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Frontiers of Environmental Science & Engineering 2023年第3期17卷 93-105页

作者： Ying xue Keke Xiao Xiang Wu mei Sun Yifei Liu Bei ou Jiakuan Yang School of Environmental Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China

This study systematically investigated the changes of amino acids as the composting process of food waste proceeded.It is found that the addition of 0.3 g/g total solids of food waste achieved the highest seed germination index of the product(268%).The microbial community results indicated that the abundance of amino acid metabolism sequences remained at high levels during the whole composting process.Proline was identified as the key amino acid related with the nutrient quality of product during the composting of food waste.Further plant germination and hydroponic experiments found,that compared with those without the addition of proline,the addition of 50 mg/L proline increased seed germination rate by 20%,increased shoot length by 3%,increased root biomass of seedlings by 82%,and increased leaf biomass of seedlings by 76%,respectively.Firmicutes,γ-Pseudomonadota,Chloroflexi and Planctomycetes were the key identified bacteria related with the increase of proline during the composting of food waste.Meanwhile,the enzymatic tests of the activities of superoxide dismutase,peroxidase and malondialdehyde indicated that proline did not cause oxidative damage on the growth of plants.This study provided novel insights into the changes of amino acids,microbial community,and enzymatic activities related with the nutrient quality of product during the composting of food waste.

关键词： Composting Food waste Amino acids Microbial community Enzymatic activity Nutrient quality

Association of chronic obstructive pulmonary disease with coronary artery disease

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Chinese Medical Journal 2013年第17期126卷 3205-3208页

作者： LIANG Bin-miao XU Zhi-bo YI Qun OU Xue-mei FENG Yu-lin Department of Respiratory Medicine West China Hospital of Sichuan University Chengdu Sichuan 610041 China Department of Respiratory Medicine No. 2 People's Hospital of Chengdu Chengdu Sichuan 610017 China

Background The relationship between chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) remains largely unknown. This study aimed to explore the association of COPD with CAD, especially with multi- vessel disease (VD). Methods The data of 354 patients who underwent multi-detector computed tomography (MDCT) for suspected CAD were analyzed. Luminal narrowing was defined as at least one lesion 50% or greater stenosis. The analysis of serum biochemistry profile and spirometrywere performed on all eligible patients, and the diagnosis of COPD was defined as the criteria of Global Initiative for Chronic Obstructive Lung Disease. Results Patients with CAD had a significantly higher complication of COPD than those without CAD (11.8% vs. 3.7%, P out COPD, those with COPD were more likely to have multi-VD, proportion of smoking and high C-reactive protein (CRP) (P <0.001). Multivariate Logistic regression analysis revealed that the multi-VD was significantly correlated with COPD (P=-0.012) and CRP (P=0.015). Conclusions There was a high complication of COPD in patients with CAD, and COPD may be a critical risk factor for CAD, especially for multi-VD. CAD and COPD were closely associated and the interplay of systemic inflammation might in part explain the relationship between them.

关键词：慢性阻塞性肺疾病冠状动脉疾病慢性阻塞性肺病 Logistic回归分析协会计算机断层扫描 C-反应蛋白 CAD

Synthesis and Spectroscopic Properties of Cyclotriphosphazenes Containing 6-(4-Hydroxyphenyl)-2,2'-bipyridine Side Groups

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Chemical Research in Chinese Universities 2007年第6期23卷 679-682页

作者： ZHANG Jun-feng GAN Xin OU Xue-mei FU Wen-fu College of Chemistry and Chemical Engineering Yunnan Normal University Kunming 650092 P. R. China Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100080 P. R. China

Two novel cyclotriphosphazene derivatives containing 6-(4-hydroxyphenyl)-2,2'-bipyridine(hopbp)side groups,N_3P_3(dobp)_2(hopbp)_2(1)and N_3P_3(dobp)(hopbp)_4(2)(dobp=2,2'-dioxybiphenyl),were synthesized and characterized.These compounds display strong fluorescent emission both in solution and in solid state.Their absorption and emission spectra are sensitive to proton:the addition of HBF4 to the methanol and dichloromethane solution(9∶1,volume ratio)of compound 1 led to a red-shift from 350 to 460 nm for the emission spectrum,and the process was also characterized by isosbestic points of absorption spectra at 267,287 and 313 nm.

关键词：二嘧啶合成质子光谱学

Advanced Chronic Obstructive Pulmonary Disease： Innovative and Integrated Management Approaches

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Chinese Medical Journal 2015年第21期128卷 2952-2959页

作者： Hai-Xia ZhOU Xue-mei ou Yong-Jiang Tang Lan Wang Yu-Lin Feng Department of Respiratory Medicine West China Hospital Sichuan University Chengdu Sichuan 610041 China

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and increasing.By the year 2020,COPD will be t... 详细信息

关键词：慢性阻塞性肺疾病晚期慢性阻塞性肺病管理创新呼吸系统疾病医疗保健系统社会负担

Research on the Anticorrosion Coating Under the Paved Layer for Highway Steel Box Bridge Deck

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Journal of China University of Mining and Technology 2006年第4期16卷 429-432页

作者： SHEN Cheng-jin MING Tu-zhang HU Guang-wei OU Xue-mei GEN ou School of Material Science ＆ Engineering China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China Jiangsu Provincial Communication Planning and Design Institute Nanjing Jiangsu 210005 China

The corrosion of the anticorrosion coating and the defects of the asphalt concrete paved layer have been investigated on long-span steel box bridge decks. The anticorrosion coating lies in the middle of two entirely different materials: a highway steel box bridge deck and a paved layer, which is used as anticorrosion and waterproof coating for the steel bridge deck. For our study, electrochemical corrosion and pull strength experiments have been selected for the investigation of the corrosion properties of inorganic zinc rich coating, epoxy zinc rich coating and arc sprayed zinc coating. The adhesive strength between the coatings and the panel, and the effect of the coating corrosion on the shear properties of the paved layers including cast asphalt, thermal asphalt mortar, epoxy asphalt and modified asphalt concrete have been investigated. The results show that the adhesive strength between the coatings and the bridge panel is controlled by the method of pre-processing rust removal. Coating by sandblasting has stronger adhesive strength than coating by shot peening. The results also reveal that shear strength of the paved layer is affected by the corrosion product of zinc coating. The arc sprayed zinc coating has stronger shear strength than zinc rich coalings.

关键词：金属材料钢合金防蚀性电气化学

Ultrasonic elastography in clinical quantitative assessment of fatty liver

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World Journal of Gastroenterology 2010年第37期16卷 4733-4737页

作者： Yin-Yan Li xue-mei Wang Yi-Xia Zhang Guo-Cheng ou Department of Ultrasonic Diagnosis the First Af��liated Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

AIM: To investigate the clinical application of ultrasonic elastography in quantitative assessment of fatty liver grading. METHODS: A total of 105 patients with fatty liver were divided into mild group (n = 46), moderate group (n = 39), and severe group (n = 20). Forty-five healthy individuals served as a normal control group. All patients who underwent routine ultrasound scan and further ultrasonic elastography were evaluated accordingly to the evaluation standards for ultrasonic elastography. The ratio of surface areas of blue region/total surface area in the desired region was measured. RESULTS: Ultrasonic elastography technique, in comparison to traditional ultrasound, had a rather high consistence in grading of fatty liver [κ value = (95.3%63.6%)/(1%-63.6%) = 0.87, P = 0.001]. The score of ultrasonic elastography increased with the severity of fatty liver with a sensitivity of 97.14% and a specificity of 91.11%. A significant difference was found in the ratio of surface areas of blue regions between different groups (P < 0.05).CONCLUSION: Ultrasonic elastography can be used in quantitative assessment of the severity of fatty liver.

关键词： Transient elastography Ultrasonic elastography evaluation Fatty liver Quantitative diagnosis Grading of fatty liver

Relationship between 6-minute walk test and pulmonary function test in stable chronic obstructive pulmonary disease with different severities

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Chinese Medical Journal 2012年第17期125卷 3053-3058页

作者： CHEN Hong LIANG Bin-miao TANG Yong-jiang XU Zhi-bo WANG Ke YI Qun OU Xue-mei FENG Yu-lin Department of Respiratory Medicine West China HospitalSichuan UniversityChengduSichuan 610041China Department of Respiratory Medicine Second People's Hospital of ChengduChengduSichuan 610017China

Background The relationship between the 6-minute walk test (6MWT) and pulmonary function test in stable chronic obstructive pulmonary disease (COPD) remains unclear. We evaluate the correlation of 6MWT and spirometric parameters in stable COPD with different severities. 6MWT data assessed included three variables: the 6-minute walk distance (6MWD), 6-minute walk work (6MWORK), and pulse oxygen desaturation rate (SPO2%). Methods 6MWT and pulmonary function test were assessed for 150 stable COPD patients with different severities. Means and standard deviations were calculated for the variables of interest. Analysis of variance was performed to compare means. Correlation coefficients were calculated for 6MWT data with the spirometric parameters and dyspnea Borg scale. Multiple stepwise regression analysis was used to screen pulmonary function-related predictors of 6MWT data. Results The three variables of 6MWT all varied as the severities of the disease. The 6MWD and 6MWORK both correlated with some spirometric parameters (positive or negative correlation; the absolute value of r ranging from 0.34 to 0.67; P our severities (t= -0.33, -0.34, -0.39, -0.53 respectively; P our severities (r=0.56, 0.57, 0.72, 0.81 respectively, P <0.05), and neither of them correlated with the SPO2%. The percent of predicted forced expiratory volume in 1 second (FEV1% predicted) and residual volume to total lung capacity ratio (RV/TLC) were predictors of the 6MWD, and the maximum voluntary ventilation (MW) was the predictor of the 6MWORK. Conclusions 6MWT correlated with the spirometric parameters in severe and very severe COPD patients. 6MWT may be used to monitor changes of pulmonary function in these patients.

关键词：慢性阻塞性肺疾病功能检测试验慢性阻塞性肺病多元逐步回归分析血氧饱和度功能参数评估方法

Oxygen Metabolism-induced Stress Response Underlies Heartbrain Interaction Governing Human Consciousness-breaking and Attention

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Neuroscience Bulletin 2022年第2期38卷 166-180页

作者： Xiao-Juan xue Rui Su Ze-Feng Li Xiao-ou Bu Peng Dang Si-Fang Yu Zhi-Xin Wang Dong-mei Chen Tong-Ao Zeng Ming Liu Hai-Lin Ma De-Long Zhang Key Laboratory of Brain Cognition and Education SciencesMinistry of EducationChinaSchool of PsychologyCenter for Studies of Psychological Applicationand Guangdong Key Laboratory of Mental Health and Cognitive ScienceSouth China Normal UniversityGuangzhou 510631China Plateau Brain Science Research Center South China Normal University/Tibet UniversityLhasa 850012China

Neuroscientists have emphasized visceral influences on consciousness and attention,but the potential neurophysiological pathways remain under exploration.Here,we found two neurophysiological pathways of heartbrain interaction based on the relationship between oxygen-transport by red blood cells(RBCs)and consciousness/attention.To this end,we collected a dataset based on the routine physical examination,the breaking continuous flash suppression(b-CFS)paradigm,and an attention network test(ANT)in 140 immigrants under the hypoxic Tibetan environment.We combined electroencephalography and multilevel mediation analysis to investigate the relationship between RBC properties and consciousness/attention.The results showed that RBC function,via two independent neurophysiological pathways,not only triggered interoceptive re-representations in the insula and awareness connected to orienting attention but also induced an immune response corresponding to consciousness and executive control.Importantly,consciousness played a fundamental role in executive function which might be associated with the level of perceived stress.These results indicated the important role of oxygen-transport in heart-brain interactions,in which the related stress response affected consciousness and executive control.The findings provide new insights into the neurophysiological schema of heartbrain interactions.

关键词： Heart-brain interaction Breaking continuous flash suppression Executive attention Stress response

A Novel De novo GATA-binding Protein 3 Mutation in a Patient with Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia Syndrome

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Chinese Medical Journal 2017年第11期130卷 1378-1380页

作者： xue-Ying Chu Yue-Peng Li Min Nie ou Wang Yan Jiang mei Li Wei-Bo Xia Xiao-Ping Xing Department of Endocrinology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 China

Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome, also called Barakat syndrome, is an autosomal dominant genetic disease caused by haploinsufficiency of the GATA-binding protein 3 (GATA3)... 详细信息

关键词： De novo Mutation GATA-binding Protein 3 Gene Hypoparathyroidism Sensorineural Deafness and Renal Dysplasia Syndrome

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“人民至上”——新中国文化建设的价值追求

中国井冈山干部学院学报 2019年第6期12卷 79-86页

作者：欧阳雪梅中国社会科学院当代中国研究所

社会主义文化建设是社会主义事业的重要组成部分。新中国70年来的文化建设,坚持和发展了马克思主义文化发展理念,以人民至上为价值宗旨,确立和坚持文化发展为了人民,文化发展依靠人民,文化发展成果由人民共享,文化建设以全面提高人的素... 详细信息

社会主义文化建设是社会主义事业的重要组成部分。新中国70年来的文化建设,坚持和发展了马克思主义文化发展理念,以人民至上为价值宗旨,确立和坚持文化发展为了人民,文化发展依靠人民,文化发展成果由人民共享,文化建设以全面提高人的素质为目标,解决了中国文化发展中的根本问题,让文化发展成果惠及全体人民,满足了人民过上美好生活的新期待,培养"富有创造力和全面发展的新社会的建设者",把握社会主义文化发展的正确方向,为新中国实现从站起来、富起来到强起来的伟大飞跃提供了重要支撑。

关键词：新中国文化建设价值追求人民性