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Chinese Journal Of Geochemistry 2006年第B8期25卷 24-24页

作者： olga L. Gaskova Svetlana B. Bortnikova Ivan v. Gaskov Institute of Geology and Mineralogy SB RAS

Agonist-directed sorting of β2-adrenergic receptor signaling and its therapeutic implication in heart

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郑州大学学报(医学版) 2000年第1期35卷 37-45页

作者： ZHANG Shengjun,XIAO Ruiping,ZHOU Yingying,Meike Kuschel,XIA Xianmin,Richard A.Bond ,olga v.Fedorova,Alex Y.Bagrov,C.Wiuiam Balke,Edward G.Lakatta,CHEN Heping Laboratory of Cardiovascular Science ,Gerontology Research Center,NIA,NIH,Baltimore,MD 21224

Cardiac β 2 adrenergic receptor (AR) dually couples to G s and to pertussis toxin(PTX) sensitive G i proteins ,resulting in opposing effects on cell *** we show that the coupling preference of β 2AR to the bifurcated signaling pathways,tested over wide ranges of agonist concentrations and receptor densities,is determined by agonist *** β 2AR agonists including zinterol,procaterol or salbutamol activate concurrent G s and G i signaling in both rat and mouse ventricular myocytes,as evidenced by a marked potentiating effect of PTX on contractile ***,however ,sorts the β 2AR primarily to G s signaling,as evidenced by the lack of effect of *** results were observed in transgenic mice overexpressing human β *** cells from failing rat hearts where the contractile response to zinterol was severely depressed due to an up regulation of G i,fenoterol,which activates G s bypassing the G i signaling pathway,rescued the diminished β 2AR ***,agonist directed sorting of receptor stimulus affords a novel therapeutic strategy to enhance desired “signaling specific”effects while avoiding adverse side effects of therapeutic agents.

关键词： adrenergic beta receptor agonists G protein toxins cell contra-ctihty

A Study of Calcifying Nanoparticles Extracted from the vorotilovskaya Well

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材料科学与工程（中英文B版） 2012年第8期2卷 464-470页

作者： Sergey v. vasile Anatoly B. Churilo olga Y. Prikhodko Alexander S. Rudy Nina v. Shekhovtsova Anastasiya Y. Yagushkina Facilities Sharing Centre "Micro-and Nanostructures Diagnosis" Yaroslavl State University 14 Sovetskaya street Yaroslavl150000 Russia Yaroslavl Branch of Physics and Technology Institute of Russian Academy of Sciences 21 Universitetskaya street Yaroslavl150007 Russia Department of Biology Yaroslavl State University 14 Sovetskaya street Yaroslavl 150000 Russia

One Aim-Several Goals： From Stem Cell to the Biofuel Production. The New Background Method for Zero Waste and High Efficiency Biodiesel Production from Microalgae Chlorella vulgaris

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材料科学与工程（中英文A版） 2014年第7期4卷 234-240页

作者： Elena v. Orlova Natalya I. Minkevich olga v. Prusakova valentina S. Orlova Artem M. Ermakov Evgeny I. Maevsky Stem Cells Technique & Nanocomposite Materials Group Institute of Theoretical and Experimental Biophysics (ITEB) RASMoscow District 142290 Russia Laboratory of Biological Systems Energy Institute of Theoretical and Experimental Biophysics (ITEB) RAS Moscow District142290 Russia Laboratory of Hormonal Regulation Proteins of Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry RAS Moscow11799 7 Russia Laboratory of Cell Engineering Institute of Theoretical and Experimental Biophysics (ITEB) R.AS Moscow District 142290 Russia Ecology Faculty System Ecology Chair Peoples' Friendship University of Russia Moscow 115093 Russia

Here, "one aim-several goals" background method for boosting (activating) biomaterials by weak low frequency magnetic field for many branches of biotechnology and medicine was presented. Our original method allows us to activate for the one hand the growth and reproduction of stem cells without any cancer transformations, with de novo expression of mRNA MDR gene, decreased apoptotic effects and in the required amount which could be the very important application in many branches of cancer therapy with standard chemotherapy procedures and without any fear about possible stem cells transformation into cancer cells. But for another hand it also could be the way for the biofuel production from microalgae Chlorella vulgaris. Such biofuel could be produced quickly and in large volumes, and biosafety waste products could use as a tool for rehabilitation of tsunami or radiation-affected soils

关键词：燃料生产生物柴油干细胞小球藻微藻废物癌症治疗低频弱磁场

Ion exchange recovery of palladium (II) from nitrate weak acidic solutions

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Natural Science（自然科学期刊） 2009年第3期

作者： olga N. Kononova Nataliya G. Goryaeva olga v. Dychko

Rural social-ecological systems navigating institutional transitions: case study from Transylvania (Romania)

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Ecosystem Health and Sustainability 2016年第2期2卷 25-37页

作者： Tibor Hartel Kinga-olga Réti Cristina Craioveanu Róbert Gallé Răzvan Popa Alina Ioniţă LászlóDemeter LászlóRákosy Bálint Czúcz Department of Environmental Sciences and Arts Sapientia Hungarian University of TransylvaniaStr.Calea Turzii 4Cluj-NapocaRomania Faculty of Environmental Science and Engineering RO-400294Fântânele street 30Babes-Bolyai UniversityCluj-NapocaRomania Department for Taxonomy and Ecology Str.Clinicilor 5-7400006Faculty of BiologyBabes-Bolyai UniversityCluj-NapocaRomania Department of Ecology Faculty of ScienceUniversity of SzegedH-6726 Szeged Közép fasor 52SzegedHungary Foundation ADEPT Str.Principala nr.166SaschizRomania Propark-Fundația pentru Arii Protejate BrasovStrada Lungă175500051Romania Misgurnus Association 530204 Miercurea-Ciucstr.Ion Caianu nr.67Romania MTA Centre for Ecological Research Institute of Ecology and BotanyAlkotmány u.2-42163VácrátótHungary

Traditional rural social-ecological systems(SES)share many features which are crucial for sus-tainable *** European countries such as Romania,are still rich in traditional cultural ***,these landscapes are increasingly under internal(e.g.,people’s aspirations toward western socioeconomic ideals)and external(institutional changes,globalization of the commodity market,connectivity with other cultures)***,understanding the ways how traditional SES navi-gated past and more recent changes is of crucial importance in getting insights about the future trajectory of these ***,we present the rural SES from the Saxon region of Transylvania through the lens of institutional transitions which happened in the past century in this *** show that the rural SES went through episodic collapses and renewals,their cyclic dynamic being related to the episodic chang-es of the higher level formal *** episodic collapses and renewals created a social-ecolog-ical momentum for the sustainability of these *** we recognize that policy effectiveness depends on institutional stability(and institutions are unstable and prone to collapses),maintaining those social-ecological system properties which can assure navigation of societies through the challenges imposed by global changes should be in the heart of every governance *** properties includes wide extent of native vegetation,fertile soils,wide range of provisioning ecosystem services,genuine links between people and landscapes and knowledge about the social-ecological *** features could provide important capitals and memory elements for the(re)emergence of social-ecological systems(old or new).

关键词： adaptive cycles collapse and renewal resilience social-ecological feedback social-ecological memory Special Feature:Ecosystem Management in Transition in Central and Eastern Europe sustainability.

Heterogeneity of Heterotrophic Bacteria Dominating in Brackish Lake Shira (Republic of Khakasia, Russia) Subjected to Anthropogenic Impact

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Journal of Water Resource and Protection（水资源与保护） 2010年第5期 389-395页

作者： Tatiana I. Lobova Yuriy v. Barkhatov olga v. Salamatina Ludmila Yu. Popova

The Effect of Balanced Hypocaloric Diet on the Anthropometric and Basic Metabolic Indicators in Infertile Women with Gluteofemoral Obesity

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Open Journal of Obstetrics and Gynecology（妇产科期刊） 2019年第10期

作者： Natalia v.Artymuk Natalia A.Sukhova olga A.Tachkova Moamar Al-Jefout

Capecitabine for locally advanced and metastatic colorectal cancer:A review

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World Journal of Gastrointestinal Oncology 2010年第8期2卷 311-321页

作者： Georgios v Koukourakis Georgios Zacharias John Tsalafoutas Dimitrios Theodoridis vassilios Kouloulias Department of Radiation Oncology Anticancer Institute of Athens "Saint Savvas" Section of Intensive Therapy General Hospital of Corinth Department of Radiation Physics Anticancer Institute of Athens "Saint Savvas" Department of Laboratory Medicine "Saint Olga" General Hospital of Athens Section of Radiation Oncology University Hospital of Athens "ATTIKON"

Capecitabine (Xeloda) is an oral fluoropyrimidine which is produced as a pro-drug of fluorouracil, and shows improved tolerability and intratumor drug concentrations following its tumor-specif ic conversion to the active drug. We have searched the Pubmed and Cochrane databases from 1980 to 2009 with the purpose of reviewing all available information on Capecitabine, focusing on its clinical effectiveness against colorectal cancer. Special attention has been paid to trials that compared Capecitabine with standard folinic acid (leucovorin, Lv)-modulated intravenous 5-fluorouracil (5-FU) bolus regimens in patients with metastatic colorectal cancer. Moreover the efficacy of Capecitabine on metastatic colorectal cancer, either alone or in various combinations with other active drugs such as Irinotecan and Oxaliplatin was also assessed. Finally, neoadjuvant therapy con- sisting of Capecitabine plus radiation therapy, for locally advanced rectal cancer was analysed. This combination of chemotherapy and radiotherapy has a special role in tumor down staging and in sphincter preservation for lower rectal tumors. Comparative trials have shown that Capecitabine is at least equivalent to the standard Lv-5-FU combination in relation to progression-free and overall survival whilst showing a better tolerability prof ile with a much lower incidence of stomatitis. It is now known that Capecitabine can be combined with other active drugs such as Irinotecan and Oxaliplatin. The combination of Oxaliplatin with Capecitabine represents a new standard of care for metastatic colorectal cancer. Combinating the Capecitabine-Oxaliplatin regimen with promising new biological drugs such as Bevacizumab seems to give a realistic prospect of further improvement in time to progression of metastatic disease. Moreover, preoperative chemo-radiation using oral capecitabine is better tolerated than bolus 5-FU and is more effective in the promotion of both down-staging and sphincter preservation in patie

关键词： Chemo-radiotherapy Colorectal cancer Capecitabine Oxaliplatin Xeloda

Regularities of Nanofocusing of the Electromagnetic Field of a Fractal Rough Surface

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Journal of Electromagnetic Analysis and Applications（电磁分析与应用期刊） 2019年第8期

作者： Nikolay N.Grinchik Galina M.Zayats olga v.Boiprav Kirill v.Dobrego volha A.Prykhodzka