检索结果-南通市图书馆

Macrometastasis at selective lymph node biopsy:A practical goingfor-the-one clinical scoring system to personalize decision making

引用

World Journal of Clinical oncology 2021年第8期12卷 675-687页

作者： Mercedes Herrero Raquel Ciérvide Maria Elisa Calle-Purón Javier valero Paula Buelga Isabel Rodriguez-Bertos Leticia Benassi Angel Montero Department of Gynecology and obstetrics HM HospitalesMadrid 28050Spain Department of Radiation oncology HM HospitalesMadrid 28050Spain Department of Preventive Medicine and Public Health Complutense University of MadridMadrid 28050Spain

BACKGRoUND Axillary sentinel lymph node biopsy(SLNB)is standard treatment for patients with clinically and pathological negative lymph ***,the role of completion axillary lymph node dissection(cALND)following positive sentinel lymph node biopsy(SLNB)is *** To identify a subgroup of women with high axillary tumor burden undergoing SLNB in whom cALND can be safely omitted in order to reduce the risk of longterm complications and create a Preoperative Clinical Risk Index(PCRI)that helps us in our clinical practice to optimize the selection of these *** Patients with positive SLNB who underwent a cALND were included in this *** and multivariate analysis of prognostic and predictive factors were used to create a PCRI for safely omitting *** From May 2007 to April 2014,we performed 1140 SLN biopsies,of which 125 were positive for tumor and justified to practice a posterior *** findings at SLNB were micrometastases(mic)in 29 cases(23.4%)and macrometastasis(MAC)in 95 cases(76.6%).on univariate analysis of the 95 patients with MAC,statistically significant factors included:age,grade,phenotype,histology,lymphovascular invasion,lymph-node tumor size,and number of positive *** multivariate analysis,only lymph-node tumor size(≤20 mm)and number of positive SLN(>1)retained significance.A numerical tool was created giving each of the parameters a value to predict preoperatively which patients would not benefit from *** with a PCRI≤15 has low probability(of having additional lymph node involvement,a PRCI between 15-17.6 has a probability of 43%,and the probability increases to 69%in patients with a PCRI>*** The PCRI seems to be a useful tool to prospectively estimate the risk of nodal involvement after positive SLN and to identify those patients who could omit *** prospective studies are necessary to validate PCRI clinical generalization.

关键词： Sentinel lymph node biopsy Complete axillary lymph node dissection Preoperative clinical risk index Macrometastasis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Isolation,Identification and Germplasm Preservation of Different Native Spirulina Species from Western Mexico

引用

American Journal of Plant Sciences 2013年第12期4卷 65-71页

作者： Rout Nutan Prasad Khandual Sanghamitra Gutierrez-Mora Antonia Gallardo-Valdéz Juan Rodriguez-Garay Benjamin Ibarra-Montoya JLuis Vega-valero Guillermo Centro de Investigación y Asistencia en Tecnología y Diseno del Estado de Jalisco A.C.Av.Normalistas#800Colinas de la NormalGuadalajaraJaliscoMexico Biotecnología Mexicana de Microalgas S.A.de C.V.Sta.Maria 136 Conlonia TepeyacZapopanJaliscoMexico

Spirulina is an edible algae and has a wide range of pharmaceutical applications in addition to its nutritional value. Isolation and identification of several Spirulina species were conducted in the western part of Mexico especially in the state of Jalisco. The purification strategy consisted of five optimized processing steps: 1) washing and centrifugation, 2) chemical treatment, 3) micromanipulation, 4) serial dilution, and 5) plating. Four species were isolated from different locations and two out of these four species were identified taxonomically up to the species level: Spirulina subsalsa and S. major. For short term conservation (30 days), the strains were maintained in liquid and solid agar medium at 10?C and 4?C. For medium term (few months), they were preserved in solid medium under a dried condition as agar flakes and for long term, cryopreservation was employed by using 5% and 10% DMSo, glycerol and methanol as osmoprotectants in liquid nitrogen. For short term preservation nearly 90% liquid and 100% agar recovered strains were viable after one month at both temperatures. In the case of the agar flakes, cells were viable after three months of conservation at room temperature. Cryopreservation did not give any suitable results after three months of conservation. Variable and two-step improved cryopreservation processes are now in progress for conservation.

关键词： Germplasm Cryopreservation Spirulina Long Term Preservation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cost-effectiveness of endoscopic ultrasound-guided coils plus cyanoacrylate injection compared to endoscopic cyanoacrylate injection in the management of gastric varices

引用

World Journal of Gastrointestinal Endoscopy 2021年第1期13卷 13-23页

作者： Carlos Robles-Medranda Joao Autran Nebel Miguel Puga-Tejada Roberto oleas Jorge Baquerizo-Burgos Jesenia ospina-Arboleda Manuel valero Hannah Pitanga-Lukashok Gastroenterology and Endoscopy Division Instituto Ecuatoriano de Enfermedades DigestivasGuayaquil 090505GuayasEcuador

BACKGRoUND Cyanoacrylate(CYA)injection can be performed using a standard upper endoscopy technique or under endoscopic ultrasound(EUS)guidance alone or in combination with *** is little information available on the economic impact of these treatment *** To compare the cost-effectiveness of treating gastric varices by CYA injection via upper endoscopy vs coils plus CYA guided by *** This was an observational,descriptive,and retrospective *** were allocated into two groups:A CYA group and coils plus CYA *** baseline characteristics were compared,and a cost analysis was *** overall,36 patients were included(19 in the CYA group and 17 in the coils+CYA group).All patients in the CYA group had acute *** underwent a higher mean number of procedures(1.47 vs 1,P=0.025),and the mean volume of glue used was 2.15 vs 1.65 mL,P=*** coils+CYA group showed a higher technical success rate(100%vs 84.2%),with a complication rate similar to the CYA *** majority of CYA patients required hospitalization,and although the mean total per procedure cost was lower(United States$1350.29 vs United States$2978),the mean total treatment cost was significantly different(United States$11060.89 for CYA vs United States$3007.13 for coils+CYA,P=0.03).CoNCLUSIoN The use of EUS-guided coils plus cyanoacrylate is more cost-effective than cyanoacrylate injection when the total costs are ***,randomized trials are needed to validate the cost-effectiveness of the EUS-guided approach to treat gastric varices.

关键词： Cost-effectiveness Endoscopic ultrasound-guided therapy Gastric varices Gastrointestinal bleeding Hemostasis Therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Clinical impact of confocal laser endomicroscopy in the management of gastrointestinal lesions with an uncertain diagnosis

引用

World Journal of Gastrointestinal Endoscopy 2017年第8期9卷 389-395页

作者： Carlos Robles-Medranda Maria Vargas Jesenia ospina Miguel Puga-Tejada Manuel valero Miguel Soria Gladys Bravo Carlos Robles-Jara Hannah Pitanga Lukashok Gastroenterology and Endoscopy Division Instituto Ecuatoriano de Enfermedades DigestivasUniversity Hospital OMNIGuayaquil 090505Ecuador

To evaluate the clinical impact of confocal laser endomicroscopy (CLE) in the diagnosis and management of patients with an uncertain diagnosis. METHoDSA retrospective chart review was performed. Patients who underwent CLE between November 2013 and october 2015 and exhibited a poor correlation between endoscopic and histological findings were included. Baseline characteristics, indications, previous diagnostic studies, findings at the time of CLE, clinical management and histological results were analyzed. Interventions based on CLE findings were also analyzed. We compared the diagnostic accuracy of CLE and target biopsies of surgical specimens. RESULTSA total of 144 patients were included. of these, 51% (74/144) were female. The mean age was 51 years old. In all, 41/144 (28.4%) lesions were neoplastic (13 bile duct, 10 gastric, 8 esophageal, 6 colonic, 1 duodenal, 1 rectal, 1 ampulloma and 1 pancreatic). The sensitivity, specificity, positive predictive value, negative predictive value, and observed agreement when CLE was used to detect N-lesions were 85.37%, 87.38%, 72.92%, 93.75% and 86.81%, respectively. Cohen’s Kappa was 69.20%, thus indicating good agreement. Changes in management were observed in 54% of the cases. CoNCLUSIoNCLE is a new diagnostic tool that has a significant clinical impact on the diagnosis and treatment of patients with uncertain diagnosis.

关键词： Confocal laser endomicroscopy In vivo microscopy Barret esophagus Gastrointestinal cancer Pancreatic cyst Biliary strictures

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Application of 3A Zeolite Prepared from Venezuelan Kaolin for Removal of Pb (II) from Wastewater and Its Determination by Flame Atomic Absorption Spectrometry

引用

American Journal of Analytical Chemistry 2013年第10期4卷 584-593页

作者： Wendy Rondón David Freire Zully de Benzo Angela B. Sifontes Yorbin González Maribel valero Joaquín L. Brito Laboratorio de Espectroscopia Molecular Facultad de Ciencias Universidad de Los Andes Mérida Venezuela Laboratorio de Fisicoquímica de Superficies Centro de Química Instituto Venezolano de Investigaciones Científicas IVIC Caracas Venezuela Laboratorio de Química Analítica Centro de Química Instituto Venezolano de Investigaciones Científicas IVIC Caracas Venezuela

This work consists in the use of a 3A zeolite (K-LTA) obtained by a process of exchange of sodium for potassium (4A zeolite), synthesized from Venezuelan kaolin for the removal of Pb (II) ions from aqueous solutions by batch process mode in order to consider its application in treating industrial wastewaters. The 3A zeolite was characterized for X-ray powder diffraction (XRD), Fourier Transform infrared spectroscopy (FTIR) and scanning electron microscopy and energy dispersive X-ray microanalysis (SEM-EDX). The metal concentration in the equilibrium Ce (mg·L-1) after adsorption with 3A zeolite was analyzed using flame atomic absorption spectrometry (FAAS). The influences of the solution pH, contact time, metal initial concentration and adsorbent dosage have been studied. The retention of metal occurring at pH values around 6.5 and the adsorption equilibrium was obtained at 60 min. The equilibrium process was well described by Langmuir, Freundlich and Dubinin-Radushkevich (D-R) isotherm models. The Langmuir parameters qm (mg·g-1) and b (L·mg-1) (which are related to the sorption capacity and constant of sorption energy) obtained were 14.64 and 5.42 respectively. The Pb (II) experimental uptake was about 14.56 mg·g-1, a little smaller than the theoretical one given by Langmuir isotherm model. The regression parameters and correlation coefficients (R) indicate that the adsorption data for Pb (II) removal fit better the Langmuir isotherm model. Moreover, 0 1/n 1 (1/n is 0.13), indicating that adsorption of metal ions on the zeolite, is a favorable physical process. The application of removing of the metal lead from real samples was examined by industrial wastewater samples. For all samples, the percentage of recovery was found with accuracy of more than 98%. The present work suggests 3A zeolite used as a sorbent material with relatively low cost, obtained from Venezuelan raw material;it is a candidate for removal lead ion and probably other cationic heavy metal species

关键词： Adsorption Wastewater Lead (II) Ion Zeolite Langmuir Isotherm FAAS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High-definition optical magnification with digital chromoendoscopy detects gastric mucosal changes in dyspeptic-patients

引用

World Journal of Gastrointestinal Endoscopy 2020年第1期12卷 23-32页

作者： Carlos Robles-Medranda Manuel valero Miguel Puga-Tejada Roberto oleas Jorge Baquerizo-Burgos Miguel Soria-Alcívar Haydee Alvarado-Escobar Hannah Pitanga-Lukashok Gastroenterology and Endoscopy Division Instituto Ecuatoriano de Enfermedades Digestivas(IECED)

BACKGRoUND Accurate detection of gastric infection by Helicobacter pylori(***)and premalignant lesions are important for effective provision of treatment,preventing the development of gastric *** enhancement systems with optical magnification improved the identification of mucosal superficial and vascular patterns in patients with *** To evaluate an optical enhancement system with high-definition magnification,for diagnosis of normal gastric mucosa,***-associated gastritis,and gastric *** A cross-sectional,nonrandomized study from November 2015 to April 2016 performed in a single-tertiary academic center from ***-two consecutive patients with functional dyspepsia according to the Rome III criteria,were tested for *** using a stool antigen test and were assigned to an Hp+group or an Hp−control *** with highdefinition optical magnification and digital chromoendoscopy was performed,and patients were classified into 4 groups,in accordance to the microvasculararchitecture pattern of the *** and intraobserver agreement among operators were *** of the 72 participants,35 were Hp+and 37 were Hp−.Among 10 patients with normal mucosal histology in biopsy samples,90%had a Type I pattern of microvascular architecture by *** participants with type IIa and type IIb patterns,significantly more were Hp+than Hp−(32 vs 8),and most(31 out of 40)had histological diagnoses of chronic active *** of the three participants with a histological diagnosis of atrophy had a type III microvascular *** type I pattern predicted normal mucosa,type IIa–IIb predicted *** infection,and type III predicted atrophy with sensitivities of 90.0%,91.4%,and 66.7%,*** intraobserver and interobserver agreements had kappa values of 0.91 and 0.89,*** High-definition optical magnification with digital chromoendoscopy is useful

关键词： Gastritis Helicobacter pylori Gastric mucosa Atrophic Endoscopy Digestive system

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

关于口译在与西班牙监狱中外籍女性囚犯的语言沟通中所起作用的情况分析

引用

湖南涉外经济学院学报 2015年第2期 46-52页

作者： Carmen valero Garcés Esperanza Mojica López 陈藜西班牙阿尔卡拉大学湖南涉外经济学院外国语学院

根据西班牙国家统计局2011年官方数据统计,在全西班牙监狱系统中女性囚犯共有3367名,其中,西语非母语的外籍女囚犯共1921名,占总人数的57%。这些外籍女囚在从被批捕的那一刻起便有权了解有关自己刑事诉讼的相关讯息。但法院方和外籍女... 详细信息

根据西班牙国家统计局2011年官方数据统计,在全西班牙监狱系统中女性囚犯共有3367名,其中,西语非母语的外籍女囚犯共1921名,占总人数的57%。这些外籍女囚在从被批捕的那一刻起便有权了解有关自己刑事诉讼的相关讯息。但法院方和外籍女囚方在语言沟通方面的障碍有可能会导致妨碍执法,或降低执法效率。通过对以往的研究表明,在对外籍囚犯案件的审理中并没有专业口译人员的介入,双方沟通使用的是其它资源和策略。

关键词：口译西语非母语女囚犯语言沟通难题

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Management and outcome of Pregnant Women with HIV Acquired by Vertical Transmission

引用

open Journal of obstetrics and Gynecology 2015年第9期5卷 470-474页

作者： Verónica Serrano de la Cruz Delgado Alicia Martínez Varea María José Nú?ez valero Vicente Diago Almela Vicente Maiques Montesinos Amparo García Tejedor Alfredo Perales Marín HUP La Fe ValenciaSpain

The majority of children with perinatally acquired human immunodeficiency virus (HIV) do not survive beyond childhood but this is changing due to the benefit of antiretroviral therapy for the perinatally infected cohort, so affected children are now approaching the age to be mothers. The aim of this article is to evaluate the outcomes of pregnant women with HIV acquired by vertical transmission in our centre and encourage the results obtained in “Thirty Years Later: Pregnancies in Female Perinatally Infected with Human Immunodeficiency Virus-1”, a review article published in this journal in 2012 [2]. We report 6 patients with eight pregnancies with HIV acquired by vertical transmission. They delivered a total of nine newborns between 2004 and 2013. In any case, mother-to-child transmission was reported. The management of pregnant women with HIV acquired by vertical transmission is complicated, since the patients are the most of the cases young and the compliance to the treatment may be poor. The prematurity was the more frequent complication and the cesarean section was the more frequent form of ending. In our case series, mother-to-child transmission was absent.

关键词： HIV Perinatally Acquired HIV Vertical Transmission HIV Pregnancy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessing radiation dose for postoperative radiotherapy in prostate cancer: Real world data

引用

World Journal of Clinical oncology 2022年第7期13卷 652-662页

作者： Asunción Hervás-Morón Jose Domínguez-Rullán Victor Duque Santana Mireia valero Carmen Vallejo Sonsoles Sancho Juan David García Fuentes Miguel Cámara Gallego Fernando López-Campos Department of Radiation oncology Hospital Universitario Ramón Y CajalMadrid 28034Spain Department of Medical Physics Hospital Universitario Ramón Y CajalMadrid 28034Spain

BACKGRoUND Approximately 30%of patients with localized prostate cancer(PCa)who undergo radical prostatectomy will develop biochemical *** these patients,the only potentially curative treatment is postoperative radiotherapy(PoRT)with or without hormone ***,the optimal radiotherapy dose is unknown due to the limited data *** To determine whether the postoperative radiotherapy dose influences biochemical failure-free survival(BFFS)in patients with *** Retrospective analysis of patients who underwent radical prostatectomy for PCa followed by PoRT-either adjuvant radiotherapy(ART)or salvage radiotherapy(SRT)-between April 2002 and July *** 2002 to 2010,the prescribed radiation dose to the surgical bed was 66-70 Gy in fractions of 2 Gy;from 2010 until July 2015,the prescribed dose was 70-72 *** were grouped into three categories according to the total dose administered:66-68 Gy,70 Gy,and 72 *** primary endpoint was BFFS,defined as the post-radiotherapy prostatespecific antigen(PSA)nadir+0.2 ng/*** endpoints were overall survival(oS),cancer-specific survival(CSS),and metastasis-free survival(MFS;based on conventional imaging tests).Treatment-related genitourinary(GU)and gastrointestinal(GI)toxicity was evaluated according to Radiation Therapy oncology Group/European organization for Research and Treatment of Cancer ***,we aimed to identify potential prognostic ***,oS,CSS,and MFS were calculated with the Kaplan-Meier method and the log-rank *** and multivariate Cox regression models were performed to explore between-group differences in survival outcome *** A total of 301 consecutive patients were *** these,93(33.6%)received ART and 186(66.4%)SRT;22 patients were excluded due to residual macroscopic disease or local recurrence in the surgical *** this subgroup(n=93),43 patients(46.2%)were Gleason score(GS)≤6,44(47.3%)GS 7,and 6(6.5%)GS≥8;clinical stage

关键词： Prostate cancer Postoperative radiotherapy Dose intensified Radiation dose Biochemical relapse free survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

半干旱区盐湖生态系统对灌溉和气候变化的响应西班牙Ebro盆地中部Salada Chiprana的历史

引用

AMBIo－人类环境杂志 2000年第6期29卷 344-350页

作者： BlasL.valero-Garcés Ana Navas Javier Machin Tony Stevenson Basil Davis 鲁春霞生态研究所 Estacion Experimental de Aula Dei-CSIC Apdo 202 50080 Zaragoza Spain。纽卡斯尔大学普朗克生物地球化学研究所

为了充分管理半干旱地区脆弱多变的环境,在比人类记录更长的时间尺度上把人类影响与气候或者其他的环境影响区分开来是至关重要的。我们应用孢粉、炭屑、沉积学、地球化学和放射性测年技术方法对西班牙Ebro盆地中部的Salada Chiprana盐... 详细信息

为了充分管理半干旱地区脆弱多变的环境,在比人类记录更长的时间尺度上把人类影响与气候或者其他的环境影响区分开来是至关重要的。我们应用孢粉、炭屑、沉积学、地球化学和放射性测年技术方法对西班牙Ebro盆地中部的Salada Chiprana盐湖沉积岩心进行了调查研究。结果表明,全新世晚期季节性的干盐湖在几个世纪以前迅速向永久性盐湖演化。湖沼的发育与农业生产活动变化有关,这就提供了从15世纪以来灌溉对湖泊水量平衡强烈影响的证据。本研究还显示,西班牙唯一的、永久性的、相对较深的、盐化度极高的盐湖是人类与自然景观长期相互作用的产物。

关键词：盐湖生态系统灌溉气候变化半干旱区湖泊

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：