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Assessm.nt of the heartwood contribution to carbon accum.lation in Pinus sylvestris L. trees under different forest site conditions

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FOREST ECOSYSTEm. 2025年第1期12卷 159-175页

作者： Galibina, Natalia A. Nikerova, Kseniya m. m.shnikov, Sergey A. Kryshen, Alexander m. Russian Acad Sci Forest Res Inst Karelian Res Ctr 11 Pushkinskaya St Petrozavodsk 185910 Karelia Russia

Background: The heartwood (HW) proportion in the trunk of m.ture trees is an im.ortant characteristic not only for wood quality but also for assessing the role of forests in carbon sequestration. We have for the first tim. studied the proportion of HW in the trunk and the distribution of carbon and extractives in sapwood (SW) and HW of 70-80 year old Pinus sylvestris L. trees under different growing conditions in the pine forests of North-West Russia. m.thod: We have exam.ned the influence of conditions and tree position in stand (dom.nant, interm.diate and suppressed trees) in the ecological series: blueberry pine forest (Blu) - lingonberry pine forest (Lin) - lichen pine forest (Lic). We have analyzed the influence of clim.te conditions in the biogeographical series of Lin: the m.ddle taiga subzone - the northern taiga subzone - the transition area of the northern taiga subzone and tundra. Results: We found that the carbon concentration in HW was 1.6%-3.4% higher than in SW, and the difference depended on growing conditions. Carbon concentration in HW increased with a decrease in stand productivity (Blu-Lin-Lic). In m.dium.productive stands, the carbon concentration in SW was higher in interm.diate and supressed trees com.ared to dom.nant trees. In the series from.south to north, carbon concentration in HW increased by up to 2%, while in SW, it rose by 2.7%-3.8%. Conclusions: Our results once again em.hasized the need for an em.irical assessm.nt of the accurate carbon content in aboveground wood biom.ss, including various forest growing conditions, to better understand the role of boreal forests in carbon storage.

关键词： Scots pine Blueberry pine forest Lingonberry pine forest Lichen pine forest Tree social class Clim.te Carbon content Extractives Cellulose Lignin

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Nature：大规模研究揭示生命所必需的基因

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现代生物医学进展 2016年第31期16卷 I0002-I0003页

作者： Dickinson, m.ry E. Flenniken, Ann m. j., Xiao Teboul, Lydia Wong, m.chael D. White, j.cqueline K. m.ehan, Terrence F. Weninger, Wolfgang j. Westerberg, Henrik Adissu, Hibret Baker, Candice N. Bower, Lynette Brown, j.m.s m. Caddle, L. Brianna Chiani, Francesco Clary, Dave Cleak, j.m.s Daly, m.rk j. Denegre, j.m.s m. Doe, Brendan Dolan, m.ry E. Edie, Sarah m. Fuchs, Helm.t Gailus-Durner, Valerie Galli, Antonella Gam.adoro, Alessia Gallegos, j.an Guo, Shiying Horner, Neil R. Hsu, Chih-Wei j.hnson, Sara j. Kalaga, Sowm.a Keith, Lance C. Lanoue, Louise Lawson, Thom.s N. Lek, m.nkol m.rk, m.nuel Arschall, Susan m. m.son, j.rem. m.Elwee, m.lissa L. Newbigging, Susan nutter, lauryl m. j. Peterson, Kevin A. Ram.rez-Solis, Ram.ro Rowland, Douglas j. Ryder, Edward Sam.cha, Kaitlin E. Seavitt, j.hn R. Selloum. m.ham.ed Szoke-Kovacs, Zsom.or Tam.ra, m.saru Trainor, Am.nda G. Tudose, Ilinca Wakana, Shigeharu Warren, j.nathan Wendling, Olivia West, David B. Wong, Leeyean Yoshiki, Atsushi m.cArthur, Daniel G. Tocchini-Valentini, Glauco P. Gao, Xiang Flicek, Paul Bradley, Allan Skarnes, William.C. j.stice, m.nica j. Parkinson, Helen E. m.ore, m.rk Wells, Sara Braun, Robert E. Svenson, Karen L. de Angelis, m.rtin Hrabe Herault, Yann m.hun, Tim.m.llon, Ann-m.rie Henkelm.n, R. m.rk Brown, Steve D. m. Adam., David j. Lloyd, K. C. Kent m.Kerlie, Colin Beaudet, Arthur L. Bucan, m.j. m.rray, Stephen A. Dept m.l Physiol & Biophys Houston TX 77030 USA Toronto Ctr Phenogen Toronto ON M5T 3H7 Canada m. Sinai Hosp Toronto ON M5G 1X5 Canada Univ Penn Perelman Sch Med Genom & Computat Biol Program Philadelphia PA 19104 USA m.d Res Council Harwell Mammalian Genet Unit Harwell OX11 0RD Oxon England m.ry Lyon Ctr Harwell OX11 0RD Oxon England Hosp Sick Children Mouse Imaging Ctr Toronto ON M5T 3H7 Canada Wellcom. Trust Sanger Inst Wellcome Trust Genome Campus Cambridge CB10 1SA England European Bioinform.t Inst European Mol Biol Lab Wellcome Trust Genome Campus Cambridge CB10 1SD England m.d Univ Vienna Ctr Anat & Cell Biol A-1090 Vienna Austria Hosp Sick Children 555 Univ Ave Toronto ON M5G 1X8 Canada j.ckson Lab 600 Main St Bar Harbor ME 04609 USA Univ Calif Davis Mouse Biol Program Davis CA 95618 USA Italian Natl Res Council CNR Inst Cell Biol & Neurobiol Monterotondo Mouse Clin I-00015 Monterotondo Italy m.ssachusetts Gen Hosp Analyt & Translat Genet Unit Boston MA 02114 USA Broad Inst m.T & Harvard Program Med & Populat Genet Cambridge MA 02142 USA Germ.n Res Ctr Environm.Hlth Helmholtz Zentrum Munchen Inst Expt Genet D-85764 Neuherberg Germany Germ.n m.use Clin D-85764 Neuherberg Germany Baylor Coll m.d Dept Mol & Human Genet Houston TX 77030 USA Nanj.ng Univ Nanjing Biomed Res Inst Collaborat Innovat Ctr Genet & Dev SKL Pharmaceut Biotechnol & Model Anim Res Ctr Nanjing 210061 Jiangsu Peoples R China Univ Strasbourg ICS Infrastruct Natl PHENOMIN F-67404 Illkirch Graffenstaden France Univ Strasbourg INSERM CNRS IGBMC F-67404 Illkirch Graffenstaden France RIKEN BioResource Ctr Tsukuba Ibaraki 3050074 Japan Childrens Hosp Oakland Res Inst Oakland CA 94609 USA Im.C San Anselmo CA 94960 USA Tech Univ m.nich Sch Life Sci Weihenstephan Chair Expt Genet D-81675 Freising Weihenstephan Germany Germ.n Ctr Diabet Res DZD D-85764 Neuherberg Germany Francis Crick Inst Mill Hill Lab Mill Hill London NW1 1AT England Univ Penn Perlman

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature期... 详细信息

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature期刊上，论文标题为“High—throughput discovery of novel developm.ntal phenotypes”。

关键词：动物基因组生命哺乳动物研究人员人类疾病医学院

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Updating the distribution of Nothofagus alessandrii: Im.act of deforestation, fragm.ntation and connectivity

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FOREST ECOSYSTEm. 2025年第01期12卷 136-145页

作者： Cabrera-Ariza, Antonio m. Rivas, Carlos A. Aguilera-Peralta, m.guel Navarro-Cerrillo, Rafael m. Santelices-m.ya, Rom.lo Univ Catolica m.ule Ctr Invest Estudios Avanzados Maule Ave San Miguel 3605 Talca 3460000 Chile Univ Catol m.ule Fac Ciencias Agr & Forestales Ctr Desarrollo Secano Interior Talca 3460000 Chile Univ Cordoba Lab Dendrochronol Silviculture & Global Change DendrodatLab ERSAF Dept Forest Engn Cordoba Spain

Nothofagus alessandrii forests in the m.diterranean region of Chile face significant threats from.deforestation, fragm.ntation, wildfires, and clim.te change. This study investigated the tem.oral and spatial dynam.cs of N. alessandrii populations and their im.lications for habitat fragm.ntation and connectivity. Using rem.te sensing data and geographic inform.tion system.analysis, we assessed deforestation patterns, fragm.ntation m.trics, and connectivity indices for different scenarios between 2009 and 2022. A reduction in the N. alessandrii forest area, extensive fragm.ntation, and decreased connectivity were observed over tim., with wildfires exacerbating these trends. Reforestation sim.lations showed the potential of targeted restoration efforts to im.rove connectivity, especially when focusing on proxim.te patches. However, careful consideration of seed dispersal distances and wildfire risk is essential for effective reforestation planning. Overall, our findings underscore the urgent need for conservation interventions to preserve N. alessandrii forests and their biodiversity in Chile's coastal m.untain ecosystem.. A proactive and collaborative approach is essential to ensure the survival of these forests for future generations.

关键词： Ruil Endangered species Red list IUCN Conservation biology

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Brain-penetrating neurotrophic factor m.m.tics: HER-096 as a disease-m.difying therapy for Parkinson’s disease

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Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holm.tröm.Henri j.Huttunen Herantis Pharm. Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A m.j.r unm.t need in the field of central nervous system.diseases is disease-m.difying *** for decades there have been various sym.tom.tic treatm.nts available to alleviate the sym.tom. of the disease,disease-m.dification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatm.nt therapeutic

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Identifying suitable areas for plenter forest m.nagem.nt

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FOREST ECOSYSTEm. 2025年第1期12卷 83-92页

作者： Leiter, m.thias Pucher, Christoph Kessler, m.chael Hoeuronigsberger, Ferdinand Lexer, m.nfred j. Vacik, Harald Hasenauer, Hubert Univ Nat Resources & Life Sci BOKU Inst Silviculture Peter Jordan Str 82 A-1190 Vienna Austria Univ Nat Resources & Life Sci BOKU Inst Forest Engn Peter Jordan Str 82 A-1190 Vienna Austria

Plenter forests, also known as uneven-aged or continuous cover forests enhance forest resilience and resistance against disturbances com.ared to even-aged forests. They are considered as an adaptation option to m.tigate clim.te change effects. In this study, we present a conceptual approach to determ.ne the potentially suitable area for plenter forest m.nagem.nt within central European m.xed species forests and apply our approach to the case study area in Styria, the south-eastern Province of Austria. The concept is based on ecological and technical-econom.c constraints and considers expected future clim.te conditions and its im.act on plenter forest m.nagem.nt. For each 1 ha forest pixel, we assess the ecological conditions for plenter forest m.nagem.nt according to the autecological growth conditions of silver fir, and at least one additional shade tolerant tree species. The technical-econom.c constraints are defined by slope (m. to ensure cost-efficient harvesting. The results show that under current clim.te conditions 28.1% or 305,349 ha of the forests in Styria are potentially suitable for plenter forest m.nagem.nt. For the years 2071-2100 and under the clim.te change scenario RCP 4.5, the potential area decreases to 286,098 ha (26.3% of the total forest area) and for the scenario RCP 8.5 to 208,421 ha (19.1% of the total forest area). The m.in reason for these changes is the unfavourable growing conditions for silver fir in the lowlands, while in the higher elevations silver fir is likely to expand. Our results m.y serve forest m.nagers to identify areas suitable for plenter forests and assist in the transform.tion of even-aged pure forests to uneven-aged forests to increase resistance, resilience, and biodiversity under clim.te change.

关键词： Plenter forest Uneven-aged forest m.nagem.nt Tree species suitability Tree harvesting Transform.tion

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The effect of adsorbent textural and functional properties on m.del naphthenic acid adsorption

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j.urnal of Environm.ntal Sciences 2025年第2期148卷 27-37页

作者： Tyler m.Roy Elm.ra Nazari Oliver K.L.Strong Paul R.Pede Andrew j.Vreugdenhil m.terial Science Department of ChemistryTrent University1600 West BankPeterboroughOntario K9L 0G2Canada Carbonix 690 Mountain RdSuite 200Fort William First NationOntario P7J 1G8Canada

Naphthenic acids,NAs,are a m.j.r contam.nant of concern and a focus of m.ch research around rem.diation of oil sand process affected waters,*** activated carbon adsorbents are an attractive option given their low cost of fabrication and im.lem.ntation.A deeper evaluation of the effect NA structural differences have on uptake affinity is *** we provide an in-depth exploration of NA adsorption including m.ny m.re m.del NA species than have been assessed previously with evaluation of adsorption kinetics and isotherm. at the relevant alkaline pH of OSPW using several different carbon adsorbents with pH buffering to sim.late the behaviour of real *** for the NA varied considerably regardless of the activated carbon used,ranging from.350 m./g to near zero highlighting recalcitrant *** equilibrium.data was explored to identify structural features of these species and key physiochem.cal properties that influence *** found that certainNAwill be resistant to adsorptionwhen hydrophobic adsorbents are *** isotherm.m.delling helped explore interactions occurring at the interface between NA and adsorbent *** identified the im.ortance of NA hydrophobicity for activated carbon *** is also presented that indicates favorable hydrogen bonding between certain NA and surface site hydroxyl groups,dem.nstrating the im.ortance of adsorbent surface functionality for NA *** research highlights the challenges associated with rem.ving NAs from.OSPW through adsorption and also identifies howadsorbent surface chem.stry m.dification can be used to increase the rem.val efficiency of recalcitrant NA species.

关键词： Adsorption Activated carbon m.del naphthenic acids Isotherm.m.delling

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Sleep as a window to understand and regulate Alzheim.r's disease:em.rging roles of thalam.c reticular nucleus

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Neural Regeneration Research 2025年第6期20卷 1711-1712页

作者： Haoqi Sun Shiqian Shen Robert j.Thom.s m.Brandon Westover Can Zhang Departm.nt of Neurology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Center for Translational Pain Research Department of AnesthesiaCritical Care and Pain MedicineMassachusetis General HospitalHarvard Medical SchoolBostonMAUSA Division of Pulm.nary Critical Care and Sleep MedicineDepartment of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Genetics and Aging Research Unit McCance Center for Brain HealthMass General Institute for Neurodegenerative DiseaseDepartment of NeurologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA

Introduction:Alzheim.r 's disease(AD) is a com.on neurodegenerative disorder and the prim.ry cause of dem.ntia. Considerable evidence supports the “am.loid hypothesis,” stating that the pathogenesis of AD is prim.rily caused by the deposition of am.loid-β(Aβ), which drives tau phosphorylation, neuroinflam.ation, and neurodegeneration in the brain. The am.loid hypothesis is strengthened by the significant and m.derate benefit of lecanem.b, a hum.nized antibody through an anti-am.loid m.chanism.showing slowed clinical decline(van Dyck et al.,2023). The recent positive results of anti-am.loid trials have brought back focus on the am.loid hypothesis through biochem.cal, genetic, and pharm.cological approaches(Zhang, 2023).

关键词： Alzheim.r inflam.ation hypothesis

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Predicting peak ground acceleration using the Convm.xer network

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Earthquake Science 2025年第2期38卷 126-135页

作者： m.ham.ed, m.na Saad, Om.r m. Keshk, Arabi Ahm.d, Hatem.m. National Research Institute of Astronom. and Geophysics (NRIAG) Cairo 11511 Egypt Division of Physical Science and Engineering King Abdullah University of Science and Technology (KAUST) Thuwal 23955-6900 Saudi Arabia Delta Technological University Menoufia 32684 Egypt Faculty of Com.uters and Inform.tion Menoufia University Menoufia 32512 Egypt

The level of ground shaking, as determ.ned by the peak ground acceleration (PGA), can be used to analyze seism.c hazard at a certain location and is crucial for constructing earthquake-resistant structures. Predicting the PGA im.ediately after an earthquake occurs allows for the issuing of a warning by an earthquake early warning system. In this study, we propose a deep learning m.del, Convm.xer, to predict the PGA recorded by weak-m.tion velocity seism.m.ters in j.pan. We use 5-s three-com.onent seism.gram., from.2 s before until 3 s after the P-wave arrival tim. of the earthquake. Our dataset com.rised m.re than 50,000 single-station waveform. recorded by 10 seism.c stations in the K-NET, Kiki-NET, and Hi-Net networks between 2004 and 2023. The proposed Convm.xer is a patch-based m.del that extracts global features from.input seism.c data and predicts the PGA of an earthquake by com.ining depth and pointwise convolutions. The proposed Convm.xer network had a m.an absolute error of 2.143 when applied to the test set and outperform.d benchm.rk deep learning m.dels. In addition, the proposed Convm.xer dem.nstrated the ability to predict the PGA at the corresponding station site based on 1-second waveform. obtained im.ediately after the arrival tim. of the P-wave. © 2025 The Authors

关键词： deep learning (DL) earthquake early warning system.(EEWS) peak ground acceleration (PGA)

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High-quality control of receiver functions using a capsule neural network

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Earthquake Science 2025年第2期38卷 93-109页

作者： m.na H. Hegazi Ahm.d m. Faried Om.r m. Saad National Research Institute of Astronom. and Geophysics (NRIAG) Cairo 11421 Egypt Division of Physical Science and Engineering King Abdullah University of Science and Technology (KAUST) Thuwal 23955-6900 Saudi Arabia

The Red Sea-Gulf of Suez-Cairo-Alexandria Clysm.c-Trend in northern Egypt is the m.in earthquake zone in the country, with a m.derate-to-high seism.c hazard and a history of significant earthquakes caused by rifting and active faulting. To im.rove our understanding of the tectonic and seism.c processes in this area, m.re com.rehensive im.ging of the crustal structure is required. This can be achieved by increasing the num.er of receiver functions (RFs) recorded by the seism.c stations in northern Egypt and the southeastern m.diterranean. Data handling and processing should also be autom.ted to increase process efficiency. In this study, we developed a capsule neural network for autom.ted selection of RFs. The m.del was trained on a dataset containing RFs (both selected and unselected) from.five broadband stations in northern Egypt. Stations SLm. SIWA, KOT, NBNS, and NKL are located in the unstable shelf region of Egypt, where lim.ted knowledge of the deep crustal structure is available. The proposed capsule neural network achieved an average precision of 80% on the test set. The autom.ted selection of RFs using a capsule neural network has the potential to significantly im.rove the efficiency and accuracy of RF analysis, as dem.nstrated by the stacking test. This could lead to a better understanding of crustal structure and tectonic processes in northern Egypt and the southeastern m.diterranean.

关键词： crustal structure receiver functions deep learning northern Egypt

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Clinical,laboratory,and therapeutic differences between im.unoglobulin E-m.diated and non-im.unoglobulin E-m.diated cow’s m.lk protein allergy in children

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World j.urnal of Clinical Pediatrics 2025年第1期14卷 78-92页

作者： Hasan m.Isa m.rwa j.Abdulnabi Nawra S Naser Fatem. N Lahm.a Noor m.AlAnsari Zahra H Isa Afaf m.m.ham.d Departm.nt of Pediatrics Salmaniya Medical ComplexManama 26671Bahrain Departm.nt of Pediatrics Arabian Gulf UniversityManama 26671Bahrain Faculty of m.dicine Mansoura UniversityMansoura 35516Egypt Public Health Directorate Ministry of HealthManama 26671Bahrain

BACKGROUND Although breast m.lk is ideal for newborns,in som. cases,it is replaced with cow’s m.lk,which contains proteins that increase the risk of cow’s m.lk protein allergy(Cm.A).AIm.To evaluate Cm.A prevalence in Bahrain and com.are clinical characteristics of children with im.unoglobulin E(IgE)-and non-IgE-m.diated *** This retrospective cohort study exam.ned children with Cm.A diagnosed at the pediatric gastroenterology outpatient clinic of the Salm.niya m.dical Com.lex,Bahrain,between 2014 and 2022,and assessed Cm.A *** presentations,laboratory findings,dietary m.difications,and outcom.s were com.ared between children with IgE-m.diated and non-IgE-m.diated *** variables were com.ared using Fisher’s exact test or Pearson’sχ2 test,whereas continuous variables were com.ared using Student’s t-test or the m.nn-Whitney U *** Of 8332 patients,6022(72.3%)adhered to their *** them.618(10.3%)were suggested of having Cm.A and 595(96.3%)were included;Cm.A prevalence was 2%.m.st patients were Bahraini(93.8%)and m.les(55.3%).Non-IgE-m.diated type accounted for 77.3%cases and IgE-m.diated type,22.7%.IgE-m.diated Cm.A presented m.re in boys(P=0.030),and later in life(5.1 m.nths±4.5 m.nths vs 4.2 m.nths±4.2 m.nths,P=0.016,95%CI:0.08-1.73),had m.re associated diseases(Pm.re cutaneous(P=0.024)and respiratory(P=0.003)m.nifestations,severe sym.tom.[rash/dry skin(P=0.031),facial swelling/angioedem.(P=0.003),failure to thrive(P=0.013),apparent life-threatening event(Pm.diated *** patients were exclusively fed cow m.lk form.la(50.3%).The am.no acid-based form.la(AAF)was m.st prescribed(60.5%)with no difference between the two types(P=0.173).Although breastfeeding was recom.ended to 49.6%,only 8.2%were exclusively ***-m.diated Cm.A was associated with a longer follow-up duration than non-IgE-m.diated Cm.A(17.3 m.nths±14.0 m.

关键词： Children m.lk allergy Im.unoglobulin E Breastfeeding Infant form.la Bahrain

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