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Developing an Evolutionary Algorithm to Search for an Optimal Multi-Mother Wavelet Packets Combination

Journal of Biomedical Science and Engineering 2015年第7期8卷 458-470页

作者： ohad bar siman tov J. David Schaffer Kenneth J. McLeod Department of Electrical and Computer Engineering State University of New York at Binghamton Binghamton NY USA Department of Bioengineering State University of New York at Binghamton Binghamton NY USA

The wavelet transform is a popular analysis tool for non-stationary data, but in many cases, the choice of the mother wavelet and basis set remains uncertain, particularly when dealing with physiological data. Furthermore, the possibility exists for combining information from numerous mother wavelets so as to exploit different features from the data. However, the combinatorics become daunting given the large number of basis sets that can be utilized. Recent work in evolutionary computation has produced a subset selection genetic algorithm specifically aimed at the discovery of small, high-performance, subsets from among a large pool of candidates. Our aim was to apply this algorithm to the task of locating subsets of packets from multiple mother wavelet decompositions to estimate cardiac output from chest wall motions while avoiding the computational cost of full signal reconstruction. We present experiments which show how a continuous assessment metric can be extracted from the wavelets coefficients, but the dual-objective nature of the algorithm (high accuracy with small feature sets) imposes a need to restrict the sensitivity of the continuous accuracy metric in order to achieve the small subset size desired. A possibly subtle tradeoff seems to be needed to meet the dual objectives.

关键词： Wavelet Transform Data Mining Genetic Algorithm

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Epigenetic Regulation Of Gene Expression In The Protozoan Parasite Entamoeba histolytica.

Epigenetic Regulation Of Gene Expression In The Protozoan Pa...

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12th International Congress of Protozoology

作者： Ankri Serge ohad Fisher Hala Harony Mona Abed Sabina Bernes Rama siman-tov. Department of Molecular Microbiology The Bruce Rappaport Faculty of Medicine TechnionP.O.B 9649 Haifa 31096 Israel Department of Molecular Microbiology The Bruce Rappaport Faculty of Medicine TechnionP.O.B 9649 Haifa 31096 Israel Department of Molecular Microbiology The Bruce Rappaport Faculty of Medicine TechnionP.O.B 9649 Haifa 31096 Israel Department of Molecular Microbiology The Bruce Rappaport Faculty of Medicine TechnionP.O.B 9649 Haifa 31096 Israel Department of Molecular Microbiology The Bruce Rappaport Faculty of Medicine TechnionP.O.B 9649 Haifa 31096 Israel Department of Molecular Microbiology The Bruce Rappaport Faculty of Medicine TechnionP.O.B 9649 Haifa 31096 Israel

＜正＞DNA methylation is an epigenetic modification that occurs in a wide range of prokaryotic and eukaryotic organisms. DNA methylation is an important mechanism of regulation of genomic functions such as differential control of gene expression. Our knowledge about the relevance of DNA methylation in the biology of protozoan organisms is scanty. We identified by immunodetection the presence of 5-methylated cytosine （m5C） in the parasite Entamoeba histolytica. The synthesis of m5C is catalyzed by a cytosine-5 DNA methyltransferase （Ehmeth） that belongs to the Dnmt2 proteins family. The biological

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