检索结果-南通市图书馆

Thyroid Nodule: Alpha Score 2.0 Classification for FNAB Selection, Multicentric Study in Latin America

Open Journal of Radiology 2021年第4期11卷 160-174页

作者： Glenn Mena Maria Cristina Chammas Carlos Mario Gonzalez Vasquez Lylian Rocío Villagómez Marco Alfredo Muñoz Pico Patricio Alejandro Montalvo Santiago Mena-Bucheli Julio Olmedo Elizabeth Quintero Pedro Henrique de Marqui Moraes Osmar Cassio Saito Hubertino Diaz Denise Romero Gabriela Velalcazar Angel Ramón Sosa Fleitas Yamil oliver Quevedo Ontaneda Victor Ricardo Chara Alpha Imagen Radiología e Intervencionismo Quito Ecuador Hospital das Clínicas Faculdade de Medicina da Universidade de Sã o Paulo S&#227 o Paulo Brasil Hospital Pablo Tobón Uribe Medellin Colombia Hospital del Instituto Ecuatoriano de Seguridad Social Quito Sur Quito Ecuador Hospital San Francisco de Quito Quito Ecuador Hospital Edgardo Rebagliati Martins Lima Perú Hospital Carlos Andrade Marín Quito Ecuador Hospital de Clínicas San José de San Martín Buenos Aires Argentina Hospital Universitario de Los Andes Mérida Venezuela Hospital de la Policía Quito Ecuador Hospital Sisol Tacna Perú

Introduction: To perform a Latin-American multicentric study for the prediction of benign and malignant thyroid nodules using Alpha Score, and to compare it with ACR TIRADS® and Bethesda®. Materials and Methods: A prospective multicentric study in 10 radiological hospitals and institutions of Latin America was performed and 818 thyroid nodules were analyzed by ultrasound and classified by using both ACR TIRADS® and Alpha Score;fine-needle aspiration biopsy was performed when needed and classified with Bethesda. The relationships between predictors were analyzed by using binary logistic regression, statistical significance was defined by a p-value of 0.05, with an error margin of 4% and 95% confidence intervals. Results: Alpha Score 2.0 establishes five types of malignant predictors: microcalcifications, irregular borders, taller-than-wide shape, predominant solid texture and hypoechogenicity;a diameter equal to or greater than 1.5 cm adds an extra point to the final score. Resulting classification divides TNs into 4 categories: benign (1.9%), low suspicion (8.7%), mild suspicion (13.6%) and high suspicion (75.7%) of malignancy probability;sensitivity of 82%, specificity of 74%, the positive predictive value of 94%, the negative predictive value of 51%, the statistical accuracy of 81%, odds ratio of 108.89 and correlation with ACR TIRADS of 0.77 and Bethesda of 0.91. Conclusions: Alpha Score 2.0 has superior diagnostic accuracy and performance compared to the previously published Alpha Score and is able to classify a benign TN in a precise, safe and accurate way, avoiding unnecessary FNABs or determining the necessity of FNAB in cases of moderate to high suspicion of malignancy.

关键词： Thyroid Cancer-Clinical Radiology-Imaging Thyroid Nodule Alpha Score TIRADS® Thyroid Ultrasonography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

下一代CMOS纳米线:从原子级到电路级仿真

引用

中国集成电路 2021年第9期30卷 37-41页

作者： Udita Kapoor Sean CKelly Mark Townsend Derek Kimpton Eric Guichard 欧阳文捷 Sebastien Martini Thierry Poiroux oliver Rozeau James Charles Daniel Lemus Tillmann Kubis 美国Silvaco公司法国CEA-Leti研究所美国普渡大学

本文介绍了一个基于纳米线的环形振荡器电路的完整仿真流程,其中的有源器件运用了原子级器件模拟器对其进行了仿真。该仿真的结果已被证明适合于专门为纳米线/GAA环栅场效应晶体管(FET)制定的有源器件SPICE紧凑模型。最后,本文中把有源... 详细信息

本文介绍了一个基于纳米线的环形振荡器电路的完整仿真流程,其中的有源器件运用了原子级器件模拟器对其进行了仿真。该仿真的结果已被证明适合于专门为纳米线/GAA环栅场效应晶体管(FET)制定的有源器件SPICE紧凑模型。最后,本文中把有源器件纳入SPICE网表,其中包括了后端电阻和电容寄生电阻。

关键词： TCAD仿真原子器件仿真 SPICE仿真硅纳米线FET

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Current status and trends in forest genomics

引用

Forestry Research 2022年第1期2卷 99-120页

作者： Dulal Borthakur Victor Busov Xuan Hieu Cao Qingzhang Du oliver Gailing Fikret Isik Jae-Heung Ko Chenghao Li Quanzi Li Shihui Niu Guanzheng Qu Thi Ha Giang Vu Xiao-Ru Wang Zhigang Wei Lin Zhang Hairong Wei Department of Molecular Biosciences and Bioengineering University of Hawaii at Manoa1955 East-West RoadHonoluluHI 96822USA College of Forest Resources and Environmental Science Michigan Technological UniversityHoughtonMI 49931USA Forest Genetics and Forest Tree Breeding Faculty for Forest Sciences and Forest EcologyUniversity of GöttingenBüsgenweg 237077 GöttingenGermany National Engineering Research Center of Tree Breeding and Ecological Restoration College of Biological Sciences and TechnologyBeijing Forestry UniversityBeijing 100083P.R.China Cooperative Tree Improvement Program North Carolina State UniversityRaleighNC 27695USA Department of Plant&Environmental New Resources Kyung Hee University1732 Deogyeong-daeroYongin 17104Republic of Korea State Key Laboratory of Tree Genetics and Breeding Northeast Forestry UniversityHarbin 150040P.R.China State Key Laboratory of Tree Genetics and Breeding Chinese Academy of ForestryBeijing 100093P.R.China Department of Ecology and Environmental Science UmeåPlant Science CentreUmeåUniversityUmeå90187Sweden College of Life Sciences Heilongjiang UniversityHarbin 150080P.R.China Key Laboratory of Cultivation and Protection for Non-Wood Forest Trees Ministry of EducationCentral South University of Forestry and TechnologyChangsha 410004Hunan ProvinceP.R.China

Forests are not only the most predominant of the Earth's terrestrial ecosystems,but are also the core supply for essential products for human ***,global climate change and ongoing population explosion severely threatens the health of the forest ecosystem and aggravtes the deforestation and forest *** genomics has great potential of increasing forest productivity and adaptation to the changing *** the last two decades,the field of forest genomics has advanced quickly owing to the advent of multiple high-throughput sequencing technologies,single cell RNA-seq,clustered regularly interspaced short palindromic repeats(CRISPR)-mediated genome editing,and spatial transcriptomes,as well as bioinformatics analysis technologies,which have led to the generation of multidimensional,multilayered,and spatiotemporal gene expression *** technologies,together with basic technologies routinely used in plant biotechnology,enable us to tackle many important or unique issues in forest biology,and provide a panoramic view and an integrative elucidation of molecular regulatory mechanisms underlying phenotypic changes and *** this review,we recapitulated the advancement and current status of 12 research branches of forest genomics,and then provided future research directions and focuses for each ***,a shift from simple biotechnology-based research to advanced and integrative genomics research,and a setup for investigation and interpretation of many spatiotemporal development and differentiation issues in forest genomics have just begun to emerge.

关键词： forest routine biotechnology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

商业模式创新设计大全

引用

作者： (瑞士)奥利弗·加斯曼(oliver Gassmann) (瑞士)卡洛琳·弗兰肯伯格(Karolin Frankenberger) (瑞士)米凯拉·奇克(Michaela Csik)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

千号馆豪华公寓

引用

当代建筑 2020年第5期 50-59页

作者：扎哈·哈迪德帕特里克·舒马赫 Alessio Costantino Martin Pfleger oliver Bray Theodor Wender Irena Predalic Celina Auterio Carlota Boyer Hufton+Crow 扎哈·哈迪德建筑师事务所

项目名称:千号馆豪华公寓业主:1000 Biscayne Touer, LLC建设地点:美国迈阿密海滩设计单位:扎哈·哈迪德建筑师事务所合作单位:O'Donnell Dannwolf Partners用地面积:1.27 hm2建筑层数:62竞赛团队:Sam Saffarian,Eva Tiedemann,Brandon Gehrke,Cynthia Du,Grace Chung,Aurora Santana,Olga Yatsyuk结构专业:De Simone Consulting Engineers景观设计:Enea Garden Design消防设计:SLS Consulting Inc风洞顾问:RWDI Consulting Engineers&Scientists设计时间:2012～2020年建成时间:2020年图纸版权:扎哈·哈迪德建筑师事务所

关键词：

来源：

维普期刊数据库

同方期刊数据库评论