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Treatment of superficial corneal opacities with corneal stromal lenticule obtained through SMILE surgery

International Journal of Ophthalmology(English edition) 2024年第12期17卷 2221-2228页

作者： Shi-Si Hu Hui Ding Xu-Yun Meng Bo-Wen ouyang Zhen-Duo Yang Xiao-Dan chen xing-Wu Zhong Hainan Eye Hospital and Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityHaikou 570311Hainan ProvinceChina State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangzhou 510060Guangdong ProvinceChina

AIM:To evaluate the clinical efficacy and feasibility of superficial corneal opacities treated by excimer laser phototherapeutic keratectomy(PTK)combined with small incision lenticule extraction(SMILE)-derived corneal stromal lenticule ***:A retrospective interventional case series of nine patients aged 12-59y with superficial corneal opacity caused by different pathologies who underwent standardized PTK combined with SMILE-derived corneal stromal lenticule transplantation was *** patches were fixed with fibrin *** patients underwent pre-and post-operative clinical assessments at different times for up to *** lamp microscopy,corneal density,uncorrected distance visual acuity(UDVA),corrected distance visual acuity(CDVA),and anterior segment optical coherence tomography(AS-OCT)were ***:The patients’mean age was 36.00±5.80(12-59)*** eyes(77.8%)gained UDVA and CDVA at the last measurement compared to their preoperative *** densities of the total cornea,the total anterior corneal layer,and the anterior corneal layers of 0-2 and 2-6 mm decreased significantly by 12.4%,27.5%,46.7%,and 32.8%,*** human allogeneic transplantation,the implanted lenticules of all eyes were clearly visible by AS-OCT and remained transparent without displacement or graft *** thickness of the central cornea and corneal lenticule transplants were stable throughout the entire postoperative *** case experienced the postoperative complication of delayed corneal epithelial ***:PTK combined with SMILE-derived corneal lenticule transplantation improves long-term visual ***,it is a new,safe,and effective method for treating superficial corneal opacity.

关键词： corneal opacity corneal lenticule transplant phototherapeutic keratectomy

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Differences in clinical and genetic characteristics between early-and late-onset narcolepsy in a Han Chinese cohort

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Neural Regeneration Research 2020年第10期15卷 1887-1893页

作者： Hui ouyang Fang Han Ze-chen Zhou Jun Zhang Department of Clinical Neurology Peking University People’s HospitalBeijingChina Department of Clinical Pulmonology Peking University People’s HospitalBeijingChina Department of Epidemiology and Biostatistics School of Public HealthPeking University Health Science CenterBeijingChina

Early-and late-onset narcolepsy constitutes two distinct diagnostic ***,it is not clear whether symptomology and genetic risk factors differ between early-and late-onset *** study compared clinical data and single-nucleotide polymorphisms(SNPs)between early-and late-onset patients in a large cohort of 899 Han Chinese narcolepsy ***,cerebrospinal fluid,and clinical data were prospectively collected from patients,and patients were genotyped for 40 previously reported narcolepsy risk-conferring *** risk scores(GRSs),associations of five different sets of SNPs(GRS1–GRS5)with early-and late-onset narcolepsy,were evaluated using logistic regression and receiver operating characteristic *** sleep latency was significantly shorter in early-onset cases than in late-onset *** severity was greater among late-onset patients,with higher rates of sleep paralysis,hypnagogic hallucinations,health-related quality of life impairment,and concurrent presentation with four or more *** levels did not differ significantly between early-and late-onset *** rs3181077(CCR1/CCR3)and rs9274477(HLA-DQB1)were more prevalent among early-onset *** GRS1(26 SNPs;OR=1.513,95%CI:0.893–2.585;P<0.05)and GRS5(6 SNPs;OR=1.893,95%CI:1.204–2.993;P<0.05)were associated with early-onset narcolepsy,with areas under the receiver operating characteristic curves of 0.731 and 0.732,*** GRS1 nor GRS5 included SNPs in HLA *** results indicate that symptomology and genetic risk factors differ between early-and late-onset *** protocol was approved by the Institutional Review Board(IRB)Panels on Medical Human Subjects at Peking University People’s Hospital,China(approval *** 86)in October 2011.

关键词： case-control studies clinical features genetic association studies genetic load genetic loci genetic phenomena hypothalamic diseases precision medicine risk assessment single nucleotide polymorphism

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Exploring the thermal stability of lithium-ion cells via accelerating rate calorimetry:A review

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Journal of Energy Chemistry 2023年第6期81卷 543-573,I0012页

作者： Dongxu ouyang Mingyi chen Jingwen Weng Kuo Wang Jian Wang Zhirong Wang College of Safety Science and Engineering Nanjing Tech UniversityNanjing 211816JiangsuChina School of Environment and Safety Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei230026AnhuiChina

Given the importance of lithium-ion cell safety,a comprehensive review on the thermal stability of lithium-ion cells investigated by accelerating rate calorimetry(ARC),is provided in the present *** operating mechanism of ARC is discussed first,including the usage and the reaction *** that,the thermal stability of the cathode/anode materials at elevated temperatures is revealed by examining the impacts of some significant factors,i.e.,the lithium content,particle size,material density,lithium salt,solvent,additive,binder and initial heating temperature.A comparison of the common cathode materials indicates that the presence of Mn and polyanion could significantly enhance the thermal stability of cathode materials,while the doping of Al also helps to restrain the *** for their high capacity,some alloy materials demonstrate more competitive safety than traditional carbon anode ***,the thermal behaviors of full cells under abusive conditions are reviewed *** to the sensitivity of ARC to the kinetic parameters,a reaction kinetic modeling can be built on the basis of ARC profiles,to predict the thermal behaviors of cell components and ***,a shortcircuit modeling is exampled.

关键词： Accelerating rate calorimetry Electrode materials Full cells Safety Modeling

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High Efficiency Formamidinium-Cesium Perovskite-Based Radio-Photovoltaic Cells

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Energy & Environmental Materials 2024年第1期7卷 160-167页

作者： Runlong Gao Rui chen Pengying Wan Xiao ouyang Qiantao Lei Qi Deng Xinyu Guan Guangda Niu Jiang Tang Wei chen Zonghao Liu Xiaoping ouyang Linyue Liu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Northwest Institute of Nuclear TechnologyXi'an 710024China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China School of Microelectronics Xi'an Jiaotong UniversityXi'an 710049China Key Laboratory of Beam Technology of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China

Radio-photovoltaic cell is a micro nuclear battery for devices operating in extreme environments,which converts the decay energy of a radioisotope into electric energy by using a phosphor and a photovoltaic *** phosphors with high light yield and good environmental stability have been developed,but the performance of radio-photovoltaic cells remains far behind expectations in terms of power density and power conversion efficiency,because of the poor photoelectric conversion efficiency of traditional photovoltaic converters under low-light *** paper reports an radio-photovoltaic cell based on an intrinsically stable formamidinium-cesium perovskite photovoltaic converter exhibiting a wide light wavelength response from 300 to 800 nm,high open-circuit voltage(V_(oc)),and remarkable efficiency at low-light *** a He ions accelerator is adopted as a mimickedαradioisotope source with an equivalent activity of 0.83 mCi cm^(-2),the formamidinium-cesium perovskite radio-photovoltaic cell achieves a V_(oc)of 0.498 V,a short-circuit current(J_(sc))of 423.94 nA cm^(-2),and a remarkable power conversion efficiency of 0.886%,which is 6.6 times that of the Si reference radio-photovoltaic cell,as well as the highest among all radio-photovoltaic cells reported so *** work provides a theoretical basis for enhancing the performance of radio-photovoltaic cells.

关键词： formamidinium-cesium perovskite phosphor photovoltaic converter power conversion efficiency radio-photovoltaic cell

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Electrocatalytic and photocatalytic performance of noble metal doped monolayer MoS2 in the hydrogen evolution reaction: A first principles study

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Nano Materials Science 2021年第1期3卷 89-94页

作者： Zheng Zhang Kai chen Qiang Zhao Mei Huang Xiaoping ouyang Beijing Key Laboratory of Passive Safety Technology for Nuclear Energy North China Electric Power UniversityBeijing102206China School of Nuclear Science and Engineering North China Electric Power UniversityBeijing102206China Northwest Institute of Nuclear Technology Xi'an710024China School of Materials Science and Engineering Xiangtan UniversityXiangtan411105China

To maximize the catalytic performance of MoS_(2) in the hydrogen evolution reaction,we investigate the electrocatalytic and photocatalytic performance of monolayer MoS_(2) doped with noble metal(Ag,Au,Cu,Pd,and Pt)using first principles calculation combined with the climbing image nudged elastic band *** find the band gap of the monolayer MoS_(2) is reduced significantly by the noble metal doping,which is unfavorable to improving its photocatalytic *** optical absorption coefficient shows that the doping does not increase the ability of the monolayer MoS_(2) to absorb visible *** monolayer MoS_(2) doped with the noble metal is not a potential photocatalyst for the hydrogen evolution reaction because the band edge position of the conduction band minimum is lower than-4.44 eV,the reduction potential of H^(+)/H_(2).Fortunately,the band gap reduction increases the electron transport performance of the monolayer MoS_(2),and the activation energy of water splitting is greatly reduced by the noble metal doping,especially the Pt *** the whole,noble metal doping can enhance the electrocatalytic performance of the monolayer MoS_(2).

关键词： Electrocatalytic Monolayer MoS2 Noble metal doping Hydrogen evolution reaction First principles calculation

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Core–Shell Microfiber Encapsulation Enables Glycerol‑Free Cryopreservation of RBCs with High Hematocrit

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Nano-Micro Letters 2024年第1期16卷 35-54页

作者： Xianhui Qin Zhongrong chen Lingxiao Shen Huilan Liu Xilin ouyang Gang Zhao Department of Electronic Engineering and Information Science University of Science and Technology of ChinaHefei 230027People’s Republic of China School of Biomedical Engineering Anhui Medical UniversityHefei 230022People’s Republic of China Department of Blood Transfusion The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001People’s Republic of China The Fourth Medical Center Chinese PLA General HospitalBeijing 100089People’s Republic of China

Cryopreservation of red blood cells(RBCs)provides great potential benefits for providing transfusion timely in *** concentrations of glycerol(20%or 40%)are used for RBC cryopreservation in current clinical practice,which results in cytotoxicity and osmotic injuries that must be carefully ***,existing studies on the low-glycerol cryopreservation of RBCs still suffer from the bottleneck of low hematocrit levels,which require relatively large storage space and an extra concentration process before transfusion,making it inconvenient(time-consuming,and also may cause injury and sample lose)for clinical *** this end,we develop a novel method for the glycerol-free cryopreservation of human RBCs with a high final hematocrit by using trehalose as the sole cryoprotectant to dehydrate RBCs and using core–shell alginate hydrogel microfibers to enhance heat transfer during *** from previous studies,we achieve the cryopreservation of human RBCs at high hematocrit(>40%)with high recovery(up to 95%).Additionally,the washed RBCs post-cryopreserved are proved to maintain their morphology,mechanics,and functional *** may provide a nontoxic,high-efficiency,and glycerol-free approach for RBC cryopreservation,along with potential clinical transfusion benefits.

关键词： Cryopreservation Human red blood cells Core-shell microfibers Trehalose Hematocrit

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Simultaneous energy harvesting and tribological property improvement

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Friction 2021年第5期9卷 1275-1291页

作者： Xiaofan WANG Jiliang MO Huajiang ouyang Zaiyu XIANG Wei chen Zhongrong ZHOU Tribology Research Institute Southwest Jiaotong UniversityChengdu 610031China School of Engineering University of LiverpoolLiverpool L693GHUK

In this study,piezoelectric elements were added to a reciprocating friction test bench to harvest friction‐induced vibration *** such as vibration acceleration,noise,and voltage signals of the system were measured and *** results show that the piezoelectric elements can not only collect vibration energy but also suppress friction‐induced vibration noise(FIVN).Additionally,the wear of the friction interface was examined via optical microscopy(OM),scanning electron microscopy(SEM),and white‐light interferometry(WLI).The results show that the surface wear state improved because of the reduction of *** order to analyze the experimental results in detail and explain them reasonably,the experimental phenomena were simulated ***,a simplified two‐degree‐of‐freedom numerical model including the original system and the piezoelectric system was established to qualitatively describe the effects,dynamics,and tribological behaviors of the added piezoelectric elements to the original system.

关键词： piezoelectric friction‐induced vibration(FIV) energy harvester wear state contact

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Fine-Tuning of Structural Distortion and Magnetic Anisotropy by Organosulfonates in Octahedral Cobalt(Ⅱ)Complexes

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Chinese Journal of Chemistry 2022年第18期40卷 2193-2202页

作者： Dong Shao Fang-Xue Xu Lei Yin Hong-Qing Li Yu-chen Sun Zhong-Wen ouyang Zhen-xing Wang Yi-Quan Zhang Xin-Yi Wang State Key Laboratory of Coordination Chemistry Collaborative Innovation Center of Advanced MicrostructuresSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjingJiangsu210023 China Hubei Key Laboratory of Processing and Application of Catalytic Materials College of Chemistry and Chemical EngineeringHuanggang Normal UniversityHuanggangHubei438000 China Jiangsu Key Laboratory for NSLSCS School of Physical Science and TechnologyNanjing Normal UniversityNanjingJiangsu210097 China Wuhan National High Magnetic Field Centre Huazhong University of Science and TechnologyWuhanHubei430074 China

Precise modulation of the magnetic anisotropy of metal ions remains highly important for the development of high–performance single-molecule magnets(SMMs).We herein reported the synthetic,structural,spectral,magnetic,and computational studies on four mononuclear Co^(Ⅱ) complexes in a distorted octahedral *** change of the organosulfonate anions triggers significant modification of the distorted octahedral CoN6 coordination sphere,which enables us to tackle the influence of the structural distortion on the magnetic anisotropy in these *** measurements revealed that the four complexes possess easy–plane magnetic anisotropy with large and positive zero-field splitting parameters,which decrease with the increasing distortion of the pseudo–octahedral Co^(Ⅱ) coordination *** correlation was further confirmed by high–frequency/–field EPR(HF–EPR)spectra and theoretical *** magnetic susceptibility measurements indicate that these complexes both exhibit slow magnetic relaxation under an external dc field,indicating the field-induced single-ion magnets(SIMs)of the four *** results indicate that structural distortion plays an important role in the magnetic anisotropy of CoⅡcomplexes and should be carefully considered in the design of molecular complexes with high magnetic anisotropy.

关键词： Cobalt Solid-state structures Magnetic properties Single-molecule magnets /Magnetic anisotropy

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Feature Selection Using Tree Model and Classification Through Convolutional Neural Network for Structural Damage Detection

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Acta Mechanica Solida Sinica 2024年第3期37卷 498-518页

作者： Zihan Jin Jiqiao Zhang Qianpeng He Silang Zhu Tianlong ouyang Gongfa chen School of Civil and Transportation Engineering Guangdong University of TechnologyGuangzhou510006China Guangdong Tianxin Electric Power Engineering Testing Co. LtdGuangzhou510663China

Structural damage detection(SDD)remains highly challenging,due to the difficulty in selecting the optimal damage features from a vast amount of *** this study,a tree model-based method using decision tree and random forest was employed for feature selection of vibration response signals in *** datasets were obtained by numerical experiments and vibration experiments,*** features extracted using this method were input into a convolutional neural network to determine the location of structural *** indicated a 5%to 10%improvement in detection accuracy compared to using original datasets without feature selection,demonstrating the feasibility of this *** proposed method,based on tree model and classification,addresses the issue of extracting effective information from numerous vibration response signals in structural health monitoring.

关键词： Feature selection Structural damage detection Decision tree Random forest Convolutional neural network

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Positive unlabeled named entity recognition with multi-granularity linguistic information

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High Technology Letters 2021年第4期27卷 373-380页

作者： ouyang Xiaoye chen Shudong Wang Rong Institute of Microelectronics Chinese Academy of SciencesBeijing 100029P.R.China University of Chinese Academy of Sciences Beijing 100049P.R.China Key Laboratory of Space Object Measurement Department Beijing Institute of Tracking and Telecommunications TechnologyBeijing 100094P.R.China

The research on named entity recognition for label-few domain is becoming increasingly *** this paper,a novel algorithm,positive unlabeled named entity recognition(PUNER)with multi-granularity language information,is proposed,which combines positive unlabeled(PU)learning and deep learning to obtain the multi-granularity language information from a few labeled in-stances and many unlabeled instances to recognize named ***,PUNER selects reliable negative instances from unlabeled datasets,uses positive instances and a corresponding number of negative instances to train the PU learning classifier,and iterates continuously to label all unlabeled ***,a neural network-based architecture to implement the PU learning classifier is used,and comprehensive text semantics through multi-granular language information are obtained,which helps the classifier correctly recognize named *** tests of the PUNER are carried out on three multilingual NER datasets,which are CoNLL2003,CoNLL 2002 and SIGHAN Bakeoff *** results demonstrate the effectiveness of the proposed PUNER.

关键词： named entity recognition(NER) deep learning neural network positive-unla-beled learning label-few domain multi-granularity(PU)

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