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The impact o. perso.ality o. the success o. pro.pecting.behavio. in chang.ng.landscapes

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Current Zo.lo.y 2015年第3期61卷 557-568页

作者： Jo.n Curtis BURKHALTER Nina H. FEFFERMAN Julie L. lockwood g.aduate Pro.ram in Eco.o.y and Evo.utio. Department of Ecology Evolution and Natural Resources Rutgers University 14College Farm Rd. New Brunswick NJ 08901 USA

Perso.ality can play a larg. ro.e in dispersal decisio.s, influencing.ho. each individual estimates and values ex- pected co.ts versus benefits o. ventnring.o.t to.explo.e the unkno.n. We co.trast the impact o. persistence o. fitness using.deci- sio. theo.y mo.els to.examine the relative success o. pro.pecting.mo.ement （which is a widespread behavio. used by animals to.explo.e available breeding.habitat befo.e determining.where to.settle） in different landscapes amo.g.individuals with different perso.alities. While evaluating.trends in the co.ts and benefits o. mo.ement we pro.ide a quantifiable measure o. the impacts o. relative tenacity in pro.pecting.behavio. o. fitness g.ins/lo.ses. o.r mo.el results predict that, reg.rdless o. landscape co.po.i- tio., individuals with g.eater tenacity in pro.pecting.strateg. have reduced fitness g.ins relative to.individuals who.are mo.e willing.to.bo.h initiate no.el strateg.es, but then also.abando. the new strateg. rapidly if initial search do.s no. seem fruitful. We sho. that fitness g.ins fro. cho.sing.an appro.riate pro.pecting.strateg. （i.e. abando.ing.po.r habitat o. staying.in rich habitat） can be very hig., indicating.a po.entially larg. influence fro. perso.ality o. fitness. Impo.tantly, the mo.el predicts that relative fitness g.ins are hig.ly dependent o. the availability o. hig. quality habitat in the landscape, even if the difference under varying.fitness o.tco.es between po.r and rich habitat was substantial

关键词： Pro.pecting Tradeo.f Mo.ement Decisio. theo.y Perso.ality Behavio.

Epito.e mapping.o. Weg.ner's g.anulo.ato.is auto.ntig.n pro.einase 3

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Chinese Medical Jo.rnal 2001年第7期114卷 88-91,110-111页

作者：黄真 Martin lockwood 北京大学第一医院物理医学康复科北京100034 Department o. Medicine University of CambridgeSchool of Clinical MedicineAddenbrooke’s Hospital

Abstract:o.jective To.map the epito.es o. Weg.ner's g.anulo.ato.is auto.ntig.n pro.einase *** Antig.nicity o. pro.einase 3 was studied with Western blo. analysis in which pro.einase 3 was prepared under reducing.and no.-reducing.co.ditio.s. Two.anti-pro.einase 3 mo.o.lo.al antibo.ies, HZ1F12 and HZ1H3, were used to.inhibit each o.her and to.inhibit 22 anti-pro.einase 3 po.itive sera fro. patients with Weg.ner's g.anulo.ato.is in co.petitive inhibitio. enzyme-linked immuno.o.bent assays (ELISA) and Western blo. analysis. Results All mo.o.lo.al antibo.ies and patient sera reco.nized pro.einase 3 under no.-reducing.co.ditio.s in Western blo. analysis. HZ1F12 was inhibited 74% by HZ1H3. 10/22 (46%) sera were co.pletely o. partially inhibited by HZ1F12; 9/22 (41%) sera were partially inhibited by HZ1H3; and 6/22 (27%) were inhibited by bo.h mo.o.lo.al antibo.ies. In inhibitio. Western blo. analysis, the binding.o. patient sera to.pro.einase 3 co.ld be inhibited by HZ1F12. Co.clusio.s The epito.es o. Weg.ner's g.anulo.ato.is auto.ntig.n were co.fo.matio.al. Anti-pro.einase 3 mo.o.lo.al HZ1F12 and HZ1H3 reco.nized similar o. o.erlapping.epito.es o. the pro.einase 3 mo.ecule. Epito.es o. pro.einase 3 reco.nized by anti-pro.einase 3 po.itive sera were no. restricted.

关键词： vasculitis · Weg.ner's g.anulo.ato.is · pro.einase 3 · anti neutro.hil cyto.lasmic auto.ntibo.ies · epito.e

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应用气象模式对高地沼泽土壤缺水量的估算

气象科技 1989年第6期17卷 67-74页

作者： J.g.lockwood 毛光伶英国利兹大学

1.前言估算相对较湿较冷的英国高地沼泽的土壤缺水量(So.l mo.sture deficits, SMD),对于水文工作者的河流模拟及农业工作者的沼泽地管理都是有所帮助的。气象模式,如英国气象局降水和蒸发估算系统(Mo.ECS),被广泛地用于估算土壤缺水量。

关键词：缺水量气象模式中子法 mo.sture 水文工作者农业工作者田间持水量冠层阻力枯枝落叶层气孔阻力

o.servatio.s o. the step-like accelerating.pro.esses o. co.d io.s in the reco.nectio. layer at the dayside mag.eto.ause

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Science Bulletin 2018年第1期63卷 31-37页

作者： Qing.e Zhang.Michael lockwood Jo.n C.Fo.ter Qiug.ng.Zo.g.Malco.m W.Dunlo. Shunro.g.Zhang.Jo.an Mo.n Beichen Zhang Shando.g.Pro.incial Key Labo.ato.y o. o.tical Astro.o.y and So.ar-Terrestrial Enviro.ment Institute of Space SciencesShandong UniversityWeihai 264209China Department o. Meteo.o.o.y University of ReadingReading RG6 6BBUK MIT Haystack o.servato.y WestfordMA 01886USA Scho.l o. Earth and Space Sciences Peking UniversityBeijing 100087China Space Sciences Divisio. SSTDRutherford Appleton LaboratoryDidcot OX11 OQXUK Department o. Physics University of OsloBlindern 0316OsloNorway So. Key Labo.ato.y fo. Po.ar Science Polar Research Institute of ChinaShanghai 200136China

Co.d io.s o. plasmaspheric o.ig.n have been o.served to.abundantly appear in the mag.eto.pheric side o. the Earth's mag.eto.ause. These co.d io.s co.ld affect the mag.etic reco.nectio. pro.esses at the mag.eto.ause by chang.ng.the Alfvén velo.ity and the reco.nectio. rate, while they co.ld also.be heated in the reco.nectio. layer during.the o.g.0}ng.reco.nectio.s. We repo.t in situ o.servatio.s fro. a partially cro.sing.o. a reco.nectio. layer near the subso.ar mag.eto.ause. During.this cro.sing. step-like accelerating.pro.esses o. the co.d io.s were clearly o.served, sug.esting.that the inflo. co.d io.s may be separately accelerated by the ro.atio. disco.tinuity and slo. sho.k inside the reco.nectio. layer.

关键词： Co.d io.s Mag.etic reco.nectio. Io. acceleratio.s Mag.eto.ause

Efficacy o. Perio.erative Intraveno.s Lido.aine fo. Multimo.al Analg.sia

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o.en Jo.rnal o. Anesthesio.o.y 2020年第9期10卷 299-312页

作者： Nishita lockwood Lo.a Misra Department o. Anesthesio.o.y Mayo Clinic Arizona Phoenix AZ USA

g.ven the rising.incidence o. o.io.d misuse and o.io.d-related deaths wo.ldwide, it is imperative to.find no.o.io.d analg.sic adjuncts fo. perio.erative pain manag.ment. Perio.erative o.io.d expo.ure in o.io.d-naïve patients fo. even mino. surg.cal pro.edures may result in sig.ificant o.io.d dependence. Altho.g. the use o. intraveno.s lido.aine in the perio.erative perio. is no. no.el, recently it has been pro.o.ed as an impo.tant adjunct to.multimo.al analg.sia. In additio. to.impro.ing.acute pain, lido.aine may reduce the incidence o. chro.ic po.t-o.erative pain syndro.e (CPPS), impro.e bo.el functio., and decrease po.t-o.erative nausea and vo.iting.(Po.V) thereby speeding.up the po.t-o.erative reco.ery pro.ess. Furthermo.e, lido.aine has efficacy in a variety o. pro.edures including.abdo.inal, g.neco.o.ical, and uro.o.ical surg.ries. The aim o. this narrative review is to.evaluate the effects o. intraveno.s lido.aine co.pared to.traditio.al analg.sic metho.s o. po.t-o.erative pain co.tro. and reco.ery fo. vario.s surg.cal pro.edures.

关键词： Pain Manag.ment o.io.d Addictio. Intrao.erative Pain Co.tro. No.-o.io.d Analg.sia

Using.Dichro.sm to.Elucidate the Nature o. Mag.etic Interactio.s in Antiferro.ag.etic Materials

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发光学报 2008年第4期29卷 627-632页

作者： K R Ho.fman D J lockwood Department o. Physics Whitman CollegeWalla WallaWA 99362 USA Institute fo. Micro.tructural Sciences National Research CouncilOttawaONK1A 0R6Canada

William(familiarly kno.n as Bill by all his co.leag.es) Yen's life-lo.g.scientific interest in the mag.etic pro.erties o. rutile structured antiferro.ag.etic materials(AFMs) beg.n with his invo.vement in the disco.ery in 1965 o. the mag.o. sidebands o. MnF2 in o.tical abso.ptio.[1].A basic o.tline o. this disco.ery is g.ven elsewhere in this special issue o. the Chinese Jo.rnal o. Luminescence[2].A narrative discussio. o. events leading.to.this disco.ery appears in a co.tributio. written by Bill and Ro.ert White fo. a special editio. o. Lo. Temperature Physics o. Antiferro.ag.etism[3].A quo.e fro. that remembrance hig.lig.ts a quality that remained with Bill thro.g.o.t his career: "The identificatio. o. these sidebands by a pair o. yo.ng.students and two.po.t-do.s illustrates ho. serendipity,a to.ch o. g.0}d luck and reckless yo.thful enthusiasm o.ten plays a ro.e in scientific disco.ery".Bill's fo.ever yo.thful enthusiasm co.pled with creative insig.ts into.current research questio.s led to.numero.s pio.eering.disco.eries thro.g.o.t his *** paper reviews Bill's co.tributio.s to.develo.ing.techniques to.explo.t dichro.sm to.study the mag.etic pro.erties o. ***'s publicatio.s in this area span mo.e than 30 years,fro. 1971 to.2004.

关键词：二向色性磁振子交互作用反铁磁性

Peptide Variant Detectio. by a Living.Yeast Bio.enso. via an Epito.e-Selective Pro.ease

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Bio.esig. Research 2023年第1期5卷 1-11页

作者： Tea Crnko.ić Benjamin J.Bo.o. Mead E.lockwood Virg.nia W.Co.nish Department o. Chemistry Columbia UniversityNew YorkNY 10027USA. Department o. Bio.o.ical Sciences Columbia UniversityNew YorkNY 10027USA. Scho.l o. g.neral Studies Columbia UniversityNew YorkNY 10027USA. Department o. Systems Bio.o.y Columbia UniversityNew YorkNY 10027USA. Department o. Bio.o.ical Eng.neering Massachusetts Institute of TechnologyCambridge02139 MAUSA.

We previo.sly demo.strated that we co.ld hijack the fung.l phero.o.e sig.aling.pathway to.pro.ide a living.yeast bio.enso. where peptide bio.arkers were reco.nized by g.pro.ein-co.pled recepto.s and eng.neered to.transcribe a ***,we demo.strated that the pro.ease co.ld be reintro.uced to.the bio.enso. to.pro.ide a simple mechanism fo. disting.ishing.sing.e-amino.acid chang.s in peptide lig.nds that,o.herwise,wo.ld likely be difficult to.detect using.binding.based *** characterized the do.e–respo.se curves fo. five fung.l phero.o.e g.pro.ein-co.pled recepto.s,peptides,and pro.eases—Saccharo.yces cerevisiae,Candida albicans,Schizo.accharo.yces po.be,Schizo.accharo.yces o.to.po.us,and Schizo.accharo.yces *** scanning.was carried o.t fo. the mo.t selective o. these—*** and ***—with and witho.t the *** peptide variants were disco.ered,which sho.ed diminished cleavag. by the pro.ease(CaPep2A and CaPep2A13A).Tho.e peptides were then disting.ished by utilizing.the bio.enso. strains with and witho.t the pro.ease,which selectively cleaved and altered the apparent co.centratio. o. peptide required fo. half-maximal activatio. fo. 2 peptides—CaPep and CaPep13A,respectively—by mo.e than o.e o.der o. *** results suppo.t the hypo.hesis that the living.yeast bio.enso. with a sequence-specific pro.ease can translate sing.e-amino.acid chang.s into.mo.e than o.e o.der o. mag.itude apparent shift in the co.centratio. o. peptide required fo. half-maximal *** further eng.neering.by co.putatio.al mo.eling.and directed evo.utio.,the bio.enso. co.ld likely disting.ish a wide variety o. peptide sequences beyo.d the alanine scanning.carried o.t *** the future,we envisio. inco.po.ating.pro.eases into.o.r living.yeast bio.enso. fo. use as a po.nt o. care diag.o.tic,a scalable co.municatio. lang.ag.,and o.her applicatio.s.

关键词： apparent o.herwise utilizing

HIg. RESo.UTIo. RAMAN SPECTRo.Co.Y o. SUPERLATTICE ACo.STIC PHo.o.S

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HIGH RESOLUTION RAMAN SPECTROSCOPY OF SUPERLATTICE ACOUSTIC ...

中国物理学会光散射专业委员会成立十周年暨第六届学术会议

作者： D.J.lockwood Institute fo. Micro.tructural Sciences National Research CouncilOttawaON K1A 0R6Canada

＜正＞Previo.s investig.tio.s o. fo.ded aco.stic pho.o.s in semico.ducto. superlattices have g.nerally been restricted to.medium-to.lo. reso.utio. studies using.co.ventio.al do.ble-mo.o.hro.ato. Raman spectro.co.y.A f...

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可可的种质资源

热带作物译丛 1987年第6期 32-34页

作者： g.lockwood 莫善文

可可原产于南美的丛林,被人们引种到非洲,现在非洲的可可产量占全球之半。克利奥洛类品种(即薄皮种)在2000多年以前已在中美洲栽培,尽管采种考察迄今未断,对这个作物的种质资源,仍有许多东西有待了解。本文介绍可可的起源和发展,以及为... 详细信息

可可原产于南美的丛林,被人们引种到非洲,现在非洲的可可产量占全球之半。克利奥洛类品种(即薄皮种)在2000多年以前已在中美洲栽培,尽管采种考察迄今未断,对这个作物的种质资源,仍有许多东西有待了解。本文介绍可可的起源和发展,以及为保存种质而正采取的措施。

关键词：可可属种质资源特立尼达克利奥遗传基础种植材料育种计划育种工作者国际检疫黑果腐病