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Evaluation of intratesticular chlorhexidine gluconate for chemical contraception in dogs

Asian pacific Journal of Reproduction 2022年第5期11卷 231-235页

作者： Aeknath Virendra om prakash Shrivastava Satya Nidhi Shukla Manish Kumar Shukla Nitin Kumar Bajaj Afroza Khanam Firdous Ahmad Khan Department of Animal Reproduction Gynecology and ObstetricsNanaji Deshmukh Veterinary Science UniversityJabalpur482001Madhya PradeshIndia Department of Animal Reproduction Gynecology and ObstetricsSardar Vallabhbhai Patel UniversityMeerut250110Uttar PradeshIndia Department of Large Animal Medicine and Surgery School of Veterinary MedicineSt.George’s UniversityTrue BlueGrenadaWest Indies

Objective:To investigate the contraceptive effect of intratesticular injection of chlorhexidine gluconate in dogs and compare it with that of zinc gluconate neutralized with ***:Twenty-four sexually mature male mongrel dogs were randomly divided by replicate into four groups(n=6 per group).GroupⅡreceived intra-testicular injection of 2 mL zinc gluconate(10 mg/mL)neutralized with ***Ⅱreceived intratesticular injection of 2 mL chlorhexidine gluconate(5%w/v).GroupⅢreceived intratesticular injection of 2 mL chlorhexidine gluconate(4%w/v).GroupⅣdid not receive any treatment and served as the control *** morphometry was conducted on day 0,7,15 and 30 after *** was collected and evaluated on day 0 and *** were analyzed using repeated measures analysis of ***:There was no difference in the mean values of various parameters between dogs treated with zinc gluconate and those treated with chlorhexidine gluconate at any of the time *** dogs treated with zinc gluconate or chlorhexidine gluconate,there was a significant increase in the testicular morphometric parameters on day 7 followed by a significant reduction thereafter(day 15 and 30).In contrast,there was no change in any of the parameters in the control untreated dogs during the course of the *** to the pre-treatment values,the mean scrotal circumference and the mean paired testicular volume and testicular weight on day 30 were significantly lower in the treated *** samples collected on day 30 from treated dogs were found to be azoospermic,whereas no change in semen quality was observed in the control untreated ***:Intratesticular injection of chlorhexidine gluconate(5%w/v and 4%w/v)is equally as effective as zinc gluconate neutralized with arginine for chemical contraception in dogs.

关键词： Canine Contraception Zinc gluconate Chlorhexidine gluconate Morphometry

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Numerical and Dimensional Analysis for Prediction of Line Heating Residual Deformations

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Journal of Marine Science and Application 2010年第1期9卷 14-21页

作者： Pankaj Biswas Nisith Ranjan Mandal om prakash Sha Department of Ocean Engineering and Naval Architecture

Line heating process is a very complex phenomenon as a variety of factors affects the amount of residual deformations. Numerical thermal and mechanical analysis of line heating for prediction of residual deformation is time consuming. In the present work dimensional analysis has been presented to obtain a new relationship between input parameters and resulting residual deformations during line heating process. The temperature distribution and residual deformations for 6 mm, 8 mm, 10 mm and 12 mm thick steel plates were numerically estimated and compared with experimental and published results. Extensive data generated through a validated FE model were used to find co-relationship between the input parameters and the resulting residual deformation by multiple regression analysis. The results obtained from the deformation equations developed in this work compared well with those of the FE analysis with a drop in the computation time in the order of 100 (computational time required for FE analysis is around 7 200 second to 9 000 seconds and where the time required for getting the residual deformation by developed equations is only 60 to 90 seconds).

关键词： dimensional analysis 3-D finite element analysis elasto-plastic analysis residual deformations multiple regression analysis oxy-acetylene gas flame

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Effects of Thermal Diffusion and Chemical Reaction on MHD Flow of Dusty Visco-Elastic (Walter’s Liquid Model-B) Fluid

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Journal of Electromagnetic Analysis and Applications 2010年第10期2卷 581-587页

作者： om prakash Devendra Kumar Y. K. Dwivedi Department of Mathematics Ganjdundwara P.G. College Ganjdundwara Kashiram Nagar (U.P.)-India Department of Mathematics Hindustan College of Science and technology Farah Mathura (U.P.)-India

The present note consists, the effects of thermal diffusion and chemical reaction on MHD flow of dusty viscous incom-pressible, electrically conducting fluid between two vertical heated, porous, parallel plates with heat source/sink. The plate temperature is raised linearly with time and concentration level near the plate to Cw. The variable temperature and uniform mass diffusion taking into account the chemical reaction of first order. The series solution method is used to solve the mathematical equations. Effects of various parameters like chemical reaction (K), thermal diffusion (ST) and magnetic field (M) etc. on velocity profile, skin friction, concentration profile and temperature field are displayed graphically and discussed numerically for different physical parameters. The analysis developed here for thermal diffusion, bears good agreement with real life problems.

关键词： MHD Flow Thermal Diffusion (Soret Effect) Heat Source/Sink Skin Friction

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Role of angiotensin converting enzyme and angiotensinogen gene polymorphisms in angiotensin converting enzyme inhibitor-mediated antiproteinuric action in type 2 diabetic nephropathy patients

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World Journal of Diabetes 2017年第3期8卷 112-119页

作者： Neerja Aggarwal Pawan Kumar Kare Parul Varshney om prakash Kalra Sri Venkata Madhu Basu Dev Banerjee Anil Yadav Alpana Raizada Ashok Kumar Tripathi Department of Medicine University College of Medical Sciences (University of Delhi) and Guru Teg Bahadur Hospital Department of Biochemistry University College of Medical Sciences (University of Delhi) and Guru Teg Bahadur Hospital Pt. B. D. Sharma University of Health Sciences

AIM To investigate the role of genetic variants of angiotensin converting enzyme(ACE) and angiotensinogen(AGT) genes in the antiproteinuric efficacy of ACE inhibitor therapy in diabetic nephropathy(DN) *** In the present study, 270 type 2 diabetes mellitus patients with nephropathy were enrolled and treated with ACE inhibitor(ramipril) and followed at 6 mo for renal function and albumin excretion by estimating serum creatinine, end stage renal disease, and albumin/creatinine ratio(ACR) in urine. Genotyping of ACE I/D and AGT M235 T polymorphisms were performed by using primer specific polymerase chain reaction(PCR) and PCR-RFLP techniques, respectively. RESULTS Forty-eight percent of DN patients(responders) benefited with respect to proteinuria from ACE inhibitor therapy at 6 mo follow-up. A significant reduction in ACR was observed after 6 mo treatment with ACE inhibitor irrespective of whether DN patients were micro-albuminuric(≥ 30 and < 300 mg/g creatinine) or macro-albuminuric(≥ 300 mg/g creatinine) at the time of enrollment. However, macro-albuminuric patients(55%) showed better response to therapy. A reduction in urinary ACR was found independent of genotypes of ACE I/D and AGT M235 T polymorphisms although macro-albuminuric patients having TT genotype showed statistically insignificant increased response(72%). CONCLUSION ACE inhibitor therapy reduced urinary ACR by ≥ 30% in 50% of DN patients and the response is independent of ACE I/D and AGT M235 T polymorphisms.

关键词： Diabetic nephropathy Angiotensin converting enzyme inhibitor therapy Renin-angiotensin-aldosterone system gene polymorphisms Responder Urinary albumin/creatinine ratio Albuminuria

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Pharmacological, Ethnomedicinal, and Evidence-Based Comparative Review of Moringa oleifera Lam.(Shigru) and Its Potential Role in the Management of Malnutrition in Tribal Regions of India, Especially Chhattisgarh

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World Journal of Traditional Chinese Medicine 2022年第3期8卷 314-338页

作者： Kishor Sonewane Sharda Swaroop Chouhan Mariappan Rajan Nagendra Singh Chauhan om prakash Rout Awanish Kumar Gyanendra Singh Baghel Prashant Kumar Gupta Department of Kaumarabhritya-Balaroga Shri NPA Government Ayurveda CollegeRaipurChhattisgarhIndia Department of Natural Chemistry Madurai Kamraj UniversityMaduraiTamil NaduIndia Drug Testing Lab Avam Anushandhan Kendra Department of AYUSHChhattisgarhIndia Department of Dravya Guna Shri NPA Government Ayurveda CollegeRaipurChhattisgarhIndia Department of Biotechnology National Institute of TechnologyRaipurChhattisgarhIndia

Moringa oleifera Lam.(Shigru)(Moringaceae family) is a traditional medicine used for control of diabetes, obesity, asthma, and cardiac,liver, gastrointestinal, infective, and brain disorders, such as depression and Alzheimer's disease. In Ayurvedic literature, Shigru is among few drugs having Balya(nourishing) as well as Medohara(antiobesity) property. This review focuses on valid connections between the properties documented in ancient literature and current pharmacological knowledge of Moringa, including pharmacological actions, phytochemistry,botanical description, and how Moringa can tackle malnutrition in India, especially Chhattisgarh. All information about M. oleifera was obtained from electronic scientific databases such as PubMed, Web of Science, Scopus, ScienceDirect, Elsevier, Google Scholar, Traditional Knowledge Digital Library, and Indian Traditional Books(Ancient Ayurveda literatures, The Wealth of India, and The Ayurvedic Formulary of India), postgraduate/doctoral thesis, and googling the keyword M. oleifera. M. oleifera have anti-oxidant, antimicrobial, anti-diabetic,anti-obesity, anti-inflammatory, cardioprotective, hepatoprotective, neuroprotective, gastroprotective, wound-healing properties and it can potentially tackle malnutrition. This review describes the key information related to botanical description of M. oleifera, phytochemistry,pharmacological actions, clinical studies, toxicological studies, better utilization as food therapeutics, and ethnobotanical and evidence-based comparative review of M. oleifera. M. oleifera can effectively tackle malnutrition in India, especially Chhattisgarh. The authors emphasize the need for future in-depth ethnopharmacological lead-based research and clinical studies to expand M. oleifera pharmacological activities,clinical efficacy, and safety.

关键词： Ethnobotanical practices ethnomedicine Moringa oleifera phytochemicals pharmacological action

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LOD Cloud Mining for Prognosis Model(Case Study: Native App for Drug Recommender System)

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Advances in Internet of Things 2014年第3期4卷 20-28页

作者： Nidhi Kushwaha Raman Goyal Pramiti Goel Sidharth Singla om prakash Vyas Department of Information Technology Indian Institute of Information Technology (IIIT-A) Allahabad India

The goal of this project is to use the Semantic Web Technologies and Data Mining for disease diagnosis to assist health care professionals regarding the possible medication and drug to prescribe (Drug recommendation) according to the features of the patient. Numerous Decision Support Systems (DSS) and Expert Systems allow medical collaboration, like in the differential diagnosis specific or general. But, a medical recommendation system using both Semantic Web technologies and Data mining has not yet been developed which initiated this work. However, it should be mentioned that there are several system references about medicine or active ingredient interactions, but their final goal is not the Drug recommendation which uses above technologies. With this project we try to provide an assistant to the doctor for better recommendations. The patient will also able to use this system for explanation of drugs, food interaction and side effects of corresponding drugs.

关键词： Linked Life Drug Data Cloud Recommender System Data Mining Semantic Web

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Linking a Simulated Annealing Based Optimization Model with PHT3D Simulation Model for Chemically Reactive Transport Processes to Optimally Characterize Unknown Contaminant Sources in a Former Mine Site in Australia

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Journal of Water Resource and Protection 2017年第5期9卷 432-454页

作者： Bithin Datta Claire Petit Marine Palliser Hamed K. Esfahani om prakash Discipline of Civil Engineering College of Science and Engineering James Cook University Townsville QLD Australia CRC-CARE (Cooperative Research Centre for Remediation and Assessment of the Environment) University of Newcastle Callaghan NSW Australia Water and Environment Program Ecole Nationale Supérieure d’Ingénieurs de Limoges (ENSIL) Limoges France Department of Civil and Environmental Engineering I. I. T. Patna India

Historical mining activities often lead to continuing wide spread contaminants in both groundwater and surface water in previously operational mine site areas. The contamination may continue for many years after closing down the mining activities. The essential first step for sustainable management of groundwater and development of remediation strategies is the unknown contaminant source characterization. In a mining site, there are multiple species of contaminants involving complex geochemical processes. It is difficult to identify the potential sources and pathways incorporating the chemically reactive multiple species of contaminants making the source characterization process more challenging. To address this issue, a reactive transport simulation model PHT3D is linked to a Simulated Annealing based the optimum decision model. The numerical simulation model PHT3D is utilized for numerically simulating the reactive transport process involving multiple species in the former mine site area. The simulation results from the calibrated PHT3D model are illustrated, with and without incorporating the chemical reactions. These comparisons show the utility of using a reactive, geochemical transport process’ simulation model. Performance evaluation of the linked simulation optimization methodology is evaluated for a contamination scenario in a former mine site in Queensland, Australia. These performance evaluation results illustrate the applicability of linked simulation optimization model to identify the source characteristics while using PHT3D as a numerical reactive chemical species’ transport simulation model for the hydro-geochemically complex aquifer study area.

关键词： Groundwater Contamination Source Characterization PHT3D Linked Simulation Optimization Methodology Chemically Reactive Transport Simulation Mine Site Contamination Simulated Annealing

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Electron Monopole Duality in Quantum Hall Effect

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Journal of Electromagnetic Analysis and Applications 2011年第1期3卷 22-26页

作者： Pawan Ku. Joshi Praveen Singh Bisht om prakash Singh Negi 不详

Starting from the duality between electric and magnetic field, we have made an attempt to discuss the quantum hall effect from the consideration of magnetic monopole in view of electron monopole duality. Starting from the dual dy-namics of electric and magnetic charges, we have reformulated a consistent theory of quantum hall effect in presence of monopole. Speculating the existence of magnetic monopoles in magnetic materials (metals), we have accordingly modi-fied the parameters;like drift velocity, current density, Hamiltonian and eigen values and eigen function for harmonic oscillator;resposible to examine the quantum Hall effect in metals.

关键词： Hall Effect Monopole Quantum Mechanics

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Post-adoption behaviour of farmers towards soil and water conservation technologies of watershed management in India

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International Soil and Water Conservation Research 2015年第3期3卷 161-169页

作者： Gopal Lal Bagdi Prasanta Kumar Mishra Ravi Sankar Kurothe Swarn Lata Arya Shekhargouda Linganagouda Patil Ashok Kumar Singh Bankey Bihari om prakash Ashok Kumar Palanisamy Sundarambal ICAR–Central Sheep and Wool Research Institute Avikanagar 304501RajasthanIndia ICAR–Indian Institute of Soil and Water Conservation Dehradun 248195UttrakhandIndia

The Indian Institute of Soil and Water Conservation(IISWC)and its Research Centres have developed many successful model watershed projects in India in the past and implemented many Soil and Water Conservation(SWC)technologies for sustainable watershed *** many evaluation studies were conducted on these projects in the past,there has been no assessment of the post-adoption status of the SWC technologies over a longer *** was imperative to appraise the behaviour of the farmers with regard to the continuance or discontinuance of the technologies adopted,diffusion or infusion that took place and technological gaps that occurred in due course of time in the post watershed ***,it was realized that the postadoption behaviour of beneficiary farmers who have adopted different soil and water conservation technologies for watershed management projects should be studied in *** research study was initiated in 2012 as a core project at Vasad as the lead Centre along with IISWC headquarter Dehradun,and Centres Agra,Bellary,Chandigarh,Datia,Kota&Ooty,with the specific objectives of the study to measure the extent of post-adoption behaviour(continued-adoption,discontinuance,technological gap,diffusion and infusion)of farmers towards the adopted SWC technologies of watershed *** the present study various indices regarding continued adoption,dis-adoption(discontinuance),technological gap,diffusion,infusion regarding soil and water conservation technologies for watershed management were developed for measurement of post-adoption behaviour of *** was revealed that a little less than three-fourth(73%)of SWC technologies continued to be adopted and more than onefourth(27%)were discontinued by *** of the total continue adopted SWC technologies by farmers,a little less than onefifth(19%)of technologies continued to be adopted with a technological *** than one-fourth(28%)of SWC technologies were also diffused to other fa

关键词： Post-adoption Soil and water conservation Watershed Management

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对不同杀菌剂防治芒果炭疽病的评价

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世界热带农业信息 1989年第5期 23-24页

作者： om prakash 周世强

芒果炭疽病是由盘长孢状刺盘孢和围小丛壳引起的一种病害。在印度北方邦的特拉伊地区,芒果炭疽病特别流行。1985—1986年在拉金普尔克里的比拉(Bhiro)地区,进行了一次试验,以评价10种杀菌剂的防效。2年的试验结果表明,浓度为0.1%的多菌... 详细信息

芒果炭疽病是由盘长孢状刺盘孢和围小丛壳引起的一种病害。在印度北方邦的特拉伊地区,芒果炭疽病特别流行。1985—1986年在拉金普尔克里的比拉(Bhiro)地区,进行了一次试验,以评价10种杀菌剂的防效。2年的试验结果表明,浓度为0.1%的多菌灵,每隔15—20天施药一次,共施3—4次的放果最好。多菌灵、福镁锌、jkstein、克菌丹、王铜、Zeropal、devicopper、嗪胺灵和代森锰锌等也能较好地防治芒果炭疽病。

关键词：芒果炭疽病杀菌剂多菌灵可湿性粉剂防治代森锰锌防效克菌丹评价王铜病害

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