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Asian Journal of Urology 2020年第2期7卷 161-169页

作者： Anne Holck Storas Martin GSanda olatz garin Peter Chang Dattatraya Patil Catrina Crociani Jose Francisco Suarez Milada Cvancarova Jon Havard Loge Sophie DFossa Department of Oncology Oslo University HospitalThe Norwegian Radium HospitalOsloNorway Department of Urology Emory University HospitalAtlantaUSA IMIM Hospital del Mar Medical Research Institute CIBER en Epidemiologıa y Salud PublicaCIBERESPUniversitat Pompeu FabraBarcelonaSpain Beth Israel Deaconess Medical Center Harvard Medical SchoolBostonUSA Emory University Hospital AtlantaUSA Hospital Universitary de Bellvitge BarcelonaSpain University of Oslo OsloNorway

Objective:To compare pre-and post-radical prostatectomy(RP)responses in the urinary incontinence domain of Expanded Prostate Cancer Index Composite-26(EPIC-26)in cohorts from the USA,Norway and ***:A prospective study of pre-and 1-year post-treatment responses in American(nZ537),Norwegian(nZ520)and Spanish(nZ111)patients,establishing the prevalence of urinary incontinence defined according to published *** we focused on the response alternatives“occasional dribbling”,pad use and problem experience.A multivariate logistic regression analysis(significance level≤0.01)considered risk factors for“not retaining total control”.

关键词： Prostate cancer Radical prostatectomy Urinary incontinence Adverse effects

Inhaler Technique Questionnaire(InTeQ)in pediatric patients with asthma

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世界儿科杂志:英文版 2023年第8期19卷 798-804页

作者： Catalina Lizano‑Barrantes olatz garin Alexandra Lelia Dima Karina Mayoral Angels Pont Eva María Ortiz María Araceli Caballero‑Rabasco Manuel Praena‑Crespo Laura Valdesoiro‑Navarrete María Teresa Guerra Alberto Bercedo‑Sanz Gimena Hernández Camila Maroni Inés de Mir MaríaÁngeles Carrasco Marta Ortega Alberto Servan JoséAntonio Castillo Eva Tato Montse Ferrer Health Services Research Group IMIM(Hospital del Mar Medical Research Institute)Barcelona Biomedical Research ParkDoctor Aiguader8808003 BarcelonaSpain Department of Medicine and Life Sciences Universitat Pompeu FabraBarcelonaSpain Department of Pharmaceutical Care and Clinical Pharmacy Faculty of PharmacyUniversidad de Costa RicaSan JoseCosta Rica Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública CIBERESP MadridSpain Research and Development Unit Institut de Recerca Sant Joan de DéuBarcelonaSpain Department of Pediatrics Obstetrics and Gynaecology and Preventive MedicineUniversitat Autònoma de BarcelonaBarcelonaSpain Pediatric Allergy and Pulmonology Unit Pediatric ServiceHospital del MarBarcelonaSpain Pediatric Allergy and Pulmonology Unit Pediatric ServiceHospital Universitari Parc TaulíSabadellSpain Centro de Salud La Candelaria Servicio Andaluz de SaludSevilleSpain Grupo de Vías Respiratorias de La Asociación Española de Pediatras de Atención Primaria(AEPAP) MadridSpain Centro de Salud Jerez Sur Servicio Andaluz de SaludSevilleSpain Centro de Salud La Sagrera BarcelonaSpain Centro de Salud Los Castros CantabriaSpain Facultat de Medicina Universitat Autònoma de BarcelonaBarcelonaSpain Pediatric Allergy and Pulmonology and Cystic Fibrosis UnitHospital Universitari Vall d’HebronBarcelonaSpain Consultorio Sevilla la Nueva MadridSpain Centro de Salud Dos de Mayo MadridSpain Hospital Miguel Servet ZaragozaSpain Hospital Universitario Araba Vitoria-GasteizSpain Departamento de Farmacologia Pediatría y RadiologíaUniversidad de SevillaSevilleSpain Institut d’Investigaciói InnovacióParc Taulí SabadellSpain

Asthma in school-aged children is a major public health problem worldwide[1,2].Inhaled medications are the mainstay of its pharmacological management[2],but only 8%-22%of children with asthma use their inhalers correc... 详细信息

关键词： asthma pediatric patients

Chloroplast Proteomics and the Compartmentation of Plastidial Isoprenoid Biosynthetic Pathways

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Molecular Plant 2009年第6期2卷 1154-1180页

作者： Jacques Joyard Myriam Ferro Christophe Masselon Daphne Seigneurin-Berny Daniel Salvi Jerome garin Norbert Rolland Laboratoire de Physiologie Cellulaire Vegetale UMR 5168 CEA CNRS INRA Universite Joseph Fourier iRTSV CEA-Grenoble 38054 Grenoble-cedex 9 France Laboratoirre Etude de la Dynamique des Proteomes U880 CEA INSERM Universite Joseph Fourrier iRTSV CEA-Grenoble 38054 Grenoble-cedex 9 France

Recent advances in the proteomic field have allowed high-throughput experiments to be conducted on chloroplast samples. Many proteomic investigations have focused on either whole chloroplast or sub-plastidial fractions. To date, the Plant Protein Database （PPDB, Sun et al., 2009） presents the most exhaustive chloroplast proteome available online. However, the accurate localization of many proteins that were identified in different sub-plastidial compartments remains hypothetical. Ferro et al. （2009） went a step further into the knowledge of Arabidopsis thaliana chloroplast proteins with regards to their accurate localization within the chloroplast by using a semi-quantitative proteomic approach known as spectral counting. Their proteomic strategy was based on the accurate mass and time tags （AMT） database approach and they built up AT_CHLORO, a comprehensive chloroplast proteome database with sub-plastidial localization and curated information on envelope proteins. Comparing these two extensive databases, we focus here on about 100 enzymes involved in the synthesis of chloroplast-specific isoprenoids. Well known pathways （i.e. compartmentation of the methyl erythritol phosphate biosynthetic pathway, of tetrapyrroles and chlorophyll biosynthesis and breakdown within chloroplasts） validate the spectral counting-based strategy. The same strategy was then used to identify the precise localization of the biosynthesis of carotenoids and prenylquinones within chloroplasts （i.e. in envelope membranes, stroma, and/or thylakoids） that remains unclear until now.

关键词： Non-mevalonate pathway chlorophyll biosynthesis chlorophyll degradation carotenoid biosynthesis prenylquinone biosynthesis envelope stroma thylakoids.

Acknowledgments to reviewers of World Journal of Clinical Pediatrics

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World Journal of Clinical Pediatrics 2012年第1期1卷 1-2页

作者： Eduardo H garin Department of Pediatrics University of Florida1600 SW Archer Road HD214GainesvilleFL 32610United States

The first issue of the World Journal of Clinical Pediatrics(WJCP),whose preparatory work was initiated on January 10,2011,will be published on June 8,*** WJCP editorial board has now been established and consists of 100 distinguished experts from 31 *** purpose of launching the WJCP is to publish peer-reviewed,high-quality articles via an open-access online publishing model,thereby acting as a platform for communication between peers and the wider public,and maximizing the benefits to editorial board members,authors and readers.

关键词： Pediatrics Peer-reviewed Open-access Journal

Incidental anal ^18fluorodeoxyglucose uptake:Should we further examine the patient?

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World Journal of Clinical Cases 2020年第17期8卷 3679-3690页

作者： Anne-Sophie Moussaddaq Charlene Brochard Xavier Palard-Novello Etienne garin Timothee Wallenhorst Eric Le Balc’h Alexandre Merlini L’heritier Thomas Grainville Laurent Siproudhis Astrid Lievre Department of Gastroenterology University Hospital of RennesPontchaillouRennes 35000France Inphy CIC 1414 University Hospital of Rennes PontchaillouRennes 35000France Department of Nuclear Medicine Cancer Institute Eugène MarquisRennes 35000France Laboratoire Traitement du Signal et de l'Image-UMR1099 University of RennesInsermRennes 35000France

BACKGROUND There are no studies on incidental anal ^18F-fluorodeoxyglucose(^18FDG)*** To assess the rate and aetiologies of incidental anal ^18FDG uptake and to evaluate the correlation between ^18FDG positron-emission tomography/computed tomography(PET/CT)parameters and the diagnosis of an anorectal *** The data from patients with incidental anal ^18FDG uptake were retrospectively *** who underwent anorectal examinations were identified and compared to those who did not undergo *** who were offered treatment were then identified and compared to those who did not receive *** Among the 43020^18FDG PET/CT scans performed,197^18FDG PET/CT scans of 146 patients(0.45%)reported incidental anal *** the 134 patients included,48(35.8%)patients underwent anorectal examinations,and anorectal diseases were diagnosed in 33(69.0%)of these patients and treated in ^18/48(37.5%)*** the examined patients,those with a pathology requiring treatment had significantly smaller metabolic volumes(MV)30 and MV41 values and higher maximal and mean standardized uptake value measurements than those who did not require *** Incidental anal ^18FDG uptake is rare,but a reliable anorectal diagnosis is commonly obtained when an anorectal examination is *** diagnosis of an anorectal disease induces treatment in more than one-third of the *** data should encourage practitioners to explore incidental anal ^18FDG uptake systematically.

关键词： Incidental anal^18fluorodeoxyglucose uptake Anorectal disease Rare

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于齐诺尔炼焦厂煤的选择和配煤技术

国外炼焦化学 1990年第4期9卷 1-8页

作者： garin,J 桂明玺

A Density Functional Theory Study of Methoxy and Atomic Hydrogen Chemisorption on Au(100) Surface

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Journal of Modern Physics 2013年第3期4卷 409-417页

作者： M. N’dollo P. S. Moussounda T. Dintzer F. garin Groupe de Simulations Numériques en Magnétisme et Catalyse Département de PhysiqueFaculté des Sciences Université Marien Ngouabi Brazzaville Congo Laboratoire des Matériaux Surfaces et Procédés pour la Catalyse (LMSPC) Université de Strasbourg Strasbourg France

The adsorption of CH3O and H on the (100) facet of gold was studied using self-consistent periodic density functional theory (DFT-GGA) calculations. The best binding site, energy, and structural parameter, as well as the local density of states, of each species were determined. CH3O is predicted to strongly adsorb on the bridge and hollow sites, with the bridge site as preferred one, with one of the hydrogen atoms pointing toward a fourfold vacancy (bridge-H hollow). The top site was found to be unstable, the CH3O radical moving to the bridge –H top site during geometry optimization. Adsorption of H is unstable on the hollow site, the atom moving to the bridge site during geometry optimization. The 4-layer slab is predicted to be endothermic with respect to gaseous H2 and a clean Au surface.

关键词： Chemisorption Density Functional Calculations Gold Methoxy Hydrogen

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老龄焦炉故障诊断及寿命预测

设计通讯 1995年第2期 42-48,F003,F00页

作者： garin,J 刘世庆

对EDTA血清凝集试验诊断牛布氏杆菌病的评价

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中国牦牛 1987年第3期 57-58页

作者： B.garin D.TraP R.Gaumont 杨宏

在法国,由于一些不符合标准的牛布氏杆菌病检测方法的使用,使卫生管理部门大伤脑筋。在这种状况下,出现了一些消除牛布氏杆菌病的研究进展。例如:在已经几年都无牛布氏杆菌病的牛群中,仍出现血清学反应的结果,但往往是非特异性凝集所致... 详细信息

在法国,由于一些不符合标准的牛布氏杆菌病检测方法的使用,使卫生管理部门大伤脑筋。在这种状况下,出现了一些消除牛布氏杆菌病的研究进展。例如:在已经几年都无牛布氏杆菌病的牛群中,仍出现血清学反应的结果,但往往是非特异性凝集所致。使用 EDTA(乙二胺四乙酸——译者)改良抗原似乎可以减少这类非特异性凝集。Scheibner(1976a,b)对此首先作了报道,接着 Nielsen 等(1979,1980,1981)

关键词：牛布氏杆菌病血清凝集试验流产布氏杆菌非特异性凝集反应 EDTA 络合试剂

69例1型神经纤维瘤病患者的恶性周围神经鞘瘤相关症状的回顾性研究

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世界核心医学期刊文摘（皮肤病学分册） 2005年第10期1卷 26-27页

作者： Valeyrie-Allanore L Ism.li N Bastuji-garin S P. Wolkenstein 罗素菊 Department of Dermatology Paris XII University Henri-Mondor Hospital F-94010 Créteil Cedex France

Background:Neurofibromatosis 1 (NF1) is a common genetic disorder with variable clinical manifestations and an unpredictable course. Plexiform neurofibromas are common complications of NF1. Their malignant transformation is the main cause of mortality in adult patients with NF1. Objectives:To identify clinical factors associated with malignant transformation of plexiform neurofibromas. Methods:Using the database of our neurofibromatosis clinic we included in a retrospective study all patients with NF1 having at least one peripheral nerve sheath tumour for which they underwent surgery or surgical biopsy. Predictive values for malignant transformation of three clinical symptoms, i.e. pain, enlargement of mass and neurological symptoms, were evaluated in association with histological parameters. Results:Of 69 patients studied, 48 had at least one plexiform neurofibroma and 21 had a malignant peripheral nerve sheath tumour. Only enlargement of the tumour had high negative and positive predictive values for malignant transformation:0.92 and 0.95, respectively. In multivariate analysis, tumour enlargement was independently associated with malignant transformation (OR 167.8,95%CI 14.0～2012.1). Conclusions:From a practical point of view, pain, neurological deficit and enlargement of a preexisting peripheral nerve sheath tumour in NF1 must lead to deep surgical biopsy to rule out malignant transformation.

关键词：神经纤维瘤病丛状神经纤维瘤神经鞘瘤组织学检查手术活检预测值死亡原因临床因素神经功能障碍多变量分析