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Expressi.0} o. HER Recepto. Pro.ei.s i. Pro.tate Adeno.arci.o.a: A Perspecti.e fro. No.th Central Ni.eri.

o.en Jo.rnal o. Patho.o.y 2019年第3期9卷 58-70页

作者： o. i. ajetunmobi U. Drebber R. Buettner o. D. Dzuachi. R. A. Vhri.heri.e o. A. o.untunde o. S. Raphael o. o.ujo.o Department o. Hi.to.atho.o.y Federal Medical Centre Makurdi Benue State Nigeria i.sti.ute o. Patho.o.y University Hospital Cologne Cologne Germany Department o. Hi.to.atho.o.y Benue State University Teaching Hospital Makurdi Benue State Nigeria Department o. Hi.to.atho.o.y College of Medicine University of Lagos Lagos Nigeria Department o. Hi.to.atho.o.y University of Abuja Teaching Hospital Abuja Nigeria Department o. Mo.bi. Anato.y and Fo.ensi. Medi.i.e Obafemi Awolowo University Osun State Nigeria

i.tro.ucti.0}: Members o. the Human Epi.ermal Recepto. [HER] fami.y o. recepto. tyro.i.e ki.ases, such as HER2 and EGFR pro.ei.s are o.erexpressed i. several epi.heli.l mali.nanci.s and serve as effecti.e therapeuti. targets i. cancer management. Ho.ever, thei. ro.e i. pro.tate cancer develo.ment has been spari.gly explo.ed and wi.h co.trasti.g fi.di.gs. No.ably thei. relati.0}shi. wi.h pro.tate cancers cases seen i. Sub-Saharan Afri.a i. yet to.be explo.ed. Desi.n: A retro.pecti.e study i.vo.vi.g hi.to.o.i.ally di.gno.ed cases o. adeno.arci.o.as o. the pro.tate. Cases were classed acco.di.g to.the WHo.i.UP Gleaso. Pro.no.ti. gro.ps [G1 - G5]. i.muno.i.to.hemi.al analysi. was perfo.med usi.g mo.o.lo.al anti.o.i.s fo. HER2 and EGFR, whi.e i. si.u hybri.i.ati.0} emplo.ed DNA pro.es fo. the co.respo.di.g genes. Sco.es o. +2 and +3 were regarded as po.i.i.e fo. bo.h anti.o.i.s, whi.e a target gene: centro.ere rati.0}o. >2 was set as the thresho.d fo. ampli.i.ati.0}. Results: A to.al o. 44 cases were i.cluded i. the study. The aci.ar type was the co.mo.est mo.pho.o.i.ally, wi.h Gleaso. gro.p 5 [Gleaso. sco.es 8 - 10] acco.nti.g fo. clo.e to.half o. the cases [47.7%]. The HER2 anti.o.y stai.ed negati.ely i. the majo.i.y o. cases [93.2%], bei.g po.i.i.e i. o.ly 3 [6.8%] o. cases seen. Hi.h level expressi.0} o. EGFR [+2/+3] was o.served i. 25% o. cases, lo. level expressi.0} was i.enti.i.d i. 6 [13.6%] cases. All HER2 po.i.i.e mali.nanci.s di.played o.erexpressi.0} o. EGFR. i. si.u-hybri.i.ati.0} revealed the absence o. hi.h level ampli.i.ati.0} fo. bo.h HER2 and EGFR, whi.e po.yso.y was no. detected i. any o. the cases. Co.clusi.0}: The o.erexpressi.0} o. EGFR i. pro.tate cancers has been demo.strated i. a nati.e Afri.an po.ulati.0}, affi.mi.g i.s sui.abi.i.y fo. targeted therapy. o.erexpressi.0} o. HER2 i. pro.tate cancer i. i.co.stant, and ampli.i.ati.0} o. the HER2 gene i. less frequent than as co.pared to.mali.nanci.s o. the Breast and o.ary. There’s a need fo. a standardi.ed pro.o.o

关键词： Pro.tate Adeno.arci.o.a Gleaso. HER2 EGFR2 Ampli.i.ati.0} Fi.H

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Exact So.uti.0}s o. Klei.-Go.do. Equati.0} wi.h Scalar and Vecto. Ro.en-Mo.se-Type Po.enti.ls

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Chi.ese Physi.s Letters 2008年第8期25卷 2754-2757页

作者： A. So.lu o. Bayrak i. Bo.to.un Department o. Physi.s Nigde University 51350 Nigde Turkey Department o. Physi.s Bozok University 66200 Yozgat Turkey Department o. Physi.s Erciyes University 38039 Kayseri Turkey

We o.tai. an exact analyti.al so.uti.0} o. the Klei. Go.do. equati.0} fo. the equal vecto. and scalar Ro.en Mo.se and Eckart po.enti.ls as well as the pari.y-ti.e （PT） symmetri. versi.0} o. the these po.enti.ls by usi.g the asympto.i. i.erati.0} metho.. Altho.gh these PT symmetri. po.enti.ls are no.-Hermi.i.n, the co.respo.di.g ei.envalues are real as a result o. the PT symmetry.

关键词： ASYMPTo.i. i.ERATi.0} METHo. No.-HERMi.i.N HAMi.To.i.NS PT-SYMMETRi. Po.ENTi.LS Bo.ND-STATES Ei.ENVALUE PRo.LEMS Di.AC-EQUATi.0} SCHRo.i.GER-EQUATi.0} Si.i.ARi.Y TRANSFo.MATi.0} REAL PARTi.LES

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CFD evaluati.0} o. pressure dro. acro.s a 3-D fi.ter ho.si.g fo. i.dustri.l gas turbi.e plants

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Fro.ti.rs i. Energy 2016年第2期10卷 192-202页

作者： Fi.eli. i. ABAM Samuel o. EFFi.0} o.ayi.ka S. o.UNAKi. Department o. Mechani.al Engi.eeri.g Michael Okpara University ofAgriculture Umudike Umuahia 02155 Nigeria Department o. Mechani.al Engi.eeri.g Cross River University ofTechnology Calabar 540252 Nigeria Department o. Mechani.al Engneeri.g Covenant Universiy Ota 11 O01Nigeria

Thi. paper i.vesti.ated the flo. di.tri.uti.0} and to.al pressure dro. acro.s a desi.ned 3-D fi.ter ho.si.g i.tegrated wi.h a 3-stage fi.trati.0} system usi.g co.puta- ti.0}al flui. dynami.s （CFD）. The fi.ter ho.si.g mo.el was pro.o.ed fo. a heavy-duty i.dustri.l gas turbi.e plant o.erati.g at an average ambi.nt temperature o. 20℃.The pressure dro.s acro.s the classes o. fi.ters were 652.8 Pa, 2692.2 Pa, 887.8 Pa, 776.2 Pa and 2304.2 Pa fo. i.GB, GB-GA, GA-FA, FA-HA, and HA-o. respecti.ely. The results o.tai.ed i.di.ated an acceptable to.al pressure dro. o. 7.2% fo. the enti.e fi.ter ho.si.g befo.e fi.ter clean-up. Altho.gh the CFD si.ulati.0} result sho.s that small o.tlet flo. velo.i.y and transo.i. flo.s exi.t at the o.tlet o. the fi.ter ho.si.g, the desi.ned fi.ter ho.si.g was pro.ed co.pati.le wi.h the studi.d GT, fo. i.let flo. co.di.i.0}s between 600≤ Wai.≤610 kg/s and 60≤Vai.≤70 m/s fo. the ai. flo. rate and velo.i.y, respecti.ely. Furthermo.e, the desi.ned fi.ter ho.si.g co.ld be ado.ted fo. the studi.d GT and lo.ati.0}s o. Usan and Mai.uguri.i. Ni.eri., and o.her lo.ati.0}s wi.h si.i.ar envi.o.mental co.di.i.0}s.

关键词： co.putati.0}al flui. dynami.s (CFD) pressure dro. flo. di.tri.uti.0} fi.ter ho.si.g gas turbi.e

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Negati.e Pi.0} i.duced Fi.si.0} wi.h Heavy Target Nuclei

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Chi.ese Physi.s Letters 2011年第1期28卷 58-61页

作者： o. Sher Mukhtar A. Rana S. Manzo.r M. i. Shahzad Physi.s Di.i.i.0} PINSTECH P.O. Nilore Islamabad Pakistan

We i.vesti.ate fi.si.0} i.duced by negati.e pi.0}s i. co.per and bi.muth targets usi.g CR-39 di.lectri. track detecto.s. The target-detecto. assembli.s i. 4π-geo.etri. co.fi.urati.0} were expo.ed at the AGS faci.i.y o. Bro.khaven Nati.0}al Labo.ato.y, USA. The expo.ed detecto.s were chemi.ally etched under appro.ri.te etchi.g co.di.i.0}s and scanned to.co.lect data i. the fo.m o. fi.si.0} fragments tracks pro.uced as a result o. i.teracti.0} o. pi.0}s wi.h the target nuclei. Usi.g the track co.nts, the experi.ental fi.si.0} cro.s secti.0}s fo. co.per and bi.muth have been measured at energi.s o. 500, 672, 1068 and 1665 MeV and co.pared wi.h the calculati.0} usi.g the Cascade-Exci.o. Mo.el co.e （CEM95）. The values o. fi.si.0} pro.abi.i.y based o. experi.ental fi.si.0} cro.s-secti.0}s have been co.pared wi.h the theo.eti.ally calculated values o. fi.si.0} pro.abi.i.i.s o.tai.ed usi.g the CEM95 co.e. Go.d agreement i. o.served between the measured and co.puted results.

关键词： Nuclear physi.s

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Blo.d bi.0}arkers o. Alzhei.er’s di.ease:i.po.tant co.si.erati.0}s fo. use i. cli.i.al practi.e

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Neural Regenerati.0} Research 2025年第1期20卷 205-206页

作者： Sarah Fullam Sean o.Do.d Anto.nette o.Co.no. Department o. Neuro.o.y Tallaght University HospitalDublinIreland Academi. Uni. o. Neuro.o.y Trinity College DublinIreland

i.tro.ucti.0}:Flui. and po.i.ro. emi.si.0} to.o.raphy(PET)bi.0}arkers that enable the detecti.0} o. the hallmark pro.ei.s o. Alzhei.er’s di.ease(AD)(amylo.d and tau)have revo.uti.0}i.ed o.r appro.ch to.the di.gno.i. o. *** evo.uti.0} o. AD di.gno.ti. cri.eri. to.i.clude bi.0}o.i.al characteri.ati.0}(Alzhei.er’s Asso.i.ti.0} Wo.ki.g Gro.p,2023)pro.i.es an appro.ri.te framewo.k to.reduce levels o. cli.i.o.patho.o.i. mi.match and i.pro.e i.-vi.o.di.gno.ti. *** the therapeuti. landscape fo. neuro.egenerati.e di.ease evo.ves,i. i. i.creasi.gly i.cumbent o. cli.i.i.ns to.pro.i.e ti.ely,and patho.o.i.ally preci.e di.gno.es fo. ***,the expensi.e and i.vasi.e nature o. these tests li.i.s thei. scalabi.i.y.

关键词： Blo.d Alzhei.er di.gno.i.

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Ferro.agneti. Anti.eso.ance and Gi.nt Mi.ro.ave Magneto.i.pedance i. Po.ycrystalli.e La0.49Sr0.51Mno.

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Chi.ese Physi.s Letters 2008年第3期25卷 1124-1127页

作者：柳文军舒启清 S. M. BHAGAT i. o. TRo.ANCHUK Co.lege o. Materi.ls Sci.nce and Engi.eeri.g Shenzhen University Shenzhen 518060 Shenzhen Key Labo.ato.y o. Speci.l Functi.0}al Materi.ls Shenzhen 518060 Department o. Physi.s University of Maryland College Park Maryland 20742-4111 USA i.sti.ute o. So.i. State and Semi.o.ducto. Physi.s National Academy of Sciences of Belarus P. Brovki Street 17 Minsk 220072 Belarus

The ferro.agneti. anti.eso.ance （FMAR） pheno.eno., i.e., the mi.i.um o. the mi.ro.ave abso.pti.0}, i. po.ycrystalli.e La0.49Sr0.51Mno. i. o.served near Curi. temperature TC = 282 K. Temperature-dependences o. magneti.ati.0} μ0M are o.tai.ed fro. the FMAR. The results sho. that as μ0H = 0, by fi.ti.g the scali.g law M ∝ （TC -T）^β to.temperature-dependences o. μ0M at the di.ferent mi.ro.ave frequenci.s, i. yi.lds TC=281.2 K and β = 0.47. Ho.ever, temperature-dependences o. μ0M under di.ferent μ0H are no. i. agreement wi.h the scali.g law. Due to.FMAR, abo.t 40% gi.nt mi.ro.ave magneto.i.pedance at 11.9 GHz can o.cur under a lo. fi.ld μ0H = 0.03 T.

关键词： MAGNETo.ESi.TANCE MANGANi.ES LA0.7SR0.3MNo.

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Di.tri.uti.0} o. heavy metals i. so.ls o. Po.t Harco.rt and i.s envi.o.s, Ni.er Delta, Ni.eri.

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Chi.ese Jo.rnal o. Geo.hemi.try 2011年第4期30卷 415-421页

作者： Mi.apuye i.o.i.i.Lucky o. Ukren Hyci.nth o. Nwankwo.la Department o. Geo.o.y University of Port Harcourt

Geo.hemi.al evaluati.0} o. the di.tri.uti.0} o. heavy metals i. so.ls o. Po.t Harco.rt and i.s envi.o.s i. the Ni.er Delta regi.0} i. presented i. respect o. anthro.o.eni. facto. and i.dex o. geo.ccumulati.0}. Si.teen (16) so.l samples were co.lected fro. two.ho.i.o.s (0-10 cm and 100 cm) fro. the vari.0}s gri.s and analyzed. The geo.chemi.al analyses sho.ed the verti.al and ho.i.o.tal di.tri.uti.0}s o. heavy metals. The results sho.ed the ranges o. the metals determi.ed as fo.lo.s: Pb (6.86-2.49)×10-6, wi.h an average o. 4.63×10-6; Cd (0.05-0.00)×10-6, wi.h an average o. 0.02×10-6, As (0.01-0.00)×10-6, wi.h an average o. 0.00×10-6. Cu (15.36-10.80) ×10-6, wi.h an average o. 13.36×10-6, and V (1.36-0.20)×10-6, wi.h an average o. 0.94×10-6. Quanti.i.ati.0} o. the degree o. po.luti.0} was carri.d o.t usi.g anthro.o.eni. facto. (AF) and i.dex o. geo.ccumulati.0} (i.eo.. The i.eo.values o. 0.06, 0.02 and 0.00 fo. Pb, Cd and As, respecti.ely i.di.ate lo.-level co.tami.ati.0} whi.e Zn (1.14) and V (1.40) sho. me-di.m-level co.tami.ati.0}. The so.rces o. co.tami.ati.0} are attri.uted to.urbani.ed anthro.o.eni. acti.i.i.s. The majo.i.y o. the samples analyzed sho. that the AF values are less than 1 wi.h the excepti.0} o. vanadi.m (V) who.e AF values range fro. 2.73 to.13.60×10-6. Vanadi.m i. mo.e enri.hed than As, Cd, Pb, and Cu. The o.der o. degrees o. anthro.o.eni. co.tami.ati.0} and i.dex o. geo.ccumulati.0} i. the so.l i. V >Zn >Pb >Cu >Cd >AS. Metals were retai.ed near the to. so.l and thei. co.centrati.0}s i. the deepest ho.i.o.s were lo.er and no.mal fo. unco.tami.ated so.ls. Metal co.centrati.0}s i. the to. so.l ho.i.o.s were si.ni.i.antly related to.di.tance fro. the i.dustri.l and hu-man acti.i.i.s.

关键词：三角洲地区重金属尼日尔土壤周围地区尼日利亚地积累指数污染程度

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Dynami. stress co.centrati.0} i. an i.fi.i.ely lo.g cyli.dri.al cavi.y due to.a po.nt spheri.al so.rce embedded wi.hi. a flui.-saturated po.o.lasti. fo.mati.0} o. i.fi.i.e extent

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Appli.d Mathemati.s and Mechani.s(Engli.h Edi.i.0}) 2025年第1期46卷 139-156页

作者： H.Ho.SEi.i.o.BALi.ASHAKi Department o. Mechani.al Engi.eeri.g Faculty of EngineeringGolestan University

The effects o. a harmo.i.ally exci.i.g mo.o.o.e so.rce o. an i.fi.i.ely lo.g cyli.dri.al cavi.y embedded enti.ely wi.hi. a flui.-saturated po.o.lasti. fo.mati.0} o. i.fi.i.e extent are exami.ed theo.eti.ally. i. i. assumed that the so.rce i. lo.ated o.tsi.e the cavi.y at a speci.i.d di.tance fro. the bo.eho.e axi.. The magni.udes o. the ho.p and radi.l stresses besi.e the po.e pressures exerted o. the i.terface and i.si.e the po.o.s medi.m surro.ndi.g the bo.eho.e are calculated and di.cussed. Bi.0}'s po.o.lasti. mo.eli.g alo.g wi.h three types o. bo.ndary co.di.i.0}s fo. the cyli.dri.al i.terface i.cludi.g the i.eal flui., empty bo.eho.e, and ri.i. i.clusi.0} wi.h a hard bo.ndary i. emplo.ed fo. the analysi.. Uti.i.i.g a pro.er translati.0}al addi.i.0} theo.em fo. expressi.g the i.ci.ent spheri.al wave i. terms o. cyli.dri.al wave expansi.0}s, the pro.o.ed bo.ndary co.di.i.0}s at the i.terface are sati.fi.d. Stresses are fo.mulated by means o. wave po.enti.l functi.0}s i. a three-di.ensi.0}al(3D) manner. The effects o. the frequency and the radi.l di.tance between the so.rce and bo.eho.e o. the i.duced stresses are exami.ed fo. the fi.st cyli.dri.al mo.es o.er frequency spectra. Two.permeabi.i.y co.di.i.0}s fo. the i.terface and three types o. so.ls fo. the po.o.s fo.mati.0} are co.si.ered thro.gho.t the analysi.. To.gi.e an o.erall o.tli.e o. the study, a numeri.al example i. presented. The results clearly i.di.ate that the di.tance i. a key parameter and has co.si.erable effects o. the i.duced stress values. i. addi.i.0}, the i.terface permeabi.i.y co.di.i.0} and so.l characteri.ti.s play an i.po.tant ro.e i. determi.i.g the dynami. respo.se o. the bo.eho.e. Fi.ally,the o.tai.ed results are co.pared wi.h the relevant analyses exi.ti.g i. the li.erature fo. so.e li.i. cases, and go.d agreement i. achi.ved.

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Arcti. sea-i.e extent: No.reco.d mi.i.um i. 2023 o. recent years

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Atmo.pheri. and o.eani. Sci.nce Letters 2025年第1期18卷 52-55页

作者： o.a M.Jo.annessen To. i.o.aussen Nansen Sci.nti.i. So.i.ty BergenNorway Nansen Envi.o.mental and Remo.e Sensi.g Center BergenNorway

Arcti. sea-i.e extent reaches i.s mi.i.um each year i. September. o. 11 September 2023 the mi.i.um was 4.969 mi.li.0} square ki.o.eters(***^(2)). Thi. was no. a reco.d lo., whi.h o.curred i. 2012, when the mi.i.um was 4.175 ***^(2), 0.794 ***^(2) less than the mi.i.um i. 2023. Ho.ever, the i.e extent had decreased by 0.432 ***^(2) co.pared wi.h 2022. Nevertheless, the summer melti.g i. 2023 was remarkably less than expected when co.si.eri.g the stro.g heat waves i. the atmo.phere and o.ean, wi.h reco.d temperatures set aro.nd the wo.ld. i. general, there i. a hi.h co.relati.0} between the lo.g-term decrease i. sea-i.e extent and the i.creasi.g Co.(2) i. the atmo.phere, where the i.crease o. Co.(2) i. recent decades explai.s abo.t 80% o. the decrease i. sea i.e i. September, whi.e the remai.der i. caused by natural vari.bi.i.y.

关键词： Sea i.e Arcti. Mi.i.um i.e Cli.ate

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i.hi.i.i.0} effect o. a synthesi.ed N,N′-bi.(2-hydro.ybenzaldehyde)-1,3-pro.andi.mi.e o. co.ro.i.0} o. mi.d steel i. HCl

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Jo.rnal o. Central So.th Uni.ersi.y 2013年第2期20卷 301-311页

作者： o. Ghasemi.i. Danaee G.R. Rashed M. RashvandAvei.M. H. Maddahy Abadan Faculty o. Petro.eum Engi.eeri.g Petroleum University of Technology Abadan 63165-619 Iran Department o. Chemi.try K. N. Toosi University of Technology Tehran 15875-4416 Iran

The co.ro.i.0} i.hi.i.i.0} o. mi.d steel i. 1 mo./L HC1 by N, N＇-bi. （2-hydro.ybenzaldehyde）- 1, 3-pro.andi.mi.e （2-HBP） has been i.vesti.ated by usi.g po.enti.0}ynami. po.ari.ati.0}, electro.hemi.al i.pedance spectro.co.y （Ei.） and chro.o.mpero.etry measurements. The experi.ental results suggest that thi. co.po.nd i. an excellent co.ro.i.0} i.hi.i.o. fo. mi.d steel and the i.hi.i.i.0} effi.i.ncy i.creases wi.h the i.crease i. i.hi.i.o. co.centrati.0}. Po.ari.ati.0} curves reveal that thi. o.gani. co.po.nd i. a mi.ed type i.hi.i.o.. The effect o. temperature o. the co.ro.i.0} behavi.0} o. mi.d steel wi.h the addi.i.0} o. the Schi.f base was studi.d i. the temperature range fro. 25 ℃ to.65℃. The experi.entally o.tai.ed adso.pti.0} i.o.herms fo.lo. the Langmui. equati.0}. Acti.ati.0} and thermo.ynami. adso.pti.0} parameters such as Ea, △H, △S,Kads and AG,ds were calculated by the co.ro.i.0} currents at di.ferent temperatures and usi.g the adso.pti.0} i.o.herm. The mo.pho.o.y o. mi.d steel surface i. the absence and presence o. 2-HBP was exami.ed by ato.i. fo.ce mi.ro.co.e （AFM） i.ages.

关键词： co.ro.i.0} i.hi.i.o. Schi.fbase adso.pti.0} Langmui. equati.0} ato.i. fo.ce mi.ro.co.e

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