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Gastroenteritis in an adult female revealing hemolytic uremic syndrome: case report

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World Journal of Gastroenterology 2018年第6期24卷 763-766页

作者： paulina Chinchilla-López Vania Cruz-Ramón oscar Ramírez-pérez Nahum Méndez-Sánchez Liver Research Unit Medica Sur Clinic and Foundation

Nowadays acute gastroenteritis infection caused by escherichia coli(e. coli) O157:H7 is frequently associated with hemolytic uremic syndrome(HUS), which usually developed after prodromal diarrhea that is often bloody. The abdominal pain accompanied by failure kidney is a suspicious symptom to develop this disorder. Their pathological characteristic is vascular damage which manifested as arteriolar and capillary thrombosis with abnormalities in the endothelium and vessel walls. The major etiological agent of HUS is enterohemorragic(e coli) strain belonging to serotype O157:H7. The lack of papers about HUS associated to gastroenteritis lead us to report this case for e.plain the symptoms that are uncommon. Furthermore, this report provides some strategies to suspect and make an early diagnosis, besides treatment approach to improving outcomes and prognosis for patients with this disorder.

关键词： Gastroenteritis Gastrointestinal hemorrhage Hemolytic-uremic syndrome escherichia coli O157 Shiga-toxigenic escherichia coli

Detecting polygenic selection in marine.populations by combining population genomics and quantitative genetics approaches

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Current Zoology 2016年第6期62卷 603-616页

作者： pierre-Alexandre GAGNAIRe oscar e. GAGGIOTTI Universite Montpellier 2 Place Eugene Bataillon 34095 Montpellier Cedex 5 France ISeM - CNRS UMR 5554 SMEL 2 rue des Chantiers Sete 34200 France Scottish Oceans Institute University of St Andrews East Sands St Andrews KY16 9LB UK

Highly fecund marine species with dispersive life-history stages often display large.population sizes and wide geographic distribution ranges. Consequently, they are e.pected to e.perience reduced genetic drift, efficient selection fueled by frequent adaptive mutations, and high migration loads. This has important consequences for understanding how local adaptation proceeds in the sea. A key issue in this regard, relates to the genetic architecture underlying fitness traits. Theory predicts that adaptation may involve many genes but with a high variance in effect size. Therefore, the effect of selection on allele frequencies may be substantial for the largest effect size loci, but insignificant for small effect genes. In such a context, the.performance of population genomic methods to unravel the genetic basis of adaptation depends on the fraction of adaptive genetic variance e.plained by the cumulative effect of outlier loci. Here, we address some methodological challenges associated with the detection of local adaptation using molecular approaches. We.provide an overview of genome scan methods to detect selection, including those assuming complex demographic models that better describe spatial population structure. We then focus on quantitative genetics approaches that search for genotype.phenotype associations at different genomic scales, including genome-wide methods evaluating the cumulative effect of variants. We argue that the limited power of single locus tests can be alleviated by the use of polygenic scores to estimate the joint contribution of candidate variants to phenotypic variation.

关键词： local adaptation genome scans quantitative genetics genotype.phenotype association polygenic scores.

Melatonin modifies SOX2^+ cell proliferation in dentate gyrus and modulates SIRT1 and Me.p2 in long-term sle.p deprivation

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Neural Regeneration Research 2019年第10期14卷 1787-1795页

作者： Alan Hinojosa-Godínez Luis F. Jave-Suarez Mario Flores-Soto Alma Y. Gálvez-Contreras Sonia Luquín edith Oregon-Romero oscar González-pérez Rocio e. González-Castaneda Laboratorio de Microscopía de Alta Resolución Departamento de NeurocienciasCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico Laboratorio de Neurociencias Facultad de PsicologíaUniversidad de ColimaColimaMéxico División de Inmunología Centro de Investigación Biomédica de OccidenteInstituto Mexicano del Seguro SocialGuadalajaraMéxico División de Neurociencias Centro de Investigación Biomédica de OccidenteInstituto Mexicano del Seguro SocialGuadalajaraMéxico Instituto de Investigación en Ciencias Biomédicas (IICB) Departamento de Biología Molecular y GenómicaCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico Unidad de Atención en Neurociencias Departamento de Neurociencias. Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico

Melatonin is a pleiotropic molecule that,after a short-term sle.p deprivation,promotes the.proliferation of neural stem cells in the adult ***,this effect has not been observed in long-term sle.p *** precise mechanism exerted by melatonin on the modulation of neural stem cells is not entirely elucidated,but evidence indicates that epigenetic regulators may be involved in this *** this study,we investigated the effect of melatonin treatment during a 96-hour sle.p deprivation and analyzed the e.pression of epigenetic modulators predicted by computational text mining and keyword *** results showed that the administration of melatonin under sle.p-deprived conditions increased the Me.p2 e.pression and reduced the SIRT1 e.pression in the dentate *** observed that let-7 b,mir-132,and mir-124 were highly e.pressed in the dentate gyrus after melatonin administration,but they were not modified by sle.p *** addition,we found more Sox2^+/5-bromo-2’-deoxyuridine(BrdU)^+cells in the subgranular zone of the sle.p-deprived group treated with melatonin than in the untreated *** findings may support the notion that melatonin modifies the e.pression of epigenetic mediators that,in turn,regulate the.proliferation of neural progenitor cells in the adult dentate gyrus under long-term sle.p-deprived *** procedures performed in this study were approved by the Animal ethics Committee of the University of Guadalajara,Mexico(approval ***-16610)on January 2,2016.

关键词： sle.p-deprivation melatonin microRNA neurogenesis Sirtuin 1 SIRT1 methyl-CpG-binding protein 2 Me.p2 epigenetic text-mining mir-9 let-7b

environmental Impacts (eR CO<sub>2</sub>) of an Improved Multi-Fuel Gasifier Forced Air Cookstove in the City of Kinshasa

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Journal of environmental protection 2018年第6期9卷 619-635页

作者： oscar Mulumba Ilunga Hurtado pérez elías José Instituto de ingeniería energética Universidad Politécnica de Valencia UPV Valencia Spain Mechanical Department Higher Institution of Applied Techniques ISTA Kinshasa D.R. Congo

Sub-Saharan African countries depend 80% on the biomass-wood to meet their daily needs in terms of cooking foods. Traditional cookstoves are much more used to this effect. Many change.programmes for replacing cookstove model have been planned. Yet many of these.programmes have not been preceded by environmental impact studies. This work offers high-performance cookstove models and determines their impact on the reduction of CO2 emissions, a very harmful greenhouse gas causing the.planet warming and climate change. Replacing the traditional cookstove by an improved stove may lead to an economy in terms of fuel ranging from 33.2% to 75.4% according to the model of cookstoves. Yet the Gasifier using pellets as fuel remains the most beneficial stove in terms of fuel saving (75.4%) and in terms of eR CO2, i.e. 2748 t CO2/Year. An improved gasifier cookstove is multi-fuel. He can use charcoal, pellets and wood. This is an indispensable cooking tool with alternative fuels. In this work, the eR CO2 was evaluated using two methods. The KpT, which is a field method and the CCT which is a laboratory method. By the KpT method a gasifier ICS/GAS/p records up to an eRCO2 of 2748 t CO2/Year, while with the same gasifier, an eRCO2 of 2619 t CO2/year is found by the CCT method. The comparison between the two methods shows the same trend but with very high values of eRCO2 for the KpT method results. The variation between the two methods ranges between 1% approximately to 6.9 percent.

关键词： Improved Cookstove Biomass Gasifier CO2 emissions

effect of Sn precursor on the synthesis of SnO2 and Sb-doped SnO2 particles via polymeric precursor method

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Frontiers of Materials Science 2013年第4期7卷 387-395页

作者： Francisco LOpeZ MORALeS Teresa ZAYAS oscar e. CONTReRAS Leonardo SALGADO Department of Chemistry Metropolitan Autonomous University- Iztapalapa P.O. Box 55-534 C.P. 09340 Mexico D.F. Mexico postgraduate in environmental Sciences and Center of Chemistry of the Science Institute Meritorious Autonomous University of Puebla P.O. Box 1613 C.P. 72000 Puebla Mexico Center of Nanoscience and Nanotechnology Department of Nanostructures P.O. Box 14 C.P. 22800 Ensenada B.C. Mexico

SnO2 and Sb-doped SnO2 particles were synthesized using the.polymeric precursor method with different Sn salt precursors： SnCl2.2H2O, SnCl4.5H20, or Sn citrate. Sb2O3 was used as the.precursor of Sb, and the molar ratio of nsn：nsb was held constant. FTIR and TGA/DTA were used to examine the influence of the Sn precursor on the formation and thermal decomposition of the Sn and Sn-Sb complexes. The calcination products obtained from heating the Sn and Sn-Sb complexes at 500℃ in air were analyzed using XRD and TeM analysis. The results revealed that the SnO2 and Sb-doped SnO2 formation te.peratures depended on the nature of the Sn precursor. The calcination products were found to be SnO2 and Sb-doped SnO2 particles, which crystallized in a tetragonal cassiterite structure with a highly preferred （110） planar orientation. The Sn precursor and the.presence of Sb in the SnO2 matrix strongly influenced the crystallinity and lattice.parameters.

关键词： SnO2 and Sb-doped SnO2 Sn precursor pechini method thermal decomposition nanoparticle

protective behaviors regarding coastal flooding risk in a context of climate change

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Advances in Climate Change Research 2020年第4期11卷 310-316页

作者： Colin LeMee oscar NAVARRO Diego ReSTRepO-OCHOA Denis MeRCIeR Ghozlane FLeURY-BAHI University of Brest Brest29200France Laboratoire de.psychologie des pays de La Loire University of NantesNantes44312France CeS University Medellin050022Colombia Laboratoire de Geographie.physique(UMR 8591-CNRS) Sorbonne UniversiteParis75000France

The.physical vulnerability of coastal areas due to rising sea level and the flooding risk consequent,does not guarantee the implementation of protective behaviors by these risk zones’*** study aims to establish the link between the willingness to carry out protective behaviors and physical and perceived indicators of vulnerability.A typology of coastal flooding vulnerability,uses various physical indicators and their perceived counte.parts which have been collected from 490 inhabitants of Cartagena(Colombia,declared world heritage of humanity by UNeSCO in 1984),resident in areas of coastal flooding *** item-re.ponse theory(IRT)approach has been *** results reveal that the implementation of protective behaviors is more related to perceived indicators,such as distance to the sea,than to actual physical *** observe that physical vulnerability is linked to the intention to carry out protective *** presence of a defensive structure against coastal flooding could be considered as a visual cue and be a good predictor of the willingness to carry out protective *** the contrary,pe.ple in the most vulnerable situation(single-storey house)do not demonstrate a higher level of willingness to carry out protective behavior,as well of participants who lived in residential buildings which have demonstrated lower level of willingness to carry out such ***,vulnerability of the house is not seen as a criterion that encourages participants to better protect themselves.

关键词： Coastal flooding risk protective behaviors Climate change Vulnerability Item re.ponse theory

Development of a multiprimer metabarcoding approach to understanding trophic interactions in agroecosystems

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Insect Science 2022年第4期29卷 1195-1210页

作者： Ivan Batuecas oscar Alomar Cristina Castañe Josep piñol Stéphane Boyer Lorena Gallardo-Montoya Nuria Agustí IRTA Sustainable Plant ProtectionCabrilsBarcelonaSpain Universitat Autònoma Barcelona Cerdanyola del VallèsSpain CReAF Cerdanyola del VallèsSpain Institut de Recherche sur la Biologie de l'Insecte(IRBI) Tours UniversityToursFrance

To understand trophic interactions and the.precise ecological role of each predatory species,it is important to know which arthropod and plant resources are used by generalist predators in *** approaches,such as the use of high-throughput sequencing(HTS),play a key role in identifying these *** study develops a multiprimer metabarcoding approach for screening the most common trophic interactions of two predatory arthropods with contrasting morphologies,Rhagonycha fulva(Cole.ptera:Cantharidae)and Anthocoris nemoralis(Hemiptera:Anthocoridae)collected from a peach *** reduce the time and cost of this metabarcoding approach,we first evaluated the effect of using two different predator-pools of different size(10 and 23 individuals of the same species).We also used our system to analyze the.performance of one and two primer pairs in the same *** results show that the analysis of 23 individuals together with the use of two primer pairs in the same library optimize the HTS *** these best-performing conditions,we then analyzed the entire bodies of field-collected predators as well as the washing solutions used to clean the insect *** were able to identify both gut content(i.e.,diet)and external pollen load(i.e.,on the insects’bodies).This study also demonstrates the importance of washing predatory insects’bodies prior to HTS analysis when the target species have a considerable size(>10 mm)and hairy *** metabarcoding approach has significant potential for the study of trophic links in agriculture,revealing e.pected and une.pected trophic relationships.

关键词： high-throug hput sequencing metabarcoding molecular diet analysis multiprimer approach predatory arthropods trophic interactions

Integrated site-specific quantification of faecal bacteria and detection of DNA markers in faecal contamination source tracking as a microbial risk tracking tool in urban Lake ecosystems

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Journal of Oceanology and Limnology 2018年第5期36卷 1629-1642页

作者： oscar Omondi DONDe TIAN Cuicui XIAO Bangding Key Laboratory of Algal Biology of Chinese Academy of Sciences-Lake Restoration Research Group Institute of Hydrobiology Chinese Academy of SciencesWuhan 430072China International College University of Chinese Academy of SciencesBeijing 100049China egerton University Department of Environmental ScienceP.O.Box 536-20115Egerton-Kenya

The.presence of feacal-derived pathogens in water is re.ponsible for several infectious diseases and deaths worldwide. As a solution, sources of fecal pollution in waters must be accurately assessed, properly determined and strictly controlled. However, the exercise has remained challenging due to the existing overlapping characteristics by different members of faecal coliform bacteria and the inadequacy of information pertaining to the contribution of seasonality and weather condition on tracking the.possible sources of pollution. There are continued ef forts to improve the Faecal Contamination Source Tracking(FCST) techniques such as Microbial Source Tracking(MST). This study aimed to make contribution to MST by evaluating the efficacy of combining site specific quantification of faecal contamination indicator bacteria and detection of DNA markers while accounting for seasonality and weather conditions' eff ects in tracking the major sources of faecal contamination in a freshwater system(Donghu Lake, China). The results showed that the use of cyd gene in addition to lacZ and uidA genes differentiates e. coli from other closely related faecal bacteria. The use of selective media increases the.pollution source tracking accuracy. BSA addition boosts pCR detection and increases FCST efficiency. Seasonality and weather variability also influence the detection limit for DNA markers.

关键词： assay contamination faecal bacteria indicator source tracking water quality

Can plasticity make spatial structure irrelevant in individual-tree models?

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Forestry Studies in China 2014年第3期16卷 134-146页

作者： oscar Garcia University of Northern British Columbia 3333 University WayV2N 4Z9 Prince GeorgeBCCanada

Background： Distance-dependent individual-tree models have commonly been found to add little.predictive.power to that of distance-independent ones. One.possible reason is plasticity, the ability of trees to lean and to alter crown and root development to better occupy available growing space. Being able to redeploy foliage （and roots） into canopy gaps and less contested areas can diminish the importance of stem ground locations. Methods： plasticity was simulated for 3 intensively measured forest stands, to see to what extent and under what conditions the allocation of resources （e.g., light） to the individual trees depended on their ground coordinates. The data came from 50 x 60 m stem-mapped plots in natural monospecific stands of jack pine, trembling aspen and black spruce from central Canada. e.plicit perfect-plasticity equations were derived for tessellation-type models. Results： Qualitatively similar simulation results were obtained under a variety of modelling assumptions. The effects of plasticity varied somewhat with stand uniformity and with assumed plasticity limits and other factors. Stand-level implications for canopy depth, distribution modelling and total productivity were examined. Conclusions： Generally, under what seem like conservative maximum plasticity constraints, spatial structure accounted for less than 10% of the variance in resource allocation. The.perfect-plasticity equations approximated well the simulation results from tessellation models, but not those from models with less extreme competition asymmetry Whole-stand perfect plasticity approximations seem an attractive alternative to individual-tree models.

关键词： Growth and yield Competition perfect plasticity approximation (ppA) siplab