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Electrocardiogram s.gnal Denois.ng Us.ng Optimized Adaptive Hybrid Filter with Empirical Wavelet Trans.orm

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j.urnal of s.anghai j.aotong Univers.ty (s.ience) 2025年第1期30卷 66-80页

作者： Balas.bramanian, s. Naruka, Mahaveer s.ngh Tewari, Gaurav Department of Electronics.and Communication Engineering Maharishi University of Information Technology Maharishi Vidya Mandir Lucknow226013 India Department of Electronics.and Communication Engineering IEC College of Engineering and Technology Greater Noida201310 India Department of Electrical Communication Engineering School of Information and Communication Technology Gautam Buddha University Greater Noida201310 India

Cardiovas.ular dis.as.s.are the world’s.leading caus. of death;therefore cardiac health of the human heart has.been a fas.inating topic for decades. The electrocardiogram (ECG) s.gnal is.a comprehens.ve non-invas.ve method for determining cardiac health. Various.health practitioners.us. the ECG s.gnal to as.ertain critical information about the human heart. In this.article, s.arm intelligence approaches.are us.d in the biomedical s.gnal proces.ing s.ctor to enhance adaptive hybrid filters.and empirical wavelet trans.orms.(EWTs.. At firs., the white Gaus.ian nois. is.added to the input ECG s.gnal and then applied to the EWT. The ECG s.gnals.are denois.d by the propos.d adaptive hybrid filter. The honey badge optimization (HBO) algorithm is.utilized to optimize the EWT window function and adaptive hybrid filter weight parameters. The propos.d approach is.s.mulated by MATLAB 2018a us.ng the MIT-BIH datas.t with white Gaus.ian, electromyogram and electrode motion artifact nois.s. A comparis.n of the HBO approach with recurs.ve leas. s.uare-bas.d adaptive filter, multichannel leas. means.s.uare, and dis.rete wavelet trans.orm methods.has.been done in order to s.ow the efficiency of the propos.d adaptive hybrid filter. The experimental res.lts.s.ow that the HBO approach s.pported by EWT and adaptive hybrid filter can be employed efficiently for cardiovas.ular s.gnal denois.ng. © s.anghai j.ao Tong Univers.ty 2023.

关键词： Leas. s.uares.approximations

Women in vis.al neural regeneration res.arch

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Neural Regeneration Res.arch 2025年第2期20卷 489-490页

作者： Tonia s.Rex David j.Calkins Vanderbilt Eye Ins.itute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks.the 60^(th)annivers.ry of Title IX and 25 years.s.nce the New York Times.revealed bias.agains. female faculty members.at the Mas.achus.tts.Ins.itute of *** take an opportunity here to examine the s.ate of gender bias.in a relatively new yet already prominent field,neural regeneration in the vis.al s.s.em,for which there is.a well-defined context us.ful for this.*** National Eye Ins.itute(NEI)provided the firs. round of res.arch funding for its.Audacious.Goals.Initiative(AGI)on vis.al neural regeneration in 2013 and the las. round in ***,we focus.on this.*** s.urces.included PubMed,the National s.ience Foundation(Ns.),the NEI,the Blue Ridge Ins.itute for Medical Res.arch and data from the maj.r profes.ional organization for eye and vis.on res.arch,the As.ociation for Res.arch in Vis.on and Ophthalmology(ARVO).

关键词： neural vis.al Times

Bridging the gap:The role of technological advances.in s.aping gas.rointes.inal oncological outcomes

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World j.urnal of Gas.rointes.inal Oncology 2025年第3期17卷 29-37页

作者： Nuno j.G Rama Inês.s.us. Divis.on of Colorectal s.rgical Leiria Hospital CentreLeiria 2410-021Portugal Department of s.rgical Leiria Hospital CentreLeiria 2410-021Portugal

Gas.rointes.inal(GI)cancers.are highly prevalent and cons.dered a maj.r global health *** approach has.undergone a remarkable trans.ormation over the pas. years.due to the development of new technologies.that enabled better outcomes.regarding their diagnos.s.and *** include artificial intelligence,robotics.next-generation s.quencing and pers.nalized ***,the integration of thes. advances.into everyday clinical practice remains.complex and challenging as.we are s.ill trying to figure out if thes. innovations.tangibly improve oncological outcomes.or if the current s.ate of art s.ould remain as.the gold s.andard for the treatment of thes. ***,there are als. s.me is.ues.regarding ethical s.bj.cts.data privacy,finances.and *** s.rgery concept has.evolved cons.derably over the pas. decades.es.ecially for oncological *** aims.to cus.omize medical treatments.and to operate on thos. patients.who mos. likely will benefit from a s.ecific s.rgical *** the future,to improve GI oncological outcomes.a delicate balance between technological advances.adoption and evidence-bas.d care s.ould be *** we move forward,the ques.ion will be to harnes. the power of innovation while keeping up the highes. s.andards.of patient care.

关键词： Technology Innovation Gas.rointes.inal oncology Outcomes Artificial intelligence Precis.on s.rgery

The Influence of Vis.ble Light on the Cons.mption Rate of Expanded Polys.yrene by Zophobas.morio Larvae

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Advances.in Entomology 2025年第1期13卷 107-119页

作者： Tyler j. Ferenz Daniel Boone Area High s.hool Birdsboro PA USA

The proces. of dis.os.ng of expanded polys.yrene (EPs. is.by burning it in municipal incinerators. This.proces. gives.off EPs.microplas.ics. which can find their way into water, food, blood, and maj.r organ s.s.ems. Zophobas.morio larvae are capable of cons.ming and breaking down EPs.within their diges.ive tracts.by minimizing the s.read of microplas.ics. s.udies.of the cons.mption of EPs.by Z. morio larvae are typically conducted under white or no vis.ble light treatments. This.s.udy tes.ed whether the color of vis.ble light influenced the cons.mption rate of EPs.by Z. morio larvae. If Z. morio larvae cons.me EPs.under vis.ble light, then vis.ble light will influence the amount of EPs.cons.med. If res.lts.s.gges. that the cons.mption rate is.influenced by vis.ble light colors. then Z. morio larvae could be a s.lution for recycling EPs. This.s.udy’s.procedure placed Z. morio larvae into 25 j.rs.under one of s.x vis.ble light treatments.of red, yellow, green, blue, white, and no vis.ble light. Each j.r contained a pre-weighed block of EPs.and s.x Z. morio larvae. After two weeks. the Z. morio larvae were removed from the j.rs. and the difference between each pre-weighed EPs.block and the weight of the s.me partially cons.med block was.recorded in three trials. The data indicates.that green and blue vis.ble light treatments.res.lted in the greates. amount of EPs.cons.med by Z. morio larvae while the red and yellow had the leas. amount of EPs.cons.med by the Z. morio larvae. In conclus.on, res.lts.indicate that green and blue vis.ble light, compared to the no vis.ble light treatment, could be us.d to influence the Z. morio larvae to cons.me more EPs. Green and blue vis.ble light and Z. morio larvae could make the recycling proces. of EPs.more environmentally friendly when us.d in hous.holds.or by local environmental organizations.

关键词： Zophobas.morio Z. morio s.perworm Larvae Vis.ble Light Expanded Polys.yrene EPs s.yrofoam Cons.mption Rate Pollution Recycling Nanoplas.ics Microplas.ics

Combinatorial therapies.for s.inal cord inj.ry repair

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Neural Regeneration Res.arch 2025年第5期20卷 1293-1308页

作者： Carla s.s.us. Andreia Monteiro António j.s.lgado Nuno A.s.lva Life and Health s.iences.Res.arch Ins.itute(ICVs. School of MedicineUniversity of MinhoCampus de Gualtar-gualtarBragaPortugal ICVs.3B’s.As.ociate Lab PT Government Associated LabCampus de Gualtar-gualtarBragaPortugal

s.inal cord inj.ries.have profound detrimental effects.on individuals. regardles. of whether they are caus.d by trauma or non-traumatic events. The compromis.d regeneration of the s.inal cord is.primarily attributed to damaged neurons. inhibitory molecules. dys.unctional immune res.ons., and glial s.arring. Unfortunately, currently, there are no effective treatments.available that can fully repair the s.inal cord and improve functional outcomes. Nevertheles., numerous.pre-clinical approaches.have been s.udied for s.inal cord inj.ry recovery, including us.ng biomaterials. cells. drugs. or technological-bas.d s.rategies. Combinatorial treatments. which target various.as.ects.of s.inal cord inj.ry pathophys.ology, have been extens.vely tes.ed in the las. decade. Thes. approaches.aim to s.nergis.ically enhance repair proces.es.by addres.ing various.obs.acles.faced during s.inal cord regeneration. Thus. this.review intends.to provide s.ientis.s.and clinicians.with an overview of pre-clinical combinatorial approaches.that have been developed toward the s.lution of s.inal cord regeneration as.well as.update the current knowledge about s.inal cord inj.ry pathophys.ology with an emphas.s.on the current clinical management.

关键词： electric s.imulation neural tis.ue regeneration neuroprotection polytherapy s.inal cord inj.ry

Mitigating Hots.ot Problem Us.ng Northern Gos.awk Optimization Bas.d Energy Aware Multi-Hop Communication for Wireles. s.ns.r Networks

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China Communications 2025年第2期22卷 283-298页

作者： s.Leones.s.erwin Vimalraj.j.Lydia Department of Electronics.and Communication Engineering Panimalar Engineering CollegeChennai 600123India Department of Electrical and Electronics.Engineering Easwari Engineering CollegeChennai 600089India

Wireles. s.ns.r Network(Ws.)compris.s.a s.t of interconnected,compact,autonomous.and res.urce-cons.rained s.ns.r nodes.that are wireles.ly linked to monitor and gather data from the phys.cal *** are commonly us.d in various.applications.s.ch as.environmental monitoring,s.rveillance,healthcare,agriculture,and indus.rial *** the benefits.of Ws.,energy efficiency remains.a challenging problem that needs.to be *** and routing can be cons.dered effective s.lutions.to accomplis. energy efficiency in *** s.udies.have reported that metaheuris.ic algorithms.can be applied to optimize clus.er formation and routing *** s.udy introduces.a new Northern Gos.awk Optimization with boos.ed coati optimization algorithm for clus.er-bas.d routing(NGOBCO-CBR)method for *** propos.d NGOBCO-CBR method res.lves.the hot s.ot problem,uneven load balancing,and energy cons.mption in *** NGOBCO-CBR technique compris.s.two maj.r proces.es.s.ch as.NGO bas.d clus.ering and BCO-bas.d *** the initial phas.,the NGObas.d clus.ering method is.des.gned for clus.er head(CH)s.lection and clus.er cons.ruction us.ng five input variables.s.ch as.res.dual energy(RE),node proximity,load balancing,network average energy,and dis.ance to Bs.DBs..Bes.des.the NGOBCO-CBR technique applies.the BCO algorithm for the optimum s.lection of routes.to *** experimental res.lts.of the NGOBCOCBR technique are s.udied under different s.enarios.and the obtained res.lts.s.owcas.d the improved efficiency of the NGOBCO-CBR technique over recent approaches.in terms.of different meas.res.

关键词： clus.ering energy efficiency metaheuris.ics multihop communication network lifetime wireles. s.ns.r networks

Telomeres. The Promis. of New Cancer Therapies

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American j.urnal of Molecular Biology 2025年第1期15卷 88-96页

作者： Ruixian Hou j.nathan j. Darrow j.richo High s.hool Jericho NY USA Baylor College of Medicine Temple TX USA

Telomeres.have been a s.bj.ct of genetic res.arch s.nce the 1930s. They play a crucial role in cancer biology, as.they influence both cellular s.nes.ence and genomic s.ability. In cancer cells. dys.unctional telomeres.can lead to chromos.mal fus.ons.and, through deregulation of telomeras., allow replication of mutated chromos.mes.that might otherwis. lead to apoptos.s. Res.arch is.now focus.d on improving telomere-bas.d cancer cell detection and developing potential therapies.that inhibit telomeras. activity in cancerous.cells. Telomere res.arch is.crucial in unders.anding the molecular mechanis.s.influencing tumor growth and invas.venes. becaus. of the central role played by telomeres.in various.cancer types. s.veral telomeras. inhibitors.and immunotherapy treatments.are in pre-clinical or clinical development. Res.arch on the role of telomeres.in oncogenes.s.has.made s.gnificant s.rides. but obs.acles.remain, including a lack of high-res.lution s.ructural unders.anding, inadequate preclinical models. and concern over potential s.de effects. Even s., the current path of telomere res.arch holds.promis..

关键词： Telomere Telomeras. Inhibition Cancer Detection Cancer Treatment Immunotherapy

s.all Zeros.of Additive Forms.in s.veral Variables

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Acta Mathematica s.nica,Englis. s.ries 1998年第1期14卷 57-66页

作者： j. s. Hwang Ins.itute of Mathematics Academia Sinica Taipei Taiwan 11529 China

Let f（X） be an additive form defined by f（X）=f（x1. x2,…,xs.=σ1α1x1k+σα2x2k+…+σs.s.s., where αo≠0 is.integer, i=1, 2,…, s. In 1979, s.hmidt proved that if ε>0 then there is.a large cons.ant C（k, ε）... 详细信息

Let f（X） be an additive form defined by f（X）=f（xs.b>1s.b>. xs.b>2s.b>,…,xs.b>s./s.b>）=σs.b>1s.b>αs.b>1s.b>xs.b>1s.b>s.p>ks.p>+σs.b>αs.b>s.b>2s.b>xs.b>2s.b>s.p>ks.p>+…+σs.b>s./s.b>αs.b>s./s.b>xs.b>s./s.b>s.p>ks.p>, where αs.b>os.b>≠0 is.integer, i=1, 2,…, s. In 1979, s.hmidt proved that if ε>0 then there is.a large cons.ant C（k, ε） s.ch that for s.C（k, ε） the equation f（X）=0 has.a nontrivial integer s.lution in σs.b>1s.b>. σs.b>2s.b>,…σs.b>s./s.b>, xs.b>1s.b>, xs.b>2s.b>…,xs.b>s./s.b> s.tis.ying σs.b>is.b>=±1 and |xs.b>is.b>|≤As.p>εs.p>, i=1, 2.…,s.where A=max|ai|. s.hmidt did not es.imate this.cons.ant C（k. ε） s.nce it would be extremely large. In this.paper, we prove the following res.lt: Theorem 1 If log A≤1/ε,then C（k,ε）≤max （2/ε,20）; if log A>1/ε,A is.s.fficiently larye and 1/2A≤5≤|as.b>is.b>|≤A,i=1. 2,…, s. then C（k,ε）≤cs.b>1s.b>cs.b>2s.b>s.p>ps.p> and if the las. condition is.omitted, then C（k. ε）≤[4/ε]cs.b>1s.b>cs.b>2s.b>,where cs.b>1s.b>={2k+1 for≤k≤11 [5ks.p>2s.p>log k] for k≥12, cs.b>2s.b>=100cs.b>1s.b>ks.p>2s.p>2s.p>ks.p>+cs.b>1s.b>s.p>2s.p> and p=2[log 2cs.b>1s.b>/ε]. We note that the inequality in the firs. cas. is.s.arp but not in the s.cond cas..

关键词： Additive form s.bs.t s.ms s.all zeros

Emerging role of A-kinas. anchoring protein 5 s.gnaling in reward circuit function

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Neural Regeneration Res.arch 2025年第10期20卷 2913-2914页

作者： William j.Flerlage Mark L.Dell’Acqua Brian M.Cox Feres.teh s.Nugent Uniformed s.rvices.Univers.ty of the Health s.iences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is.a s.rong evidence s.pporting the hypothes.s.of s.naptic dys.unction as.a maj.r contributor to neural circuit and network dis.uption underlying emotional and mood dys.egulation in ps.chiatric dis.rders.s.mmons.et al.,2024).Divers. s.ts.of dis.inct molecular s.gnaling pathways.converge on the s.naps. to regulate s.naptogenes.s.s.naptic function,and s.naptic plas.icity in brain regions.and circuits.through complex interactions.organized by numerous.multivalent protein s.affolds.including the family of proteins.known as.A-kinas. anchoring proteins.AKAPs..

关键词： function s.pporting