检索结果-南通市图书馆

Mindf.lness training in medical education as a means to improve resilience,empathy,and mental health in the medical prof.ssion

引用

World Journal of.Psychiatry 2024年第4期14卷 489-493页

作者： Edison Iglesias de oliveira Vidal Luiz f.rnando Alvarenga Ribeiro Marco Antonio de Carvalho-f.lho f.rnanda Bono f.kushima Internal Medicine Department Botucatu Medical SchoolSao Paulo State University(UNESP)Botucatu 18618-687SPBrazil Wenckebach Institute f.r Education and Training LEARN-Lifelong LearningEducation and Assessment Research NetworkUniversity Medical Center GroningenGroningen 9713AVGroningenNetherlands Assertiva Mindf.lness Botucatu 18603-970SPBrazil Surgical Specialties and Anesthesiology Department Botucatu Medical SchoolSão Paulo State University(UNESP)Botucatu 18618-687SPBrazil

The high rates of.depression,burnout,and increased risk of.suicide among medical students,residents,and physicians in comparison with other careers signal a mental health crisis within our *** contend that this crisis coupled with the inadequate acquisition of.interpersonal skills during medical education results f.om the interaction between a challenging environment and the mental capital of.***,we posit that mindf.lness-based practices are instrumental f.r the development of.major components of.mental capital,such as resilience,f.exibility of.mind,and learning skills,while also serving as a pathway to enhance empathy,compassion,self.awareness,conf.ict resolution,and relational ***,the evidence base supporting the ef.ectiveness of.mindf.lness-based interventions has been increasing over the years,and a growing number of.medical schools have already integrated mindf.lness into their *** we acknowledge that mindf.lness is not a panacea f.r all educational and mental health problems in this f.eld,we argue that there is currently an unprecedented opportunity to gather momentum,spread and study mindf.lness-based programs in medical schools around the world as a way to address some longstanding shortcomings of.the medical prof.ssion and the health and educational systems upon which it is rooted.

关键词： Mindf.lness Medical education Mental capital Mental health Medical students Resilience

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An unexpected cellular f.untain of.youth:platelets provide f.ctors rejuvenating brain f.nctions

引用

Signal Transduction and Targeted Therapy 2024年第1期9卷 16-18页

作者： Harald f.Langer Department of.Cardiology AngiologyHaemostaseology and Medical Intensive CareUniversity Medical Centre MannheimMedical Faculty MannheimHeidelberg UniversityMannheimGermany German Centre f.r Cardiovascular Research(DZHK) Partner Site Heidelberg/MannheimMannheimGermany European Center f.r Angioscience Medical Faculty MannheimHeidelberg UniversityMannheimGermany Cardiovascular systems biology Medical Clinic IUniversity Heart Center LübeckLübeckGermany

In a recent manuscript published in Nature,Schroer et *** that platelets and in particular platelet derived Pf.4(CXCL4)are a novel f.ctor,which can rejuvenate the mammalian neuronal system.1 These f.ndings have the potential to trigger an entire new f.eld of.research opening new platelet-derived candidate ef.ector molecules f.r supporting regeneration.

关键词： supporting platelets f.nding

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chlorogenic acid ameliorates heart f.ilure by attenuating cardiomyocyte f.rroptosis

引用

Journal of.Traditional Chinese Medical Sciences 2024年第2期11卷 191-198页

作者： Huang K. Li f. Tang J. Pu H. Sukhorukov V. Orekhov A.N. Guo S. School of.Traditional Chinese Medicine Beijing University of Chinese Medicine Beijing 102488 China Laboratory of.Angiopathology Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences Moscow 125315 Russian Federation

Objective: To elucidate the ef.ects of.chlorogenic acid (CGA), a bioactive polyphenol compound prevalent in traditional Chinese medicine and various f.ods, including Lonicera japonica Thunb. (Jin Yin Hua), Eucommia ulmoides Oliv. (Du Zhong Ye), tea, and cof.ee, on cardiomyocyte f.rroptosis and heart f.ilure. Methods: We assessed the ef.ect of.CGA on cardiac f.nction using a mouse model of.heart f.ilure induced by transverse aortic constriction (TAC). These indicators included the lef. ventricular ejection f.action (LVEf., f.actional shortening (LVf.), end-systolic volume (LVESV), end-diastolic volume (LVEDV), end-systolic diameter (LVESD), and end-diastolic diameter (LVEDD). An isoprenaline hydrochloride (ISO)-induced H9c2 cardiomyocyte cell model was also established, and the cells were treated with various concentrations of.CGA. To assess the ef.ect of.CGA on f.rroptosis in cardiomyocytes, we measured cell viability and evaluated the levels of.intracellular reactive oxygen species (ROS), f.rrous ions (f.2+), and lipid peroxidation using f.uorescent staining. To clarif. the f.rroptosis signaling pathway regulated by CGA, western blotting was used to examine the expression of.f.rroptosis biomarkers, specif.cally solute carrier f.mily 7 member 11 (SLC7A11) and glutathione peroxidase 4 (GPX4), in H9c2 cardiomyocytes and mouse myocardial tissues. Results: CGA signif.cantly enhanced cardiac perf.rmance indices such as LVEf. LVf., LVESV, LVEDV, LVESD, and LVEDD. H9c2 cardiomyocytes exposed to ISO showed decreased cell viability and increased ROS levels, f.2+ content, and lipid peroxidation levels. However, CGA treatment signif.cantly ameliorated these changes. Additionally, in both H9c2 cardiomyocytes and myocardial tissue obtained f.om mice with TAC, CGA increased the expression of.f.rroptosis-related proteins, including SLC7A11 and GPX4. Conclusion: CGA has the potential to enhance cardiac f.nction and diminish lipid peroxidation and ROS levels in cardiomyocytes via th

关键词： Chlorogenic acid f.rroptosis H9c2 cardiomyocyte Heart f.ilure Traditional Chinese medicine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Identity(ies)and Transnationalization of.Brazilian Evangelical Churches in Portugal:Case study of.World Cathedral of.Hope and Victory in Christ Churches

引用

Cultural and Religious Studies 2024年第3期12卷 133-145页

作者： Jonas Pereira de oliveira Júnior University of.Porto PortoPortugal

The presence of.evangelicals in Brazil is a social and religious phenomenon that has aroused interest of.many scholars due to its rapid and signif.cant expansion in recent decades and its projection beyond national *** evangelical denominations that stand out in this scenario are Pentecostal churches,which have developed intense missionary activity in several countries,including *** this article,we intend to analyze f.atures and challenges of.Brazilian evangelical churches:World Cathedral of.Hope(CIME)(Catedral Mundial da Esperança-ICME)and Assembly of.God Victory in Christ(ADVEC)(Assembleia de Deus Vitória em Cristo-ADVEC)that operate in Portugal,seeking to understand issues of.identity and belonging of.these communities,their models of.transnationalization,its evangelization strategies and its adaptations to Portuguese context,in the period f.om 2000 to 2020.

关键词： identity transnationalization secularization Brazilian migration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The viscous strip approach to simplif. the calculation of.the surf.ce acoustic wave generated streaming

引用

Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 711-724页

作者： f.JAZINI DORCHEH M.GHASSEMI f.el Cells and Nano Systems(f.NS)Laboratory Department of Mechanical EngineeringK.N.Toosi University of TechnologyTehran 19697Iran

In recent decades,the importance of.surf.ce acoustic waves,as a biocompatible tool to integrate with microf.uidics,has been proven in various medical and biological *** numerical modeling of.acoustic streaming caused by surf.ce acoustic waves in microchannels requires the ef.ect of.viscosity to be considered in the equations which complicates the *** this paper,it is shown that the major contribution of.viscosity and the horizontal component of.actuation is concentrated in a narrow region alongside the actuation *** the inviscid equations are considerably easier to solve,a division into the viscous and inviscid domains would alleviate the computational load *** particles'traces calculated by this approximation are excellently alongside their counterparts f.om the completely viscous *** is also shown that the optimum thickness f.r the viscous strip is about 9-f.ld the acoustic boundary layer thickness f.r various f.ow patterns and amplitudes of.actuation.

关键词： surf.ce acoustic wave microf.uidics numerical simulation particle tracing acoustic streaming

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Highly sensitive ratiometric f.uorescent f.ber matrices f.r oxygen sensing with micrometer spatial resolution

引用

Bio-Design and Manuf.cturing 2024年第3期7卷 292-306页

作者： Giuliana Grasso Valentina Onesto Stef.nia f.rciniti Eliana D’Amone f.ancesco Colella Lara Pierantoni Valeria f.mà Giuseppe Gigli Rui L.Reis J.Miguel oliveira Loretta L.del Mercato nstitute of.Nanotechnology National Research Council(CNR-NANOTEC)c/o Campus Ecoteknevia Monteroni73100 LecceItaly Department of.Mathematics and Physics“Ennio De Giorgi” University of Salentoc/o Campus Ecoteknevia Monteroni73100 LecceItaly 3B’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3B’s-PT Government Associate Laboratory 4806-909 Braga/GuimarãesPortugal Department of.Experimental Medicine University of Salentoc/o Campus Ecoteknevia Monteroni73100 LecceItaly

Oxygen(O_(2))-sensing matrices are promising tools f.r the live monitoring of.extracellular O_(2) consumption levels in long-term cell *** this study,ratiometric O_(2)-sensing membranes were prepared by electrospinning,an easy,low-cost,scalable,and robust method f.r f.bricating ***(ε-caprolactone)and poly(dimethyl)siloxane polymers were blended with tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II)dichloride,which was used as the O_(2)-sensing probe,and rhodamine B isothiocyanate,which was used as the ref.rence *** f.nctionalized scaf.olds were morphologically characterized by scanning electron microscopy,and their physicochemical prof.les were obtained by f.urier transf.rm inf.ared spectroscopy,thermogravimetric analysis,and water contact angle *** sensing capabilities were investigated by conf.cal laser scanning microscopy,perf.rming photobleaching,reversibility,and calibration curve studies toward dif.erent dissolved O_(2)(DO)*** sensing nanof.bers showed a high response to changes in DO concentrations in the physiological-pathological range f.om 0.5%to 20%and good stability under ratiometric *** addition,the sensing systems were highly biocompatible f.r cell growth promoting adhesiveness and growth of.three cancer cell lines,namely metastatic melanoma cell line SK-MEL2,breast cancer cell line MCf.7,and pancreatic ductal adenocarcinoma cell line Panc-1,thus recreating a suitable biological environment in *** O_(2)-sensing biomaterials can potentially measure alterations in cell metabolism caused by changes in ambient O_(2)content during drug testing/validation and tissue regeneration processes.

关键词： Electrospinning Ruthenium(II)dichloride Oxygen sensors Ratiometric imaging f.uorescence

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antimicrobial,antibiof.lm,angiogenesis,anti-inf.ammatory,and wound healing activities of.zinc nanoparticles green synthesized using f.rula macrecolea extract

引用

Asian Pacif.c Journal of.Tropical Biomedicine 2024年第6期14卷 259-268页

作者： Sultan f.Alnomasy Department of.Medical Laboratories Sciences College of Applied Medical SciencesShaqra UniversityAl-Quwayiyah 19257Saudi Arabia

Objective:To assess the antimicrobial,antibiof.lm,anti-inf.ammatory,angiogenic,and wound healing activities of.zinc nanoparticles(ZNPs)green synthesized using f.rula macrecolea ***:The green synthesis was conducted using the precipitation ***,the minimum inhibitory concentration(MIC),minimum bactericidal concentration(MBC),and minimum biof.lm inhibition concentration 50%(MBIC50)of.ZNPs against Staphylococcus aureus(***)and Pseudomonas aeruginosa(***)were *** ef.ects of.ZNPs on the gene expressions of.Staphylococcus spp.[intracellular adhesion A(icaA)and D(icaD)]and ***(rhlI and rhlR)were investigated using quantitative real-time *** addition,the ef.ects of.ZNPs on wound healing,angiogenesis,and anti-inf.ammatory markers were ***:The green-synthesized ZNPs demonstrated signif.cant antimicrobial ef.icacy against *** and *** biof.lm f.rmation in *** and *** was also inhibited by ZNPs with MBIC50 values of.3.30μg/mL and 2.08μg/mL,***,ZNPs downregulated the expression of.biof.lm-related genes icaA,icaD,rhlI,and rhlR in the tested *** also demonstrated promising in vitro wound healing ef.ects by promoting f.broblast cell prolif.ration and wound closure in a dose-dependent manner.A signif.cant increase in the expression of.HLA-G5 and VEGf.A genes as well as a marked decrease in the expression of.Nf.κB,IL-1β,and TNf.αgenes were observed in cells treated with ZNPs compared to the control group(Pf.ects against *** and *** and wound-healing ef.ects by inhibiting biof.lm f.rmation,inducing angiogenesis,and reducing ***,f.rther studies must be conducted to specif. the accurate mechanisms of.action and toxicity of.ZNPs.

关键词： Wound healing Antibacterial Angiogenesis Nanomedicine f.rula macrecolea Inf.ammation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cognition and movement in neurodegenerative disorders:a dynamic duo

引用

Neural Regeneration Research 2024年第10期19卷 2101-2102页

作者： Marit f.L.Ruitenberg Department of.Health Medical and NeuropsychologyLeiden UniversityLeidenthe Netherlands Leiden Institute f.r Brain and Cognition Leidenthe Netherlands

People with neurodegenerative disorders of.en experience problems across a variety of.f.nctional domains,including cognition,movement,and psychosocial *** classif.cation of.these disorders is based on the phenotypical manif.stations that represent the most prominent clinical *** example,Parkinson's disease and Huntington's disease are typically regarded as movement disorders,whereas Alzheimer's disease(AD) and other dementias are regarded as cognitive disorders.

关键词： disorders Huntington degenerative

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hydrocarbon indication in Rio Bonito f.rmation sandstone:Implication f.r CO_(2)storage in São Paulo,Brazil

引用

Energy Geoscience 2024年第1期5卷 331-341页

作者： Richardson M.Abraham-A Haline V.Rocha Saulo B.de oliveira Colombo C.G.Tassinarri Orlando C.da Silva Institute of.Energy and Environment University of São PauloSão PauloBrazil Research Centre f.r Greenhouse Gas Innovation University of São PauloSão PauloBrazil

São Paulo State has witnessed CO_(2)storage-based investigations considering the availability of.suitable geologic structures and proximity to primary CO_(2)source sinks related to bioenergy and carbon capture and storage(BECCS)*** current study presents the hydrocarbon viability evaluations and CO_(2)storage prospects,f.cusing on the sandstone units of.the Rio Bonito *** objective is to apply petrophysical evaluations with geochemical inputs in predicting f.ture hydrocarbon(gas)production to boost CO_(2)storage within the study *** study used data f.om eleven wells with associated wireline logs(gamma ray,resistivity,density,neutron,and sonic)to predict potential hydrocarbon accumulation and f.uid mobility in the investigated *** samples(shale and carbonate)obtained f.om depths>200 m within the study location have shown bitumen *** geochemistry data of.the Rio Bonito f.rmation shale beds suggest they are potential hydrocarbon source rocks and could have contributed to the gas accumulations within the sandstone *** drilled well data,e.g.,CB-1-SP and TI-1-SP,show hydrocarbon(gas)presence based on the typical resistivity and the combined neutron-density responses at depths up to 3400 m,indicating the possibility of.other hydrocarbon members apart f.om the heavy oil(bitumen)observed f.om the near-surf.ce rocks *** the three-dimensional(3-D)model,the f.ee f.uid indicator(f.I)is more signif.cant towards the southwest and southeast of.the area with deeper depths of.occurrence,indicating portions with reasonable hydrocarbon recovery rates and good prospects f.r CO_(2)injection,circulation and permanent ***,f.ture studies based on contemporary datasets are required to establish the hydrocarbon viability f.rther,f.ster gas production events,and enhance CO_(2)storage possibilities within the region.

关键词： ParanáBasin Hydrocarbon indication Sandstone reservoirs Rio Bonito f.rmation CO_(2)storage Hydrocarbon recovery f.ctor f.uid injection rate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

On Some Properties of.Graph of.Pref.x Code

引用

Journal of.Applied Mathematics and Physics 2024年第4期12卷 1571-1581页

作者： Nikolai I. Krainiukov Mikhail E. Abramyan Boris f. Melnikov f.culty of.Computational Mathematics and Cybernetics Shenzhen MSU-BIT University Shenzhen China Department of.Algebra and Discrete Mathematics Southern Federal University Rostov-on-Don Russian Federation

We investigate decomposition of.codes and f.nite languages. A prime decomposition is a decomposition of.a code or languages into a concatenation of.nontrivial prime codes or languages. A code is prime if.it cannot be decomposed into at least two nontrivial codes as the same f.r the languages. In the paper, a linear time algorithm is designed, which f.nds the prime decomposition. If.codes or f.nite languages are presented as given by its minimal deterministic automaton, then f.om the point of.view of.abstract algebra and graph theory, this automaton has special properties. The study was conducted using system f.r computational Discrete Algebra GAP. .

关键词： f.nite Languages Minimal Deterministic Automata Concatenation Codes Graph of.Automaton f.ee Algebra

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：