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Accuracy of Helicobacter pylori serology in two peptic ulcer populations and in healthy controls

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World Journal of Gastroenterology 2008年第32期14卷 5039-5045页

作者： rolv-ole Lindsetmo roar Johnsen Tor Jac Eide Tore Gutteberg Hanne Haukland Husum Arthur revhaug Department of Gastrointestinal Surgery University Hospital of North Norway and Institute of Clinical Medicine Troms University Institute of Public Health and General Practice Norwegian University of Science and Technology Department of Pathology National Hospital Department of Microbiology University Hospital of North Norway

AIM： To estimate the test characteristics of Heli- cobacter pylori （H pylori） serology and of C14-urea breath test （C14-UBT） in two different peptic ulcer populations and in community controls. Second, the aim was to explore the association between the level of Hpylori IgG antibodies and severity of inflammation as to active peptic ulceration in the same populations. METHODS： Vagotomized （n = 83）, medically treated peptic ulcer patients （n = 73） and one reference group of community controls （n = 88） were gastroscoped. H pylori status was determined by histology, bacterial growth, C14-UBT and serology. Based on the updated Sydney System, cumulative scores from biopsies from the prepyloruos, incisura angularis, corpus and fundus were calculated. rESULTS： The prevalence of Hpylori infection varied from 70% to 79%. The C14-UBT had high accuracy compared to the serology test. The sensitivity of the serology test was good, but the specificity was low （41%-71%）. The association between H pylori IgG antibodies and scores of gastric mucosal inflammation and current or previous peptic ulcer were weak. CONCLUSION： The accuracy of CI4-UBT to diagnose Hpylori infection was good, and the clinical utility of a negative H pylori serology test was substantial, while the gain in clinical information of a positive test was meagre. Positive H pylori titres could not distinguish between subjects with or those without active peptic ulceration.

关键词： C14-urea breath test Gastric inflammation Helicobacter pylori serology Peptic ulcers Test characteristics

物流运输调度问题的混沌烟花算法——基于多车型供应链

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计算机工程与应用 2019年第3期55卷 238-244页

作者：蔡延光戚远航蔡颢陈厚仁 ole Hejlesen 广东工业大学自动化学院广州510006 奥尔堡大学健康科学与工程系

为了满足供应链物流的不同需求,考虑多种车型、车辆容量、车辆油耗、车辆最大配送距离等约束条件,以最小油耗、最短配送距离为目标,建立多车型供应链物流运输调度模型(Multi-Type Vehicle routing Problem in Supply Chain,MTVrPSC),并... 详细信息

为了满足供应链物流的不同需求,考虑多种车型、车辆容量、车辆油耗、车辆最大配送距离等约束条件,以最小油耗、最短配送距离为目标,建立多车型供应链物流运输调度模型(Multi-Type Vehicle routing Problem in Supply Chain,MTVrPSC),并提出一种混沌烟花算法求解该模型。该算法以烟花算法为核心,提出一种编解码策略实现连续空间到MTVrPSC离散空间的映射,重新定义算法的适应度函数、适应度值和适应度的比较方法,并采用混沌初始化策略和混沌搜索策略来增强算法收敛效果。实验结果表明,所提出的算法在求解MTVrPSC时具有较强的寻优能力和稳定性。

关键词：烟花算法混沌优化算法供应链车辆路径问题

短期高脂饮食对中国汉族男性2型糖尿病患者糖脂代谢的影响

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中国医学科学院学报 2008年第4期30卷 509-515页

作者：李文慧肖新华于康孙琦杨国华王姮 ole Schmitz 中国医学科学院北京协和医学院北京协和医院内分泌科北京100730 中国医学科学院北京协和医学院北京协和医院临床营养科北京100730 Department of Medicine M(Endocrinology & Diabetes) University Hosptial of AarhusDenmark

目的研究短期高脂饮食对中国汉族男性2型糖尿病(T2DM)患者糖脂代谢的影响。方法9例单纯饮食控制或仅用二甲双胍治疗的男性2型糖尿病患者先后分别服用高碳水化合物餐(HCD)和高脂肪餐(HFD)3 d,进食第3天多点抽血,测定血浆葡萄糖及胰岛素变... 详细信息

目的研究短期高脂饮食对中国汉族男性2型糖尿病(T2DM)患者糖脂代谢的影响。方法9例单纯饮食控制或仅用二甲双胍治疗的男性2型糖尿病患者先后分别服用高碳水化合物餐(HCD)和高脂肪餐(HFD)3 d,进食第3天多点抽血,测定血浆葡萄糖及胰岛素变化,并于第4天行静脉葡萄糖耐量试验(IVGTT)。结果进食HFD患者的非酯化脂肪酸(NEFA)24 h曲线下面积(AUC)显著高于进食HCD患者(P<0.001),且其24 h血浆葡萄糖AUC显著低于HCD患者(P<0.05);而24 h胰岛素AUC两种饮食患者差异无显著性;进食HFD患者72 h后空腹血浆葡萄糖接近显著意义地升高(P=0.056),低密度脂蛋白胆固醇水平升高(P<0.05)。IVGTT进食HFD患者葡萄糖刺激的胰岛素快速反应接近显著意义地升高(P=0.06),血浆空腹和早餐段餐后胰升血糖素亦显著升高。结论短期进食HFD使NEFA暴露水平显著升高,葡萄糖暴露水平显著降低,空腹血浆葡萄糖升高但不伴胰岛素水平的显著变化可能是肝糖输出增加、胰岛素抵抗形成的早期表现,提示胰升血糖素在胰岛素抵抗的形成中起了重要作用,而显著的β细胞功能失调(脂毒性)可能需要更长时间。

关键词：高脂饮食 2型糖尿病糖脂代谢胰岛素抵抗

Changes in Barents Sea ice Edge Positions in the Last 440 years: A review of Possible Driving Forces

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International Journal of Astronomy and Astrophysics 2020年第2期10卷 97-164页

作者： Nils-Axel Mö rner Jan-Erik Solheim ole Humlum Stig Falk-Petersen Paleogeophysics & Geodynamics Stockholm Sweden Department of Physics and Technology UiT The Arctic University of Norway Troms&oslash Norway The University Centre on Svalbard (UNIS) Longyearbyen Svalbard Norway The Fram Centre Akvaplan-niva Troms&oslash Norway

This is the first report of the Barents Sea Ice Edge (BIE) project. The BIE position has varied between latitude 76°N and above 82°N during the last 440 years. During the period 10,000 to 6000 years ago, Arctic climate was significantly warmer than today. We review various oceanic and atmospheric factors that may have an effect on the BIE position. The Gulf Stream beat with respect to alternations in flow intensity and N-S distribution plays a central role for the changes in climate and BIE position during the last millennium. This occurred in combination with external forcing from total solar irradiation, Earth’s shielding strength, Earth’s geomagnetic field intensity, Earth’s rotation, jet stream changes;all factors of which are ultimately driven by the planetary beat on the Sun, the Earth and the Earth-Moon system. During the last 20 years, we see signs of changes and shifts that may signal the end of the late 20th century warm period. The BIE position is likely to start advancing southward in next decade.

关键词： Barents Sea Ice Edge Cyclic Changes Gulf Stream Beat Planetary-Solar Forcing

Changes in Barents Sea Ice Edge Positions in the Last 442 Years. Part 2: Sun, Moon and Planets

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International Journal of Astronomy and Astrophysics 2021年第2期11卷 279-341页

作者： Jan-Erik Solheim Stig Falk-Petersen ole Humlum Nils-Axel Mö rner retired Department of Physics and Technology UiT The Arctic University of Norway Troms&oslash Norway Akvaplan-niva The Fram Centre Troms&oslash Norway The University Centre on Svalbard (UNIS) Longyearbyen Svalbard Norway Department of Geosciences University of Oslo Oslo Norway Deceased Paleogeophysics & Geodynamics Stockholm Sweden

This is the second paper in a series of two, which analyze the position of the Barents Sea ice-edge (BIE) based on a 442-year long dataset to understand its time variations. The data have been collected from ship-logs, polar expeditions, and hunters in addition to airplanes and satellites in recent times. Our main result is that the BIE position alternates between a southern and a northern position followed by Gulf Stream Beats (GSBs) at the occurrence of deep solar minima. We decompose the low frequency BIE position variations in cycles composed of dominant periods which are related to the Jose period of 179 years, indicating planetary forcings. We propose that the mechanism transferring planetary signals into changes in BIE position is the solar wind (SW), which provides magnetic shielding of the Earth in addition to geomagnetic disturbances. Increase in the solar wind produces pressure which decelerates the Earth’s rotation. It also transfers electrical energy to the ring current in the earth’s magnetosphere. This current magnetizes the earth’s solid core and makes it rotate faster. To conserve angular momentum the earth’s outer fluid mantle rotates slower with a delay of about 100 years. In addition will geomagnetic storms, initiated by solar coronal mass ejections (CMEs) penetrate deep in the Earth’s atmosphere and change pressure pattern in the Arctic. This effect is larger during solar minima since the magnetic shielding then is reduced. The Arctic may then experience local warming. The transition of solar activities to a possibly deep and long minimum in the present century may indicate Arctic cooling and the BIE moving south this century. For the North Atlantic region, effects of the BIE expanding southward will have noticeable consequences for the ocean bio-production from about 2040.

关键词： Barents Sea Ice Edge Position Cyclic and Non-Linear Changes Lunar and Solar Forcing Planetary Orbit Synchronization

Change in Preoperative Nervousness: A randomized Controlled Trial in Gynecological Cancer Patients

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Health 2016年第3期8卷 219-229页

作者： Marianne K. Thygesen rené De Pont Christensen Lone Hedemand ole Mogensen Institute of Clinical research Faculty of Health Sciences University of Southern Denmark Odense Denmark Department of Obstetrics and Gynaecology Odense University Hospital Odense Denmark research Unit of General Practice University of Southern Denmark Odense Denmark

Patients are often nervous prior to surgery and females might suffer the most. Increased nervousness needs attention as it can negatively affect postoperative recovery. Support from nurses, i.e. being present, attentive, empowering and helpful to the patient, and talking about what is on the patient’s mind, might help to reduce nervousness. However, there is a lack of evidence as to the ideal level of attention and resources to reduce preoperative nervousness. The objective of the current study was to compare a range of care combinations with standard care to female patients prior to sedation and cancer surgery primarily on difference in change in nervousness from admission until sedation before cancer surgery, measured on a Visual Analouge Scale. Using simple randomization and numbers in sealed envelopes, adult gynaecological patients scheduled for open cancer surgery were allocated to care provided by a nurse anaesthetist and: A) a surgical nurse, B) no additional care, C) a known nurse , and D) a relative. Only the statistician was blinded. The trial stopped when the calculated numbers were included. In the full analysis set, compared to standard care A) (n = 61), we observed the following mean changes and [95% confidence intervals]: B) (n = 65) 1.05 [CI: 0.298 to 1.794] with p = 0.006, C) (n = 61): -0.38 [-1.140 to 0.385] with p = 0.330, D) (n = 71): 0.23 [-0.498 to 0.967] with p = 0.528. Female cancer patients will benefit from supportive care by a surgical nurse from the time of arrival on the operating ward plus supportive care from a nurse anesthetist from 5 - 10 minutes after entering the operating ward. It is not recommended at any time to rely fully on the support of relatives. The effect on adults of preoperative painful procedures and patients’ time alone on the operating ward should be further investigated.

关键词： Anxiety Cancer Perioperative Care randomized Controlled Trial Women’s Health

ECOOP 2000 — Object-Oriented Programming: 14th European Conference Sophia Antipolis and Cannes, France, June 12–16, 2000 Proceedings 1

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Energetic Consequences of Stranding of Juvenile Atlantic Salmon(Salmo salar L.)

丛书名： Lecture Notes in Computer Science 1850

2000年

作者： ole Lehrmann Madsen (auth.) Elisa Bertino (eds.)

来源：畅想之星图书光盘版（南... 评论

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Journal of Water resource and Protection 2017年第2期9卷 163-182页

作者： Michael Puffer ole Kristian Berg Sigurd Einum Svein Jakob Saltveit Torbjorn Forseth Department of Biology Norwegian University of Science and Technology(NTNU)TrondheimNorway Freshwater Ecology&Inland Fisheries Laboratory Natural History MuseumUniversity of OsloOsloNorway Norwegian Institute for Nature research TrondheimNorway

An effect of hydropower and hydropeaking regulation in rivers is stranding of fish. Those fishes that survive stranding may experience stranding as a stressful situation. In four experimental stranding experiments (each with 6 individuals in 10 control and 10 treatment replicates), the energetic consequences of two forms of stranding (i.e. trapping and beaching) of juvenile Atlantic salmon (Salmo salar) were investigated in summer and winter. restricted food access in the experimental channels ensured that effects of hydropeaking could be revealed. Mean fish length ranged between 60 mm and 110 mm among experiments. Both during the winter and summer experiments fish did not grow in length, neither in the control nor in the treatment channels and fish lost body mass as well as body fat in all experiments (body fat in summer trapping experiment not determined). The four experiments revealed similar results: stranding did not affect growth or energy content. Despite the severity of the stranding and the resulting mortality, which was especially high during summer, no stranding related effects on fish performance could be detected.

关键词： Hydropeaking Trapping Beaching Growth Lipid Stores Salmonids

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建筑的学、思、行

住区 2017年第3期 94-100页

作者： ole Moystad 挪威科技大学

创新是指把一种状况变为另一种，或者把一个事物转换为另一个。教育可以从两个维度来理解：一是老师把知识传授给学生；二是主动进入学习过程。除非知识是始终如一且恒久不变的，否则创新应在第二种情况中起最大作用。下文我们将阐述学... 详细信息

创新是指把一种状况变为另一种，或者把一个事物转换为另一个。教育可以从两个维度来理解：一是老师把知识传授给学生；二是主动进入学习过程。除非知识是始终如一且恒久不变的，否则创新应在第二种情况中起最大作用。下文我们将阐述学习的过程。

关键词：建筑知识传授学习过程两个维度创新学生老师教育