Myeloid leukaemia Management Guidelines Diagnosis Treatment.

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Modelling the impacts of cover crop management strategies on the water use,carbon exchange and yield of olive orchards

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Journal of Forestry Research 2023年第1期34卷 283-295页

作者： Alvaro lópez-Bernal omar García-Tejera luca Testi Francisco J.Villalobos Departamento de Agronomía Universidad de CórdobaCampus de RabanalesEdifi cio C414071 CórdobaSpain Departamento de Ingeniería Agraria Y del Medio Natural Universidad de La LagunaCarretera General de Geneto 238200 San Cristóbal de La LagunaSpain Instituto de Agricultura Sostenible(IAS) Consejo Superior de Investigaciones Científi cas(CSIC)Av.Menéndez Pidal S/N14080 CórdobaSpain

Cover crops have long been proposed as an alternative soil management for minimizing erosion rates in olive stands while providing additional ecosystem ***,the trade-off between these benefits and the competition for water with the trees makes the definition of optimal management practices a challenging task in semiarid *** work presents an improved version of OliveCan,a process-based simulation model of olive orchards that now can simulate the main impacts of cover crops on the water and carbon balances of olive *** simple in its formulation,the new model components were developed to deal with different cover crop management *** are presented for simulation runs of a traditional olive orchard in the conditions of southern Spain,evaluating the effects of different widths for the strip occupied by the cover crop(Fcc)and two contrasting mowing *** revealed that high Fccresulted in lower olive yields,but only when mowing was applied at the end of *** this regard,late mowing and high Fccwas associated with lower soil water content from spring to summer,coinciding with olive flowering and the earlier stages of fruit *** also negatively correlated with surface runoff irrespective of the mowing *** the other hand,net ecosystem productivity(NEP)was substantially affected by both Fccand mowing *** simulations under future climate scenarios comparing the same management alternatives are also presented,showing substantial yield reductions by the end of the century and minor or negligible changes in NEP and seasonal runoff.

关键词： Carbon exchange Cover crops Crop modelling Evapotranspiration Olea europaea l

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Mexican Guidelines for the Diagnosis and Treatment of Chronic Myeloid leukaemia

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Journal of Cancer Therapy 2013年第3期

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Assessing above-ground biomass-functional diversity relationships in temperate forests in northern Mexico

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Forest Ecosystems 2021年第1期8卷 95-108页

作者： Benedicto Vargas-larreta Jorge omar lópez-Martínez Edgar J.González JoséJavier Corral-Rivas Francisco Javier Hernández Tecnológico Nacional de México/Instituto Tecnológico de El Salto 34942 El SaltoDurangoMexico Cátedras CONACYT1582Av.Insurgentes SurCiudad de MéxicoMexico El Colegio de la Frontera Sur 77014ChetumalQuintana RooMexico Departamento de Ecología y Recursos Naturales Facultad de CienciasUniversidad Nacional Autónoma de MéxicoCiudad de MéxicoMexico Facultad de Ciencias Forestales Universidad Juárez del Estado de DurangoRío Papaloapan y Blvd.Durango s/nCol.Valle del Sur34120 DurangoMexico

Background:Studies on the relationship between biodiversity and ecosystem productivity have suggested that species richness and functional diversity are the main drivers of ecosystem *** patterns on this relationship have been found,including positive,unimodal,negative,and neutral trends,keeping the issue *** this study,taxonomic diversity and functional diversity as drivers of above-ground biomass(AGB)were compared,and the mechanisms that influence biomass production were investigated by testing the complementarity and the mass-ratio ***:Using data from 414 permanent sample plots,covering 23%of temperate forest in the Sierra Madre Oriental(México),we estimated the above-gound biomass(AGB),taxonomic and functional diversity indices,as well as community weighted mean values(CWM)for three functional traits(maximum height,leaf size and wood density)for trees≥7.5 cm DBH,in managed and unmanaged *** compare taxonomic diversity differences between managed and unmanaged stands we carried out a rarefaction ***,we evaluated the relationship between AGB and taxonomic and functional diversity metrics,as well as CWM traits throught spatial autoregressive ***:We found a hump-shaped relationship between AGB and species richness in managed and unmanaged *** of maximum height was the most important predictor of AGB in both stands,which suggested that the mechanism underlaying the AGB-diversity relationship is the dominance of some highly productive species,supporting the mass-ratio ***-ground biomass was significantly correlated with three of the five functional diversity metrics,CWM maximum height and species *** results show the importance of taking into account spatial autocorrelation in the construction of predictive models to avoid spurious patterns in the AGBdiversity ***:Species richness,maximum height,functional richness,functional dispersion and Rao

关键词： Taxonomic diversity Functional diversity Complementarity hypothesis Mass-ratio hypothesis

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Optical imaging of post-embryonic zebrafish using multi orientation raster scan optoacoustic mesoscopy

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light(Science & Applications) 2016年第1期5卷 336-341页

作者： Murad omar Johannes Rebling Kai Wicker Tobias Schmitt-Manderbach Mathias Schwarz Jérôme Gateau Hérnan lópez-Schier Timo Mappes Vasilis Ntziachristos Chair for Biological Imaging Technische Universität MünchenMünchen D-81675Germany Institute for Biological and Medical Imaging Helmholtz Zentrum MünchenNeuherberg D-85764Germany Carl Zeiss AG Corporate Research and TechnologyJena D-07745Germany ESPCI Paris PSL Research UniversityCNRSINSERMInstitut LangevinParis F-75005France Research Unit Sensory Biology and Organogenesis Helmholtz Zentrum MünchenNeuherberg D-85764Germany Carl Zeiss Vision International GmbH Technology&InnovationAalen D-73430Germany

Whole-body optical imaging of post-embryonic stage model organisms is a challenging and long sought-after *** requires a combination of high-resolution performance and high-penetration ***(photoacoustic)mesoscopy holds great promise,as it penetrates deeper than optical and optoacoustic microscopy while providing high-spatial ***,optoacoustic mesoscopic techniques only offer partial visibility of oriented structures,such as blood vessels,due to a limited angular detection aperture or the use of ultrasound frequencies that yield insufficient *** introduce 3601 multi orientation(multi-projection)raster scan optoacoustic mesoscopy(MORSOM)based on detecting an ultra-wide frequency bandwidth(up to 160 MHz)and weighted deconvolution to synthetically enlarge the angular *** report unprecedented isotropic inplane resolution at the 9–17μm range and improved signal to noise ratio in phantoms and opaque 21-day-old *** find that MORSOM performance defines a new operational specification for optoacoustic mesoscopy of adult organisms,with possible applications in the developmental biology of adulthood and aging.

关键词： deconvolution development mesoscopy multiview optoacoustics photoacoustics

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Application of solvent evaporation technique for pure drug crystal spheres preparation

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Particuology 2022年第8期20卷 79-89页

作者： omar Mady Department of Pharmaceutical Technology Faculty of Pharmacy Tanta UniversityEgypt

An innovative application ofthe solventevaporation technique was *** tech nique is a technique for drug encapsulation and nanosphere *** widely used technique is also facing the problem of low actual drug entrapment percent,which is not economic from the industrial *** goal of this work is trying to use the advantage of this technique concerning the product sphericity and the ability to control particle size,to prepare a drug as pure crystals *** is selected as a model *** spheres are formed by using Polyvinyl pyrrolidone(PVP)or Polyethylene glycol(PEG)as an anti-aggregating agent but not formed on using tween or *** size and actual drug content depend on the concentrations the anti-aggregating agent *** of the drug crystal spheres are porous with empty sphere internal structure on using PvP but spongy and rough on using *** drug has its identity chemical form in the drug crystal *** scan of spheres prepared on using PEG showed a characteristic ether *** showed melting endothermic peak of PEG,but X-ray showed minor change in the drug crystal *** release profiles from crystal spheres prepared with the same anti-aggregating agent are close to each *** drug release profiles from drug crystal spheres prepared by using PEG are more controlled than that prepared by using *** drug release mechanism is *** was concluded that,the same technique could be suggested for preparation ofother biomedical material in pure crystals spheres with controlled particle *** properties may encourage to prepare very small particles with spherical shape for inhalation or injection as an innovative particle technology application for the widely used technique.

关键词： Solvent evaporation technique Drug crystal spheres Ibuprofen Polyvinyl pyrrolidone Polyethylene glycol

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Monolayer MoS_(2)/n-Si Heterostructure Schottky Solar Cell

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Journal of Renewable Materials 2022年第7期10卷 1979-1988页

作者： omar Salih omar The University of Duhok College of ScienceDepartment of PhysicsDuhokKurdistan RegionIraq

Monolayer MoS_(2)has a promising optoelectronics property,with a bandgap in the visible range;the material is a potential candidate for solar cell *** this work,we grew MoS_(2)monolayers using a low-pressure chemical vapor deposition *** produce uniform wafer-scale MoS_(2)monolayer films,precursors molybdenum dioxide(MoO_(2))and sulfur(S)are *** force microscopy was used to quantify the thickness of the monolayers,and the result was validated by Raman *** electron microscopy(TEM)was used to confirm the crystalline quality of the monolayers,and photoluminescence spectroscopy was used to evaluate their optical *** were able to create a Schottky solar cell with a MoS_(2)monolayer up to 1 cm2 area by transferring monolayer film to n-type *** MoS_(2)/n-Si Schottky solar cell demonstrated photovoltaic characteristics with a short circuit current density of 14.8 mA cm^(-2)and an open-circuit voltage of 0.32 V under 100 mW cm^(-2)*** fill factor and energy conversion efficiency were 53%and 2.46%,respectively,with the highest external quantum efficiency at 530 nm being 44%.

关键词： MoS_(2)monolayers chemical vapor deposition Schottky solar cell

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Effect of malathion on the male reproductive organs of earthworms, Eisenia foetida

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Asian Journal of Andrology 2005年第1期7卷 97-101,页

作者： omar Espinoza-navarro Eduardo Bustos-Obregon Department of Biology and Health Faculty of Sciences University of Tarapacd Arica Chile laboratory of Biology of Reproduction ICBM Faculty of Medicine University of Chile Santiago Chile

Aim: To observe the cytotoxic effect of the organophosphate insecticide malathion in the reproductive tissues of the earthworms, Eisenia foetida. Methods: Worms were nourished in soil treated with malathion at single sub-lethal doses of 0, 80, 150, 300 and 600 mg-kg^(-1) soil. (lD_(50) = 880 mg kg^(-1) soil) and evaluated on days 1, 5, 15 and 30 after exposure. The body weights were recorded and male reproductive organs evaluated. Results: Malathion-treated animals showed a significant reduction in body weight in a dose-dependent manner. Malathion treatment modified the disposition of spermatozoa in the basal epithelium of the spermatheca. The Br-deoxyuridine test showed a significant rise in cells in phase S on days 5 and 15. Also, a higher percentage of spermatogonia with fragmented DNA were observed by means of the TdT-mediated dUTP nick-end labeling (TUNEl) technique in the spermatheca of treated animals. Conclusion: Treatment with malathion decreased the body weight and the spermatic viability in spermatheca, altering the cell proliferation and modifying the DNA structure of spermatogonia.

关键词： Eiseniafoetida malathion reproductive organs apoptosis

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Point Charge between Two Grounded and Conducting Planes Forming a 60°Angle and for Yukawa’s Potential and Coulomb’s Potential

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Journal of Electromagnetic Analysis and Applications 2021年第4期13卷 57-66页

作者： Miguel Angel lópez-Mariño omar Olmos lópez José Manuel Pardo Regueiro Tecnologico de Monterrey Escuela de Ingeniería y Ciencias Chihuahua México Tecnologico de Monterrey Escuela de Ingeniería y Ciencias Monterrey México Tecnologico de Monterrey Escuela de Ingeniería y Ciencias Torreón México

For a point charge between two grounded conductor planes forming a 60° angle, the potential and electric field generated by point charge for Yukawa’s potential (e-μr/r) and Coulomb’s potential (1/r) are modeled and simulated. The expression for the potential that generalizes the cases discussed in lópez-Mariño, M. and Trujillo Caballero, J. (2017) Point Charges and Conducting Planes for Yukawa’s Potential and Coulomb’s Potential. Journal of Electromagnetic Analysis and Applications, 9, 135-146. lank">https://***/10.4236/jemaa.2017.910012 is presented. Graphs for the potential and electric field for both cases are showed using Maple, that of Coulomb and that of Yukawa for different values of μ . The purpose of this work is to offer students a practical guide for problem analysis of electrostatics using Maple’s capabilities as a computational tool.

关键词： Yukawa’s Potential Coulomb’s Potential Method of Images

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VISCOMETRIC INVESTIGATIONS OF POlYVINYlPYRROlIDONE IN MIXED SOlVENTS AND WITH VARYING TEMPERATURE

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Chinese Journal of Polymer Science 2005年第4期23卷 367-371页

作者： omar Melad omar Abu-Tiem Rajai Baraka Chemistry Department

The viscosity behavior of polyvinylpyrrolidone(PVP)has been determined at 25℃ in mixed solvents comprising water/dimethylformamide(DMF)and water/methanol(MeOH).Analysis of the data has considered the PVP as being both host and guest polymer in *** intrinsic viscosity of PVP in DMF is higher than in water and in MeOH,but also increases in a mixed solvent with high water content because of the effect of polymer-solvent *** was also found that the intrinsic viscosity of PVP at finite concentration,[η_(pvp)]_c decreases with an increase in the concentration of PVP in *** viscosity behavior of PVP in a mixed solvent is affected by the concentration-dependent intermolecular excluded volume effect,which can be quantitatively expressed by the parameter,b_Y,which reflects the shrinkage of PVP chain coils,resulting in a decrease of[η_(pvp)]_*** effect of temperature on the viscosity behavior of PVP in MeOH shows that the interaction parameter increases up to a maximum value,and then decreases after a certain temperature.

关键词： Polyvinylpyrrolidone Intermolecular excluded volume effect Intrinsic viscosity

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