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Building the Capacity of Health Professionals in Monitoring and Evaluation in a Public Health Institution: Experience of the National Institute of Public Health (NIPH) of Côte d’Ivoire

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Health 2024年第8期16卷 731-749页

作者： Esme Marie Laure Essis N’guetta Mathilde Manouan Anna-Corine Estell Liema Bissouma Ethmonia Kouamé Ekissi Orsot Tetchi Sagou olivier Yayo Stephane Claon Yao Eugene Konan William Yavo Agbaya Stephane Oga Tenenan Jean Marie Yeo Joseph Aka National Institute of Public Health Abidjan Cte dIvoire Cellule de Recherche en Sant de la Reproduction de Cte dIvoire (CRESAR-CI) Abidjan Cte dIvoire Department of Public Health and Biostatistics UFR of Medical Sciences Felix Houphout Boigny University Abidjan Cte dIvoire Department of Public Health UFR of Pharmaceutical and Biological Sciences Felix Houphout Boigny University Abidjan Cte dIvoire

Background: In the context of the fight against HIV, a lack of skills in monitoring and evaluating the personnel in charge of activities has been identified at the national level. It was the subject of a priority axis of the national plan for monitoring and evaluating the fight against HIV (2006-2010) that was aimed at strengthening the capacities of actors in this area. To increase the critical mass of competent human resources in the short term, the National Institute of Public Health (NIPH) of Côte d’Ivoire organized monitoring and evaluation training sessions for healthcare professionals from 2011 to 2016. Methods: A single case study with multiple levels of analysis was carried out, combining a qualitative survey and a literature review. An evaluation was carried out six months after each training session. In addition, the results of the pre- and post-tests and of the daily and final evaluations that accompanied the various training sessions were used to provide further information. The qualitative data collected were analyzed using INVIVO 15 software. Results: Some 89 health professionals (69% men and 31% women) working at the national level (51% at the central level, including 58% in health programs) and in development partner agencies (37%) participated in this capacity building program. Most participants were senior health managers (56%), data managers (23%), and statisticians and computer scientists (10%). Almost all the trainings were financed by 16 technical and financial partners (85%), mainly the MEASURE Evaluation project (27%). Conclusion: M&E training, despite all its imperfections, has made it possible to identify M&E training needs at the national level and to increase the critical mass of national skills and to have some culture in M&E.

关键词： Short-Term Training Capacity Building Monitoring and Evaluation Health Professional Africa Côte d’Ivoire

Laparoscopic liver resection for living donation: Where do we stand?

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World Journal of Gastroenterology 2014年第42期20卷 15590-15598页

作者： Fran?ois Cauchy Lilian Schwarz olivier Scatton olivier Soubrane Service de Chirurgie Hépato-Bilio-Pancréatique et Transplantation Hépatique H?pital Saint-Antoine Assistance Publique - H?pitaux de Paris Department of HPB Surgery and Liver Transplantation Hopital Beaujon

In Western countries, living donor liver transplantation (LDLT) may represent a valuable alternative to deceased donor liver transplantation. Yet, after an initial peak of enthusiasm, reports of high rates of complications and of fatalities have led to a certain degree of reluctance towards this procedure especially in Western countries. As for living donor kidney transplantation, the laparoscopic approach could improve patient’s tolerance in order to rehabilitate this strategy and reverse the current trend. In this setting however, initial concerns regarding patient’s safety and graft integrity, need for acquiring surgical expertise in both laparoscopic liver surgery and living donor transplantation and lack of evidence supporting the benefits of laparoscopy have delayed the development of this approach. Similarly to what is performed in classical resectional liver surgery, initial experiences of laparoscopy have therefore begun with left lateral sectionectomy, which is performed for adult to child living donation. In this setting, the laparoscopic technique is now well standardized, is associated with decreased donor blood loss and hospital stays and provides graft of similar quality compared to the open approach. On the other hand laparoscopic major right or left hepatectomies for adult-adult LDLT currently lack standardization and various techniques such as the full laparoscopic approach, the hand assisted approach and the hybrid approach have been reported. Hence, even-though several reports highlight the feasibility of these procedures, the true benefits of laparoscopy over laparotomy remain to be fully assessed. This could be achieved through standardization of the procedures and creation of international registries especially in Eastern countries where LDLT keeps on flourishing.

关键词： Liver transplantation Laparoscopy Living donation Postoperative course

Genome Organization and Function： A View from Yeast and Arabidopsis

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Molecular Plant 2010年第4期3卷 678-690页

作者： Julio Saez-Vasquez olivier Gadal LGDP-UMR 5096 CNRS-IRD-Universite de Perpignan via Dornitia 58 Av. Paul Alduy 66860 Perpignan France Laboratoire de Biologie Moleculaire Eucaryote Universite de Toulouse Toulouse France LBME CNRS Toulouse France

Recent progress in understanding higher-order chromatin organization in the nucleus has been considerable. From single gene to chromosome territory, realistic biophysical models can now accurately predict some of the structural feature of cell nuclei. Despite growing evidence of a deterministic nuclear organization, the physiological consequence of spatial genome organization is still unclear. In the simple eukaryotic model, Saccharomyces cerevisiae, clear correlation between gene position and transcription has been established. In this review, we will focus on higher-order chromatin organization in yeast with respect to the nuclear envelope and nucleolus. In Arabidopsis thaliana, a model plant for which we have a complete genome sequence, chromosome territory （CT） arrangement and somatic homologous pairing in interphase nuclei seem to occur randomly. Since chromosomes containing nucleolar organizer regions associate more frequently to form a single nucleolar structure, as in yeast, the nucleolus seems to play a major role in organizing nuclear space. Recent findings have begun to elucidate how plant regulatory factors, such as chromatin remodeling or histone chaperones, affect the chromatin state of ribosomal DNA genes located in two distinct CTarrangements in the nucleus. The functional outcome of yeast nuclear organization allowed us to propose how nuclear organization might contribute to a novel type of epigenetic regulation： the spatial regulation of transcription.

关键词： Nuclear structure chromatin organization nuclear body nucleolus.

Sumixam maximus *** ***.,a New Pennsylvanian Species of Archaeorthoptera(Neoptera;Indiana,USA)

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Acta Geologica Sinica(English Edition) 2011年第3期85卷 515-520页

作者： olivier BTHOUX Christin GROSSMANN Freiberg University of Mining and Technology Institute of GeologyDepartment of PalaeontologyD09596 FreibergGermany Senckenberg Natural History Collections of Dresden Museum of ZoologyD-01109 DresdenGermany Senckenberg Natural History Collections of Dresden Museum of Zoology D-01109 DresdenGermany

A new Mazon-Creek-type fossil specimen is described as Sumixam maximus *** ***., assigned to the taxon Archaeorthoptera Bethoux and Nel,2002(composed of Orthoptera and some fossil relatives):it exhibits one of the diagnostic character states of this taxon,which is the fusion of CuA(emerging from M+CuA)with CuP,or a branch of it.A more precise taxonomic assignment is out of *** new taxon exhibits a fusion of the anterior branch of MA with RP,and a point of divergence of MA and MP located near the point of divergence of CuA(from M + CuA),but lack a branching of *** unique combination of character states is probably derived with respect to a number of contemporaneous *** maximus *** *** most likely the closest known relative of the panorthopterans,which include all the recent Archaeorthoptera.

关键词： Insecta Upper Carboniferous Mazon Creek

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库夫施泰因在童话世界和无垠山野共振

环球人文地理 2024年第11期 144-152页

作者：十一 ARochau Erika Karl Allen Lugmayer Nikolai Sorokin olivier pictureserver Roman Babakin Stephan Sühling Thomas Gross 摄图网

欧洲最适合隐居的地方在哪里？近日Lonely Planet公布的名单中，阿尔卑斯山脚下的库夫施泰因榜上有名。古典音乐环绕小镇，而走进大自然的方式有无数种：夏季徒步，冬季滑雪……库夫施泰因，奥地利西部的一个美丽小镇。得益于德、奥边...

欧洲最适合隐居的地方在哪里？近日Lonely Planet公布的名单中，阿尔卑斯山脚下的库夫施泰因榜上有名。古典音乐环绕小镇，而走进大自然的方式有无数种：夏季徒步，冬季滑雪……库夫施泰因，奥地利西部的一个美丽小镇。得益于德、奥边界的地理之势，无论从慕尼黑还是萨尔茨堡出发，都只需乘车约1小时就能到达。小镇夹在阿尔卑斯山的一个河谷，碧绿草坪、原始森林和清澈湖水环绕四周，八个村庄点缀其间，从高空俯瞰，犹如散落的珍珠。

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AC Impedance Behaviour of Black Diamond Films

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Journal of Materials Science & Technology 2005年第6期21卷 879-882页

作者： olivier GAUDIN Richard B.JACKMAN Electronic and Electrical Engineering University College London Torrington Place London WC1E 7JE UK

The first measurement of impedance on free-standing diamond films from 0.1 Hz to 10 MHz up to 300℃ were reported. A wide range of chemical vapour deposition （CVD） materials were investigated, but here we concentrate on ‘black＇ diamond grown by microwave plasma enhanced CVD （MWPECVD）. The Cole-Cole （Z′ via Z″） plots are well fitted to a RC parallel circuit model and the equivalent resistance and capacitance for the diamond films have been estimated using the Zview curve fitting. The results show only one single semicircle response at each temperature measured. It was found that the resistance decreases from 62 MΩ at room temperature to 4 kΩ at 300℃, with an activation energy around 0.51 eV. The equivalent capacitance is maintained at the level of 100 pF up to 300℃ suggesting that the diamond grain boundaries are dominating the conduction. At 400℃, the impedance at low frequencies shows a linear tail, which can be explained that the AC polarization of diamond/Au interface occurs.

关键词： Black diamond Impedance spectroscopy Activation energy

Three-way Subsynchronous Torsional Interactions Between LCC HVDC,MMC HVDC and a Thermal Generator

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现代电力系统与清洁能源学报(英文) 2023年第4期11卷 1331-1340页

作者： Stefan Kovacevic Dragan Jovcic Pierre Rault olivier Despouys School of Engineering University of AberdeenAberdeen AB243UEU.K. Réseau de Transport d’Électricité ParisFrance

This paper performs a study on three-way subsynchronous torsional interactions(SSTI)between a hybrid dual-infeed high-voltage direct current(HVDC)system and a nuclear *** test case is based on the French IFA2000 line commutated converter(LCC)HVDC(2 GW)and the new Eleclink modular multilevel converter(MMC)HVDC(1 GW)interacting with the Gravelines generator(1 GW).The analysis is performed by the means of the eigenvalue stability assessment on an analytical model,while the accuracy of the conclusions is verified using the detailed non-linear electromegnetic transient program(EMTP)*** study shows that the dual-infeed system may introduce higher risk of the SSTI compared with the point-to-point HVDC *** shows that MMC operating as static synchronous compensator(STATCOM)may further reduce the torsional damping at 6.3 Hz *** conclusion may be unexpected since it is known fact from literature that STATCOM has a beneficial impact on the transient performance of *** studies show that in a sequential HVDC loading,it may be beneficial to load the MMC HVDC ***,the risk of the SSTI may be minimized by changing HVDC controller gains,in particular,by increasing phaselocked-loop(PLL)gains on the LCC rectifier.

关键词： Subsynchronous torsional interaction(SSTI) eigenvalue stability hybrid dual-infeed high-voltage direct current(HVDC) line commutated converter(LCC) modular multilevel converter(MMC) nuclear generator

No touch radiofrequency ablation for hepatocellular carcinoma:a conceptual approach rather than an iron law

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Hepatobiliary Surgery and Nutrition 2022年第1期11卷 132-135页

作者： olivier Seror Unitéde Radiologie Interventionnelle Hôpital AvicenneHôpitaux Universitaires Paris-Seine-Saint-DenisAssistance Publique Hôpitaux de ParisBobignyFrance UnitéMixte de Recherche 1162 Génomique Fonctionnelle des Tumeurs SolidesInstitut National de la Santéet de la Recherche MédicaleParis 7ParisFrance Unitéde Formation et de Recherche SantéMédecine et Biologie Humaine UniversitéParis 13Communautéd’Universités et Etablissements Sorbonne Paris CitéBobignyFrance

Using conventional intra-tumoral radiofrequency ablation(IT-RFA)for the treatment of hepatocellular carcinoma(HCC)3 cm or smaller,high local tumor recurrence rates have been reported(up to 20%)despite initial complete ablation rates reaching 95%.This prompted the recommendation of no touch RFA(NT-RFA)for this indication in clinical practice since 2006(1).The rationale of NT-RFA is based on the assumption that the insertion of electrodes no longer inside but deliberately just outside the borders of the tumors could allow achieving more consistent tumoral ablation with safety margins,hence preventing further secondary local progression from unablated extranodular peripheral microscopic tumoral foci(2).

关键词： prompt ablation hence

Ab initio simulation of the sum-frequency generation response of optically active liquids in the presence of a dc electric field —determination of the absolute molecular configuration

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Science China Chemistry 2014年第10期57卷 1405-1408页

作者： CHAMPAGNE Benot QUINET olivier Laboratoire de Chimie Théorique Unité de Chimie Physique Théorique et Structurale Université de Namur

Quantum chemical computations have been performed to evaluate the first and second hyperpolarizability quantities of the interference term, linear in the external static electric field, that appear in the electric field-induced sum-frequency generation signal of chiral liquids. These are performed at the time-dependent Hartree-Fock level on the prototypical 1,1′-bi-2-naphtol chiral species.

关键词： second and third hyperpolarizabilities chirality nonlinear optics time-dependent Hartree-Fock