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Botulinum Toxin-A for the Treatment of Voiding Dysfunction: Our Initial Experience

Open Journal of Urology 2012年第2期2卷 67-71页

作者： Sinharib Citgez Bulent Onal Fetullah Gevher Cagatay Dogan Omer Kurt oktay Demirkesen Bulent Cetinel Department of Urology Cerrahpasa Medical Faculty University of Istanbul Istanbul Turkey

Objective: Evaluation of Botulinum Toxin-A (BTX-A) as an alternative treatment option in patients whom previous treatments were failed. Methods: Between March 2005 and September 2006, a total 19 patients;16 patients with overactive bladder (5 neurologic, 11 idiopathic), 2 with nocturnal enuresis, 1 with interstitial cystitis, intravesical BTX-A injection was applied. Except one patient, 18 patients with a median age 46 (20 - 80) were registered to the study. Patients were examined at postoperative 3 weeks and 6 months with ICIQ-SF (International Consultation on Incontinence Questionnaire-Short Form) and satisfaction forms used in our clinic. Results: The median follow-up time was 16 months (6 - 18). When evaluated according to diagnosis, symptoms were improved 100% in neurologic overactive bladder (5/5), 80% in idiopathic overactivity (8/10), 50% in nocturnal enuresis (1/2). In one patient with interstitial cystitis there was no improvement. Median efficiency time of BTX-A treatment was 6 months (1 - 17). At 3 weeks and 6 months after the treatment, ICIQ-SF score was decreased to 3.6 and 7.5 respectively from preoperative level of 18.7. Quality of life scores at preoperative, 3 week and 6 months were 9.7, 2.7 and 4.3 respectively. Except 3 patients with overactive neurologic bladder because of spinal cord injury, symptoms of patients with pollacuria and nocturia decreased at 3. week. Even if these rates increased at 6 months they still were significantly less than preoperative status. The spinal cord injured 3 patients had clean intermittent catheterization per 1 hour and had urinary incontinence between the catheterizations preoperatively, however at 3 weeks and 6 months the intervals of catheterisations was 4 hours and 3 hours respectively and also the urinary incontinance between the catheterisations improved. At patient satisfactions, 78% of patients declared that they were pleased and underwent the procedure again and will recommend it to their relatives with s

关键词： Botulinum Toksin-A Overactive Bladder Voiding Dysfunction

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土耳其东部的地震减灾工作和灾害管理对策

土耳其东部的地震减灾工作和灾害管理对策

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作者： oktay Ergunay 土耳其安卡拉灾害事务办公室

引言地震是土耳其的主要灾害。20世纪中土耳其的地震曾夺去7000多人的生命,并破坏350000座建筑物。据当时官方绘制的土耳其地震灾害区划图和1985年的人口统计数字,占国土总面积97%的地区和95%的人口都处在不同的地震带上。国家合成灾害...

引言地震是土耳其的主要灾害。20世纪中土耳其的地震曾夺去7000多人的生命,并破坏350000座建筑物。据当时官方绘制的土耳其地震灾害区划图和1985年的人口统计数字,占国土总面积97%的地区和95%的人口都处在不同的地震带上。国家合成灾害图认定的最可能遭受损失的区域和城市表明,由强烈地震造成损失的具有最高危险的地区都在土耳其东部。根据对过去地震造成破坏的统计验证,土耳其东部要比土耳其西部的死亡率高出70%,建筑物毁坏率高200%。土耳其之所以比别的地方更易于遭受地震袭击,是因为这一地区的建筑物都是由物主按照传统的结构自建为主,建筑材料也多是用易于遭受破坏的碎石-石头,并由泥灰浆砌筑成

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促进文明间的对话与国家间的和平:以土耳其为视角(英文)

促进文明间的对话与国家间的和平:以土耳其为视角(英文)

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北京论坛（2004）文明的和谐与共同繁荣

作者： oktay F. Tanrisever Middle East Technical University Ankara-TURKEY

In this paper, I will attempt to explore the relationship between multiculturalism and peace in the 21st century. It is in this context that the promotion of multiculturalism in the

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The Association between Serum Resistin Levels and Major Adverse Cardiac Events

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World Journal of Cardiovascular Diseases 2017年第10期7卷 332-339页

作者： Umit Yasar Sinan Ozge Cetinarslan Veysel oktay Ilknur Calpar Yalcin Dalgic Aysem Kaya Alev Arat Ozkan Murat K. Ersanli Department of Cardiology Istanbul University Institute of Cardiology Istanbul Turkey Department of Biochemistry Istanbul University Institute of Cardiology Istanbul Turkey

Resistin is a member of the family of cysteine-rich secretary proteins called resistin-like molecules (RELMs). It is suggested to be involved in inflammatory conditions and atherosclerosis. We have established a significant correlation between serum resistin levels and coronary artery disease (CAD) in a study was performed between 2011 and 2012 in our institute in two hundred fourteen patients (164 CAD patients and 50 controls). Then the CAD patients were followed up to investigate the relationship between increased serum resistin levels and major adverse cardiac events (MACE) between 2012 and 2016. One hundred fifty-five of 164 patients (95%) were followed up and 9 patients lost to follow up. There were 39 MACE (25%) in four years of follow-up.?There were 16 in-hospital deaths due to cardiac causes, 8 revascularization procedures, and 15 re-hospitalization due to acute coronary syndrome (ACS) or heart failure (HF). The patients with MACE had similar serum resistin level (median: 71.37 pg/ml) compared to patients without MACE (median: 80.23 pg/ml) (p > 0.05).

关键词： Resistin Adipokine Atherosclerosis Coronary Artery Disease Major Adverse Cardiac Event

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用彩色多普勒超声评估血液透析病人的甲状旁腺

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国际医学放射学杂志 2010年第1期 93-94页

作者： U.A.Ozcan I.oktay 田凤娟 Department of Radiology Acibadem University School of MedicineAcibadem Kozyatagi Hastanesi Inonu cd.Okur sk.KozyatagiIstanbulTurkey

这项研究的目的是评估彩色和频谱多普勒超声(color and spectral Doppler ultrasound,CDU)用于诊断血液透析继发甲状旁腺功能亢进的病人甲状旁腺增大的价值。对14例甲状旁腺激素水平升高的血液透析病人进行前瞻性彩色和频谱多普勒超声... 详细信息

这项研究的目的是评估彩色和频谱多普勒超声(color and spectral Doppler ultrasound,CDU)用于诊断血液透析继发甲状旁腺功能亢进的病人甲状旁腺增大的价值。对14例甲状旁腺激素水平升高的血液透析病人进行前瞻性彩色和频谱多普勒超声检查。记录每例病人甲状旁腺体积和频谱多普勒超声

关键词：甲状旁腺内分泌腺病人频谱多普勒血液透析透析疗法

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Skin disorders in peritoneal dialysis patients:An underdiagnosed subject

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World Journal of Nephrology 2016年第4期5卷 372-377页

作者： Meltem Gursu Sami Uzun Derya Topcuoglu Leyli Kadriye Koc Lamiye Yucel Abdullah Sumnu Egemen Cebeci oktay Ozkan Ahmet Behlul Leyla Koc Savas Ozturk Rumeyza Kazancioglu Department of Nephrology Bezmialem Vakif University Medical Faculty34093 IstanbulTurkey Department of Nephrology Haseki Training and Research Hospital34093 IstanbulTurkey Department of Dermatology Haseki Training and Research Hospital34093 IstanbulTurkey

AIM： To examine all skin changes in peritoneal dialysis （PD） patients followed up in our ***： Patients on PD program for at least three months without any known chronic skin disease were included in the study. Patients with already diagnosed skin disease, those who have systemic diseases that may cause skin lesions, patients with malignancies and those who did not give informed consent were excluded from the study. All patients were examined by the same predetermined dermatologist with all fndings recorded. The demographic, clinical and laboratory data including measures of dialysis adequacy of patients were recorded also. Statistical Package for Social Sciences （SPSS） for Windows 16.0 standard version was used for statistical ***： Among the patients followed up in our PD unit, those without exclusion criteria who gave informed consent, 38 patients were included in the study with male/female ratio and mean age of 26/12 and 50.3 ± 13.7 years, respectively. The duration of CKD was 7.86 ± 4.16 years and the mean PD duration was 47.1 ± 29.6 mo. Primary kidney disease was diabetic nephropathy in 11, nephrosclerosis in six, uropathologies in four, chronic glomerulonephritis in three, chronic pyelonephritis in three, autosomal dominant polycystic kidney disease in three patients while cause was unknown in eight patients. All patients except for one patient had at least one skin lesion. Loss of lunula, onychomycosis and tinea pedis are the most frequent skin disorders recorded in the study group. Diabetic patients had tinea pedis more frequently （ P = 0.045）. No relationship of skin findings was detected with primary renal diseases, comorbidities and medications that the patients were ***： Skin abnormalities are common in in PD patients. The most frequent skin pathologies are onychomycosis and tinea pedis which must not be overlooked.

关键词： Skin Peritoneal dialysis Onychomycosis Tinea pedis Xeroderma

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