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作者： orlando M. VALAREZO RIVERA 山东大学

学位级别：硕士

With the increase of high renewable energy penetration level,a large amount of reserve is required and the reserve resource would become more and more ***,it is urgent to exploit the flexibility as much as possible from the power system to suppress the uncertainty introduced by the renewable energy *** research studies the reserve optimization problem considering the Optimal Transmission Switching（OTS）.OTS incorporates the control of transmission assets into the schedule problem to co-optimize the network topology and the units output power *** research has shown that transmission sw:itching is a meaningful measure to explore the flexibility and reduce the operation ***,only a few research focus on using OTS to improve reserve deployment and increase the utilization of wind power under *** this study,two different stochastic models are proposed to optimize the Spinning Reserve（SR）requirement based on Unit Commitment（UC）model with OTS.a)The OTS actions are incorporated in the UC with a probabilistic SR criterion,and the optimal SR amount is determined by minimizing the total cost where the cost related to the expected load not served（ELNS）is penalized in the objective function.b)A UC problem considering wind uncertainty is combined with OTS to facilitate the available wind power *** amount of SR is calculated according to the largest deviation between the post and pre-contingency generation *** dissertation also analyzes the computational complexity of proposed models and presents new heuristic measures to improve the computation *** heuristic measure recommends a transmission line categorization module for choosing the best switchable lines according to the impact on the total costs associated with switching off a particular line,and another heuristic is used to find the optimal value of the maximum number of switchable lines in each optimization *** case studies i

关键词： optimal transmission switching spinning reserve switchable lines unit commitment wind energy

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Saturated anisotropic hydraulic conductivity of a compacted lateritic soil

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第5期10卷 986-991页

作者： roberto Aguiar dos Santos Edmundo Rogerio Esquivel Varzea Grande Institute of Engineering Federal University of Mato Grosso Cuiaba Mato Grosso Brazil Sao Carlos School of Engineering University of Sao Paulo Sao Carlos Sao Paulo Brazil

This study focuses on the saturated anisotropic hydraulic conductivity of a compacted lateritic clayey sandy soil. The effects of the molding water content and the confining stress on the anisotropic hydraulic conductivity are investigated. The hydraulic conductivity is measured with a flexible-wall permeameter. Samples are dynamically compacted into the three compaction states of a standard Proctor compaction curve： the dry branch, optimum water content and wet branch. Depending on the molding water content and confining stress, the hydraulic conductivity may increase or decrease. In addition, the results indicate that, when the samples are compacted to the optimum water content, lower hydraulic conductivity is obtained, except at a confining stress equal to 50 kPa. The increase of the confining stress decreases the hydraulic conductivity for each of the evaluated compaction states. In the wet branch, horizontal hy- draulic conductivity is about 8 times higher than the vertical value. The anisotropic hydraulic conduc- tivities of the dry and wet branches decrease when the confining stress increases, and the opposite is observed in the optimum water content state.

关键词： Hydraulic conductivity Anisotropic behavior Lateritic soil Tropical soil Compacted soil

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Biliary stone causing afferent loop syndrome and pancreatitis

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World Journal of Gastroenterology 2006年第38期12卷 6229-6231页

作者： André Roncon Dias roberto Iglesias Lopes Department of General Surgery Hospital das Clínicas Faculdade de Medicina da Universidade de So Paulo So Paulo Brazil

We report the case of an 84-year-old female who had a partial gastrectomy with Billroth-Ⅱ anastomosis 24 years ago for a benign peptic ulcer who now presented an acute pancreatitis secondary to an afferent loop syndrome. The syndrome was caused by a gallstone that migrated through a cholecystoenteric fistula. This is the first description in the literature of a biliary stone causing afferent loop syndrome.

关键词： Afferent loop syndrome Biliary stone Acute pancreatitis Gallstone ileus

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The "meso" of the rectum and the "meso" of the pancreas: similar terms but distinct concepts in surgical oncology

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Hepatobiliary & Pancreatic Diseases International 2015年第5期14卷 548-551页

作者： Nadia Peparini roberto Caronna Piero Chirletti Azienda Sanitaria Locale Roma H-Distretto 3 Department of Surgical Sciences Sapienza University of Rome

A correspondence between the ＂meso＂ of the rectum and of the pancreas has recently been reported. Here we highlight the differences between mesorectum and mesopancreas. Based on anatomical findings from a series of 89 consecutive pancreaticoduodenectomies and 71 consecutive total mesorectal excisions, we observed that in contrast to the mesorectum, the mesopancreas did not have well-defined anatomic boundaries and was continuous and connected through its components with the para-aortic area. In rectal cancer,tumor deposits and nodal involvement could be confined to the mesorectum（i.e., within the mesorectal fascia）, whereas in pancreatic carcinoma, tumor deposits and nodal metastases occurred in the boundless mesopancreatic area. Total mesorectal excision was made en bloc with the rectum by dissecting along the mesorectal fascia; this was not the case for mesopancreatic excision since anatomical demarcation of the mesopancreas did not exist. Moreover, the growth pattern of pancreatic cancer showed greater dispersion, which was more prominent at the invasive front of the tumor and could potentially affect the status of the resection margin. These findings indicate that the mesorectum and mesopancreas are completely distinct from the pathological, surgical, and oncological standpoints.

关键词： pancreatic head carcinoma surgical procedure therapy pancreatic cancer

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Functional proteomics of adenosine triphosphatase system in the rat striatum during aging

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Neural Regeneration Research 2012年第1期7卷 6-12页

作者： roberto Federico Villa Federica Ferrari Antonella Gorini Department of Forensic Medicine and Pharmacological-Toxicological Sciences Division of Pharmacological and Toxicological Sciences Laboratory of Pharmacology and Molecular Medicine of Central Nervous System University of Pavia

The maximum rates of adenosine triphosphatase （ATPase） systems related to energy consumption were systematically evaluated in synaptic plasma membranes isolated from the striata of male Wistar rats aged 2, 6, 12, 18, and 24 months, because of their key role in presynaptic nerve ending homeostasis. The following enzyme activities were evaluated： sodium-potassium-magnesium adenosine triphosphatase （Na^＋, K^＋, Mg^2＋-ATPase）; ouabain-insensitive magnesium adenosine triphosphatase （Mg^2＋-ATPase）; sodium-potassium adenosine triphosphatase （Na^＋, K^＋-ATPase）; direct magnesium adenosine triphosphatase （Mg^2＋-ATPase）; calcium-magnesium adenosine triphosphatase （Ca^2＋, Mg^2＋-ATPase）; and acetylcholinesterase. The results showed that Na~, K＋-ATPase decreased at 18 and 24 months, Ca^2＋, Mg^2＋-ATPase and acetylcholinesterase decreased from 6 months, while Mg^2＋-ATPase was unmodified. Therefore, ATPases vary independently during aging, suggesting that the ATPase enzyme systems are of neuropathological and pharmacological importance. This could be considered as an experimental model to study regeneration processes, because of the age-dependent modifications of specific synaptic plasma membranes. ATPases cause selective changes in some cerebral functions, especially bioenergetic systems. This could be of physiopathological significance, particularly in many central nervous system diseases, where, during regenerative processes, energy availability is essential.

关键词： ATPase synaptic plasma membranes aging striatum functional proteomics

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Capsule endoscopy in neoplastic diseases

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World Journal of Gastroenterology 2008年第34期14卷 5245-5253页

作者： Marco Pennazio Emanuele Rondonotti roberto de Franchis Division of Gastroenterology 2 Department of Gastroenterology and Clinical Nutrition S. Giovanni A.S. Hospital University of Milan IRCCS Policlinico MangiagalliRegina Elena Foundation Gastroenterology and Gastrointestinal Endoscopy Unit University of Milan IRCCS Policlinico MangiagalliRegina Elena Foundation Gastroenterology and Gastrointestinal Endoscopy Unit

Until recently, diagnosis and management of small-bowel tumors were delayed by the diffi culty of access to the small bowel and the poor diagnostic capabilities of the available diagnostic techniques. An array of new methods has recently been developed, increasing the possibility of detecting these tumors at an earlier stage. Capsule endoscopy (CE) appears to be an ideal tool to recognize the presence of neoplastic lesions along this organ, since it is non-invasive and enables the entire small bowel to be visualized. High- quality images of the small-bowel mucosa may be captured and small and ? at lesions recognized, without exposure to radiation. Recent studies on a large population of patients undergoing CE have reported small-bowel tumor frequency only slightly above that reported in previous surgical series (range, 1.6%-2.4%) and have also confirmed that the main clinical indication to CE in patients with small-bowel tumors is obscure gastrointestinal (GI) bleeding. The majority of tumors identified by CE are malignant; many were unsuspected and not found by other methods. However, it remains difficult to identify pathology and tumor type based on the lesion’s endoscopic appearance. Despite its limitations, CE provides crucial information leading in most cases to changes in subsequent patient management. Whether the use of CE in combination with other new diagnostic (MRI or multidetector CT enterography) and therapeutic (Push- and-pull enteroscopy) techniques will lead to earlier diagnosis and treatment of these neoplasms, ultimately resulting in a survival advantage and in cost savings,remains to be determined through carefully-designed studies.

关键词： Capsule endoscopy Enteroscopy Obscure gastrointestinal bleeding Small-bowel tumors Polyposis syndromes

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Tokenomics and blockchain tokens: A design-oriented morphological framework

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Blockchain(Research and Applications) 2022年第1期3卷 80-95页

作者： Pierluigi Freni Enrico Ferro roberto Moncada Business Model Innovation LINKS FoundationTurin10138Italy

Blockchain technology has been around for more than ten years,nevertheless,the knowledge about its economic and business implications is still fragmented and *** present article intends to tackle this issue with a twofold *** first is an analysis of the shift from economics to tokenomics highlighting the central role played by tokens within blockchain-based *** second is a framework for tokens design leveraging a morphological analysis deeply grounded in the *** blockchain becomes a mainstream phenomenon,the value of the work proposed lies in lowering the cognitive barriers and in clarifying the space of available options for private and public actors willing to leverage tokenization in their daily operations.

关键词： Blockchain Tokenization Tokenomics Classification framework Token design

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‘Smart’copycat mutual funds:on the performance of partial imitation strategies

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Financial Innovation 2022年第1期8卷 2508-2538页

作者： roberto Stein Department of Finance University of Nebraska-Lincoln730 N 14th StLincolnNE 68588USA

Using a novel measure of stock-level trade imitation,we uncover‘smart’copycats:fund managers that use their own information when beneficial,and otherwise imitate other managers’better *** to previous research,we find that these partial imitation strategies lead to ***‘Copycat Score’combines the propensity to imitate and to lead *** at the high and low ends of the score outperform all *** Copycat Score is persistent in time,related to other measures of skill,and a good predictor of fund *** conclude that smart copycatting is another skill of successful fund managers.

关键词： Copycat portfolios Mutual funds Portfolio holdings Fund performance Fund manager skill

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Proximal Methods with Bregman Distances to Solve VIP on Hadamard Manifolds with Null Sectional Curvature

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Journal of the Operations Research Society of China 2021年第3期9卷 499-523页

作者： Erik Alex Papa Quiroz Paulo roberto Oliveira Universidad Nacional Mayor de San Marcos Universidad Privada del NorteLimaPeru PESC-COPPE Federal University of Rio de JaneiroRio de Janeiro CEP 21941-972Brazil

We present an extension of the proximal point method with Bregman distances to solve variational inequality problems(VIP)on Hadamard manifolds with null sectional *** some natural assumptions,as for example,the existence of solutions of the VIP and the monotonicity of the multivalued vector field,we prove that the sequence of the iterates given by the method converges to a solution of the ***,this convergence is linear or superlinear with respect to the Bregman distance.

关键词： Proximal point methods Hadamard manifolds Bregman distances Variational inequality problems Monotone vector field

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Hyperglycemia in acute ischemic stroke: physiopathological and therapeutic complexity

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Neural Regeneration Research 2022年第2期17卷 292-299页

作者： Federica Ferrari Antonio Moretti roberto Federico Villa Department of Biology and Biotechnology Laboratory of Pharmacology and Molecular Medicine of Central Nervous SystemUniversity of PaviaVia FerrataPaviaItaly

Diabetes mellitus and associated chronic hyperglycemia enhance the risk of acute ischemic stroke and lead to worsened clinical outcome and increased mortality. However, post-stroke hyperglycemia is also present in a number of non-diabetic patients after acute ischemic stroke, presumably as a stress response. The aim of this review is to summarize the main effects of hyperglycemia when associated to ischemic injury in acute stroke patients, highlighting the clinical and neurological outcomes in these conditions and after the administration of the currently approved pharmacological treatment, i.e. insulin. The disappointing results of the clinical trials on insulin(including the hypoglycemic events) demand a change of strategy based on more focused therapies. Starting from the comprehensive evaluation of the physiopathological alterations occurring in the ischemic brain during hyperglycemic conditions, the effects of various classes of glucose-lowering drugs are reviewed, such as glucose-like peptide-1 receptor agonists, DPP-4 inhibitors and sodium glucose cotransporter 2 inhibitors, in the perspective of overcoming the up-to-date limitations and of evaluating the effectiveness of new potential therapeutic strategies.

关键词： acute ischemic stroke diabetes mellitus DPP-4 inhibitor glucose-like peptide-1 receptor agonist hyperglycemia hypoglycemia insulin physiopathology sodium glucose cotransporter 2 inhibitor

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