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Journal of Integrative Nursing 2023年第3期5卷 210-215页

作者： Patricia Obiajulu ONIANWA Folashade Omobisi Mary AKANBI Mary Oyenike AYORINDE Oluwatosin Esther JOHN olufunke olabisi are Ogonna Eze OJERINDE Sariyat Yetunde ALAKA Department of Clinical Nursing University College HospitalIbadanNigeria

Objective:This study assessed the level of nurses’knowledge of the prevention of venous thromboembolism(VTE)in a tertiary health *** and Methods:This descriptive cross-sectional study was conducted with 328 eligible respondents,selected using a random sampling method in a teaching hospital in Nigeria.A self-administered structured questionnaire was used to collect data on the basic knowledge,risk factors,and preventive measures of ***:Findings from the study revealed that 51.2%scored above the mean score of 28.6±*** educational status of the respondents had a significant influence on their knowledge of risk factors of VTE(F=4.696,P=0.031).Conclusion:The overall knowledge of nurses is satisfactory,although the majority could not answer correctly questions on the administration of prefilled anticoagulants and identification of some key risk factors of VTE.

关键词： Deep vein thrombosis hospital-associated nursing pulmonary embolism venous thromboembolism

A synergistic effect of zinc oxide nanoparticles and polyethylene butene improving the rheology of waxy crude oil

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Petroleum Research 2023年第2期8卷 217-225页

作者： Toyin olabisi Odutola University of Port Harcourt Nigeria

This research examined the use of 75 nm zinc oxide nanoparticles(nano ZnO)and polyethylene butene(PEB)to decrease the viscosity of Nigerian waxy crude *** rheology of the crude oil was assessed by measuring the viscosity and shear stress of samples containing PEB at 500,1000,2000,3000,4000 or 5000 ppm and nano ZnO at 1,2,3 or 4 wt% between 10 and 35℃ at shear rates from 1.7 to 1020 s^(-1).Rheological modeling indicated that a power law pseudoplastic model was the best fit for the experimental data,giving a regression coefficient of *** addition of these inhibitors induced Newtonian fluid behavior in the crude samples such that the shear stress-shear rate relationship plots were linear at all *** optimum concentrations of the inhibitors in this study were 2000 ppm PEB(providing a 33% viscosity reduction)and 1 wt% nano ZnO(providing a 26% viscosity reduction).A combination of these additives at these concentrations provided a synergistic effect and gave a greater viscosity reduction of 41%.This work demonstrates that a blend of ZnO nanoparticles and PEB can improve the flowability of waxy crude.

关键词： Flow assurance Wax prevention Zinc oxide nanoparticles Poly ethylene butene Niger Delta waxy crude

Anticancer potential of metabolic compounds from marine actinomycetes isolated from Lagos Lagoon sediment

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Journal of Pharmaceutical Analysis 2019年第3期9卷 201-208页

作者： olabisi Flora Davies-Bolorunduro Isaac Adeyemi Adeleye Moshood Olushola Akinleye Peng George Wang Department of Microbiology University of Lagos Akoka Lagos Nigeria Department of Pharmaceutical Chemistry University of Lagos Idi-Araba Lagos Nigeria Department of Chemistry Georgia State University Atlanta GA United States

Thirty-two actinomycetes strains were isolated from sediment samples from 12 different sites at Lagos Lagoon and identified using standard physiological and biochemical procedures as well as 16S rDNA gene sequence analysis. Secondary metabolites were extracted from the strains and their anticancer activity on the K562 (Human acute myelocytic leukemia), HeLa (cervical carcinoma), AGS (Human gastric), MCF- 7 (breast adenocarcinoma) and HL-60 (Human acute promyelocytic leukemia) cell lines was determined. The metabolic extracts exhibited cytotoxicity with IC50 values ranging from 0.030 mg/mL to 4.4 mg/mL. The Streptomyces bingchenggensis ULS14 extract was cytotoxic against all the cell lines tested. The bioactivity-guided extraction and purification of the metabolic extracts from this strain yielded two purified anticancer compounds: ULDF4 and ULDF5. The structures of the extracted compounds were determined using spectroscopic analyses, including electrospray ionization mass spectrophotometer and nuclear magnetic resonance (1 Dimensional and 2 Dimensional), and were shown to be structurally similar to staurosporine and kigamicin. The IC50 of ULDF4 and ULDF5 against the HeLa cell line was 0.034 mg/mL and 0.075 mg/mL, respectively. This study is the first to reveal the anticancer potential of actinomycetes from Lagos Lagoon, which could be exploited for therapeutic purposes.

关键词： Streptomyces bingchenggensis ULS14 Metabolic extracts Cytotoxicity Spectroscopy Kigamicin Staurosporine

Spatial distribution and potential ecological and health risks associated with heavy metals in the Ijero-Ekiti mining site,Nigeria

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Regional Sustainability 2024年第1期5卷 26-41页

作者： Johnson Adedeji OLUSOLA Adeyinka Oluyemi ATURAMU olufunke ASAOLU Olusesan Sola OGUNLEYE Department of Geography and Planning Science Ekiti State UniversityAdo Ekiti360211Nigeria Institute of Ecology and Environmental Studies Obafemi Awolowo UniversityIle IfeOsun State220101Nigeria Department of Geology(Climate Change and Paleobiology Group) Ekiti State UniversityAdo Ekiti360211Nigeria Environmental Natural Resources and Blue EconomyEurope and Central AsiaWorld Bank GroupWashington D.C.20433the USA

Artisanal gold mining,a labor-intensive and antiquated technique,is a growing industry and the source of income for rural communities all over the ***,artisanal gold mining has potential negative and long-term effects on economy,environment,and *** study collected soil samples from 16 sample points including a control point to examine the pollution degrees and spatial distribution of heavy metals,as well as ecological and health risks associated with heavy metal pollution in the Ijero-Ekiti mining site,*** Information System(GIS)and remote sensing technologies were used to identify regions with high concentrations of heavy metals and assess the environmental impact of gold mining *** results show that the mean heavy metal concentrations of 16 soil pointa are 8.94(±5.97)mg/kg for As,0.18(±0.54)mg/kg for Cd,0.11(±1.06)mg/kg for Co,14.32(±3.43)mg/kg for Cr,6.89(±0.64)mg/kg for Cu,48.92(±11.77)mg/kg for Fe,135.81(±30.75)mg/kg for Mn,5.92(±0.96)mg/kg for Ni,5.72(±1.66)mg/kg for Pb,and 13.94(±1.38)mg/kg for *** study reveals that heavy metal concentration in soils follows the order of Mn>Fe>Cr>Zn>As>Cu>Ni>Pb>Co>*** analysis of soil samples indicates that 3 principal components(PCs)account for 70.008%of the total variance and there are strong positive correlations between various pairs of heavy *** total potential ecological risk index(309.599)in the study area is ***-carcinogenic risk suggests that there may be long-term health impacts on people who work in the mining areas due to chronic exposure to the *** on the study,the hazard index of carcinogenic health risks associated with heavy metals through ingestion is 520.00×10^(–4).Dermal contact from As and Cr also increases the risk of cancer,with the highest hazard index value of 18.40×10^(–4).The lowest exposure pathway,with the hazard index value of 0.68×10^(–4),indicates that the inhalation of heavy metals has a comparatively low risk of can

关键词： Artisanal gold mining Heavy metals Exposure pathway Potential ecological risk Geo-accumulation index Ijero-Ekiti mining site

Hyoscyamine-producing marine Actinomycetes from Lagos Lagoon sediment

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Asian Pacific Journal of Tropical Biomedicine 2015年第3期5卷 196-201页

作者： Davies olabisi Flora Adeleye Isaac Adeyemi Wang Peng George Department of Microbiology.University of Lagos Department of Chemistry Georgia State University

Objective:To isolate and screen Actinoniycetes from Lagos Lagoon soil sediments for production of bioactive ***:Sediment samples were collected from four different locations of Lagos Lagoon and were dried for 2 weeks after which the Actinoniycetes were isolated by serial dilution using the spread plate method on starch casein and Kuster's agar supplemented with 80 ug/mL cycloheximide to prevent fungal *** plates were incubated at 28 C for 1-2 *** were selected based on their colonial characteristics as well as their Gram's reaction and subciiltured using the same media for isolation until pure cultures were obtained and incubated at 28 C for 3 ***,they were inoculated into starch casein and Kuster's broth media and incubated for 8 *** secondary metabolites were screened for antimicrobial activity against the following microorganisms:methicillin resistant Staphylococcus *** aureus ATCC *** coli ATCC *** aeruginosa ATCC *** albicans and Enterocolitis faecal is ATCC *** staphylococci isolated from HIV patients were also used(Staphylococcus *** xylosus and Staphylococcus epidennidis).The antimicrobial metabolites of the Actinoniycetes isolates were identified using gas chromatography(GC).Results:Crude extracts of isolates showed antimicrobial activity against some of the test *** GC data analysis showed the antibiotic profile of these ***:Analysis of the crude extracts of the isolates using GC method,revealed the presence of antibiotics including an anticholinergic hyoscyamine among other conclusions.

关键词： Marine Actinomycetes Streptomyces Antimethicillin resistance Molecular identification Morphological characteristics Gas chromatography

Chemical Compositions of <i>Lonchocarpus cyanescens</i>Benth., (Fabaceae)—Case Study of Its Volatile Oils, and Two Triterpenoids

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American Journal of Plant Sciences 2013年第8期4卷 1653-1659页

作者： Dorcas olufunke Moronkola Ibrahim Adebayo Oladosu Department of Chemistry University of Ibadan Ibadan Nigeria.

Leaf and stem essential oils of Lonchocarpus cyanescens Benth., (Fabaceae) were obtained by hydro-distillation, using all-glass apparatus adapted to British Pharmacopeia specifications with yields of 0.03% and 0.17% respectively. The oils were investigated by GC and GC-MS analyses. Results show seven compounds were responsible for 90.4% of leaf;eleven compounds responsible for 97.6% of stem volatile oils. Phytol (62.5%) and hexadecanoic acid (12.4%) dominate the leaf oil;octadecenoic (24.1%) and hexadecanoic acids (17.2%) are predominant in the stem oil. Phytochemical screening of stem, leaf, and root methanol extracts of Lonchocarpus cyanescens reveal presence of following seven classes of metabolites: saponin, tannin, steroid, terpenoid, cardiac glycosides, phlobatannins and flavonoids. Partitioning of methanol extract from dried leaf of it with ethylacetate gave fraction, which was chromatographed using gradient elution. TLC with high Rf was used in monitoring elution. Two white crystalline solids eluted at 5% and 10% ethylethanoate in hexane, were re-crystallized and characterized. They were subjected to Infra-Red spectra, mass spectrometry (ESI technique), 1H and 13C-NMR analyses, which confirmed they are triterpenoids. Above mentioned metabolites may be responsible for literature acclaimed bio-activities L. cyanescens display [anti-inflammatory, anti-arthritic, anti-microbial effects]. This paper presents details of above results which are new in literature.

关键词： Lonchocarpus cyanescens Fabaceae Antimalaria Phytochemistry Essential Oils GC GC-MS HPLC IR 1H and 13C-NMR

Technological Stressors in Developing Countries

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Open Journal of Applied Sciences 2016年第4期6卷 248-259页

作者： Ayodeji Akinlolu Agboola Omoneye olufunke Olasanmi Department of Management and Accounting Obafemi Awolowo University Ile-Ife Nigeria

Stress as a state of anxiety is produced when responsibilities do not match expected knowledge, and hence challenges one’s coping abilities. Job stress can be as a result of the nature of the job (work) or can result from the workers commonly referred to as dispositional stress. Stressors are conditions or situations which trigger stress response. Stressors can be inherent in the job due to factors affecting the occupation. This paper therefore highlights impact of technological stress (technostress) in auditing firm in developing countries.

关键词： Stress Stressors Auditing Ergonomic Hazards Management Performance

Terminal-Modality-Based Joint Call Admission Control Algorithm for Fair Radio Resource Allocation in Heterogeneous Cellular Networks

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International Journal of Communications, Network and System Sciences 2012年第7期5卷 392-404页

作者： olabisi E. Falowo Department of Electrical Engineering University of Cape Town Cape Town South Africa

There is a problem of unfairness in allocation of radio resources among heterogeneous mobile terminals in heterogeneous wireless networks. Low-capability mobile terminals (such as single-mode terminals) suffer high call blocking probability whereas high-capability mobile terminals (such as quad-mode terminals) experience very low call blocking probability, in the same heterogeneous wireless network. This paper proposes a Terminal-Modality-Based Joint Call Admission Control (TJCAC) algorithm to reduce this problem of unfairness. The proposed TJCAC algorithm makes call admission decisions based on mobile terminal modality (capability), network load, and radio access technology (RAT) terminal support index. The objectives of the proposed TJCAC algorithm are to reduce call blocking/dropping probability, and ensure fairness in allocation of radio resources among heterogeneous mobile terminals in heterogeneous networks. An analytical model is developed to evaluate the performance of the proposed TJCAC scheme in terms of call blocking/dropping probability in a heterogeneous wireless network. The performance of the proposed TJCAC algorithm is compared with that of other JCAC algorithms. Results show that the proposed algorithm reduces call blocking/dropping probability in the networks, and ensure fairness in allocation of radio resources among heterogeneous terminals.

关键词： Call Admission Control Terminal Modality Heterogeneous Terminals Radio Access Technology Call Dropping Call Blocking Markov Chain Mobile Users

Updates on management of pediatric obstructive sleep apnea

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Pediatric Investigation 2019年第4期3卷 228-235页

作者： Jason L.Yu olufunke Afolabi-Brown Department of Otorhinolaryngology-Head and Neck Surgery Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPAUSA Division of Sleep Medicine Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPAUSA Division of Pulmonary Medicine Children's Hospital of PhiladelphiaPhiladelphiaPAUSA Department of Pediatrics Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPAUSA

Obstructive sleep apnea(OSA)affects about 1%-5%of the pediatric *** consequences of untreated OSA in children include neurocognitive deficits,behavioral problems,poor school performance as well as systemic and pulmonary *** treatment options for pediatric OSA are numerous with a variety of surgical and non-surgical *** our understanding of the complexities of OSA grows,the options for management have continued to expand as *** objectives of this review are to describe the commonly prescribed treatments for pediatric OSA including adenotonsillectomy as well as use of positive airway *** also highlight other surgical and non-surgical interventions *** addition,we provide updates on current research focusing on newer diagnostic and experimental treatment modalities.

关键词： Obstructive sleep apnea Sleep disordered breathing Polysomnography Adenotonsillectomy Pediatric

Fast Fourier Transform of Multi-Assets Options under Economic Recession Induced Uncertainties

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American Journal of Computational Mathematics 2019年第3期9卷 143-157页

作者： Philip Ajibola Bankole olabisi O. Ugbebor Department of Mathematics University of Ibadan Ibadan Nigeria

A Fast Fourier transform approach has been presented by Carr & Madan (2009) on a single underlying asset. In this current research paper, we present fast Fourier transform algorithm for the valuation of Multi-asset Options under Economic Recession Induced Uncertainties. The issue of multi-dimension in both finite and infinite case of Options is part of the focus of this research. The notion of economic recession was incorporated. An intuition behind the introduction of recession induced volatility uncertainty is revealed by huge volatility variation during the period of economic recession compared to the period of recession-free. Nigeria economic recession outbreak in 2016 and its effects on the uncertainty of the payoffs of Nigeria Stocks Exchange (NSE) among other investments was among the motivating factors for proposing economic recession induced volatility in options pricing. The application of the proposed Fast Fourier Transform algorithm in handling multi-assets options was shown. A new result on options pricing was achieved and capable of yielding efficient option prices during and out of recession. Numerical results were presented on assets in 3-dimensions as an illustration taking Black Scholes prices as a bench mark for method effectiveness comparison. The key findings of this research paper among other crucial contributions could be seen in computational procedure of options valuation in multi-dimensions and uncertainties in options payoffs under the exposure of economic recession.

关键词： Fast Fourier Transform (FFT) Multi-Assets Finite and Infinite Dimension of Assets Economic Recession Volatility Change European Options