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On Unsupervised Training of Multi-Class Regularized Least-Squares Classifiers

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Journal of Computer Science & Technology 2014年第1期29卷 90-104页

作者： Tapio pahikkala Antti Airola Fabian Gieseke oliver Kramer ACM IEEE Department of Information Technology University of Turku Department of Computer Science University of Copenhagen Computer Science Department Carl von Ossietzky University of Oldenburg

In this work we present the first efficient algorithm for unsupervised training of multi-class regularized least- squares classifiers. The approach is closely related to the unsupervised extension of the support vector machine classifier known as maximum margin clustering, which recently has received considerable attention, though mostly considering the binary classification case. We present a combinatorial search scheme that combines steepest descent strategies with powerful meta-heuristics for avoiding bad local optima. The regularized least-squares based formulation of the problem allows us to use matrix algebraic optimization enabling constant time checks for the intermediate candidate solutions during the search. Our experimental evaluation indicates the potential of the novel method and demonstrates its superior clustering performance over a variety of competing methods on real world datasets. Both time complexity analysis and experimental comparisons show that the method can scale well to practical sized problems.

关键词： unsupervised learning multi-class regularized least-squares classification maximum margin clustering combinatorial optimization

Complementary and alternative medicines in irritable bowel syndrome: An integrative view

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World Journal of Gastroenterology 2014年第2期20卷 346-362页

作者： oliver Grundmann Saunjoo L Yoon Department of Medicinal Chemistry College of PharmacyUniversity of FloridaFL 32610United States Department of Adult and Elderly Nursing College of NursingUniversity of FloridaFL 32610United States

Irritable bowel syndrome(IBS)is a common gastrointestinal disorder with a high incidence in the general *** diagnosis of IBS is mainly based on exclusion of other intestinal conditions through the absence of inflammatory markers and specific *** current pharmacological treatment approaches available focus on reducing symptom severity while often limiting quality of life because of significant side *** has led to an effectiveness gap for IBS patients that seek further relief to increase their quality of *** and alternative medicines(CAM)have been associated with a higher degree of symptom management and quality of life in IBS *** the past decade,a number of important clinical trials have shown that specific herbal therapies(peppermint oil and Iberogast?),hypnotherapy,cognitive behavior therapy,acupuncture,and yoga present with improved treatment outcomes in IBS *** propose an integrative approach to treating the diverse symptoms of IBS by combining the benefits of and need for pharmacotherapy with known CAM therapies to provide IBS patients with the best treatment outcome *** steps in this direction are already being considered with an increasing number of practitioners recommending CAM therapies to their patients if pharmacotherapy alone does not alleviate symptoms sufficiently.

关键词： Irritable bowel syndrome Complementary and alternative medicine Hypnotherapy Cognitive behavioral therapy Herbal therapy peppermint

Deep enteroscopy-indications,diagnostic yield and complications

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World Journal of Gastroenterology 2015年第5期21卷 1385-1393页

作者： oliver Moeschler Michael Karl Mueller Department of Gastroenterology Marienhospital OsnabrueckD49074 Osna-brueckGermany

Since its introduction in 2001 capsule endoscopy opened up the small bowel for diagnostic approaches followed by double balloon enteroscopy which enabled the endoscopic community to perform therapeutic interventions in the whole small *** this review the scientific developments related to indications,diagnostic yield and complications of the last years between the competing devices double ballon enteroscopy,single balloon enteroscopy and spiral enteroscopy are illustrated.

关键词： Deep enteroscopy Spiral enteroscopyComplications D

Influence of high- and low-volume liver surgery in gallbladder carcinoma

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World Journal of Gastroenterology 2014年第48期20卷 18445-18451页

作者： Thorsten oliver Goetze Vittorio paolucci Department of Surgery Ketteler-Krankenhaus 63071 Offenbach Germany

AIM: To clarify whether the performance of liver resections (LR) for incidental gallbladder carcinoma (IGBC)’s depends more on the experience of the hospitals in liver surgery than on complying with the guidelines in... 详细信息

关键词： Gallbladder carcinoma Radical cholecystectomy High-volume center German-registry Volume cut-off Hepatobiliary surgery

SCHAUSpIELER,JAGER UND GLADIATOREN:BEMERKUNGEN ZUR"TRUppENBETREUUNG"IN DER KAISERZEITLICHEN ARMEE ROMS

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Journal of Ancient Civilizations 2022年第1期37卷 97-141,144,145页

作者： oliver Stoll Universitat passau

*** und Kultur-getrennte Welten?Quellenzeugnisse wie das Grabepigramm des,Bauern und Soldaten'priscus aus Kaisareia/Hadrianopolis’versetzen so manchen in Staunen:Denn dieser Mann kehrte nach dem ehrenvollen Dienst.

关键词： get Ein des

Confucianism in the perspective of Global Science-A Review of Reconceptualizing Confucian philosophy in the 21st Century

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Frontiers of philosophy in China 2018年第1期13卷 150-163页

作者： oliver Davies School of philosophy Renmin University of China Beijing 100872 China

Today, Confucianism appears as a pre-eminently philosophical approach to the human, which, though deeply rooted in an ancient history in Chinese-speaking lands, now also has the potential to become a global philosophy. In its prescription of a distinctively disciplined way of life, it parallels world religions. However, Confucianism makes no claim to revelation, and so potentially offers a universalist understanding of what it is to be a human being. The fact that the nature or meaning of embodied Confucian life also points to specific social and political structures--even though these may be subject to variation--further suggests that such a universalist anthropology could be one which potentially, though still anchored in philosophy, has concrete content. There are two main challenges to be faced, however. First, there is the need for a reconceptualization of Confucianism in order for it to function as a truly contemporary thought-form. Second, there is the need to discover ways in which the themes and concepts of Confucianism can meaningfully inform our contemporary social and political realities beyond the scope of Chinese language and history. However, these challenges have, in many ways, become less daunting in recent years. Today, there is a new openness for a transcultural, globally-oriented ethical thinking and presence which can foster stability in times of rapid and unpredictable change. And there is a new acceptance that such a practical philosophy, or philosophy of human practice, as a properly global phenomenon could have its origins in China.

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Religion, politics and Ethics： Towards a Global Theorj of Social Transformation

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Frontiers of philosophy in China 2012年第4期7卷 572-597页

作者： oliver Davies School of Arts and Humanities King's College London London WC2R 2LS UK

In this paper＇I set out a phenomenology of social transformation, based on an analysis of the distinctively religious form of communication which underlies the trans-generational and trans-cultural transmission of world traditions, taking Confucianism and Christianity as their representatives. A phenomenological analysis of their communicative structure allows the possibility of a better understanding of what can be learnt from them in the context of contemporary debates in both China and the West on the relations between religion, ethics and politics. This analysis suggests that the ethical consistency of belief and act, which is the necessary condition for the engendering of long-term solidarity in religious community, has significant implications for ethics in politics, and especially for the legitimacy of representational leadership as a focal point for change in society. The paper concludes that the historical experience of world religions can offer new insights into the nature of political leadership and representation in today＇s globalised world and that the appropriate locus for this inquiry is the present negotiation and re-negotiation of relations between China and the West.

关键词： social transformation Confucianism and Christianity phenomenology,leadership

The visual analytics of big,open public transport data-a framework and pipeline for monitoring system performance in Greater Sydney

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Big Earth Data 2021年第1期5卷 134-159页

作者： oliver Lock Tomasz Bednarz Christopher pettit City Analytics Lab Faculty of Built EnvironmentUniversity of New South WalesSydneyAustralia Expanded perception and Interaction Centre Faculty of Art&DesignUniversity of New South WalesSydneyAustralia

Many cities,countries and transport operators around the world are striving to design intelligent transport *** systems capture the value of multisource and multiform data related to the functionality and use of transportation infrastructure to better support human mobility,interests,economic activity and *** aim to provide services that can enable transportation customers and managers to be better informed and make safer and more efficient use of *** developing principles,guidelines,methods and tools to enable synergistic work between humans and computer-generated information,the science of visual analytics continues to expand our understanding of data through effective and interactive visual *** this paper,we describe an application of visual analytics related to the study of movement and transportation *** application documents the use of rapid,2D and 3D web visualisation and data analytics libraries and explores their potential added value to the analysis of big public transport performance data.A novel approach to displaying such data through a generalisable framework visualisation system is *** framework recalls over a year’sworth of public transport performance data at a highly granular level in a fast,interactive browser-based *** Sydney,Australia forms a case study to highlight potential uses of the visualisation of such large,passively-collected data sets as an applied research *** this paper,we argue that such highly visual systems can add data-driven rigour to service planning and longer-term transport ***,they enable the sharing of quality of service statistics with various stakeholders and citizens and can showcase improvements in services before and after policy *** paper concludes by making recommendations on the value of this approach in embedding these or similar web-based systems in transport planning practice,performance

关键词： WebGL visual analytics public transportation transport performance visualisation open data big data

Neutrophils in chronic inflammatory diseases

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Cellular & Molecular Immunology 2022年第2期19卷 177-191页

作者： Andrea Herrero-Cervera oliver Soehnlein Ellinor Kenne Institute for Experimental pathology Center for Molecular Biology of InflammationWestfälische Wilhelms-Universität MünsterMünsterGermany Department of physiology and pharmacology Karolinska InstitutetStockholmSweden.

Chronic inflammation is a component of many disease conditions that affect a large group of individuals *** inflammation is characterized by persistent,low-grade inflammation and is increased in the aging *** are normally the first responders to acute inflammation and contribute to the resolution of ***,in chronic inflammation,the role of neutrophils is less well understood and has been described as either beneficial or detrimental,causing tissue damage and enhancing the immune *** evidence suggests that neutrophils are important players in several chronic diseases,such as atherosclerosis,diabetes mellitus,nonalcoholic fatty liver disease and autoimmune *** review will highlight the interaction of neutrophils with other cells in the context of chronic inflammation,the contribution of neutrophils to selected chronic inflammatory diseases,and possible future therapeutic strategies.

关键词： Chronic Inflammation Disease Neutrophil Neutrophil extracellular traps