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Stability Assessment of Some West African Okra （Abelmoschus caillel~ Genotypes in Nigerian Genebank

Journal of Life Sciences 2011年第11期5卷 906-912页

作者： Aladele Sunday Ezekiel Omolayo Johnson Ariyo olusola babatunde kehinde2 Department of Plant Genetic Resources National Centre for Genetic Resources and Biotechnology （NACGRAB） Ibadan 200273 Nigeria Department of Plant Breeding and Seed Technology University of Agriculture A beokuta 110101 Nigeria

Stability among 50 accessions of West African okra （Abelmoschus caillei） was assessed under three diverse ecological environments at Abeokuta, Ibadan and Mokwa in Nigeria during 2005 and 2006 cropping season. The accessions were grown in a Randomized Complete Block Design with three replications; data were collected on 5-10 randomly selected plants from each plot. Only 20 accessions were subjected to stability analysis on the basis of yield across the three environments. The joint regression analysis, deviation means square were computed using Eberhart and Russell method and complemented with Francis and Kannenberg method. The regression coefficients of accessions mean yields on the environmental index resulted in regression coefficients ranging in values from 0.5549 to 1.6667. OAA/96/175-5328, NGAE-96-011 and NGAE-96-0060 were among the superior genotypes with high yield performance. The large variation in regression values indicated large differences in genotype response to different environments. It suggests that stability concept of Ebelhart and Russell could be modified to use any yield components that has strong correlation with yield for stability analysis. The two promising accessions ofA. caillei （NGAE-96-011 and NGAE-96-0060） needed to be further tested on farmers＇ field to obtain on-farm data, alter which it should be recommended for official registration and released by the National Committee on Naming, Registration and Release of Crop varieties in Nigeria.

关键词： Stability assessment environmental index genotype West African okra.

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Information Use and Knowledge of HIV/Hepatitis B Co-Infection in Lagos, Nigeria

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Health 2019年第6期11卷 671-682页

作者： Evaristus Adesina olusola Oyero Nelson Okorie Lanre Amodu Oladokun Omojola babatunde Adeyeye Department of Mass Communication Covenant University Ota Nigeria

Achieving the Sustainable Development Goal 3.3 is hinged on effective use of information sources for health communication interventions. This study investigated the knowledge of residents of Lagos Nigeria on HIV/HBV co-infection and the use of information sources. The study adopted the quantitative research method of survey to find out the knowledge level of residents of Lagos, Nigeria on the HIV/HBV co-infection. While the bivariate analysis presented cross tabular data on knowledge level, the multivariate was used to test highlight the hypothesis. The study indicated that more than 75% of the respondents had heard of HIV and HBV co-infection. The result established a significant relationship between the use of information sources and the knowledge on HBV/HIV co-infection. Despite the knowledge on HBV/HIV co-infection, the study concluded on the need for preventive information campaigns to create awareness to mitigate the increasing cases of HBV/HIV co-infection cum motivates individuals toward healthy lifestyle practices.

关键词： Hepatitis B Human Immunodeficiency Virus Information Use Knowledge Nigeria

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Maternal Plasma Lipid Profile in Women Screened for Gestational Diabetes Mellitus (GDM)

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Open Journal of Obstetrics and Gynecology 2017年第12期7卷 1209-1215页

作者： Adeniran Samuel Atiba babatunde Ajayi Olofinbiyi Akindele Rasaq Akintunde Aduloju olusola Peter Ojo Olubunmi Clementinah Akinlua Ibikunle Department of Chemical Pathology Ekiti State University Ado-Ekiti Nigeria Department of Obstetrics and Gynaecology Ekiti State University Ado-Ekiti Nigeria Department of Obstetrics and Gynaecology Ladoke Akintola University of Technology Ogbomoso Nigeria Department of Biochemistry Ekiti State University Ado-Ekiti Nigeria

Objective: This is to determine the plasma lipid profile status of patients diagnosed with gestational diabetes mellitus. Methodology: Seventy-nine pregnant women between gestational age of 24 and 28 weeks out of which 23 and 16 were diagnosed of having GDM using IADAPSG and WHO guidelines respectively were recruited into the study. Plasma lipid profile was determined among the study groups using standard laboratory techniques. Results: Higher numbers of women were diagnosed with GDM using IASDAPG criteria than when WHO criteria were used. Plasma lipid profile showed no significant difference between women with GDM and Non-GDM irrespective of guidelines used in the diagnosis of GDM. Conclusion: Pregnancy and Gestational Diabetes Mellitus may have influence on lipid metabolism but not likely in the second trimester of pregnancy as observed in our study.

关键词： Gestational Diabetes Mellitus Lipid Profile

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Outcome of Symptom-Based RT-PCR Testing for SARS-CoV-2: Experience from a Large Public Testing Centre in Nigeria

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Advances in Infectious Diseases 2022年第4期12卷 799-812页

作者： Aigbe Gregory Ohihoin Kazeem Adewale Osuolale Patrick Azuka Okwuraiwe Adesola Zaidat Musa Ayorinde babatunde James Chika Kingsley Onwuamah Olufemi Samuel Amoo Joseph Ojonugwa Shaibu Fehintola Ige Esther Ngozi Ohihoin Emelda Chukwu Ngozi Mirabel Otuonye Tajudeen Bamidele Adeola Olukosi olusola Ajibaye Yekeen Raheem David Oladele Agatha Nkiru David babatunde Adewale Rosemary Audu Oliver Ezechi Nkiruka Nnonyelum Odunukwe Richard Adegbola babatunde Lawal Salako Clinical Sciences Department Nigerian Institute of Medical Research Yaba Lagos Grants and M/E Unit (Biostatistics) Nigerian Institute of Medical Research Yaba Lagos Centre for Human Virology and Genomics Microbiology Department Nigerian Institute of Medical Research Yaba Lagos Department of Biochemistry and Nutrition Nigerian Institute of Medical Research Yaba Lagos Centre of Infectious Disease Research Microbiology Department Nigerian Institute of Medical Research Yaba Lagos Central Research Laboratory Nigerian Institute of Medical Research Yaba Lagos Department of Molecular Biology and Biotechnology Nigerian Institute of Medical Research Yaba Lagos Clinical Diagnostic Laboratory Nigerian Institute of Medical Research Yaba Lagos Department of Public Health Nigerian Institute of Medical Research Yaba Lagos

Background: Access to testing for SARS-CoV-2 in Nigeria is still highly restricted. Only patients who are symptomatic for SARS-CoV-2 are selected for testing. This pattern of testing will miss a large proportion of individuals with the infection who are asymptomatic and presymptomatic. This study reports the experience of a symptom-based study from a large testing centre in Nigeria. Methods: A cross-sectional study, reviewing data collected from respondents presenting at the Nigerian Institute of Medical Research (NIMR) modified drive-through center for COVID-19 test between the period March 31st and August 31st, 2020 were included in the analysis. Results: A total of 9891 participants were recruited into the study and 2465 participants (24.9%) had a positive PCR result for SARS-CoV-2. The majority of the respondents were above 18 years old, n = 9163 (93.4%). The average age of the respondents was 36.7 years (sd 13.8 years). The age of the participants has a significant effect on SARS-CoV-2 status (AOR = 1.009, CI, 1.005 to 1.012, p = 0.0001). There was a male preponderance, n = 5652 (57.6%). The odds of having a positive status for SARS-CoV-2 were 0.9 times lower for female participants. The majority of the respondents had a history of travel, n = 6788 (68.6%). Cough was the commonest symptom, n = 1062 (10.7%) followed by fever, n = 979 (9.9%). The mortality rate was 0.1%. Among the participants with comorbidity, 31 (51.7%) had positive results for SARS-CoV-2 while 29 (48.3%) had negative results. Conclusion: Symptom-based approach to testing for SARS-CoV-2 in Nigeria revealed a high positivity rate, while mortality from those tested in the study is low. Age and gender appear to play a significant role in the dynamics of the disease.

关键词： SARS-CoV-2 COVID-19 Symptoms RT-PCR Nigeria

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COVID-19 Spread Patterns Is Unrelated to Malaria Co-Infections in Lagos, Nigeria

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Advances in Infectious Diseases 2020年第4期10卷 200-215页

作者： Olufemi Samuel Amoo Olugbenga Olanrewaju Aina Azuka Patrick Okwuraiwe Chika Kingsley Onwuamah Joseph Ojonugwa Shaibu Fehintola Ige Kelly Owaneze Hammed Olanrewaju Agboola Dorcas Njeri Kareithi Tochukwu Ifeanyi Onuigbo Amaka Stephanie Ikemefuna Joy Isioma Oraegbu Ebenezer Olusoji Odewale Leona Chika Okoli olusola Ajibaye Ayorinde babatunde James Ganiyu Idris Greg Ohihoin Bosun Tijani Temmie Giwa-Tunbosun Richard Adegbola babatunde Lawal Salako Rosemary Ajuma Audu Centre for Human Virology and Genomics Microbiology Department Nigerian Institute of Medical Research Lagos Nigeria Biochemistry Department Nigerian Institute of Medical Research Lagos Nigeria Co-Creation Hub Lagos Nigeria Lifebank Lagos Nigeria

Malaria and COVID-19, though caused by different organisms, share a significant number of symptoms like fever, headaches, difficulty in breathing and fatigue. Therefore, determining if a patient is positive for COVID-19 or Malaria based on symptoms alone, might be misleading, especially during pandemic response. It has been reported that an individual begins to manifest Malaria symptoms between 10 - 15 days after infection with malaria parasite, although some individuals may be asymptomatic. Some COVID-19 infected patients, like Malaria, are also asymptomatic but could contribute to transmission of SARS-CoV-2 virus. These similarities in symptoms have led to misconception about COVID-19 being real and misdiagnoses of both infections, especially in Nigeria. However, there are possibilities that Malaria and COVID-19 could co-exist in some individuals thereby leading to mismanagement and treatment of only one infection while neglecting the possibility of the patient being infected with both diseases. We aim to determine possible correlation between Malaria and COVID-19 in a Malaria endemic country like Nigeria. This study was carried out using the qPCR molecular testing approach, a gold standard for COVID-19 testing and rapid diagnostic test kits to detect Malaria parasites in 617 individuals residing in urban settings. We demonstrated that COVID-19 and Malaria infection amongst adults in urban settings are unrelated thereby focusing on symptoms alone may result in misdiagnosis. Our findings show that Malaria is not among the underlying medical conditions strongly associated with increased risk for severe COVID-19 illness amongst adults in urban settings.

关键词： Malaria COVID-19 Symptoms

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