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A systematic literature review on the effectiveness of eurythmy therapy

Journal of integrative Medicine 2015年第4期13卷 217-230页

作者： Désirée Lotzke Peter Heusser Arndt Büssing Quality of Life Spirituality and Coping Institute of Integrative Medicine University of Witten/Herdecke Theory of Medicine Integrative and Anthroposophic Medicine Institute of Integrative MedicineUniversity of Witten/Herdecke

BACKGROUND：eurythmy therapy is a movement therapy of anthroposophic medicine that can have effects on a person’s physical body,spirit,and ***：The aim of this publication was to update and summarize the relevant literature on the effectiveness of eurythmy in a therapeutic context since *** STRATeGY：Different databases like Pub Med,MeDPiLOT,Research Gate,The Cochrane Library,DiMDi,Arthe and also the journal databases Der Merkurstab and the european Journal of integrative Medicine were searched for prospective and retrospective clinical trials in German or english *** CRiTeRiA：There were no limitations for indication,considered outcome or age of *** eXTRACTiON AND ANALYSiS：Studies were evaluated with regard to their description of the assembly process and treatment,adequate reporting of follow-ups,and equality of comparison groups in controlled ***：eleven studies met the inclusion *** included two single-arm,non-controlled pilot studies,two publications on the same non-randomized controlled trial and one case study;six further studies referred to a prospective cohort study,the Anthroposophic Medicine Outcome *** of these studies described positives treatment effects with varying effect *** studies were heterogynous according to the indications,age groups,study design and measured *** methodological quality of the studies varied *** were no clear improvements since 2008,when the recommendations were published in the fi rst ***：eurythmy seems to be a benefi cial add-on in a therapeutic context that can improve the health conditions of affected *** methodologically sound studies are needed to substantiate this positive impression.

关键词： eurythmy therapy mind-body and relaxation techniques anthroposophy review

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起搏器相关上肢静脉血栓1例及文献回顾

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安徽医药 2024年第5期28卷 981-986,I0006页

作者：许蔡艳钱金娥严佳栋李柯蓓苏州大学附属张家港医院药学部江苏张家港215600 苏州大学附属张家港医院心内科江苏张家港215600

目的临床药师通过参与1例起搏器相关上肢深静脉血栓的抗凝治疗,为缺乏大型随机临床研究的栓塞疾病提供合理用药参考。方法1例78岁的老年男性病人起搏器植入术后24 d左上肢出现静脉血栓,临床药师通过查阅文献,结合案例报道、循证依据及... 详细信息

目的临床药师通过参与1例起搏器相关上肢深静脉血栓的抗凝治疗,为缺乏大型随机临床研究的栓塞疾病提供合理用药参考。方法1例78岁的老年男性病人起搏器植入术后24 d左上肢出现静脉血栓,临床药师通过查阅文献,结合案例报道、循证依据及病人血栓及出血风险评估,与医师共同为病人制定个体化抗凝方案,并提供药学服务。结果医师采纳临床药师抗凝治疗建议,采用利伐沙班抗凝,1个月后血栓消失,总疗程5个月,期间未有血栓和出血事件。结论临床药师可协助医师优化缺乏循证依据病种的治疗方案,提高药物治疗的安全性及有效性,为临床药学服务提供新思路。

关键词：上肢深静脉血栓利伐沙班药学服务临床药师抗栓起搏器

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Understanding Contaminant Veins in Squeeze Casting and Semi-solid Metalworking Processes

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特种铸造及有色合金 2003年第Z1期23卷 230-234,238页

作者： edward J. Vinarcik, P.e. engineer Voctorie Co.8218 Medicine Bow Run Fort WayreIdiana 46825 U.S A

When commercializing the semi-solid metalworking processes, component producers looked to conventional die-casting to identify potential defects and control component quality. Several defects were expected including cold shuts, cold flows, flash, drags, warping, and gas entrapment, just to name a few. efforts were taken to avoid these defects. A new defect type, contaminant veins, has surfaced unique to semi-solid metalworking. Although, semi-solid metalworking has proven to be successful, component producers have been reluctant to report defects for fear of giving this emerging processes a bad reputation. Nonetheless, this defect must be understood to avoid future problems.

关键词： Contaminant Veins Squeeze Casting Semi-solid Casting

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时代新人的内涵演进、典型特征与涵育策略

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山东高等教育 2024年第4期12卷 74-79,92页

作者：周裕钧卢俊汝周湘鄂崔晶晶合肥经济学院安徽合肥230031 皖江工学院马克思主义学院安徽马鞍山243071 湖南财经经济学院湖南长沙410205 西北政法大学陕西西安710199

党的十九大报告首次提出了时代新人的概念,并将其作为社会主义核心价值观培养的重要目标。时代新人的内涵随历史发展不断演进,经历了“共产主义新人”“四有新人”和“担当民族复兴重任的时代新人”三个阶段的变化。当前的时代新人具备... 详细信息

党的十九大报告首次提出了时代新人的概念,并将其作为社会主义核心价值观培养的重要目标。时代新人的内涵随历史发展不断演进,经历了“共产主义新人”“四有新人”和“担当民族复兴重任的时代新人”三个阶段的变化。当前的时代新人具备信仰坚定、心怀天下、勤勉实干、开拓创新等典型特征。新的时代背景下,应坚持以习近平文化思想武装时代新人、以知行合一理念磨砺时代新人、以作为思政课载体培育时代新人。

关键词：时代新人内涵演进典型特征涵育策略

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Sensitivities of Numerical Model Forecasts of extreme Cyclone events

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Advances in Atmospheric Sciences 1991年第1期8卷 51-66页

作者： A. C. Yih J. e. Walsh Department of Atmospheric Sciences University of Illinois Urbana IL 61801Department of Atmospheric Sciences University of Illinois Urbana IL 61801

A global forecast model is used to examine various sensitivities of numerical predictions of three extreme winter storms that occurred near the eastern continental margin of North America: the Ohio Valley blizzard of January 1978, the New england blizzard of February 1978, and the Mid-Atlantic cyclone of February 1979. While medium-resolution simulations capture much of the intensification, the forecasts of the precise timing and intensity levels suffer from various degrees of error. The coastal cyclones show a 5-10 hPa dependence on the western North Atlantic sea surface temperature, which is varied within a range (± 2.5℃) compatible with interannual fluctuations. The associated vertical velocities and precipitation rates show proportionately stronger dependences on the ocean temperature perturbations. The Ohio Valley blizzard, which intensified along a track 700-800 km from the coast, shows little sensitivity to ocean temperature. The effect of a shift of - 10?latitude in the position of the snow boundary is negligible in each case. The forecasts depend strongly on the model resolution, and the coarse-resolution forecasts are consistently inferior to the medium-resolution forecasts. Studies of the corresponding sensitivities of extreme cyclonic events over eastern Asia are encouraged in order to identify characteristics that are common to numerical forecasts for the two regions.

关键词： Sensitivities of Numerical Model Forecasts of extreme Cyclone events SST

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Co-,Fe-,Ni-doped and co-doped rutile GeO_(2):insights from ab-initio calculations

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Communications in Theoretical Physics 2022年第4期74卷 113-126页

作者： R essajai e Salmani M Bghour A Labrag F Goumrhar M Fahoume H ez-Zahraouy Materials and Subatomic Physics Laboratory Faculty of SciencesIbn Tofail UniversityKenitraMorocco Group of Semiconductors and environmental Sensor Technologies-energy Research Center Faculty of ScienceMohammed V UniversityB.P.1014RabatMorocco Laboratory of Condensed Matter and interdisciplinary Sciences Department of PhysicsFaculty of SciencesMohammed V UniversityP.O.Box 1014RabatMorocco equipe des Matériaux Supraconducteursàhaute température critique Department of PhysicsIbn Zohr UniversityFaculty of SciencesBP:8106AgadirMorocco Faculty of Applied Sciences Route Nationale N°10 citéAzrouAit MelloulIbn Zohr UniversityAit MelloulIbn Zohr UniversityMorocco Higher School of education and Training of el Jadida(eSeF) Chouaib Doukkali UniversityEl Jadida 24000Morocco Laboratory of Physics of High energy Modeling&Simulations(LPHE-MS)Faculty of SciencesMohammed V University of RabatIbn BatoutaB.P.1014 RabatMorocco Laboratoire des Sciences de l’ingénieur pour l’energie Ecole Nationale des Sciences Appliquées d’El Jadida(ENSA-J)BP 1166EL Jadida Plateau24002Morocco

Rutile germanium oxide(rutile GeO_(2)),a semiconductor,can act as a half-metallic compound and is a promising material for spintronic and optoelectronic *** were performed using the Korringa–Kohn–Rostoker(KKR)approach and the coherent potential approximation(CPA),which were further combined with two approximations,the local density approximation(LDA)and the self-interaction corrected LDA approximation(LDA-SiC),to study the electronic structure of bulk rutile GeO_(2) doped and co-doped with three transition-metal impurities:Fe,Co,and *** doping value was set to 10%,while the co-doping level was set to 5%for each *** main findings of this work are:(1)a direct ultrawide bandgap of4.80 eV is observed and the rutile GeO_(2) exhibits an N-type semiconducting property.(2)Doped and co-doped GeO_(2) acquire a magnetic behavior and exhibit half-metallicity.(3)The mechanism responsible for these properties is also studied.(4)The critical temperature can reach 334 K when GeO_(2) is doped with Fe,while it rises to 398 K when it is co-doped with Fe and Co.(5)The spin polarization can be improved by *** can be inferred that rutile GeO_(2) doped or codoped with(Co,Fe)transition metals can be considered to be potential candidates for spintronic and optoelectronic applications.

关键词： LDA approximation spintronic Curie temperature spin polarization LDA-SiC approximation rutile germanium oxide

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Primary mucosa-associated lymphoid tissue lymphoma.of the liver: A report of two cases and review of the literature

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World Journal of Hepatology 2017年第3期9卷 155-160页

作者： ifeyinwa e Obiorah Lynt Johnson Metin Ozdemirli Department of Pathology Medstar Georgetown University Hospital Department of Surgery Medstar Georgetown University Hospital

Mucosa-associated lymphoid tissue(MALT) lymphoma.of the liver is a very rare condition and thus the diag-nosis may be challeng-ing-. The clinical presentation is usually variable, rang-ing- from minimal clinical symptoms to severe end stag-e liver disease. in this paper, we describe the clinicopatholog-ic finding-s in two cases of primary hepatic MALT lymphoma. One case is an 80-year-old female with no underlying- chronic liver disease and the second case is a 30-year-old female with autoimmune hepatitis complicated by MALT lymphoma. in both specimens, there was diffuse infiltration of atypical B-lymphocytes that were positive for CD20 and CD79 a, but neg-ative for CD5, CD43 and CD10. There were occasional lymphoepithelial lesions involving- the hepatocytes or bile ducts. Polymerase chain reaction analysis showed monoclonal immunog-lobulin heavy chain g-ene rearrang-ement in both cases. The first case was treated with surg-ery but developed pulmonary recurrence a year after complete resection but went into remission following- treatment with rituximab. A second recurrence occurred in the rig-ht parotid g-land 7 years later, which was treated with idelalisib. The second case was effectively treated with rituximab. To our knowledg-e, the second case is the first reported case linked to autoimmune hepatitis.

关键词： extranodal Mucosa-associated lymphoid tissue Lymphoepithelial Lymphoma Polymerase chain reaction

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肥胖型多囊卵巢综合征患者不孕的危险因素分析

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中国现代医学杂志 2024年第13期34卷 20-27页

作者：汪艳虹张春娥洪金平石清上饶市妇幼保健院生殖科江西上饶334000 上饶市妇幼保健院宫颈盆底科江西上饶334000

目的探讨肥胖型多囊卵巢综合征(PCOS)患者不孕的危险因素,以提供更有效的治疗策略和预防措施。方法选取2020年3月—2023年3月在上饶市妇幼保健院就诊的126例PCOS伴不孕患者作为PCOS组,并选取同期在该院体检的健康志愿者102例作为对照组... 详细信息

目的探讨肥胖型多囊卵巢综合征(PCOS)患者不孕的危险因素,以提供更有效的治疗策略和预防措施。方法选取2020年3月—2023年3月在上饶市妇幼保健院就诊的126例PCOS伴不孕患者作为PCOS组,并选取同期在该院体检的健康志愿者102例作为对照组。通过调查问卷的形式收集两组一般临床资料,采用生育问题量表(FPi)评估不孕相关的压力水平,匹兹堡睡眠质量指数(PSQi)量表评估睡眠障碍,酶联免疫吸附试验(eLiSA)检测血抑制素B(iNHB)、抗苗勒氏管激素(AMH)水平,电化学发光法检测促卵泡激素(FSH)、黄体生成激素(LH)、孕酮、雌二醇(e_(2))、睾酮(T)、性激素结合球蛋白(SHBG),彩色多普勒超声仪计算两侧卵泡数量。采用多因素一般Logistic回归分析影响肥胖型PCOS不孕的危险因素。结果两组受试者一般资料比较,差异无统计学意义(P>0.05);两组受试者的体质量指数(BMi)、睡眠障碍、生育压力、两侧卵泡数量、iNHB、AMH、FSH、LH、孕酮、e_(2)、T、SHBG水平比较,差异均有统计学意义(Pistic回归分析结果显示,BMi[OR=1.272(95%Ci:1.153,1.402)]、睡眠障碍[OR=3.191(95%Ci:2.045,4.978)]、生育压力[OR=1.021(95%Ci:1.014,1.027)]、左侧卵巢泡数[OR=1.092(95%Ci:1.006,1.186)]、右侧卵巢泡数[OR=1.160(95%Ci:1.074,1.252)]、iNHB[OR=1.007(95%Ci:1.001,1.013)]、AMH[OR=1.138(95%Ci:1.032,1.256)]、LH[OR=1.190(95%Ci:1.115,1.271)]、T[OR=1.304(95%Ci:1.173,1.450)]是肥胖型PCOS患者不孕的独立危险因素(Pi:0.670,0.867)]、孕酮[OR=0.624(95%Ci:0.463,0.841)]、e_(2)[OR=0.994(95%Ci:0.988,1.000)]、SHBG[OR=0.977(95%Ci:0.956,0.999)]是肥胖型PCOS患者不孕的保护因素(Pi:0.951,0.993)、敏感性为96.8%(95%Ci:0.913,0.991),特异性为94.3%(95%Ci:0.813,0.971),拟合曲线显示回归模型拟合效果良好。结论肥胖型PCOS患者不孕的危险因素是BMi较高、睡眠障碍、生育压力大、两侧卵巢卵泡数增多、iNHB、AMH、FSH、LH,而孕酮、e_(2)、SHBG为保护因素。

关键词：多囊卵巢综合征胰岛素抵抗肥胖内分泌代谢列线图

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Cancer stem cell plasticity and tumor hierarchy

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World Journal of Stem Cells 2015年第1期7卷 27-36页

作者： Marina Carla Cabrera Robert e Hollingsworth elaine M Hurt Medimmune LLC Department of Oncology ResearchGaithersburg MD 20878 United States

The origins of the complex process of intratumoral heterogeneity have been highly debated and different cellular mechanisms have been hypothesized to account for the diversity within a tumor. The clonal evolution and cancer stem cell(CSC) models have been proposed as drivers of this heterogeneity. However, the concept of cancer stem cell plasticity and bidirectional conversion between stem and non-stem cells has added additional complexity to these highly studied paradigms and may help explain the tumor heterogeneity observed in solid tumors. The process of cancer stem cell plasticity in which cancer cel s harbor the dynamic ability of shifting from a non-CSC state to a CSC state and vice versa may be modulated by specific microenvironmental signals and cellular interactions arising in the tumor niche. in addition to promoting CSC plasticity, these interactions may contribute to the cellular transformation of tumor cells and affect response to chemotherapeutic and radiation treatments by providing CSCs protection from these agents. Herein, we review the literature in support of this dynamic CSC state, discuss the effectors of plasticity, and examine their role in the development and treatment of cancer.

关键词： Cancer stem cells Stem cell Plasticity Tumor hierarchy Microenvironment immune-mediatedtherapies epithelial-to-mesenchymal transition

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建立梯度提升机模型预测RiCU机械通气并发呼吸机相关性肺炎患者的短期预后

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广西医学 2024年第1期46卷 78-83页

作者：黄小芬夏良娥赵世元黄敏敏崇左市人民医院呼吸内科广西崇左市532200 崇左市人民医院科研科广西崇左市532200 崇左市人民医院检验科广西崇左市532200

目的构建梯度提升机(GBM)模型预测呼吸重症监护病房(RiCU)机械通气患者并发呼吸机相关性肺炎(VAP)的短期预后情况。方法回顾性分析RiCU收治的350例机械通气并发VAP患者的临床资料,根据随访结局将患者分为死亡组(n=110)和生存组(n=240),... 详细信息

目的构建梯度提升机(GBM)模型预测呼吸重症监护病房(RiCU)机械通气患者并发呼吸机相关性肺炎(VAP)的短期预后情况。方法回顾性分析RiCU收治的350例机械通气并发VAP患者的临床资料,根据随访结局将患者分为死亡组(n=110)和生存组(n=240),筛选影响其预后的危险因素。按8∶2比例将患者随机分为训练集280例和验证集70例,采用R语言4.2.1软件构建GBM预测RiCU机械通气并发VAP患者的短期预后模型并评价模型的预测效能。结果年龄、机械通气时间、C反应蛋白(CRP)水平、血清降钙素原水平、急性生理学与慢性健康状况评分系统Ⅱ(APACHeⅡ)评分及序贯器官衰竭评估(SOFA)评分是RiCU机械通气并发VAP患者预后的影响因素(Pi:0.894,0.958),敏感度为85.4%、特异度为86.2%,在验证集中的AUC为0.880(95%Ci:0.779,0.980),敏感度为85.7%、特异度为86.4%;校准曲线显示,GBM模型的预测概率与实际发生率基本一致;决策曲线分析显示,训练集和验证集的阈概率分别在0.10~0.98、0.10~0.80。结论基于年龄、机械通气时间、CRP水平、血清降钙素原水平、APACHeⅡ评分及SOFA评分构建的GBM模型对RiCU机械通气并发VAP患者的短期预后情况有较好的预测价值。

关键词：呼吸机相关性肺炎机械通气呼吸重症监护病房梯度提升机模型危险因素预后

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