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Ethyl and butyl acetate oxidation over manganese oxides

Chinese Journal of Catalysis 2018年第1期39卷 27-36页

作者： olívia Salomé G.P.Soares Raquel P.Rocha Jose J.M.orfao Manuel F.R.Pereira José L.Figueiredo Laboratory of Separation and Reaction Engineering‐Laboratory of Catalysis and Materials (LSRE‐LCM) Faculty of Engineering University of Porto Rua Dr. Roberto Frias s/n 4200‐465 Porto Portugal

Mangenese oxides were synthesized using two new methods,a novel solvent‐free reaction and a reflux technique,that produced cryptomelane‐type products(K‐oMS‐2).oxides were also synthesized using conventional methods and all specimens were applied to the oxidation of ethyl acetate and butyl acetate,acting as models for the volatile organic compounds found in industrial *** catalysts were also characterized using N2adsorption,X‐ray diffraction,scanning electron microscopy,temperature programmed reduction and X‐ray photoelectron *** of the manganese oxides was found to be very active during the oxidation of both esters to Co2,and the synthesis methodology evidently had a significant impact on catalytic *** K‐oMS‐2nanorods synthesized by the solvent‐free method showed higher activity than K‐oMS‐2materials prepared by the reflux technique,and samples with cryptomelane were more active than those prepared by the conventional *** catalyst with the highest performance also exhibited good stability and allowed90%conversion of ethyl and butyl acetate to Co2at213and202°C,*** differences in the catalyst performance were observed,clearly indicating that K‐oMS‐2nanorods prepared by the solvent‐free reaction were better catalysts for the selected VoC oxidations than the mixtures of manganese oxides traditionally obtained with conventional synthesis *** superior performance of the K‐oMS‐2catalysts might be related to the increased average oxidation state of the manganese in these *** correlations between the catalytic performance and the surface chemical properties were also identified,hig-hlighting the K‐oMS‐2properties associated with the enhanced catalytic performance of the materials.?2018,Dalian Institute of Chemical Physics,Chinese Academy of *** by Elsevier *** rights reserved.

关键词： Volatile organic compound Ethyl acetate Butyl acetate Manganese oxide Catalytic oxidation

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A new look at epicardial adipose tissue from the perspective of Iranian traditional medicine

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Journal of Integrative Medicine 2014年第6期12卷 529-530页

作者： Ali Reza Derakhshan Raso ol Choopani Sohrab Dehghan School of Traditional Medicine Traditional Medicine and Materia Medica Research Center Shahid Beheshti University of Medical Sciences

The fact that distribution of body fat can have a major role in the development of metabolic derangement and cardiovascular diseases is supported by a considerable amount of *** it is no surprise that increased of metabolic syndrome. New evidence describing adipose tissue as an advanced endocrine unit, capable of producing substances with remarkable physiologic impacts, has led to increased research interest in this field. While many fatty tissues are similar in composition, some of them, notably subcutaneous and visceral adipose tissues, possess special properties.

关键词： epicardial adipose tissue Iranian medicine traditional

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Mechanical Properties of Living Adherent Cells :Relationship with Structure and Function

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生物医学工程学杂志 2005年第S1期22卷 9-10页

作者： R. FoDIL S. Féréol E. PLANUS V.M. LAURENT B. LoUIS D. ISABEY Inserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 France

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Breast cancer:Muscarinic receptors as new targets for tumor therapy

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World Journal of Clinical oncology 2021年第6期12卷 404-428页

作者： Alejandro Español.agustina Salem Yamila Sanchez María Elena Sales Laboratory of Immunopharmacology and Tumor Biology CEFYBO CONICET University of Buenos AiresBuenos Aires C1121ABGArgentina

The development of breast cancer is a complex process that involves the participation of different *** authors have demonstrated the overexpression of muscarinic acetylcholine receptors(mAChRs)in different tumor tissues and their role in the modulation of tumor biology,positioning them as therapeutic targets in *** conventional treatment for breast cancer involves surgery,radiotherapy,and/or *** latter presents disadvantages such as limited specificity,the appearance of resistance to treatment and other side *** prevent these side effects,several schedules of drug administration,like metronomic therapy,have been *** therapy is a type of chemotherapy in which one or more drugs are administered at low concentrations ***,two chemotherapeutic agents usually used to treat breast cancer have been considered able to activate *** combination of low concentrations of these chemotherapeutic agents with muscarinic agonists could be a useful option to be applied in breast cancer treatment,since this combination not only reduces tumor cell survival without affecting normal cells,but also decreases pathological neo-angiogenesis,the expression of drug extrusion proteins and the cancer stem cell *** this review,we focus on the previous evidences that have positioned mAChRs as relevant therapeutic targets in breast cancer and analyze the effects of administering muscarinic agonists in combination with conventional chemotherapeutic agents in a metronomic schedule.

关键词： Muscarinic receptors Drug therapy Breast cancer Drug combination Metronomic therapy Drug resistance

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Medications for diabetic neuropathy

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中华物理医学与康复杂志 2015年第2期37卷 85-85页

作者： Griebeler ML Morey-Vargas ol Brito JP

BACKGRoUND AND oBJECTIVE Diabetic neuropathy is a common, long-term complication that can decrease quality of life. While various neuropathic agents are useful for treating this pain, choosing one or the other can be challenging. This systematic review investigated the relative effectiveness of various medications used for the treatment of diabetic *** Databases were reviewed for randomized, controlled trials published between January of 2012 and April of 2014. The trials assessed the efficacy of medications for treating diabetic neuropathy, and compared the medication to placebo or to another *** Sixty-five, randomized, controlled trials, including 27 medications with 12, 632 patients analyzed. By drug class, SNRIs, topical capsaicin, TCAs, and anticonvulsants all resulted in larger and statistically significant reductions in pain, as compared with placebo. Head-to-head trials showed that SNRIs and TCAs reduced pain more than did anticonvulsants and topical capsaicin. Studies that evaluated long-term efficacy found that the aldose reductase inhibitors fidarestat, duloxetine and oxcarbazepine are all more effective than placebo. Indirect and direct comparisons among specific medications revealed greater pain control with carbamazepine, venlafaxine, duloxetine and amitriptyline as compared with *** This systematic review and meta-analysis of pharmacologic interventions for painful diabetic neuropathy found that carbamazepine, venlafaxine, duloxetine and amitriptyline are significantly better than placebo for controlling pain.

关键词：药物治疗糖尿病神经病变随机对照试验醛糖还原酶抑制剂度洛西汀试验评估

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伊丽莎白一世的领导力课程

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2008年

作者：肖恩·ol希金斯帕米拉·吉尔伯特赵明珠

在45年的执政生涯中，伊丽莎白一世创造了世界历史上政治和文化发展最具活力的时代之一。她取得的伟大成就来源于自身卓越的领导才能、明确的奋斗目标以及对国家和人民的坚定信念。不论是作为一位统治者，一位战略家，一位斗士还是作为... 详细信息

ISBN: (数字)9787811192018

在45年的执政生涯中，伊丽莎白一世创造了世界历史上政治和文化发展最具活力的时代之一。她取得的伟大成就来源于自身卓越的领导才能、明确的奋斗目标以及对国家和人民的坚定信念。不论是作为一位统治者，一位战略家，一位斗士还是作为一名女性，她都无人企及。那么，今天驰骋于商界且胸怀大志的人们，可以从这位女王身上学到些什么呢？首先，你会学到如何重整旗鼓；其次，你会学到如何提升品牌知名度；再者，你会学到如何建立一种全面发展的组织；除此之外，你还会学到组建团队的技巧；当然，你还能学到很多其他东西，比如，如何具备一种王者般的处世态度，如何在不断出现的困境中保持自信和担负职责等等。

关键词：企业领导学通俗读物

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溃疡性结肠炎患者的同期重建与分期重建及其手术失败风险:一项全国性队列研究

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结直肠肛门外科 2022年第1期28卷 84-85页

作者：付兆媛 WESTBERG K oléN o SoDERLING J 甘肃中医药大学附属医院消化科甘肃兰州730000 不详

背景:溃疡性结肠炎(UC)患者接受结肠切除术后的重建手术可以与结肠切除术同时进行,也可以作为分期手术进行。重建手术后失败的危险因素尚未完全明确。本研究旨在比较UC修复性手术同期重建与分期重建手术失败的风险。方法:这是一项基于... 详细信息

背景:溃疡性结肠炎(UC)患者接受结肠切除术后的重建手术可以与结肠切除术同时进行,也可以作为分期手术进行。重建手术后失败的危险因素尚未完全明确。本研究旨在比较UC修复性手术同期重建与分期重建手术失败的风险。方法:这是一项基于国家层面的队列研究,研究对象为1997—2017年瑞典15~69岁因UC接受结肠切除术并行回肠直肠吻合术(IRA)或回肠储袋肛管吻合术(IPAA)的患者。手术失败定义为在重建手术后再次进行新的回肠造口手术,或在2年后继续进行功能不全的回肠造口手术。

关键词：重建手术结肠切除术回肠直肠吻合术队列研究分期手术功能不全手术失败危险因素

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Nicotinic receptors modulate antitumor therapy response in triple negative breast cancer cells

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World Journal of Clinical oncology 2022年第6期13卷 505-519页

作者： Alejandro Español Yamila Sanchez Agustina Salem Jaqueline obregon Maria Elena Sales Laboratory of Immunopharmacology and Tumor Biology CEFYBO CONICET University of Buenos AiresBuenos Aires C1121ABGArgentina

BACKGRoUND Triple negative breast cancer is more aggressive than other breast cancer subtypes and constitutes a public health problem worldwide since it has high morbidity and mortality due to the lack of defined therapeutic *** to chemotherapy complicates the course of patients’*** authors have highlighted the participation of nicotinic acetylcholine receptors(nAChR)in the modulation of conventional chemotherapy treatment in cancers of the ***,in breast cancer,less is known about the effect of nAChR activation by nicotine on chemotherapy treatment in smoking *** To investigate the effect of nicotine on paclitaxel treatment and the signaling pathways involved in human breast MDA-MB-231 tumor *** Cells were treated with paclitaxel alone or in combination with nicotine,administered for one or three 48-h *** effect of the addition of nicotine(at a concentration similar to that found in passive smokers’blood)on the treatment with paclitaxel(at a therapeutic concentration)was determined using the 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** signaling mediators involved in this effect were determined using selective *** also investigated nAChR expression,and ATP“binding cassette”G2 drug transporter(ABCG2)expression and its modulation by the different treatments with Western *** effect of the treatments on apoptosis induction was determined by flow cytometry using annexin-V and 7AAD *** our results confirmed that treatment with paclitaxel reduced MDA-MB-231 cell viability in a concentration-dependent manner and that the presence of nicotine reversed the cytotoxic effect induced by paclitaxel by involving the expression of functionalα7 andα9 nAChRs in these *** action of nicotine on paclitaxel treatment was linked to modulation of the protein kinase C,mitogen-activated protein kinase,extracellular signal-regulated kinase,and NF-κB signaling pathways,

关键词： Breast cancer Paclitaxel Nicotinic acetylcholine receptors Drug therapy Signal transduction Drug transporter

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硬盘引导型故障分析及排除

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法制与经济 2005年第1X期14卷 60-61页

作者： ol小刀

硬盘是存储信息的重要介质，当硬盘出现故障后，迅速找准故障原因并排除是一项极其重要的工作，这里把病毒以外的故障分析如下，供参考：

关键词：故障分析硬盘引导型存储

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Nursing Diagnoses of the Domain Safety/Protection and Socioeconomic and Clinical Aspects of Critical Patients

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open Journal of Nursing 2016年第4期6卷 314-322页

作者： Anna Lívia de Medeiros Dantas Ana Beatriz de Almeida Medeiros Jéssica de Araújo olímpio Jéssica Dantas de Sá Tinôco Maria Isabel da Conceição Dias Fernandes Ana Luísa Brandão de Carvalho Lira Nursing Federal University of Rio Grande do Norte Natal Brasil The Nursing Department and Post-Graduate Nursing Program Federal University of Rio Grande do Norte Natal Brasil

objective: The objective is to correlate the nursing diagnoses of the domain Safety/Protection of NANDA-I in critically ill patients with sociodemographic and clinical data. Method: A cross-sectional study with 86 individuals was conducted, from october 2013 to May 2014 in the Intensive Care Unit of a university hospital in northeastern Brazil, through a formal interview and physical examination. Results: It was possible to identify a total of 20 significant statistical associations, and 15 were clinically justified by the literature, namely: risk for aspiration and reason for admission;impaired dentition and age;risk for peripheral neurovascular dysfunction and sex and comorbidity;skin integrity and comorbidity;risk for impaired skin integrity and gender and reason for admission;impaired tissue integrity and gender and reason for admission;risk for perioperative positioning injury and reason for admission;risk for thermal injury and age and comorbidity;delayed surgical recovery and reason for admission;risk for poisoning and years of schooling;and risk for imbalanced body temperature and age. Conclusions: By understanding the relationship between customers’ answers and the sociodemographic and clinical profile, positive health outcomes can be achieved in particular in the prevention of risks facing vulnerability characteristics, providing greater safety and protection for the critical customer.

关键词： Nursing Diagnosis Patient Safety Intensive Care

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