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Pedunculated colonic lipoma prolapsing through the anus

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World Journal of Clinical Cases 2015年第5期3卷 457-461页

作者： omar M ghanem Julia Slater Puneet Singh Richard F Heitmiller Joseph D Di Rocco Department of Surgery Medstar Union Memorial Hospital Baltimore MD 21218 United States Saba University School of Medicine Devens MA 01434 United States

Colorectal lipomas are the second most common benign tumors of the colon. These masses are typically incidental findings with over 94% being asymptomatic. Symptoms-classically abdominal pain, bleeding per rectum and alterations in bowel habits-may arise when lipomas become larger than 2 cm in size. Colonic lipomas are most often noted incidentally by colonoscopy. They may also be identified by abdominal imaging such as computed tomography or magnetic resonance imaging. We report a case of a sixty-one years old male who presented to our emergency room with a 6.7 cm × 6.3 cm soft tissue mucosal mass protruding transanally. The patient was stable with a benign abdominal examination. The mass was initially thought to be a rectal prolapse; however, a limited digital rectal exam was able to identify this as distinct from the anal canal. Since the mass was irreducible, it was elected to be resected under anesthesia. At surgery, manipulation of the mass identified that the lesion was pedunculated with a long and thickened stalk. A laparoscopic linear cutting stapler was used to resect the mass at its stalk. Pathology showed a polypoid submucosal lipoma of the colon with overlying ulceration and necrosis. We report this case to highlight this rare but possible presentation of colonic lipomas; an incarcerated, trans-anal mass with features suggesting rectal prolapse. Trans-anal resection is simple and effective treatment.

关键词： Colorectal lipoma Rectal prolapse Transanal resection

Turnkey algorithmic approach for the evaluation of gastroesophageal reflux disease after bariatric surgery

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Gastroenterology Report 2023年第1期11卷 123-130页

作者： omar M.ghanem Rabih Ghazi Farah Abdul Razzak Fateh Bazerbachi Karthik Ravi Leena Khaitan Shanu N.Kothari Barham K.Abu Dayyeh Department of Surgery Mayo ClinicRochesterMNUSA Department of Medicine Mayo ClinicRochesterMNUSA CentraCare Interventional Endoscopy ProgramSt Cloud HospitalSt CloudMNUSA Department of Surgery CaseWestern Reserve UniversityClevelandOHUSA Department of Surgery Prisma HealthGreenvilleSCUSA

Bariatric surgeries are often complicated by de-novo gastroesophageal reflux disease(GERD)or worsening of pre-existing *** growing rates of obesity and bariatric surgeries worldwide are paralleled by an increase in the number of patients requiring post-surgical GERD ***,there is currently no standardized approach for the assessment of GERD in these *** this review,we delineate the relationship between GERD and the most common bariatric surgeries:sleeve gastrectomy(SG)and Roux-en-Y gastric bypass(RYGB),with a focus on pathophysiology,objective assessment,and underlying anatomical and motility *** suggest a stepwise algorithm to help diagnose GERD after SG and RYGB,determine the underlying cause,and guide the management and treatment.

关键词： RYGB sleeve gastrectomy bariatric surgery gastroesophageal reflux disease GERD

Allolobophora caliginosa coelomic fluid ameliorates gentamicin-induced hepatorenal toxicity in rats

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Asian Pacific Journal of Tropical Biomedicine 2020年第9期10卷 411-416页

作者： Saad Bin Dajem Sara Bayoumi Ali omar ghanem Abdelrady Nouraldin Mahmoud Salahaldin Ahmed Muhammed Soliman Yasmin Mohamed Kamal Ammar Yasser Abdelazim Aya Fadi Mohamed Kareem Morsy Ayman Saber Mohamed Sohair Ramadan Fahmy Department of Biology College of ScienceKing Khalid UniversityAbhaSaudi Arabia Department of Zoology Faculty of ScienceCairo UniversityCairoEgypt

Objective:To explore the efficacy of earthworm’s coelomic fluid against gentamicin-induced hepatic and renal toxicity in ***:The animals were divided randomly into three groups(n=6 per group):control,gentamicin,and Allolobophora caliginosa coelomic fluid-treated *** was established after injection of gentamicin daily for 8 days at a dose of 100 mg/*** aminotransferase,alanine aminotransferase,alkaline phosphatase,total proteins,albumin,creatinine,urea,uric acid,malondialdehyde,glutathione,catalase and histopathology of tissues were investigated in the ***:Allolobophora caliginosa coelomic fluid significantly decreased urea,creatinine,uric acid,alanine aminotransferase,aspartate aminotransferase,alkaline phosphatase,and malondialdehyde levels while significantly increasing levels of total proteins,albumin,glutathione and *** histopathological investigation showed partial restoration of renal and hepatic ***:This study shows the potency of Allolobophora caliginosa coelomic fluid in improving the biochemical and histopathological changes induced by gentamicin in the liver and kidney of the rats.

关键词： Allolobophora caliginosa Coelomic fluid Gentamicin Hepatorenal toxicity Earthworm

Solitary rectal ulcer syndrome presenting as polypoid mass lesions in a young girl

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World Journal of Gastrointestinal Oncology 2010年第8期2卷 332-334页

作者： omar I Saadah Maram S Al-Hubayshi Ahmad T ghanem Department of Pediatrics King Abdul-Aziz University Department of Anatomical Pathology King Abdul-Aziz University

Solitary rectal ulcer syndrome (SRUS) is a rare condition in children. We report a case of SRUS in an 8-year old Saudi girl who presented with recurrent rectal bleeding,intermittent mucosal prolapse,and passage of mucus per rectum. Colonoscopy revealed multiple polypoid mass lesions with histopathological features of SRUS. The polypoid variant of SRUS is very rare in children and may be confused with rectal malignant or inflammatory conditions.

关键词： Polypoid Rectal prolapse Rectal bleeding Child Solitary rectal ulcer syndrome Saudi Arabia