检索结果-南通市图书馆

Multi-institutional analysis of cervical esophageal carcinoma patients treated with definitive chemoradiotherapy: TROD 01-005 study

引用

Oncology Research 2023年第3期31卷 299-306页

作者： ozan cem guler EZGI OYMAK GOZDE YAZICI OZLEM OZKAYA AKAGUNDUZ OGUZ CETINAYAK PETEK ERPOLAT ATIL AKSOY MURSEL DUZOVA BERNA AKKUS YILDIRIM MERAL KURT EMINE CANYILMAZ guler YAVAS SERAP AKYUREK DIDEM COLPAN OKSUZ ESRA KAYTAN SAGLAM OMUR KARAKOYUN CELIK ENIS OZYAR MUSTAFA CENGIZ cem ONAL Department of Radiation Oncology Faculty of MedicineBaskent UniversityAdana Dr.Turgut Noyan Research and Treatment CenterAdanaTurkey Radiation Oncology Unit Iskenderun Gelisim HospitalHatayTurkey Department of Radiation Oncology Faculty of MedicineHacettepe UniversityAnkaraTurkey Department of Radiation Oncology Faculty of MedicineEge UniversityIzmirTurkey Department of Radiation Oncology Faculty of Medicine9 Eylul UniversityIzmirTurkey Department of Radiation Oncology Faculty of MedicineGazi UniversityAnkaraTurkey Department of Radiation Oncology Faculty of MedicineAkdeniz UniversityAntalyaTurkey Department of Radiation Oncology Faculty of MedicineSelcuk UniversityKonyaTurkey Radiation Oncology Unit Prof.Dr.Cemil Tascioglu HospitalİstanbulTurkey Department of Radiation Oncology Faculty of MedicineUludag UniversityBursaTurkey Department of Radiation Oncology Faculty of MedicineKaradeniz Technical UniversityTrabzonTurkey Department of Radiation Oncology Faculty of MedicineBaskent UniversityAnkaraTurkey Department of Radiation Oncology Faculty of MedicineAnkara UniversityAnkaraTurkey Department of Radiation Oncology Faculty of MedicineIstanbul University CerrahpasaIstanbulTurkey Radiation Oncology Unit Memorial Sisli HospitalIstanbulTurkey Department of Radiation Oncology Faculty of MedicineCelal Bayar UniversityManisaTurkey Department of Radiation Oncology Acibadem University Maslak HospitalIstanbulTurkey

The aim of this study was to examine the prognostic factors and treatment outcomes of cervical esophageal carcinoma(CEC)patients who underwent definitive chemoradiotherapy(CRT).The clinical data of 175 biopsyconfirmed CEC patients treated with definitive CRT between April 2005 and September 2021 were retrospectively *** prognostic factors predicting overall survival(OS),progression-free survival(PFS),and local recurrence-free survival(LRFS)were assessed in uni-and multivariable *** median age of the entire cohort was 56 years(range:26–87 years).All patients received definitive radiotherapy with a median total dose of 60 Gy,and 52%of the patients received cisplatin-based concurrent *** 2-year OS,PFS,and LRFS rates were 58.8%,46.9%,and 52.4%,respectively,with a median follow-up duration of 41.6 ***’performance status,clinical nodal stage,tumor size,and treatment response were significant prognostic factors for OS,PFS,and LRFS in univariate ***-complete treatment response was an independent predictor for poor OS(HR=4.41,95%CI,2.78–7.00,p<0.001)and PFS(HR=4.28,95%CI,2.79–6.58,p<0.001),whereas poor performance score was a predictor for worse LRFS(HR=1.83,95%CI,1.12–2.98,p=0.02)in multivariable ***-two patients(29.7%)experienced grade II or higher *** this multicenter study,we demonstrated that definitive CRT is a safe and effective treatment for patients with *** radiation doses were found to have no effect on treatment outcomes,but a better response to treatment and a better patient performance status did.

关键词： Esophageal cancer Chemoradiotherapy Radiotherapy Local control Toxicity Survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Vascular endothelial growth factor gene polymorphisms in age-related macular degeneration in a Turkish population

引用

International Journal of Ophthalmology(English edition) 2014年第5期7卷 773-777页

作者： Yunus Bulgu Gokhan ozan Cetin Vildan Caner Ebru Nevin Cetin Volkan Yaylali cem Yildirim Department of Ophthalmology School of MedicinePamukkale University Department of Medical Genetics School of MedicinePamukkale University Department of Medical Biology School of MedicinePamukkale University

AIM:To assess the association between age-related macular degeneration(AMD) and three single nucleotide polymorphisms(SNPS) related to the vascular endothelial growth factor(VEGF) ***:The patients who were diagnosed with AMD were included in this prospective study. Three SNPs(rs1413711, rs2146323, and rs3025033) of the VEGF gene were genotyped by real-time polymerase chain reaction in the genomic DNA isolated from peripheral blood samples of the 82 patients and 80 ***:The genotype frequencies of rs1413711 and rs2146323 were not significantly different between the study group and the control group(P =0.072 and P =0.058).However, there was a significant difference in the genotype frequencies of these SNPs between the wet type AMD and dry type AMD(P =0.005 and P =0.010,respectively). One of the SNPs(rs1413711) was also found to be associated with the severity of AMD(P =0.001)with significant genotype distribution between early,intermediate, and advanced stages of the disease. The ancestral alleles were protective for both SNPs while the polymorphic alleles increased the risk for dry ***:VEGF SNPs rs1413711 and rs2146323 polymorphisms are significantly associated with AMD subtypes in our population.

关键词： age-related macular degeneration vascular endothelial growth factor single nucleotide polymorphism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A new technique for the reconstruction of complex portal vein anomalies in right lobe living liver donors

引用

Hepatobiliary & Pancreatic Diseases International 2012年第4期11卷 438-441页

作者： Onur Yaprak Necdet guler N cem Balci Murat Dayangac Tolga Demirbas Refik Killi Yaman Tokat Yildiray Yuzer Hepatobiliary and Organ Transplant Center Florence Nightingale HospitalIstanbulTurkey Department of Radiology Bilim UniversityIstanbulTurkey

Living donor liver right lobe transplantation using donors with variation of the right sectorial portal vein is considered a challenging procedure in terms of the donor’s safety and the complexity of reconstruction in the *** describe an innovative technique to reconstruct double portal vein orifices via a deceased donor iliac vein *** postoperative course of the recipient was *** ultrasound on the fourth postoperative month revealed equivalent flow in both portal vein *** of double right portal vein branches using a cryopreserved iliac vein is a valuable technique for utilizing right lobe grafts with challenging portal vein anatomy.

关键词： liver transplantation living donor portal vein variations venous plasty

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

钢板剪力墙结构的自振周期

引用

钢结构(中英文) 2010年第12期 80-81页

作者： cem Topkaya Can ozan Kurban

在大多建筑抗震规范中,都是通过结构自振周期计算设计地震加速度。设计规范给出了结构基本自振周期的经验公式。研究了一系列沿高度方向属性不变的钢板剪力墙结构。采用三维几何线性有限元分析确定这些结构的基本自振周期,并与规范给出... 详细信息

在大多建筑抗震规范中,都是通过结构自振周期计算设计地震加速度。设计规范给出了结构基本自振周期的经验公式。研究了一系列沿高度方向属性不变的钢板剪力墙结构。采用三维几何线性有限元分析确定这些结构的基本自振周期,并与规范给出的经验值进行比较,结果表明,经验公式并不准确。提出一个简化方法用于估算结构的基本自振周期,该方法将钢板剪力墙看成竖向悬臂结构,这样就可简化求解过程。考虑剪力墙的抗剪和抗弯刚度,在框架剪力墙结构中,这种简化方法可以进一步应用到具有钢板墙和抗弯框架的双系统结构中。将采用此方法计算的自振周期与有限元分析结果比较,可知两者非常吻合。研究了几何非线性和材料非线性对基本周期的影响。在不同的侧移水平下,计算钢板墙的基本周期。基于数值分析,给出由填充板屈曲和屈服带来的周期增大值。

关键词：钢板剪力墙自振周期有限元周期增大简化公式

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：