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供体母羊及与配公羊个体对波尔山羊胚胎移植效率的影响

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西南农业学报 2003年第3期16卷 76-78页

作者：李红马保华邓小东张红曹冶周洪群李键四川省动物生物技术研究中心四川成都610066 西北农林科技大学动物科技学院陕西杨凌712100

对135只波尔山羊供体母羊进行超排处理,回收卵总数2504枚,平均18 55±7 63枚,其中可用胚2182枚,平均16 16±7 46枚。将2127枚鲜胚移植给1182只受体,妊娠率为63 03%(745/1182),移植胚胎成羔率为52 1%(1108/2127)。试验结果表明,供体各个... 详细信息

对135只波尔山羊供体母羊进行超排处理,回收卵总数2504枚,平均18 55±7 63枚,其中可用胚2182枚,平均16 16±7 46枚。将2127枚鲜胚移植给1182只受体,妊娠率为63 03%(745/1182),移植胚胎成羔率为52 1%(1108/2127)。试验结果表明,供体各个体之间所获得的胚胎移植成羔率存在着显著差异(P<0 05),胚胎成羔率大于80%的供体平均每只获胚胎移植羔羊14 8±4 27只,胚胎成羔率小于20%的供体平均每只获胚胎移植羔羊1 83±1 17只,其中个体获得羔羊最多的为21只(21/26)。有9 63%的供体胚胎移植成羔率大于80%,有4 44%的供体胚胎移植成羔率小于20%。14只公羊配种的135只供体获得的胚胎可用率同样存在着显著差异(P<0 05)。

关键词：波尔山羊胚胎移植超数排卵供体受体胚胎成羔率

Nutritional Assessment of Gynecological cancer Patients in china

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Journal of Nutritional Oncology 2017年第3期2卷 145-152页

作者： wen Ying Li Guo Lan Gao chun Hua Song chang wang Zeng Qing Guo Yuan Lin Ying Ying Shi wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua wang Jing wu Ying He Jia Jun Yang Fu Xiang Zhou cong Hua Xie Xin Xia Song Gong Yan chen wen Jun Ma Su Xia Luo Zi Hua chen Ming Hua cong Jian Xiong wu chun Ling Zhou wei wang Qi Luo ong Mei Shi Yu Mei Qi Hai Ping Jiang wen Xian Guan Jun Qiang chen Jia Xin chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun wen Ou Qing chuan Zhao Zhen Ming Fu Hong Xia Xu wei Li Han Ping Shi Investigation on nutrition status and its clinical outcome of common cancers (INScOc) group Department of Obstetrics and Gynecology Aviation General HospitalChaoyang DistrictBeijingChina Department of Nutrition and Metabolism of Oncology Affiliated Provincial Hospital of Anhui Medical UniversityHefeiAnhui 230031China Department of clinical Nutrition the First Hospital of Hefei Medical UniversityShijiazhuangHebei 050031China Department of Gastrointestinal Surgery Institute of Gastroenterologythe First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650032China Department of clinical Nutrition the First People’s Hospital of KashiXinjiang 844000China Zhongshan chenxinghai Hospital(Affiliated Zhongshanchenxinghai Hospital of Guangdong Medical University) ZhongshanGuangdong 528400China Department of clinical Nutrition Chongqing General HospitalChongqing 40014China Department of colorectal and Anal Surgery Huizhou Municipal Central HospitalHuizhouGuangdong 516001China Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhanHubei 430071China Department of Oncology Xingtai People’s HospitalHebei Medical UniversityXingtaiHebei 054031China The First Department of Tumor Hospital of Harbin Medical University HarbinHeilongjiang 150085China college of Medicine Chinese Academy of SciencesHuairou DistrictBeijingChina Department of Nutrition Guangdong General HospitalGuangdong Academy of Medical SciencesGuangzhouGuangdong 510080China Department of Oncology Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer HospitalZhengzhouHenan 450008China Department of General Surgery Xiangya HospitalCentral South UniversityChangshaHunan 410008China comprehensive Oncology Department Cancer HospitalChinese Academy of Medical SciencesBeijing 100021China Abdominal Surgery Department Cancer Institute and HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100021China The Fourth Affiliated Hospital Harbin Medical UniversityHarbinHeilongjiang 150001China cancer center the First People’s Hospital of

Background Malnutrition is common among cancer patients,but few studies have evaluated the nutritional status among gynecological cancer patients in *** study aimed to assess the nutritional status of women with gynecological cancer using the patient-generated subjective global assessment(PG-SGA).Methods Data for gynecological cancer patients treated at 44 tertiary hospitals were retrieved from a multicenter study on tumor *** R Software was used for statistical *** analyses of PG-SGA scores were performed using the chi-squared test for categorical variables and the wilcoxon-rank sum test or Kruskal-wallis test for continuous variables,as *** significance level was *** Data for 1962 women with three types of gynecological cancer(cervical,uterine and ovarian cancer)were used for the data *** median PG-SGA score was 4(interquartile range,IQR:1,8),the median participants’age was 51(IQR:46,59)years old,and the patients had a median BMI of 22.9(IQR:20.7,25.4).The percentages of women who had a medical co-morbidity,or had undergone any radical resection,chemotherapy,or radiotherapy were approximately 27.7%,55.4%,52.5%,and 30.2%,*** levels of serum albumin and high density lipoprotein cholesterol(HDL-c)were 40.1g/L(IQR:36.8,43.1)and 1.2mmol/L(IQR:1.0,1.5),*** identified risk factors for malnutrition based on the PG-SGA score were age(0.05±0.01,p=0.002),BMI(-0.34±0.04,pcal co-morbidity(0.95±0.33,p=0.004),receiving radiotherapy(1.52±0.31,pc(-1.12±0.35,p=0.001)as indicated by a linear regression *** A higher PG-SGA score is positively associated with the age of the patient,having a medical co-morbidity,and receiving radiotherapy,and is negatively related to the patients’BMI and serum albumin and HDL-c levels.

关键词： Albumin Gynecological cancer HDL-c Malnutrition Patient-generated Subjective Global Assessment

精氨酸限制饮食减缓视网膜及脉络膜脑回样萎缩患者的视力丧失

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世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 20-21页

作者： Kaiser-Kupfer M.I. caruso R.c. Valle D. Reed G.F. 邢咏新 6016 Neilwood Dr Rockville MD 20852 United States Dr.

Objectives: To quantify the effect of long-term reduction of plasma ornithine levels through adherence to an arginine-restricted diet on visual function in patients of all ages with gyrate atrophy of the retina and choroid. Methods: A l ong-term observational study was conducted on 27 patients with gyrate atrophy, 17 of whom elected to comply with the arginine-restricted diet and 10 who were unable to comply. The mean rates of change in the electroretinogram combined res ponse, electroretinogram flicker response, and kinetic and static perimetry were determined. Results: After mean follow-up of 13.9 years for the patients on th e diet and 14.1 years for those not on the diet, the mean rates of change for th e diet group compared with those of the no-diet group were statistically signif icantly slower for all outcome measures (age-adjusted Pcept for stati c perimetry (P=.06). conclusions: Adhering to an arginine-restricted diet so as to lower the plasma ornithine level below an average of 5.29 to 6.61 mg/dL (400 -500 μmol/L) will slow the loss of function as measured by sequential electror etinography and visual field examinations.

关键词：限制饮食脑回视力丧失精氨酸视功能闪光视网膜电图鸟氨酸平均变化率血浆水平观察性研究

南通市如皋县宫颈浸润性鳞癌的地区差异及其与HPV16、HPV18感染的关系

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苏州大学学报（医学版） 2003年第6期23卷 781-782,788页

作者：杨其昌冯一中韩枋朱惠君季晓华苏州大学医学院病理学教研室江苏苏州215007 南通医学院第二附属医院病理科江苏南通226001

目的　探讨人乳头状瘤病毒 16和 18型 (HPV16、HPV18)感染状况与宫颈癌的地区分布间的相关性。方法　应用免疫组化技术 ,对如皋县东北部 (宫颈癌高发区 )的宫颈浸润性鳞癌 3 9例和西南部 (低发区 )的宫颈浸润性鳞癌 3 8例分别进行HPV16... 详细信息

目的　探讨人乳头状瘤病毒 16和 18型 (HPV16、HPV18)感染状况与宫颈癌的地区分布间的相关性。方法　应用免疫组化技术 ,对如皋县东北部 (宫颈癌高发区 )的宫颈浸润性鳞癌 3 9例和西南部 (低发区 )的宫颈浸润性鳞癌 3 8例分别进行HPV16和HPV18检测。结果　HPV16在高发区和低发区的阳性率分别为 64.1%和71.0 5% (P >0 .0 5) ,HPV18在高发区和低发区的阳性率分别为 3 8.46%和 42 .1% (P >0 .0 5)。另外本资料显示高发区患者年龄 (平均 54.2岁 )较低发区 (平均 61岁 )小 (P <0 .0 5)。结论　HPV16和HPV18作为宫颈鳞癌的病原学因子 ,其在不同地区间可能是相似的。本研究中高。

关键词：宫颈癌人乳头状瘤病毒如皋县

charge-changing cross section measurements of 300 MeV/nucleon^(28)Si on carbon and data analysis

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中国物理c:英文版 2023年第8期47卷 13-21页

作者：王长建郭戈王惠仁宋雨楠孙保华谷畑勇夫寺嶋知魏秀琳徐俊瑶徐晓栋张寂潮郑勇竺礼华曹勇樊广伟高丙水韩加星李光帅鲁辰桂齐浩天秦赟孙志宇万鲁平王凯龙王世陶王昕旭张湄雪张文文张小彬章学恒周子铖 School of Physics Beihang UniversityBeijing 100191China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China School of chemical Engineering Anhui University of Science and TechnologyHuainan 232001China

charge-changing cross section(σcc)measurements via the transmission method have recently seen significant progress with the aim of determining the charge radii of exotic *** this work,we report a newσcc measurement of 304(9)MeV/nucleon^(28)Si on carbon at the second Radioactive Ion Beam Line in Lanzhou(RIBLL2)and describe the data analysis procedure in *** procedure is essential for evaluating the systematic uncertainty in the transmission *** determinedσcc of 1125(11)mb is found to be consistent with the existing data at similar *** present work will serve as a reference forσcc determinations at RIBLL2.

关键词： projectile fragmentation transmission method charge-changing cross section particle identi-fication

大肠癌肝转移患者血清中相关癌基因甲基化水平的检测

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中国临床医学 2016年第6期23卷 798-800页

作者：齐翀郝总洪亮殷庆章复旦大学附属上海市第五人民医院普通外科，上海 200240

目的:探讨大肠癌肝转移患者血清相关癌基因甲基化水平的变化。方法:选择2011年9月—2013年12月因原发性大肠癌入院伴或不伴肝转移患者各32例,分别作为试验组A和试验组B。所有患者在入院之前均未进行化疗或放疗。另选择20例健康体检者作... 详细信息

目的:探讨大肠癌肝转移患者血清相关癌基因甲基化水平的变化。方法:选择2011年9月—2013年12月因原发性大肠癌入院伴或不伴肝转移患者各32例,分别作为试验组A和试验组B。所有患者在入院之前均未进行化疗或放疗。另选择20例健康体检者作为对照组。提取研究对象血清中DNA,采用甲基化特异性PcR法检测E-cad、ID4、ESR1、APc或HAcE基因甲基化异常。结果:试验组A检测出19例E-cad、ID4、ESR1、APc或HAcE甲基化异常;试验组B检测出10例Ecad、ID4、ESR1、APc或HAcE甲基化异常;对照组未检测出E-cad、ID4、ESR1、APc或HAcE甲基化异常。3组间差异有统计学意义(Pcad、ID4、ESR1、APc和HAcE基因甲基化状态联合检测有利于大肠癌肝转移的临床诊治。

关键词：大肠癌肝转移甲基化癌基因

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复发性卒中与大麻的使用有关

世界核心医学期刊文摘（神经病学分册） 2005年第7期1卷 30-30页

作者： Mateo I. Pinedo A. Gomez-Beldarrain M. J.c.Garcia-Monco 赵睿 Service of Neurology Hospital de Galdacano48960 Galdacano Vizcaya Spain Dr.

Drug misuse represents a risk factor for cerebrovascular disease,especially am ong young people. Despite the fact that cannabisis the most widely used illicit drug, there are only a few reports associating its use with cerebrovascular dise ase. we describe a patient who suffered three ischaemic strokes immediately afte r cannabis consumption. Other stroke aetiologies were ruled out, and neuro imagi ng revealed infarcts in different arterial areas as well as evidence of non-ath erosclerotic arterial disease,which suggests an underlying vasculopathy of uncer tain (toxicor inflammatory) origin. cannabis use may be associated with ischaemi c stroke in young patients,but its mechanismis unclear.

关键词：复发性卒中缺血性卒中脑血管病影像学检查 unclear 违禁药物 suffered 发病机制 young immediately

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中国2型糖尿病患者餐后高血糖管理专家共识

药品评价 2016年第7期13卷 5-12页

作者：母义明纪立农杨文英洪天配朱大龙单忠艳郭立新陈璐璐童南伟李焱李延兵李启富彭永德肖新华姬秋和余学锋石勇铨孙子林李益明李强冉兴无李全民尹士男吕肖锋祝开思解放军总医院内分泌科北京100853 北京大学人民医院内分泌科北京100044 中日友好医院内分泌代谢中心北京100029 北京大学第三医院内分泌科北京100191 南京鼓楼医院内分泌科江苏南京210000 中国医科大学第一附属医院内分泌科辽宁沈阳110001 卫生部北京医院内分泌科北京100730 华中科技大学同济医学院附属协和医院内分泌科湖北武汉430030 四川大学华西医院内分泌代谢科四川成都610041 中山大学孙逸仙纪念医院内分泌科广东广州510120 中山大学附属第一医院内分泌科广东广州510000 重庆医科大学附属第一医院内分泌科重庆400016 上海交通大学附属第一人民医院内分泌科上海200080 北京协和医院内分泌科北京100730 第四军医大学西京医院内分泌科陕西西安710032 华中科技大学同济医学院附属同济医院内分泌科湖北武汉430030 第二军医大学附属长征医院内分泌科上海200433 东南大学附属中大医院内分泌科江苏南京210009 复旦大学附属华山医院内分泌科上海200433 哈尔滨医科大学附属第二医院内分泌科黑龙江哈尔滨150081 火箭军总医院内分泌科北京100088 解放军总医院附属第一医院内分泌科北京100048 北京陆军总医院内分泌科北京100700 解放军第305医院内分泌科北京100017

中国2型糖尿病伴餐后血糖(postprandial plasma glucose,PPG)升高的患者比例高。控制餐后高血糖对于Hb A1c达标非常重要。为了帮助临床医生更好地管理糖尿病,中国专家基于国内外临床证据及临床经验,制订了《中国2型糖尿病患者餐后高血... 详细信息

中国2型糖尿病伴餐后血糖(postprandial plasma glucose,PPG)升高的患者比例高。控制餐后高血糖对于Hb A1c达标非常重要。为了帮助临床医生更好地管理糖尿病,中国专家基于国内外临床证据及临床经验,制订了《中国2型糖尿病患者餐后高血糖管理专家共识》。本共识概述了餐后高血糖的定义和危害,餐后高血糖与糖尿病微血管、大血管并发症发生风险之间的关系,餐后高血糖的管理策略,以及控制餐后高血糖的临床意义。

关键词：餐后高血糖糖尿病并发症共识