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基于脑MRI髓鞘形成的深度学习预测新生儿和婴儿的脑龄

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国际医学放射学杂志 2023年第1期46卷 112-112页

作者： J.V.Chen G.Chaudhari C.P.Hess o.a.glenn L.P.Sugrue A.M.Rauschecker 袁园

摘要根据妊娠校正年龄（GCA）在T1WI和T2WI上评估脑的髓鞘化,需要在了解正常髓鞘形成阶段基础上对脑进行主观观察。目的建立基于MRI脑髓鞘形成来预测新生儿和

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Advances in teleophthalmology and artificial intelligence for diabetic retinopathy screening:a narrative review

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Annals of Eye Science 2024年第2期9卷 24-37页

作者： Tanvi Chokshi Maria Jessica Cruz Jonathon Ross glenn Yiu Tschannen Eye Institute Department of OphthalmologyUniversity of CaliforniaDavis HealthSacramentoCAUSA Department of Research College of MedicineCalifornia Northstate UniversityElk GroveCAUSA

Background and objective:Advances in teleophthalmology and artificial intelligence(AI)for diabetic retinal screening is of growing public health ***,only 30–40%of patients with diabetes adhere to recommended diabetes screening *** enhance early detection and reduce vision threatening complications,there has been a growing number of teleophthalmology programs and novel AI algorithms with the aim to improve eye care *** purpose of this review is to assess current literature on teleophthalmology and AI for use in diabetic retinopathy(DR)screening,and to discuss advances and barriers to these innovative ***:Literature review involving teleophthalmology and AI for DR screening,with focus on the past *** Content and Findings:Teleophthalmology has demonstrated the ability to increase DR screening rates,enable earlier eye care access,and reduce healthcare *** AI-based DR screening programs appear accurate and effective,but detection of other ocular pathologies is still under development and not yet approved in the United ***,technological,financial,and legal barriers limit widespread adoption and long-term sustainability of teleophthalmology ***:The use of teleophthalmology and AI algorithms expands eye care access and helps prevent vision loss from DR and potentially other sight threatening *** in the process utilized for arriving at a particular diagnosis or decision to refer,often referred to as the“black box”,remains a multifaceted issue within the field of telemedicine for developing trust and improving patient-centered outcomes.

关键词： Teleophthalmology artificial intelligence(AI) diabetic retinopathy(DR) screening public health

Antisense oligonucleotides provide optimism to the therapeutic landscape for tauopathies

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Neural Regeneration Research 2025年第3期20卷 803-804页

作者： glenn A.Harris Lauren R.Hirschfeld Rainwater Charitable Foundation Fort WorthTXUSA

Tauopathies are a group of neurodegenerative diseases characterized by abnormal metabolism of the misfolded tau protein. Tau is encoded by the microtubule-associated protein tau gene(MAPT) and can be classified as either 3-repeat(3R) or 4-repeat(4R) based on the number of repeat domains from alternative splicing of exon 10 of the MAPT gene.

关键词： tau metabolism diseases

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Stability analysis of a time-delayed Van der Pol–Helmholtz–Duffing oscillator in fractal space with a non-perturbative approach

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Communications in Theoretical Physics 2024年第4期76卷 22-31页

作者： Yusry o El-Dib Department of Mathematics Faculty of EducationAin Shams UniversityRoxyCairoEgypt

The time-delayed fractal Van der Pol–Helmholtz–Duffing(VPHD)oscillator is the subject of this paper,which explores its mechanisms and highlights its stability *** time-delayed technologies are currently garnering significant attention,the focus of this research remains crucially relevant.A non-perturbative approach is employed to refine and set the stage for the system under *** innovative methodologies introduced yield an equivalent linear differential equation,mirroring the inherent nonlinearities of the ***,the incorporation of quadratic nonlinearity into the frequency formula represents a cutting-edge *** analytical solution's validity is corroborated using a numerical *** conditions are ascertained through the residual Galerkin ***,it is observed that the delay parameter,in the context of the fractal system,reverses its stabilizing influence,impacting both the amplitude of delayed velocity and the *** analytical solution's precision is underscored by its close alignment with numerical ***,the study reveals that fractal characteristics emulate damping *** its applicability across diverse nonlinear dynamical systems,this non-perturbative approach emerges as a promising avenue for future research.

关键词： Van der Pol-Helmholtz-Duffing oscillator fractal space time-delay non-perturbative approach stability analysis El-Dib's frequency formula

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Sensing nanoscale electromagnetic forces when the heat is on

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National Science Review 2024年第7期11卷 64-65页

作者： Eric o.Potma Department of Chemistry University of California

In scanning probe microscopy(SPM),a sharp tip scans across a sample to produce an image with nanometer-scale resolution or better. SPM contrast is derived from the physical interplay between the tip and the sample. A special class of SPM techniques measures forces when the tip–sample junction is illuminated by an external light source. Photo-induced forces can be sensitive to the optical properties of the sample, thus enabling nanoscale imaging with spectroscopic,material-specific contrast.

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Making topological protein links using enzymatic reactions

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National Science Review 2024年第3期11卷 50-51页

作者： Roger Castells-Graells Todd o.Yeates Department of Chemistry and Biochemistry University of California UCLA-DoE Institute for Genomics and Proteomics

Proteins are exceedingly complex molecules though, at their heart, they are essentially linear polymers. Pull at their ends and one obtains an extended backbone. While that is true in most cases, some natural proteins... 详细信息

关键词： DESIGN

A synthetic microbial community used as a bioinoculant can overcome rice production constraints in acid soils

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Science China(Life Sciences) 2024年第5期67卷 1085-1086页

作者： Maureen o’Callaghan Shengjing Shi Resilient Agriculture Group AgResearchLincolnChristcurch 8140New Zealand

A customised synthetic microbial community(SynCom)composed of carefully selected rhizosphere-competent bacterial strains improved rice growth,yield and resistance to soil acidity and Al toxicity.

关键词： soil soils rhizosphere

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Valorization of Tree Bark-Derived Suberin in Applications for the Bio-Based Composites Industry–A Recent Review

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Journal of Renewable Materials 2024年第6期12卷 1029-1042页

作者： Aleksandra Jeżo Institute of Wood Sciences and Furniture SGGWNowoursynowska St.159Warsaw02-776Poland

Bark extracts are sustainable sources of biopolymers and hold great promise for replacing fossil fuel-based polymers,for example,in wood-based *** addition to primary and secondary metabolites,tree bark also contains suberin,which plays a major role in protecting the tree from environmental *** is a natural aliphatic-aromatic cross-linked polyester present in the cell walls of both normal and damaged external tissues,the main component of which are long-chain aliphatic *** main role as a plant ingredient is to protect against microbiological factors and water *** of the most important suberin monomers are suberin fatty acids,known for their hydrophobic and barrier ***,due to the diverse chemical composition of suberin,it is an attractive alternative to hydrocarbon-based *** its potential is recognized,it is not widely used in biocomposites technology,including wood-based composites and the polymer *** article will discuss the current knowledge about the potential of suberin and its components in biocomposites technology,which will include surface finishes,composite adhesives and polymer blends.

关键词： Suberin suberinic acids wood composites biocomposites biopolyester

Investigation of the effects of radial clearance on the screw conveyor performances for different inclinations

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Particuology 2024年第9期92卷 72-80页

作者： Berna Bolat Birgül Aşçıoğlu Temiztaş Enes Sezer Department of Mechanical Engineering Yıldız Technical University34349BeşiktaşİstanbulTurkey

Screw conveyors are widely used for bulk material *** study investigates the critical role of radial clearance,the gap between the screw and the conveyor body,on performance across various inclination *** Discrete Element Method(DEM)is employed to analyze the effects of different radial clearances on conveyor performance for concrete aggregate and sand as bulk *** efficiencies and capacity losses serve as key performance indicators,quantitatively assessed for each radial clearance and inclination *** validation is conducted to corroborate the *** the study,the optimal radial clearance was identified as 1.5 to 3 times of the particle *** optimal clearance minimizes the material jamming and increases the performance for screw conveyors with different inclinations and bulk material types as a result.

关键词： Screw conveyors Radial clearance Discrete element method(DEM) Volumetric efficiency Conveyor performance