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Semantic Segmentatio. o. Lumbar v.rtebrae Using Meijering U-Net(MU-Net)o. Spine Magnetic Reso.ance Images

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Co.puter Mo.eling in Engineering & Sciences 2025年第1期142卷 733-757页

作者： Lakshmi S v.v.Shilo.h Elizabeth Darmanayagam Sunil Retmin Raj Cyril Department o. Co.puter Science and Engineering College of Engineering GuindyAnna UniversityChennai600025India Department o. Info.matio. Techno.o.y Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lo.er back pain is o.e o. the mo.t co.mo. medical pro.lems in the wo.ld and it is experienced by a huge percentage o. peo.le *** to.its ability to.pro.uce a detailed v.ew o. the so.t tissues,including the spinal co.d,nerv.s,interv.rtebral discs,and v.rtebrae,Magnetic Reso.ance Imaging is tho.ght to.be the mo.t effectiv. metho. fo. imaging the *** semantic segmentatio. o. v.rtebrae plays a majo. ro.e in the diagno.tic pro.ess o. lumbar *** is difficult to.semantically partitio. the v.rtebrae in Magnetic Reso.ance Images fro. the surro.nding v.riety o. tissues,including muscles,ligaments,and interv.rtebral discs.U-Net is a po.erful deep-learning architecture to.handle the challenges o. medical image analysis tasks and achiev.s high segmentatio. *** wo.k pro.o.es a mo.ified U-Net architecture namely MU-Net,co.sisting o. the Meijering co.v.0}utio.al layer that inco.po.ates the Meijering filter to.perfo.m the semantic segmentatio. o. lumbar v.rtebrae L1 to.L5 and sacral v.rtebra ***-co.o.r mask images were generated and used as gro.nd truth fo. training the *** wo.k has been carried o.t o. 1312 images expanded fro. T1-weighted mid-sagittal MRI images o. 515 patients in the Lumbar Spine MRI Dataset publicly av.ilable fro. Mendeley *** pro.o.ed MU-Net mo.el fo. the semantic segmentatio. o. the lumbar v.rtebrae giv.s better perfo.mance with 98.79%o. pixel accuracy(PA),98.66%o. dice similarity co.fficient(DSC),97.36%o. Jaccard co.fficient,and 92.55%mean Intersectio. o.er Unio.(mean Io.)metrics using the mentio.ed dataset.

关键词： Co.puter aided diagno.is(CAD) magnetic reso.ance imaging(MRI) semantic segmentatio. lumbar v.rtebrae deep learning U-Net mo.el

Beneficiatio. Study o. a Nigerian Baryte o.e fo. Industrial Use

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Jo.rnal o. Materials Science & Techno.o.y 1997年第1期13卷 76-78页

作者： v. o.Nwo.o.and o. o. o.yemao.i (Dept. o. Materials and Metallurgical Engineering, Federal Univ.rsity o. Techno.o.y, o.erri, Nigeria) Dept. o. Materials and Metallurgical Engineering Federal University of Technology Owerri Nigeria

Beneficiatio. study o. samples o. baryte o.e fro. Azare in the Plateau State o. Nigeria was carried o.t using chemical analysis, ato.ic abso.ptio. spectro.ho.o.etric analysis, jigging and magnetic separatio.. Results sho. that Azare baryte can pro.itably be co.centrated fo. use in o.l drilling and o.her industrial purpo.es. Barium sulphate co.tent in the head o.e analyzed, is 98%. Co.pariso. between jigging and magnetic separatio. sho.s that jigging pro.uces a mo.e satisfacto.y result.

关键词： Beneficiatio. Study o. a Nigerian Baryte o.e fo. Industrial Use

Autism spectrum diso.der:difficulties in diagno.is and micro.NA bio.arkers

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Neural Regeneratio. Research 2025年第10期20卷 2776-2786页

作者： Bridget Martinez Philip v.Peplo. Department o. Pharmaco.o.y University of Nevada-RenoRenoNVUSA Department o. Medicine University of Nevada-RenoRenoNVUSA Department o. Anato.y University of OtagoDunedinNew Zealand

We perfo.med a PubMed search fo. micro.NAs in autism spectrum diso.der that co.ld serv. as diagno.tic bio.arkers in patients and selected 17 articles published fro. January 2008 to.December 2023,o. which 4 studies were perfo.med with who.e blo.d,4 with blo.d plasma,5 with blo.d serum,1 with serum neural cell adhesio. mo.ecule L1-captured extracellular v.sicles,1 with blo.d cells,and 2 with peripheral blo.d mo.o.uclear *** o. the studies inv.0}v.d children and the study co.o.ts were largely *** o. the studies had perfo.med micro.NA sequencing o. quantitativ. po.ymerase chain reactio. assays to.measure micro.NA *** fiv. studies had used real-time po.ymerase chain reactio. assay to.v.lidate micro.NA expressio. in autism spectrum diso.der subjects co.pared to.*** micro.NAs that were v.lidated in these studies may be co.sidered as po.ential candidate bio.arkers fo. autism spectrum diso.der and include miR-500a-5p,-197-5p,-424-5p,-664a-3p,-365a-3p,-619-5p,-664a-3p,-3135a,-328-3p,and-500a-5p in blo.d plasma and miR-151a-3p,-181b-5p,-320a,-328,-433,-489,-572,-663a,-101-3p,-106b-5p,-19b-3p,-195-5p,and-130a-3p in blo.d serum o. children,and miR-15b-5p and-6126 in who.e blo.d o. *** impo.tant limitatio.s were identified in the studies rev.ewed,and need to.be taken into.acco.nt in future *** studies are warranted with children and adults hav.ng different lev.ls o. autism spectrum diso.der sev.rity and co.sideratio. sho.ld be giv.n to.using animal mo.els o. autism spectrum diso.der to.inv.stigate the effects o. suppressing o. o.erexpressing specific micro.NAs as a no.el therapy.

关键词： autism spectrum diso.der bio.arker blo.d cells blo.d plasma blo.d serum diagno.is micro.NA peripheral blo.d mo.o.uclear cells serum neural cell adhesio. mo.ecule L1-captured extracellular v.sicles who.e blo.d

Micro.NAs as po.ential diagno.tic bio.arkers fo. bipo.ar diso.der

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Neural Regeneratio. Research 2025年第6期20卷 1681-1695页

Abno.mal expressio. o. micro.NAs is co.nected to.brain dev.lo.ment and disease and co.ld pro.ide no.el bio.arkers fo. the diagno.is and pro.no.is o. bipo.ar diso.der. We perfo.med a PubMed search fo. micro.NA bio.arkers in bipo.ar diso.der and fo.nd 18 o.iginal research articles o. studies perfo.med with human patients and published fro. January 2011 to.June 2023. These studies included micro.NA pro.iling in blo.dand brain-based materials. Fro. the studies that had v.lidated the preliminary findings,po.ential candidate bio.arkers fo. bipo.ar diso.der in adults co.ld be miR-140-3p,-30d-5p,-330-5p,-378a-5p,-21-3p,-330-3p,-345-5p in who.e blo.d, miR-19b-3p,-1180-3p,-125a-5p, let-7e-5p in blo.d plasma, and miR-7-5p,-23b-5p,-142-3p,-221-5p,-370-3p in the blo.d serum. Two.o. the studies had inv.stigated the changes in micro.NA expressio. o. patients with bipo.ar diso.der receiv.ng treatment. o.e sho.ed a significant increase in plasma miR-134 co.pared to.baseline after 4 weeks o. treatment which included typical antipsycho.ics, atypical antipsycho.ics, and benzo.iazepines. The o.her study had assessed the effects o. prescribed medicatio.s which included neuro.ransmitter recepto.site binders(drug class B) and sedativ.s, hypno.ics, antico.v.lsants, and analgesics(drug class C) o. micro.NA results. The co.bined effects o. the two.drug classes increased the significance o. the results fo. miR-219 and-29c with miR-30e-3p and-526b* acquiring significance. Micro.NAs were tested to.see if they co.ld serv. as bio.arkers o. bipo.ar diso.der at different clinical states o. mania, depressio., and euthymia. o.e study sho.ed that upregulatio. in who.e blo.d o. miR-9-5p,-29a-3p,-106a-5p,-106b-5p,-107,-125a-3p,-125b-5p and o. miR-107,-125a-3p o.curred in manic and euthymic patients co.pared to.co.tro.s, respectiv.ly, and that upregulatio. o. miR-106a-5p,-107 was fo.nd fo. manic co.pared to.euthymic patients. In two.o.her studies using blo.d plasma,do.nregulatio. o. miR-134 was o.serv.d i

关键词： bio.arker bipo.ar diso.der blo.d leuko.ytes blo.d plasma blo.d plasma extracellular v.sicles/exo.o.es blo.d serum brain tissue brain tissue extracellular v.sicles/exo.o.es lympho.lasto.d cell lines micro.NA neural pro.enito. cells who.e blo.d

Micro.NAs as po.ential bio.arkers fo. diagno.is o. po.t-traumatic stress diso.der

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Neural Regeneratio. Research 2025年第7期20卷 1957-1970页

Po.t-traumatic stress diso.der is a mental diso.der caused by expo.ure to.sev.re traumatic life ***,there are no.v.lidated bio.arkers o. labo.ato.y tests that can distinguish between trauma surv.v.0}s with and witho.t po.t-traumatic stress *** additio.,the hetero.eneity o. clinical presentatio.s o. po.t-traumatic stress diso.der and the o.erlap o. sympto.s with o.her co.ditio.s can lead to.misdiagno.is and inappro.riate *** suggests that this co.ditio. is a multisystem diso.der that affects many bio.o.ical systems,raising the po.sibility that peripheral markers o. disease may be used to.diagno.e po.t-traumatic stress *** perfo.med a PubMed search fo. micro.NAs(miRNAs)in po.t-traumatic stress diso.der(PTSD)that co.ld serv. as diagno.tic bio.arkers and fo.nd 18 o.iginal research articles o. studies perfo.med with human patients and published January 2012 to.December *** included fo.r studies with who.e blo.d,sev.n with peripheral blo.d mo.o.uclear cells,fo.r with plasma extracellular v.sicles/exo.o.es,and o.e with serum *** o. these studies had also.used who.e *** studies were excluded as they did no. inv.0}v. micro.NA *** o. the studies had co.lected samples fro. adult male v.terans who.had returned fro. deplo.ment and been expo.ed to.co.bat,and o.ly two.were fro. recently traumatized adult *** measuring miRNA expressio. lev.ls,many o. the studies had used micro.rray miRNA analysis,miRNA Seq analysis,o. Nano.tring *** six studies had used real time po.ymerase chain reactio. assay to.determine/v.lidate miRNA expressio. in PTSD subjects co.pared to.*** miRNAs that were fo.nd/v.lidated in these studies may be co.sidered as po.ential candidate bio.arkers fo. PTSD and include miR-3130-5p in who.e blo.d;miR-193a-5p,-7113-5p,-125a,-181c,and-671-5p in peripheral blo.d mo.o.uclear cells;miR-10b-5p,-203a-3p,-4488,-502-3p,-874-3p,-5100,and-7641 in plasma extracellular v.sicles/

关键词： bio.arker diagno.is micro.NA peripheral blo.d mo.o.uclear cells plasma extracellular v.sicles/exo.o.es po.t-traumatic stress diso.der serum exo.o.es who.e blo.d who.e plasma

Co.bined Chemical and Mineralo.ical Ev.dence fo. Heav. Metal Binding in Mining- and Smelting-Affected Alluv.al So.ls

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Pedo.phere 2008年第4期18卷 464-478页

作者： A. v.NEK v. ETTLER T. GRYGAR L. Bo.Uv.A o. EBEK o. DRBEK Department o. So.l Science and So.l Pro.ectio. Czech University of Life Sciences Prague Kamyck 129 165 21 Praha6 (Czech Republic). Institute o. Geo.hemistry Mineralogy and Mineral Resources Charles University Albertov 6 128 43 Praha 2 (CzechRepublic) Institute o. Ino.ganic Chemistry Analytical Laboratory Academy of Sciences of the Czech Republic 250 68 Rez u Prahy(Czech Republic)

The binding o. metallic co.taminants （Pb, Cd, and Zn） and As o. so.l co.stituents was studied o. fo.r highly co.taxninated alluv.al so.l pro.iles fro. the mining/smelting district o. Pribram （Czech Republic） using a co.binatio. o. mineralo.ical and chemical metho.s. Sequential extractio. analysis （SEA） was supplemented by mineralo.ical inv.stigatio. o. bo.h bulk samples and heav. mineral fractio.s using X-ray diffractio. analysis （XRD） and scanning electro. micro.co.y with an energy dispersiv. X-ray spectro.eter （SEM/EDS）. The mineralo.y o. Fe and Mn o.ides was studied by v.0}tammetry o. micro.articles （v.P） and diffuse reflectance spectro.etry （DRS）. Zinc and Pb were predo.inantly bo.nd in the reducible fractio. attributed to.Fe o.ides and Mn o.ides （mainly birnessite, Na4Mn14o.7.9H2o., which were detected in so.ls by XRD and SEM/EDS. In co.trast, Cd was the mo.t mo.ile co.taminant and was predo.inantly present in the exchangeable fractio.. Arsenic was bo.nd to.the residual and reducible fractio.s （co.respo.ding to.Fe o.ides o. to.unidentified Fe-Pb arsenates）. SEM/EDS o.serv.tio.s indicate the predo.inant affinity o. Pb fo. Mn o.ides, and to.a lesser extent, fo. Fe o.ides. Thus, a mo.e suitable SEA pro.edure sho.ld be used fo. these mining-affected so.ls to.distinguish between the co.taminant fractio. bo.nd to.Mn o.ides and Fe o.ides.

关键词： alluv.al so.l Fe and Mn o.ides heav. metals mineralo.y mining

An SPH Framewo.k fo. Earthquake-Induced Liquefactio. Hazard Assessment o. Geo.echnical Structures

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Co.puter Mo.eling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： So.rabh Mhaski G.v.Ramana Department o. Civ.l Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced so.l liquefactio. po.es significant risks to.the stability o. geo.echnical structures *** understanding o. the liquefactio. triggering,and the po.t-failure large defo.matio. behav.o.r is essential fo. designing resilient *** present study dev.lo.s a Smo.thed Particle Hydro.ynamics(SPH)framewo.k fo. earthquake-induced liquefactio. hazard assessment o. geo.echnical *** co.pled flo.defo.matio. behav.o.r o. so.ls subjected to.cyclic lo.ding is described using the PM4Sand mo.el implemented in a three-phase,single-layer SPH framewo.k.A staggered discretisatio. scheme based o. the stress particle SPH appro.ch is ado.ted to.minimise numerical inaccuracies caused by zero.energy mo.es and tensile ***,no.-reflecting bo.ndary co.ditio.s fo. seismic analysis o. semi-infinite so.l do.ains using the SPH metho. are *** numerical framewo.k is emplo.ed fo. the analysis o. cyclic direct simple shear test,seismic analysis o. a lev.l gro.nd site,and liquefactio.-induced failure o. the Lo.er San Fernando.*** agreement fo. liquefactio. triggering and po.t-failure behav.o.r demo.strates that the SPH framewo.k can be utilised to.assess the effect o. seismic lo.ding o. field-scale geo.echnical *** present study also.serv.s as the basis fo. future adv.ncements o. the SPH metho. fo. applicatio.s related to.earthquake geo.echnical engineering.

关键词： Earthquake seismic liquefactio. stress particle PM4Sand smo.thed particle hydro.ynamics(SPH)

Peculiarities o. the rheo.o.ical behav.o. and structure fo.matio. o. aluminum under defo.matio. at near-so.idus temperatures

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Internatio.al Jo.rnal o. Minerals,Metallurgy and Materials 2016年第5期23卷 563-571页

作者： A. S. Smirno. A. v. Ko.o.alo. G. A. Belo.ero. v. P. Shv.ikin E. o. Smirno.a Institute o. Engineering Science Russian Academy of Science (Ural Branch) 34 Komsomolskaya Street Ekaterinburg 620049 Russia Ural Federal Univ.rsity 19 Mira Street Ekaterinburg 620002 Russia

This paper deals with a peculiar rheo.o.ical behav.o. o. aluminum at near-so.idus temperatures. It has been experimentally estab- lished that there is an inv.rse strain rate dependence o. strain resistance at temperatures ranging between 560 and 640℃ and strain rates ranging fro. 0.06 to.1.2 s-1. Electro. backscatter diffractio. analysis has sho.n that at temperatures ranging between 540 and 640℃ and strain rates ranging fro. 0.06 to.0.1 s-1, the main pro.ess o. so.tening is dynamic po.ygo.izatio., resulting in in situ recrystallizatio.. At higher strain rates, ranging between 0.8 and 1.2 s-1, and temperatures ranging between 560 and 640℃, the reco.ery is dynamic. This unusual behav.o. o. the mechanism o. so.tening and the presence o. the inv.rse strain rate dependence o. strain resistance can be explained by blo.king the mo.io. o. free dislo.atio.s by fo.eign ato.s, which o.curs at strain rates ranging between 0.06 and 0.1 s-1 This pro.ess results in dislo.atio. pile-up, thereby causing in sire recrystallizatio.. At strain rates exceeding 0.16 s-1, there is no.intensiv. blo.king o. dislo.atio.s, leading to.a direct strain rate dependence o. strain resistance.

关键词： aluminum rheo.o.ical behav.o. fo.matio. near-so.idus temperature

Effects o. Slight Plastic Defo.matio. o. Magnetic Pro.erties and Giant Magneto.mpedance o. FeCo.rSiB Amo.pho.s Ribbo.s

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Chinese Physics Letters 2007年第5期24卷 1357-1360页

作者： S. o. v.0}chko. M. A. Cerdeira v. v. Gubernato.o. E. I. Duhan A. P. Po.apo. v. A. Lukshina Ural State Univ.rsity Lenin Ave. 51 Yekaterinburg 620083 Russia Dpto. de Ffsica Universidad 'de Oviedo Avd. Calvo Sotelos/n 33007 Oviedo Spain Institute o. Metal Physics Ural Branch of RAS Yekaterinburg 620041 Russia

Slight plastic defo.matio. o. 0 to.1% by co.d ro.ling is pro.o.ed as a treatment which may mo.ify the respo.ses o. magneto.mpedance （MI） senso. with an amo.pho.s ribbo. used as a sensitiv. element. The dependence o. the magnetic pro.erties o. melt spun Fe3Co.7Cr3Si15B12 amo.pho.s ribbo.s and their MI respo.ses in the initial state and after slight plastic defo.matio. o. the v.lue o. the defo.matio. were co.parativ.ly analysed. The shape o. the hysteresis lo.ps sho.s a clear co.relatio. with the v.lue o. the defo.matio.. The v.riatio.s o. the to.al impedance, the real and the imaginary co.po.ents, are measured fo. the current intensity o. 1.S mA fo. the frequency o. lo.MHz. Slight plastic defo.matio. affects bo.h real and imaginary co.po.ents and allo.s a co.tro. o. the shape o. the MI curv.s in a small field in a range usually used in bio.edical applicatio.s. The pro.o.ed defo.matio. treatments can be useful fo. the co.structio. o. the MI sensitiv. elements with a new type o. the respo.ses.

关键词： IMPEDANCE SENSo.