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蛋白尿和心电图左心室肥厚程度的减轻可独立地改善高血压的预后:LIFE研究

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世界核心医学期刊文摘（心脏病学分册） 2006年第9期2卷 55-56页

作者： olsen m.h. Wachtell K. Ibsen h. 韩瑞娟 Department m of Internal medicine Copenhagen University HospitalRingvejenDK-2600 GlostrupDenmark.Dr

Background: In the Losartan Intervention For Endpoint reduction in hypertensio n(LIFE) study, reduced urine albumin/ creatinine ratio(UACR) as well as regressi on of left ventricular hypertrophy have been associated with lower incidence of cardiovascular events. We wanted to investigate whether these prognostic improve ments were independent. methods: In 6679 hypertensive patients included in the L IFE study,we measured UACR, left ventricular hypertrophy by electrocardiography, serum cholesterol, plasma glucose and blood pressure after 2 weeks of placebo t reatment and again after 1 year of anti-hypertensive treatment with either an a tenolol-or a losartan-based regimen. During this first year of treatment, 77 p atients encountered a non-fatal stroke or myocardial infarction and were exclud ed to avoid bias. During the next 3-4 years, 610 composite endpoints[cardiovasc ular death(n=228), fatal or non-fatal myocardial infarction or stroke] were rec orded. Results: In Cox regression analyses, the composite endpoint was after adj ustment for treatment allocation predicted by baseline logUACR[hazard ratio(hR)= 1.16 per 10-fold increase, PhR=1.29 per 10-fold incre ase), baseline Sokolow-Lyon voltage(hR=1.01 per mm, both PhR=1.01 per 100 mm x ms, Ph was pred icted by 1-year logUACR(hR=1.59, PhR=1 .01, P=0.06) and 1-year Cornell product(hR=1.02, Ph were predicted independent of age, Framingham risk score, current smoking, history of cardiova scular disease and diabetes. Gender, serum cholesterol, plasma glucose and blood pressure did not enter the models. Conclusions: Baseline UACR and Sokolow-Lyon voltage, as well as in-treatment UACR and Cornell product, added to the risk p rediction independent of traditional risk factors, indicating that albuminuria a nd left ventricular hypertrophy reflect different aspects of cardiovascular dama

关键词：高血压患者左心室肥厚肥厚程度心电图预后减轻致死性心肌梗死蛋白尿

N-末端脑利钠肽是高血压和左室肥厚患者发生心血管事件的预测因素:LIFE研究

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世界核心医学期刊文摘（心脏病学分册） 2005年第1期1卷 55-56页

作者： olsen m.h. Wachtell K. Tuxen C. 陈云茹 Dept. Clin. Physiol. a nd Nucl. med. Glostrup University Hospital DK-2600 Glostrup DenmarkDr.

Background: N-terminal pro-brain natriuretic peptide (NtproBNP) and N -termi nal pro-atrial natriuretic peptide (Nt-proANP) are strong cardiovascular risk markers in patients with chronic heart failure, as well as in the general popula tion. We investigated whether high Nt-proBNP or NtproANP could also predict the composite endpoint (CEP) of cardiovascular death, non-fatal stroke or non-fat al myocardial infarction in patients with hypertension and left ventricular (LV) hypertrophy. methods: After 2 weeks of placebo treatment, clinical, laboratory and echocardiographic variables were assessed in 183 hypertensive participants i n the LIFE echo substudy with electrocardiographic LV hypertrophy. Nt-proBNP an d Nt-proANP were measured by immunoassay at baseline. The patients were followe d for 60 ±5 months. Results: Using Cox regression analysis, the 25 CEP were pre dicted by In(Nt-proBNP) (hazard ratio 1.61 per 2.73-fold increase, P hazard ratio 2.93, P he m edian value of 21.8 pmol/ml was associated with higher incidence of CEP (19.6 versus 7.7%, P he median value was associated with higher incidence of CEP in the 123 patients without history of diabetes or cardiovascular diseas e (14.8 versus 4.3%, P he association was insignificant in the 60 patients with a history of diabetes or cardiovascular disease (26.3 versus 18.2 %, NS). Nt-proANP showed the same tendency. Conclusion: Nt-proBNP, more than Nt-proANP, strongly predicts cardiovascular events in patients with hypertensio n and LV hypertrophy, especially in patients without diabetes or clinically over t cardiovascular disease.

关键词： N-末端左室肥厚患者 LIFE 脑利钠肽心血管事件复合终点致命性心肌梗死慢性心衰心房利钠肽基线水平

高血压病患者的心血管病事件与主动脉瓣硬化的联系

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世界核心医学期刊文摘（心脏病学分册） 2005年第6期1卷 33-34页

作者： olsen m.h. Wachtell K. Bella J.N 腾增辉

This study investigated whether aortic valve(AV)sclerosis was associated with traditional cardiovascular(CV)risk factors and CV events in hypertensive patients with electrocardiographic left ventricular(LV)hypertrophy, as previously demonstrated in the general population. AV sclerosis was associated with several CV risk factors and predicted CV events independently of prevalent CV disease and traditional CV risk factors, including LV mass and ejection fraction.

关键词：心血管病事件心血管事件血管危险因素射血分数左室肥大左室容积

Free vibration and buckling analysis of polymeric composite beams reinforced by functionally graded bamboo fbers

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Applied mathematics and mechanics(English Edition) 2024年第3期45卷 543-562页

作者： h.m.FEIZABAD m.h.YAS Department of mechanical Engineering Razi UniversityKermanshah ***Iran

Natural fibers have been extensively researched as reinforcement materials in polymers on account of their environmental and economic advantages in comparison with synthetic fibers in the recent *** fibers are renowned for their good mechanical properties,abundance,and short cycle *** beams are one of the fundamental structural components and are susceptible to mechanical loads in engineering applications,this paper performs a study on the free vibration and buckling responses of bamboo fiber reinforced composite(BFRC)beams on the elastic *** different functionally graded(FG)layouts and a uniform one are the considered distributions for unidirectional long bamboo fibers across the *** elastic properties of the composite are determined with the law of *** hamilton’s principle,the governing equations of motion are *** generalized differential quadrature method(GDQm)is then applied to the equations to obtain the *** achieved outcomes exhibit that the natural frequency and buckling load values vary as the fiber volume fractions and distributions,elastic foundation stiffness values,and boundary conditions(BCs)and slenderness ratio of the beam ***,a comparative study is conducted between the derived analysis outcomes for BFRC and homogenous polymer beams to examine the effectiveness of bamboo fibers as reinforcement materials,demonstrating the significant enhancements in both vibration and buckling responses,with the exception of natural frequencies for cantilever beams on the Pasternak foundation with the FG-◇fiber ***,the obtained analysis results of BFRC beams are also compared with those for carbon nanotube reinforced composite(CNTRC)beams found in the literature,indicating that the buckling loads and natural frequencies of BFRC beams are lower than those of CNTRC beams.

关键词： bamboo fiber free vibration buckling analysis functionally graded(FG)beam elastic foundation generalized differential quadrature method(GDQm)

Novel synthesis of stabilized Bi_(1-x-y)Gd_(x)Dy_(y)O_(1.5) solid electrolytes with enhanced conductivity for intermediate temperature solid oxide fuel cells(SOFCs)

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Journal of Rare Earths 2024年第10期42卷 1903-1911页

作者： Ahmed h.Ibrahim Yehia m.Abbas h.A.Ayoub marwa h.Ali mustafa Aldoori materials Science Laboratory Physics DepartmentFaculty of ScienceSuez Canal University41522IsmailiaEgypt ministry of higher Education and Scientific Research Aliraqia University10011BaghdadIraq

herein,we report the synthesis of a Dy-Gd co-doped cubic phase-stabilized Bi_(2)O_(3) solid electrolyte system via solid-state processing under atmospheric *** with Dy^(3+) and Gd^(3+) has been observed to significantly enhance the densification process during sintering for stabilization purposes,thereby improving the electrical properties of δ-Bi_(2)O_(3)-type *** synthesized ceramics were characterized using X-ray diffraction(XRD),field emission scanning electron microscopy-energy dispersive X-ray spectroscopy(FESEm-EDX),thermal gravimetry/differential thermal analysis(TG/DTA),and the four-point probe technique(4PPT).XRD analysis reveals that the samples Bi_(1-x-y)Gd_(x)Dy_(y)O_(1.5)(y=0.05/x=0.05,0.10,0,15,and 0.20,and x=0.05/y=0.10,0.15,and 0.20) exhibit a stable face-centered cubic δ-phase and a mixed-phase crystallographic *** XRD analysis of the stabilized δ-phase suggests that the prepared oxides show a face-centered cubic(FCC) structure with a space group of *** micrographs reveal that the composition Bi_(0.90)Gd_(0.05)Dy_(0.05)O_(1.5) has no significant ***,an evident increase in the pore formation is observed as the amount of Gd_(2)O_(3) increases until it reaches 20%.This finding suggests that dense pellets are formed during the sintering process at 900-1000℃.The DTA analyses were performed to verify the phase stability,which agrees with the XRD *** electrochemical performance of the synthesized Dy-Gd co-doped Bi_(2)O_(3)solid electrolyte system was evaluated and analyzed in detail by using the electrochemical impedance spectroscopy(EIS) technique,Based on EIS and conductivity measurements,Bi_(0.75)Gd_(0.20)Dy_(0.05)O_(1.5) exhibits the lowest activation energy of 0.519 eV and the highest conductivity value of 0.398 S/cm at 627℃compared to the other samples;this composition can be used as a solid electrolyte for intermediatetemperature solid oxide fuel cells(SOFCs).

关键词： Solid oxide fuel cells(SOFCs) Rare earths Solid-state processing Rietveld Fast Fourier transform(FFT) Electrochemical impedance spectroscopy(EIS)

Influence of erbium on structural,and charged particles,photons,and neutrons shielding properties of Ba_(1-x)Er_(x)SnO_(3) perovskite ceramics

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Journal of Rare Earths 2024年第4期42卷 724-732页

作者： m.K.h.hamad Nidal Dwaikat m.h.A.mhareb m.I.Sayyed R.m.h.mad Y.S.m.Alajerami m.A.Almessiere Gameel Saleh Ahmad hussein Alomari K.A.Ziq Department of Basic Sciences School of Social and Basics SciencesAl Hussein Technical UniversityKing Abdullah II St 242Amman11831Jordan Department of Physics College of Engineering and PhysicsInterdisciplinary Research Center for Advanced MaterialsKing Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Department of Physics College of ScienceImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Basic and Applied Scientific Research Center Imam Abdulrahman Bin Faisal UniversityP0.Box 1982Dammam31441Saudi Arabia Department of Physics Faculty of ScienceIsra UniversityAmman11622Jordan Department of Nuclear medicine Research Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Arabia medical Imaging Department Applied Medical Sciences FacultyAl Azhar University-Gaza CityPo.Box 1277Palestine Department of Biophysics Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box1982Dammam 31441Saudi Arabia Department of Biomedical Engineering College of EngineeringImam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Energy&minerals Regulatory Commission Amman11821Jordan

Five perovskite ceramics samples of Ba_(1-x)Er_(x)SnO_(3) with x=0.00,0.05,0.10,0.15,and 0.20 were synthesized using the conventional solid-state reaction *** prepared samples were characterized by X-ray diffraction(XRD),Fourier transforms infrared(FTIR),and UV-Vis *** shielding properties against ionizing radiation were also *** XRD analysis shows the perovskite cubic structure as the major phase in all *** FTIR reveals a distinctive band around 614-620 cm^(-1) ascribed to the antisymmetric O-Sn-O ***-Vis spectroscopy was used to determine the bandgap according to diffuse reflectance,and the results display a fixed enhancement in the bandgap from 3.2 to 3.3 eV for all ***-ray shielding properties of the synthesized samples were experimentally measured and compared with XCOm computational *** relative differences(Δ,%)between experimental and theo retical values are low and fall within the 0.446%-7.10%*** addition of Er leads to the enhanced density,neutron,and gamma shielding *** contrast,charged particles’shielding parameters gradually reduce with rising Er *** results suggest that Ba_(1-x)Er_(x)SnO_(3) samples can be used in different radiation shielding applications.

关键词： Perovskite Ceramics Gamma ray shielding mass stopping power Rare earths

Effect of cold-working on corrosion induced damage in lug joints

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Defence Technology（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath m.N Chikmath L. murthy h. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

Lug joints are preferred joineries for transferring heavy loads to parent components in aerospace *** experience corrosion due to environmental conditions,improper surface finishes and rubbing displacement between the pin and *** causes damage of different sizes and shapes near the *** degradation due to corrosion-induced damage is modelled as a through-pit at one of the identified critical locations through stress *** effect of this pit on fatigue crack initiation life is ***-hole is pre-stressed by cold-working and the benefits of inducing plastic wake on the intended performance of the lug joint during the damages due to corrosion are brought out and compared with non-cold-worked *** analysis is performed on this lug joint with *** results obtained highlight the benefits of cold-working and the methodology can be extended to damage growth and analyse the effect of surface treatments for better structural integrity of components of aerospace vehicles.

关键词： Lug joint Corrosion Crack initiation Cold-working Structural integrity

The multi-impurity system in CdSe nanoplatelets:electronic structure and thermodynamic properties

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Communications in Theoretical Physics 2024年第3期76卷 165-173页

作者： D A Baghdasaryan V A harutynyan E m Kazaryan h A Sarkisyan Russian-Armenian University H Emin 1230051YerevanArmenia Institute of Applied Problems of Physics 25 Nersisyan St0014YerevanArmenia

This paper theoretically studies the impurity states and the effects of impurity concentration and configuration on the optical,electrical,and statistical properties of CdSe nanoplatelets(NPLs).An image charge-based model of electron-impurity interaction is *** charge-carrier energy spectra and corresponding wave functions depending on the impurity number and configuration are *** electron binding energies are calculated for different NPL *** is shown that the image charge-based interaction potential that arises due to the dielectric constants mismatch is much stronger than the interaction potential that does not take such a mismatch into ***,it is demonstrated that the binding energies are increasing with the number of *** calculate the canonical partition function using the energy levels of the electron,which in turn is used to obtain the mean energy,heat capacity,and entropy of the non-interacting electron *** thermodynamic properties of the non-interacting electron gas that depend on the geometric parameters of the NPL,impurity number,configuration,and temperature are studied.

关键词： nanoplateletes thermodynamic properties impurity states

Impact of carbimazole combined with vitamin E on testicular injury induced by experimental hyperthyroidism in adult albino rats:oxidative/inflammatory/apoptotic pathways

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Asian Journal of Andrology 2024年第4期26卷 396-401页

作者： Ramadan S hussein moustafa m Eyada Rashad m mostafa Sam.h.m Elaidy Shereen h Elsayed hany m Saad Department of Dermatology College of Medicine Prince Sattam Bin Abdulaziz UniversityAl-Kharj 16242Saudi Arabia Department of Dermatology Andrology and STDsAssiut Police HospitalAssiut 71525Egypt Department of Dermatology Venereology and AndrologyFaculty of MedicineSuez Canal UniversityIsmailia 41522Egypt Department of Andrology and Sexology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt Department of Clinical Pharmacology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt Department of Rehabilitation Sciences Faculty of Health and Rehabilitation SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh 12271Saudi Arabia.

Thyroid hormones play essential roles in spermatogenesis,but their effects on infertile males remain poorly *** study aimed to evaluate the impact of combining carbimazole(CBZ)with vitamin E(VE)on testicular injury induced by experimental hyperthyroidism in adult albino rats,focusing on oxidative,inflammatory,and apoptotic *** this experimental study,64 adult male albino Wistar rats were divided into eight groups:Group I(control-untreated),Group II(CBZ-control),Group III(VE-control),Group IV(CBZ+VE-control),Group V(levothyroxine-induced testicular injury),Group VI(levothyroxine+CBZ-treated),Group VII(levothyroxine+VE-treated),and Group VIII(levothyroxine+CBZ+VE-treated).The study was conducted in the Faculty of medicine,Suez Canal University(Ismailia,Egypt).After cervical decapitation,both testes and epididymis were examined histopathologically and *** differences were observed among groups concerning malondialdehyde(mDA),glutathione(GSh),superoxide dismutase(SOD),and catalase(CAT;all Pmerase chain reaction analysis showed significant differences in tumor necrosis factor-α(TNF-α),interleukin-10(IL-10),Bcl-2-associated X protein(BAX),B-cell lym.h.ma 2 protein(Bcl2),p53,Caspase-3,Caspase-8,Caspase-9,and nuclear factor-kappa B(NF-κB)mRNA levels(all Phyperthyroid group treated with CBZ alone(Group VI)exhibited testicular side effects,affecting seminiferous tubules and ***,the Group VIII showed improved spermatogenesis and a decrease in testicular side *** addition of VE to the treatment of hyperthyroid rats with CBZ reduced testicular side effects and seminiferous tubular affection when potentially improving *** research is needed to elucidate the underlying mechanisms fully.

关键词： antithyroid drugs testicular injury thyroid gland vitamin E