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Magnetic compression anastomosis to restore biliary tract continuity after obstruction following major abdominal trauma:A case report

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World journal of Gastrointestinal Surgery 2024年第6期16卷 1933-1938页

作者： Miao-Miao Zhang jie Tao Huan-Chen Sha Yun Li Xiao-Gang Song oliver j muensterer Fang-Fang Dong Li Zhang Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Shaanxi Provincial Key Laboratory of Magnetic Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina National Local joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Pediatric Surgery Dr.von Hauner Children’s HospitalLudwig-Maximilians-University Medical CenterMunich 80337Germany

BACKGROUND The combination of magnetic compression anastomosis(MCA)and endoscopy has been used to treat biliary stricture after liver ***,its use for the treatment of complex biliary obstruction after major abdominal trauma has not been *** case report describes the successful use of MCA for the treatment of biliary obstruction resulting from major abdominal trauma.A 23-year-old man underwent major abdominal surgery(repair of liver rupture,right half colon resection,and ileostomy)following a car accident one year *** abdominal drainage tube,positioned at the Winslow foramen,was draining approximately 600-800 mL of bile per *** the two endoscopic retrograde cholangiopancreatography procedures,the guide wire was unable to enter the common bile duct,which prevented placement of a biliary *** combined with endoscopy was used to successfully achieve magnetic anastomosis of the peritoneal sinus tract and duodenum,and then a choledochoduodenal stent was ***,the external biliary drainage tube was *** patient achieved internal biliary drainage leading to the removal of the external biliary drainage tube,which improved the quality of *** Magnetic compression technique can be used for the treatment of complex biliary obstruction with minimal operative trauma.

关键词： Magnetic compression anastomosis Magnetosurgery Endoscopy Magnetic Surgery Clinic Biliary obstruction Case report

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Single-incision pediatric endosurgery in newborns and infants

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World journal of Clinical Pediatrics 2015年第4期4卷 55-65页

作者： Yury Kozlov Vladimir Novozhilov Polina Baradieva Pavel Krasnov Konstantin Kovalkov oliver j muensterer Department of Neonatal Surgery Pediatric Hospital Irkutsk State Medical University Irkutsk State Medical Academy of Continuing Education Irkutsk Pediatric Hospital Kemerovo Pediatric Surgery University Medicine of the Johannes Gutenberg University

This study focuses on the successful application of single-incision pediatric endosurgery in the treatment of congenital anomalies and acquired diseases in neonates and infants. The purpose of this scientific review consists in highlighting the spectrum, indications, applicability, and effectiveness of single-port endosurgery in children during the first 3 postnatal months.

关键词： Laparoscopy Neonates Infants Singleincision laparoscopic surgery Single-incision pediatric endosurgery

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ON KARUSH-KUHN-TUCKER POINTS FOR A SMOOTHING METHOD IN SEMI-INFINITE OPTIMIZATION

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journal of Computational Mathematics 2006年第6期24卷 719-732页

作者： oliver Stein Department o.f Mathematics-C RWTH Aachen University Germany

We study the smoothing method for the solution of generalized semi-infinite optimization problems from （O. Stein, G. Still： Solving semi-infinite optimization problems with interior point techniques, SIAM j. Control Optim., 42（2003）, pp. 769-788）. It is shown that Karush-Kuhn-Tucker points of the smoothed problems do not necessarily converge to a Karush-Kuhn-Tucker point of the original problem, as could be expected from results in （F. Facchinei, H. jiang, L. Qi： A smoothing method for mathematical programs with equilibrium constraints, Math. Program., 85（1999）, pp. 107-134）. Instead, they might merely converge to a Fritz john point. We give, however, different additional assumptions which guarantee convergence to Karush-Kuhn：Tucker points.

关键词： Generalized semi-infinite optimization Stackelberg game Constraint qualifi-cation Smoothing NCP function.

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Special Topic:Food Chemistry

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journal of Analysis and Testing 2018年第2期2卷 107-108页

作者： oliver j.Schmitz Applied Analytical Chemistry University of Duisburg-EssenUniversitaetsstr.545141 EssenGermany

The quality of food is of utmost importance to a society and harmful contaminants,e.g.,the Minamata disease is a chronic poisoning by organic mercury compounds that first appeared in the mid-1950s around the city of *... 详细信息

关键词： mercury poisoning thousand

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A New Concept for Regulatory Water Monitoring Via High-Performance Liquid Chromatography Coupled to High-Resolution Mass Spectrometry

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journal of Analysis and Testing 2018年第4期2卷 342-351页

作者： Susanne Brüggen oliver j.Schmitz North Rhine Westphalian State Agency for Nature Environment and Consumer ProtectionLANUVDuesseldorfGermany Applied Analytical Chemistry Faculty of ChemistryUniversity of Duisburg-EssenEssenGermany Teaching and Research Center for Separation University of Duisburg-EssenEssenGermany

A combined approach of target,suspected target and non-target screening using liquid chromatography-high-resolution mass spectrometry(LC-HRMS)was used to develop a new concept for water *** the current LC-MS/MS target approach for water monitoring,all targets can be quantified,but no additional information about the sample is *** the new concept,it is possible to detect 97%of the target compounds with a simplified quantification method without losing ***,a suspect target screening can be performed to get broader qualitative information about the water *** addition,the non-target screening offers the possibility to identify unknown *** three evaluation steps depend on the same analytical measurement so that a lot of measurement and quality assurance effort can be *** concept could change water monitoring and assessment,and make it much more efficiently without losing *** is a chance to measure less but learn more about the water bodies.

关键词： New concept for regulatory water monitoring High-resolution mass spectrometry(HRMS) Suspected target analysis Non-target analysis

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Lysozyme as an alternative to growth promoting antibiotics in swine production

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journal of Animal Science and Biotechnology 2016年第1期7卷 34-40页

作者： W. T. oliver j.E.Wells USDA ARS U.S. Meat Animal Research Center P. O. Box 166 Clay Center NE68933-0166 USA

Lysozyme is a naturally occurring enzyme found in bodily secretions such as tears, saliva, and milk. It functions as an antimicrobial agent by cleaving the peptidoglycan component of bacterial cell walls, which leads to cell death. Antibiotics are also antimicrobials and have been fed at subtherapeutic levels to swine as growth promoters. These compounds benefit swine producers by minimizing production losses by increasing feed efficiency and decreasing susceptibility to bacterial infection and disease. This manuscript reviews the knowledge of the effects of lysozyme, as compared to traditional subtherapeutic antibiotics in swine feed, on pig performance and health. It is clear from decades of studies that antibiotic use in feeds increases pig performance, particularly in the nursery. Similarly, lysozyme, as a feed additive, increases growth and feed efficiency. While the mechanism by which antibiotics and lysozyme improve performance is not clearly understood, both of these feed additives improve gastrointestinal health, improve the metabolic profile, and alter the gastrointestinal bacteria ecology of swine. Therefore, lysozyme is a suitable alternative to growth-promoting subtherapeutic antibiotic use in swine feed.

关键词： Antibiotics Gastrointestinal Lysozyme Microbiota Review Swine

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Optical prediction of single muscle fiber force production using a combined biomechatronics and second harmonic generation imaging approach

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Light(Science & Applications) 2018年第1期7卷 289-302页

作者： Dominik Schneidereit Stefanie Nübler Gerhard Prölß Barbara Reischl Sebastian Schürmann oliver j Müller oliver Friedrich Institute of Medical Biotechnology Friedrich-Alexander-University(FAU)Erlangen-NürnbergPaul-Gordan-Str.391052 ErlangenGermany Erlangen Graduate School in Advanced Optical Technologies(SAOT) FAU Erlangen-NürnbergPaul-Gordan-Str.791052 ErlangenGermany Muscle Research Center Erlangen(MURCE) Friedrich-Alexander-University Erlangen-NürnbergErlangenGermany Department of Internal Medicine III University of KielArnold-Heller-Str.324105 KielGermany DZHK(German Center for Cardiovascular Research)Partner Site Hamburg/Kiel/Lübeck KielGermany

Skeletal muscle is an archetypal organ whose structure is tuned to match *** magnitude of order in muscle fibers and myofibrils containing motor protein polymers determines the directed force output of the summed force vectors and,therefore,the muscle’s power performance on the structural *** and function can change dramatically during disease states involving chronic *** remodeling of the cytoarchitecture has been pursued using noninvasive and label-free multiphoton second harmonic generation(SHG)***,structure parameters can be extracted as a measure of myofibrillar order and thus are suggestive of the force output that a remodeled structure can still ***,to date,the parameters have only been an indirect measure,and a precise calibration of optical SHG assessment for an exerted force has been elusive as no technology in existence correlates these *** engineered a novel,automated,high-precision biomechatronics system into a multiphoton microscope allows simultaneous isometric Ca2+-graded force or passive viscoelasticity measurements and SHG *** this MechaMorph system,we studied force and SHG in single EDL muscle fibers from wt and mdx mice;the latter serves as a model for compromised force and abnormal myofibrillar *** present Ca2+-graded isometric force,pCa-force curves,passive viscoelastic parameters and 3D structure in the same fiber for the first ***,we provide a direct calibration of isometric force to morphology,which allows noninvasive prediction of the force output of single fibers from only multiphoton images,suggesting a potential application in the diagnosis of myopathies.

关键词： structure harmonic fibers

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Quantitative Analysis of Bisphenol A in Recycled Paper with a Novel Direct Inlet Probe-Atmospheric Pressure Photoionization–IonTrap-MS

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journal of Analysis and Testing 2017年第3期1卷 255-263页

作者： Simeon Horst oliver j.Schmitz Applied Analytical Chemistry University of Duisburg-EssenUniversitaetsstr.545141 EssenGermany

A new ambient ion source was developed and its application to real samples has been *** ion source is based on a previously build ion source using chemical ionization under atmospheric pressure and extractive electrospray ionization(DIP-APCI/EESI).To enhance the range of analytes,we added to this ion source a photoionization lamp to enable also photoionization,which allows the possibility to analyze polar(EESI),middle(APCI)and non-polar(APPI)analytes with the same source and with no or only a small change of the *** comparison with DIP-APCI,this ion source reaches similar analytical limits but shows better sensitivity for some aromatic and non-polar *** analysis of bisphenol A from extracts of recycled paper demonstrates the use of this ion source for real *** was possible by the use of a deuterated internal standard that was added to the papers before *** atmospheric pressure chemical ionization leads to bad results due to ion suppression,whereas atmospheric pressure photoionization shows results that fit to literature values.

关键词： Ambient ionization Bisphenol A Atmospheric pressure photoionization DIP-APPI Recycled paper

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Effects of vitamin supplementation on inflammatory markers and psychological wellbeing among distressed women:a randomized controlled trial

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journal of Integrative Medicine 2018年第5期16卷 322-328页

作者： j.M.oliver-Baxter H.S.Whitford D.A.Turnbull M.j.Bond School of Psychology The University of Adelaide Sansom Institute for Health Research University of South Australia School of Medicine Flinders University

Background： Multivitamins are a popular supplement taken to promote physical and mental health. During periods of stress, they may have a protective role for health and wellbeing, although the current evidence of their efficacy is mixed. Objective： To determine whether multivitamin supplementation impacts psychological and inflammatory markers of women who are experiencing psychological distress. Design, setting, participants and interventions： An 8-week randomized controlled trial was conducted to assess changes in both psychological state and pro-inflammatory markers of patients receiving multivi- tamins or placebo. The sample comprised women who reported elevated psychological distress in the previous 4 weeks. Main outcome measures： Psychological state was assessed using Spielberger＇s State-Trait Personality Inventory to assess anxiety, curiosity, depression and anger. Pro-inflammatory markers comprised interleukin （IL）-113, IL-5, IL-6, turnout necrosis factor （TNF）-α and TNF-6. Results： Improvements across time were observed for all psychological measures and cytokines, except IL-5, but were independent of the active intervention. Only TNF-β demonstrated a significant differential change between groups over the course of the intervention, in favour of multivitamin supplementation （active group mean rank decreased from 11.1 to 7.1 ; placebo group mean rank decreased from 8.9 to 7.8）. Conclusion： The results suggest that administration of multivitamins was not effective in improving psychological stare. However, some evidence supported the positive impact of multivitamin supplementation on pro-inflammatory cytokine profiles of women currently experiencing stress.

关键词： Psychological stress Cytokines Vitamins Randomized controlled trial

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Design of Agents Interacting with Immunoregulating Proteins:Potential Inhibitors of the Phenylpyruvate Tautomerase Activity Catalysed by Macrophage Migration Inhibitory Factor (MIF)

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Chinese journal of Chemistry 2003年第10期21卷 1256-1262页

作者： CARPY Alain j.M. HAASBROEK P.P. oliver D.W. PTC-UMR 5472 CNRS Department of Pharmacy and PharmacologyPharmacology Faculty of Health Science University of Bordeaux ITalence France University of Witwatersrand JohannesburgSouth AfricaPotchefstroom University for CHE PotchefstroomSouth Africa

The macrophage migration inhibitory factor has been implicated in a number ofimmune and inflammatory processes. MIF presents particular opportunities for drug design anddevelopment with potential therapeutic applications. Drug design strategies taking intoconsideration of specific stereochemical and tautomeric requirements in the interaction of MIF withsubstrates and inhibitors allow several novel structures to be designed. Our investigationssuccessfully explored the tautomeric and stereochemical aspects of new compounds of the2-phenylpyruvic acid type, both experimentally, through synthesis and structural investigations andcomputationally, through molecular mechanics and quantum mechanics calculations.

关键词： macrophage migration inhibitory factor phenylpyru-vate tautomerase activity azlactone phenylpyruvic acid derivative

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