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Advances in Po.ar Science 2024年

作者： Sergio.So.o.ACU?A Alexander o.VARGAS Jo.atan KALUZA Co.sejo.Nacio.al de Investigacio.es Científicas y Técnicas (Co.ICET) Red Paleo.to.ógica U-Chile Departamento.de Bio.o.ía Facultad de Ciencias Universidad de Chile Fundación de Histo.ia Natural Félix de Azara Universidad Maimónides Escuela de Geo.o.ía Facultad de Ciencias Ingeniería y Tecno.o.ía Universidad Mayo. Pro.idencia

The first dino.aur disco.ered in the Antarctic co.tinent was the ankylo.aur Antarcto.elta o.ivero. in the 1980s. Nevertheless， since then several hypo.heses o. phylo.enetical relatio.ships have been pro.o.ed because these have been depended o. ho. the skeletal remains have been interpreted. The main o.stacle fo. clarifying its phylo.enetic po.itio. is that many po.tio.s o. the skeleto. remain unkno.n， in additio. to.the presence o. unkno.n characters in typical ankylo.aurs. Co.sidered an ankylo.aurid， no.o.aurid， o. even a chimaera， a recent pro.o.al based o. mo.tly co.plete material o. a new ankylo.aur fro. Chilean Patago.ia pro.ided suppo.t fo. a no.el phylo.enetic hypo.hesis: Antarcto.elta and o.her so.thern ankylo.aurs are an early branching clade， the Parankylo.auria， who.e o.igin pro.ably dates to.the Late Jurassic. In the light o. this new view， a redescriptio. o. the available skeletal remains is pro.ided to.ether with a new reco.structio. o. the first Antarctic dino.aur kno.n to.the science co.munity.

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Nutritio.al epigenetics educatio. impro.es diet and attitude o. parents o. children with autism o. attentio. deficit/hyperactivity diso.der

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Wo.ld Jo.rnal o. Psychiatry 2024年第1期14卷 159-178页

作者： Renee J Dufault Katherine M Adler David o.Carpenter Steven G Gilbert Raquel A Crider Co.lege o. Graduate Health Studies A.T.Still UniversityKirksvilleMO 63501United States Department o. Research Food Ingredient and Health Research InstituteNaalehuHI 96772United States Department o. Health Sciences University of New HavenWest HavenCT 06516United States Institute fo. Health and the Enviro.ment School of Public HealthState University of New YorkAlbanyNY 12222United States Department o. Research Institute of Neurotoxicology and Neurological DisordersSeattleWA 98105United States Department o. Statistics Food Ingredient and Health Research InstituteNaalehuHI 96772United States

BACKGRo.ND Unhealthy maternal diet leads to.heavy metal expo.ures fro. the co.sumptio. o. ultra-pro.essed fo.ds that may impact gene behavio. acro.s generatio.s,creating co.ditio.s fo. the neuro.evelo.mental diso.ders kno.n as autism and attentio. deficit/hyperactivity diso.der(ADHD).Children with these diso.ders have difficulty metabo.izing and excreting heavy metals fro. their blo.dstream,and the severity o. their sympto.s co.relates with the heavy metal levels measured in their *** may play a key ro.e in helping parents reduce their ultra-pro.essed fo.d and dietary heavy metal intake by pro.iding access to.effective nutritio.al epigenetics *** To.test the efficacy o. nutritio.al epigenetics instructio. in reducing parental ultra-pro.essed fo.d *** The study utilized a semi-rando.ized test and co.tro. gro.p pretest-po.ttest pilo. study design with participants recruited fro. parents having a learning-disabled child with autism o. ***-two.parents who.met the inclusio. criteria were rando.ly selected to.serve in the test(n=11)o. co.tro.(n=11)*** test gro.p participated in the six-week o.line nutritio.al epigenetics tuto.ial,while the co.tro. gro.p did *** efficacy o. the nutritio.al epigenetics instructio. was determined by measuring changes in parent diet and attitude using data derived fro. an o.line diet survey administered to.the participants during the pre and po.t interventio. *** intake sco.es were derived fo. bo.h ultra-pro.essed and who.e/o.ganic *** sample t-tests were co.ducted to.determine any differences in mean diet sco.es within each *** There was a significant difference in the diet sco.es o. the test gro.p between the pre-and po.t-interventio. *** parents in the test gro.p significantly reduced their intake o. ultra-pro.essed fo.ds with a preinterventio. diet sco.e o. 70(mean=5.385,SD=2.534)and a po.t-interventio. diet sco.e o. 113(mean=8.692,SD=1.750)and the

关键词： Epigeno.ics Parenteral nutritio. Autism Attentio. deficit/hyperactivity diso.der Ultra-pro.essed fo.ds Heavy metals

Hypo.halamic circuits and aging:keeping the circadian clo.k updated

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Neural Regeneratio. Research 2024年第9期19卷 1919-1928页

作者： Ro.a Vázquez-Lizarraga Lucia Mendo.a-Vivero. Caro.ina Cid-Castro.Sareni Ruiz-Mo.to.a Erick Carreño.Vázquez Ricardo.o.o.co.So.is Instituto.Nacio.al de Medicina Genómica(INMEGEN) México CityMéxico Centro.de Investigacío. so.re el Envejecimiento Centro de Investigacíon y de Estudios Avanzados(CIE-CINVESTAV)México CityMéxico Instituto.de Investigacio.es Bio.édicas Universidad Nacional Autónoma de México UNAMMéxico CityMéxico

o.er the past century,age-related diseases,such as cancer,type-2 diabetes,o.esity,and mental illness,have sho.n a significant increase,negatively impacting o.erall quality o. *** o. aged animal mo.els have unveiled a pro.ressive disco.rdinatio. at multiple regulato.y levels,including transcriptio.al,translatio.al,and po.t-translatio.al pro.esses,resulting fro. cellular stress and circadian *** circadian clo.k emerges as a key regulato.,sustaining physio.o.ical ho.eo.tasis and pro.o.ing healthy aging thro.gh timely mo.ecular co.rdinatio. o. pivo.al cellular pro.esses,such as stem-cell functio.,cellular stress respo.ses,and inter-tissue co.municatio.,which beco.e disrupted during *** the crucial ro.e o. hypo.halamic circuits in regulating o.ganismal physio.o.y,metabo.ic co.tro.,sleep ho.eo.tasis,and circadian rhythms,and their dependence o. these pro.esses,strategies aimed at enhancing hypo.halamic and circadian functio.,including pharmaco.o.ical and no.-pharmaco.o.ical appro.ches,o.fer systemic benefits fo. healthy *** brain-directed drug administratio. represents a pro.ising avenue fo. effectively targeting specific brain regio.s,like the hypo.halamus,while reducing side effects asso.iated with systemic drug delivery,thereby presenting new therapeutic po.sibilities fo. diverse age-related co.ditio.s.

关键词： aging astro.ytes cellular stress respo.ses circadian clo.k hypo.halamus intranasal drug administratio. metabo.ic co.tro. nutrient senso. SIRT1 sleep ho.eo.tasis

Evidence o. the Great Attracto. and Great Repeller fro. Artificial Neural Netwo.k Imputatio. o. Slo.n Digital Sky Survey

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Jo.rnal o. High Energy Physics, Gravitatio. and Co.mo.o.y 2024年第3期10卷 1178-1194页

作者： Christo.her Cillian o.Neill Scho.l o. Co.puting Ulster University Belfast UK Data Analysis CCT Dublin Ireland

The Slo.ne Digital Sky Survey (SDSS) has been in the pro.ess o. creating a 3D digital map o. the Universe, since 2000AD. Ho.ever, it has no. been able to.map that po.tio. o. the sky which is o.cluded by the dust gas and stars o. o.r o.n Milkyway Galaxy. This research builds o. wo.k fro. a previo.s paper that so.ght to.impute this missing galactic info.matio. using Inpainting, po.ar transfo.ms and Linear Regressio. ANNs. In that paper, the autho. o.ly attempted to.impute the data in the No.thern hemisphere using the ANN mo.el, which subsequently co.firmed the existence o. the Great Attracto. and the ho.o.eneity o. the Universe. In this paper, the autho. has imputed the So.thern Hemisphere and disco.ered a regio. that is mo.tly devo.d o. stars. Since this area appears to.be the co.nterpart to.the Great Attracto., the autho. refers to.it as the Great Repeller and po.tulates that it is an area o. physical repulsio., inline with the wo.k o. GerdPo.merenke and o.hers. Finally, the paper investigates large scale structures in the imputed galaxies.

关键词： Artificial Neural Netwo.ks Co.vo.utio.al Neural Netwo.ks SDSS Aniso.ro.ies Great Attracto.

Actio.able Geno.ypes and Their Asso.iatio. with Life Span in Iceland

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四川生理科学杂志 2024年第4期46卷 208-208页

作者： Brynjar o.Jensso. Fro. deCo.E Genetics-Amgen (B.o.J. G.A.A. H.K. R.F. H. Helgason A.O. G.S. H.P.E. G.H.H. B.A.A. H.J. G.R.O. A. Sturluson S.A.G. G.A.T. F.Z. K.H.S.M. G.P. A. Sigurdsson Adalbjorg Jonasdottir Aslaug Jonasdottir M.K.M. A. Helgadottir V.S. J.G. S.N.S. D.O.A. J.S. O.T.M. G.M. B.V.H. A. Helgason H.S. I.J. H. Holm T.R. U.T. D.F.G. K.S. P.S.) the Faculty of Medicine School of Health Sciences (G.A.A. M.K.M. R.H. D.O.A. I.J. U.T. K.S.) the Department of Anthropology (K.H.S.M. A. Helgason) and the School of Engineering and Natural Sciences (H. Helgason G.H.H. D.F.G.) University of Iceland the Departments of Urology (R.H.) Clinical Biochemistry (I.O.) Oncology (O.T.J.) Medicine (D.O.A.) and Immunology (I.J.) Landspitali-the National University Hospital of Iceland and the School of Science and Engineering Reykjavik University (B.V.H.) - all in Reykjavik Iceland.

Backgro.nd:In 2021,the American Co.lege o. Medical Genetics and Geno.ics(ACMG)reco.mended repo.ting actio.able geno.ypes in 73 genes asso.iated with diseases fo. which preventive o. therapeutic measures are *** o. the... 详细信息

关键词： Co.lege actio. Ice

Applying a Co.text-based Metho. to.Build a Kno.ledge Graph fo. the Blue Amazo.

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Data Intelligence 2024年第1期6卷 64-103页

作者： Pedro.de Mo.aes Ligabue Anaro.a Alves Franco.Brandão.Sarajane Marques Peres Fabio.Gagliardi Co.man Paulo.Piro.elli Esco.a Po.itécnica Universidade de São PauloRua Visconde da Luz60São PauloSão Paulo 05508-010Brazi Esco.a Po.itécnica Universidade de São PauloAv.Prof.Luciano Gualbertotv 3158São Paulo 05508-010Brazil Esco.a de Artes Ciências e Humanidades Universidade de São PauloRua Arlindo Béttio1000São Paulo 03828-000Brazil Instituto.de Estudo. Avançado. Universidade de São PauloRua da Praça do Relógio109São Paulo 05508-050Brazil

Kno.ledge graphs are emplo.ed in several tasks,such as questio. answering and reco.mendatio. systems,due to.their ability to.represent relatio.ships between *** co.structing such a graphs,ho.ever,remains an unreso.ved challenge within kno.ledge *** tackle this challenge,we pro.o.e CtxKG,a metho. specifically aimed at extracting kno.ledge graphs in a co.text o. limited reso.rces in which the o.ly input is a set o. unstructured text *** is based o. o.enIE(a relatio.ship triple extractio. metho.)and BERT(a language mo.el)and co.tains fo.r stages:the extractio. o. relatio.ship triples directly fro. text;the identificatio. o. syno.yms acro.s triples;the merging o. similar entities;and the building o. bridges between kno.ledge graphs o. different *** metho. distinguishes itself fro. tho.e in the current literature(i)thro.gh its use o. the parse tree to.avo.d the o.erlapping entities pro.uced by base implementatio.s o. o.enIE;and(ii)thro.gh its bridges,which create a co.nected netwo.k o. graphs,o.erco.ing a limitatio. similar metho.s have o. o.e iso.ated graph per *** co.pare o.r metho. to.two.o.hers by generating graphs fo. mo.ie articles fro. Wikipedia and co.trasting them with benchmark graphs built fro. the o.Db mo.ie *** results suggest that o.r metho. is able to.impro.e multiple aspects o. kno.ledge graph *** also.highlight the critical ro.e that triple identificatio. and named-entity reco.nitio. have in impro.ing the quality o. auto.atically generated graphs,suggesting future paths fo. ***,we apply CtxKG to.build BlabKG,a kno.ledge graph fo. the Blue Amazo.,and discuss po.sible impro.ements.

关键词： kno.ledge graph wo.d embeddings relatio.ship triple extractio. Blue Amazo. Atlantic o.ean Brazilian co.st

Influence o. railway wheel tread damage o. wheel-rail impact lo.ds and the durability o. wheelsets

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Railway Engineering Science 2024年第1期32卷 20-35页

作者： Michele Maglio.To.e Vernersso. Jens C.o.Nielsen Anders Ekberg Elena Kabo CHARMEC Department of Mechanical and Maritime SciencesChalmers University of TechnologySE‑41296 GothenburgSweden

Dynamic wheel-rail co.tact fo.ces induced by a severe fo.m o. wheel tread damage have been measured by a wheel impact lo.d detecto. during full-scale field tests at different vehicle *** o. laser scanning,the measured three-dimensio.al damage geo.etry is emplo.ed in simulatio.s o. dynamic vehicle-track interactio. to.calibrate and verify a simulatio. *** relatio. between the magnitude o. the impact lo.d and vario.s o.eratio.al parameters,such as vehicle speed,lateral po.itio. o. wheel-rail co.tact,track stiffness and po.itio. o. impact within a sleeper bay,is *** calibrated mo.el is later emplo.ed in simulatio.s featuring o.her fo.ms o. tread damage;their effects o. impact lo.d and subsequent fatigue impact o. bearings,wheel webs and subsurface initiated ro.ling co.tact fatigue o. the wheel tread are *** results quantify the effects o. wheel tread defects and are valuable in a shift to.ards co.ditio.-based maintenance o. running gear,and fo. general assessment o. the severity o. different types o. railway wheel tread damage.

关键词： Wheel tread damage Ro.ling co.tact fatigue cluster Field measurements Dynamic vehicle-track interactio. Wheel-rail impact lo.d Wheelset durability

No.linear Study o. the Mechanical Perfo.mance o. Built-Up Co.d-Fo.med Steel Co.crete-Filled Co.umns under Co.pressio.

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Co.puter Mo.eling in Engineering & Sciences 2024年第6期139卷 3435-3465页

作者： o.lfa Harrat Yazid Hadidane S.M.Anas Nadhim Hamah So. Ahmed Faro.k Deifalla Paul o.Awo.era Nadia Go.ider Civil Engineering Labo.ato.y Faculty of TechnologyDepartment of Civil EngineeringBadji Mokhtar-Annaba UniversityP.O.Box 12Annaba23000Algeria Department o. Civil Engineering Faculty of Engineering and TechnologyJamia Millia Islamia(A Central University)New Delhi110025India Civil Engineering Department University of GarmianKalar46021Iraq Department o. Civil Engineering Harran UniversitySanliurfa63510Turkey Structural Engineering and Co.structio. Management Department Future University in EgyptNew Cairo11835Egypt Department o. Civil Engineering Covenant UniversityOta112233Nigeria

Given their numero.s functio.al and architectural benefits,such as impro.ed bearing capacity and increased resistance to.elastic instability mo.es,co.d-fo.med steel(CFS)built-up sectio.s have beco.e increasingly develo.ed and used in recent years,particularly in the co.structio. *** paper presents an analytical and numerical study o. assembled CFS two.single channel-shaped co.umns with different slenderness and co.figuratio.s(backto.back,face-to.face,and bo.).These co.umns were jo.ned by do.ble-ro. rivets fo. the back-to.back and bo. co.figuratio.s,whereas they were welded to.ether fo. the face-to.face *** built-up co.umns were filled with o.dinary co.crete o. go.d *** element mo.els were applied,using ABAQUS so.tware,to.assess mechanical perfo.mance and study the influence o. assembly techniques o. the behavio. o. co.d-fo.med co.umns under axial *** appro.ches based o. Euro.o.e 3 and Euro.o.e 4 reco.mendatio.s fo. un-filled and co.crete-filled co.umns respectively were fo.lo.ed fo. the numerical analysis,and co.crete co.finement effects were also.co.sidered per American Co.crete Institute(ACI)standards fo. face-to.face and bo. *** o.tained results indicated a go.d co.relatio. between the numerical results and the pro.o.ed analytical metho.o.o.y which did no. exceed 8%.The failure mo.es sho.ed that the co.umns failed due to.instabilities such as lo.al and glo.al buckling.

关键词： Co.d-fo.med steel built-up sectio.s slenderness rivets welded axial co.pressio. analytical appro.ches co.finement buckling

Co.tributio. o. mechanical fo.ces to.structural synaptic plasticity:insights fro. 3D cellular mo.ility mechanisms

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Neural Regeneratio. Research 2025年第7期20卷 1995-1996页

作者： Rita o.Teo.o.o.Mafalda Ribeiro.Ramo. Lara Carvalho iNo.A4Health NOVA Medical School|Faculdade de Ciências MédicasNMS|FCMUniversidade Nova de LisboaLisboaPortugal

Cells,tissues,and o.gans are co.stantly subjected to.the actio. o. mechanical fo.ces fro. the extracellular enviro.ment-and the nervo.s system is no.***-intrinsic pro.erties such as membrane lipid co.po.itio.,abundance o. mechano.enso.s,and cyto.keletal dynamics make cells mo.e o. less likely to.sense these *** and extrinsic cues are integrated by cells and this co.bined info.matio. determines the rate and dynamics o. membrane pro.rusio. gro.th o. retractio.(Yamada and Sixt,2019).Cell pro.rusio.s are extensio.s o. the plasma membrane that play crucial ro.es in diverse co.texts such as cell migratio. and neuro.al synapse *** the nervo.s system,neuro.s are highly dynamic cells that can change the size and number o. their pre-and po.tsynaptic elements(called synaptic bo.to.s and dendritic spines,respectively),in respo.se to.changes in the levels o. synaptic activity thro.gh a pro.ess called *** plasticity is a hallmark o. the nervo.s system and is present thro.gho.t o.r lives,being required fo. functio.s like memo.y fo.matio. o. the learning o. new mo.o. skills(Minegishi et al.,2023;Pillai and Franze,2024).

关键词： plasticity structural mechanisms

Green retro.itting o. heritage buildings based o.(3Ts)framewo.k:An applied case study

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Fro.tiers o. Architectural Research 2024年第4期13卷 776-798页

作者： Alaa o.Shehata Asmaa M.Hassan Merhan M.Shahda Naglaa A.Megahed Architectural Engineering and Urban Planning Department Faculty of EngineeringPort Said UniversityPort SaidEgypt

Diverse heritage architecture characterizes Po.t Said in Egypt,reflecting Euro.ean and Arab *** Canal heritage villas co.prise 25%o. the to.al listed heritage buildings in the ***,it is impo.tant to.retro.it them,aligning with the Sustainable Develo.ment Go.ls(SDGs).By reviewing the previo.s literature related to.the green retro.itting o. heritage buildings,the(3Ts)framewo.k can be co.sidered a ho.istic framewo.k that co.ers the latest trends due to.its three co.po.ents:targets,to.ls,and tasks,which help the success o. the pro.ess thro.gh a ho.istic visio. o. suppo.ting building info.matio. mo.eling(BIM)techno.o.ies and o.ganizing stakeho.ders’*** paper aims to.apply the(3Ts)framewo.k to.Suez Canal heritage villas in Po.t Said,*** applied study is based o. ho. stakeho.ders perceive their input and decisio.-making,measuring the climate parameters,pro.o.ing several green retro.its,and integrating them into.green *** o. scenario. is co.ducted by utilizing the Design Builder simulatio. ***,the Skelio. plugin calculates the pho.o.o.taic system’s(PVs)energy *** results indicated that the to.al energy savings co.ld reach appro.imately 12%e74%and nearly 10%e73%Co.emissio.s reductio. witho.t affecting heritage values.

关键词： Green retro.itting Heritage buildings BIM BES Suez Canal heritage villas Po.t Said/Egypt