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Structural and Functional Annotation of Hypothetical Protein of Fusobacterium nucleatum Strain MJR7757B: An in Silico Approach

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Computational Molecular Bioscience 2024年第1期14卷 17-33页

作者： Md. Isrfil Hossen Fouzia Mostafa nusrat jahan Jannatul Ferdaus Amgad Albahi Sayed Mashequl Bari College of Food Science and Technology Huazhong Agricultural University Wuhan China Department of Crop Science and Technology Rajshahi University Rajshahi Bangladesh Abdul Malek Ukil Medical College Noakhali Bangladesh Department of Medicine IBN Sina Medical College Dhaka Bangladesh National Food Research Centre Khartoum Sudan Department of Aquatic Animal Health Management Sher-e-Bangla Agricultural University Dhaka Bangladesh

Fusobacterium nucleatum is an anaerobic, commensal, gram-negative oral bacterium that is carcinogenic and causes a wide range of human diseases. The present study focused on the analysis of the hypothetical protein, HMPREF3221_01179, derived from F. nucleatum strain MJR7757B, employing various computational methods to anticipate both its structure and functional characteristics. NCBI conserved domain analysis, NCBI BLASTp and MEGA Phylogenetic tree study characterize the target protein as an outer membrane efflux protein (ToIC family) which facilitate the bacterial transmembrane transport. With a molecular weight of 52120.02 Da, an isoelectric point (pI) of 8.33, and an instability index of 29.47, the protein is anticipated to exhibit good solubility in the extracellular space and crucial stability for pharmaceutical applications. The protein’s structure meets quality standards during the construction and refinement of its 3D model. The efflux inhibitor Arginine beta-naphthylamide exhibits a significant binding affinity (-7.1 kcal/mol) to the binding site of the target protein. The in-silico analysis improves the understanding of the protein and facilitates future investigations into therapeutic medication.

关键词： Fusobacterium nucleatum In Silico Bacteria Hypothetical Protein Molecular Docking

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Clinico-Epidemiological Profile and Diagnostic Procedures of Tuberculosis in Children: A Retrospective Study from OPD of Tertiary Care Center in Bangladesh

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Journal of Tuberculosis Research 2023年第1期11卷 1-11页

作者： Mujammel Haque Sutopa Halder Supti nusrat jahan Elora Sharmin Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh

Background: Childhood Tuberculosis (TB) is an important cause of mortality and morbidity, which causes a significant TB burden in developing countries. Objectives: The aim of this study was to describe clinical profile and diagnostic procedures used in Outpatient Department (OPD) of a tertiary care hospital. Methods: It was a retrospective study conducted in OPD of Paediatrics Department, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh. Age range of studied populations, 3 months to 18 years who presented with clinical features of TB and were later diagnosed with tuberculosis according to national guidelines for the management of tuberculosis in children, 2021 were enrolled in this study. A total of 108 diagnosed cases of Tuberculosis between August 2021 and July 2022 were enrolled in this study. Data were collected from OPD records and transferred into MS excel sheet for data processing & analysis. Results: Among 834 suspected patients, 108 patients aged 3 months to 18 years were diagnosed with tuberculosis. The highest number of cases 47 (43.51%) were found in 11 - 18 years age group. Gender distribution of the patient showed 58 (53.70%) were male and 50 (46.29%) were female. Among 108 TB cases, 44 (40.74%) were pulmonary TB and 64 (59.25%) were extrapulmonary TB. Among 64 extrapulmonary TB cases 38 (59.37%) cases were diagnosed as TB lymphadenitis. Fever 83 (76.85%), weight loss 62 (57.4%), cough 50 (46.29%), lump in neck and axilla 38 (35.18%) were found in most of the cases. A positive Mantoux test was found in 68 (62.96%) patients. Chest X-ray findings showed patchy opacity and consolidation in 46 (42.59%) cases. Suggestive FNAC from lymph node was observed among 35 (32.4%) cases. For bacteriological confirmation sputum gene Xpert and stool Xpert ultra were positive among 10 (9.25%) and 23 (21.29%) cases. Conclusion: In this study, Extrapulmonary TB (EPTB) cases were more than Pulmonary TB (PTB) in children. Diagnosis of tuberculosis was

关键词： Tuberculosis Pulmonary Extrapulmonary Mantoux

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Impact of Numerous Beds Operating Conditions for Enhancing the Performance of a Solar Heat-Supported Adsorption Chiller

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Journal of Applied Mathematics and Physics 2023年第11期11卷 3651-3665页

作者： nusrat jahan M. Abdul Hakim Khan K. M. Ariful Kabir Department of Science and Humanity Bangladesh Army International University of Science and Technology Comilla Bangladesh Department of Mathematics Bangladesh University of Engineering and Technology Dhaka Bangladesh

Thermal adsorption cooling systems have gained significant attention due to their potential for energy savings and eco-environmental impact. An analytic investigation of the heat transfer inside an adsorption chiller with various bed silica gel-water pairs is presented. A comprehensive model has been designed to accurately predict the correlation between the overall performance of the proposed chiller system and the functional and structural condition of the building. This model takes into account various factors such as temperature, humidity, and air quality to provide a detailed analysis of the system’s efficiency. At least 20 collectors consisting of a 34.4 m area (each) with a full-cycle time of 480 seconds are essential to improper run conditions. It is necessary to adjust the optimum cycle time for optimal performance. During the investigation, the base condition shows that the cooling capacity is 14 kw, 0.6 COPcycle, and 0.35 COPsolar at noon. Also, conduct a thorough investigation into the chiller’s performance under varying cooling water supply temperatures and various chilled water flow rates.

关键词： Adsorption Chillers Adsorption Cooling Multiple Adsorption Beds Solar Heat

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Evaluation of Genetic Divergence in Various Potato Genotypes Grown in Bangladesh through Different Traits Assessment

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American Journal of Plant Sciences 2023年第11期14卷 1235-1247页

作者： Md. Mukhtar Hossain Md. Abdul Kaium Md. Al Amin Tabaraka Binte Ali nusrat jahan Md Nasim Uddin Department of Crop Science and Technology Faculty of Agriculture Rajshahi University Rajshahi Bangladesh

The goal of the study was to quantify the genetic diversity of different potato varieties. Five groups were named to classify the 25 genres of potatoes as: Cluster I (Lalpakri, Diamond), Cluster II (Hagrai, Green Mountain, G.M.O., Elvera), Cluster III (Atlantic, Shepody, Raja, Fundy, Multa, Granulla, Shibilati, Japanese Red), Cluster IV (Atlas, Brondy, Yucon Gold, Monona, Petrones, Cheroki), and Cluster V (Calwhite, Prelude, Allblue, Russet, Burbank, TPS-67). The highest and lowest genotypes are found in Clusters III and I, respectively. The two groups’ maximum inter-cluster distance (the cluster’s distance between them) demonstrates the enormous diversity between Clusters II & III. Cluster III had the greatest intra-cluster distance (distance within a set), whereas Cluster V had the smallest. In most cases, the distance between gaps was more significant than the distance within the holes, showing greater genetic diversity between different groups’ genotypes. The highest, second highest, and third highest eigenvalues, accompanying the positive canonical values for Vectors I and II of three characteristics: average tuber weight in each plant, the tubers number in each plant, and the eyes number in each tuber, showed the most outstanding contribution to the complete difference between genotypes. Of the nine features, the smaller leaves number in each plant, the shorter plant height, the more minor genotypes, the fewer eyes per tube generated from Cluster I, the maximum height of the plants, the high-quality tubers in each plant, the tubers number in each plant, the fresh weight in each plant, and the leaf number in each plant from Cluster II could be chosen in the role of parents in this program for hybridization. Given the size of the genetic distance, the various characteristics that contribute to the overall difference, and the average population size, Hagrai, Green Mountain, O.M.G., Elvera Cluster II and Cluster I, Lalpakri, and Diamond genotypes can be regarded a

关键词： Genetic Divergence Potato Genotypes Different Traits Cluster Analysis Principal Component Analysis

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Impact of the Presence of the Loop at Different Location on Fabric Width and Areal Density of a Weft Knitted Structure

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Journal of Textile Science and Technology 2021年第1期7卷 55-65页

作者： Zubair Bin Sayed nusrat jahan Shabrina Kabir Department of Textile Engineering Port City International University Chittagong Bangladesh Department of Textile Engineering Ahsanullah University of Science and Technology Dhaka Bangladesh Department of Textile Machinery Design and Maintenance Bangladesh University of Textile Dhaka Bangladesh

Knitted structures are progressively built up from row after row of knitted intermeshed loops known as knitted loops. Apart from this knitted loops, tuck or miss loops may be produced by varying the timing of the intermeshing sequence of the old loop and new loops. These loops are main and prominent part of the design of the weft knitted structures. Structures having float or miss loop exhibits many noticeable characteristics. The fabrics renders better surface appearance or color pattern. Dimensional stability is significantly improved. Fabric width is reduced and areal density is also increased considerably due to the presence of float loops in the structure. Therefore, the dimensional and physical features of different knitted structures having knit-miss loops may be studied carefully to find the influence of float stitch or loop on fabric width and areal density. In this project work, such an attempt has been made to specify some specific single jersey structures, which will be ensured as an effective tool for product research and development as well as for meeting up customer’s quality requirements of high class products.

关键词： Course Per Inch Count GSM (Gram Per M2) Shrinkage Wales Per Inch Weft Knitting

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Fisheries resources of Bangladesh:Present status and future direction

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Aquaculture and Fisheries 2017年第4期2卷 145-156页

作者： Md.Mostafa Shamsuzzaman Mohammad Mahmudul Islam nusrat jahan Tania Md.Abdullah Al-Mamun Partho Protim Barman Xiangmin Xu Environmental&Resources Protection Law Ocean University of ChinaQingdao 266100China Department of Coastal and Marine Fisheries Sylhet Agricultural UniversitySylhet 3100Bangladesh Department of Fisheries Marine Fisheries OfficeChittagong 4100Bangladesh

Bangladesh is considered one of the most suitable regions for fisheries in the world,with the world's largest flooded wetland and the third largest aquatic biodiversity in Asia after China and *** paper reviews the performance of fisheries in Bangladesh using data collected from the Bangladesh Department of Fisheries,and related un-published grey *** findings within describe recent growth within Bangladeshi inland fisheries,primarily in the inland aquaculture sector(2014e2015).This increase in the aquaculture production has been made possible with the implementation of scientific and technological *** 2000 and 2016,aquaculture production increased from 712,640 and 2,060,408 metric t,a much larger quantity than wild capture production(1.023 million t)in *** has also been a recent increase in the value of fishery exports,with more than US$34.08 billion in 2010 rising to more than US$46.60 billion in ***,fisheries production is well below production targets despite the large gains seen in the aquaculture sector.

关键词： Inland fishery Aquaculture Coastal and marine Export and import Regulations Bangladesh

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Antidiabetic and antidiarrhoeal potentials of ethanolic extracts of aerial parts of Cynodon dactylon Pers

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Asian Pacific Journal of Tropical Biomedicine 2015年第8期5卷 642-645页

作者： Md.Saidur Rahman Rasheda Akter Santosh Mazumdar Faridul Islam nusrat jahan Mouri Nemai Chandra Nandi Abu Syeed Mohammad Mahmud Bangladesh Council of Scientific and Industrial Research Laboratories Chittagong

Objective: To explore the antidiabetic and the antidiarrhoeal effects of ethanolic extracts of Cynodon dactylon Pers. aerial parts(EECA) in Wistar ***: To assess the antidiabetic activity of EECA, oral glucose tolerance test(OGTT) model and alloxan induced diabetic test(AIDT) model were performed. The EECA was used at the doses of 2 g/kg, 1 g/kg and 500 mg/kg body weight in OGTT model and 1.5 g/kg was used for AIDT model. Castor oil-induced diarrhoeal model and gastrointestinal motility test with barium sulphate milk model were performed for evaluating the antidiarrhoeal effects at doses of 1 g/kg, 750 mg/kg ***: The dose 2 g/kg in OGTT and 1.5 g/kg in AIDT model blood glucose levels decreased significantly(P < 0.01) in Wistar rats that showed antidiabetic effect of EECA. After administration of EECA at the dose of 1 g/kg, the extract showed significant(P < 0.05) antidiarrhoeal activity in castor oil-induced diarrhoeal model. The results were also significant(P < 0.01) in barium sulphate milk model for the same dose by using above mentioned ***: It is concluded that EECA contains both antidiabetic and the antidiarrhoeal properties.

关键词： Cynodon dactylon Ethanolic extracts Antidiabetic Antidiarrhoeal Wistar rats

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利用图像和机器学习检测大豆作物幼苗期玉米杂苗

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智慧农业（中英文） 2020年第3期2卷 61-74页

作者： Paulo FLORES 张昭 Jithin MATHEW nusrat jahan John STENGER 北达科他州州立大学农业与生物工程系北达科他州法戈市58102美国北达科他州州立大学植物科学系北达科他州法戈市58102美国

在大豆-玉米轮作生产过程中,玉米杂苗会与大豆苗竞争水和肥料,而且很容易遮住大豆苗,影响害虫(如玉米根虫)的防控,降低大豆品质。因此,在大豆幼苗期及时检测出玉米杂苗并对其进行处理非常重要。传统的人工检测方法主观性强、效率低,传... 详细信息

在大豆-玉米轮作生产过程中,玉米杂苗会与大豆苗竞争水和肥料,而且很容易遮住大豆苗,影响害虫(如玉米根虫)的防控,降低大豆品质。因此,在大豆幼苗期及时检测出玉米杂苗并对其进行处理非常重要。传统的人工检测方法主观性强、效率低,传感器和算法的发展为自动检测玉米杂苗提供了更好的解决方案。本研究在温室环境下模仿田间条件,待玉米和大豆发芽后,连续5天用因特尔RealSense D435相机采集彩色图像,并人工裁剪幼苗图像区域,在此基础上对图像进行分割和去噪。在采集图像形状、色彩和纹理特征值后,对所采集的特征值进行权重分析,保留前10种重要的特征值导入基于特征的机器学习算法中进行模型训练和预测。预测结果表明,支持向量机模型(SVM)、神经网络(NN)和随机森林(RF)的预测精度分别为85.3%,81.5%和82.6%。将数据集导入GoogLeNet和VGG-16两种深度学习模型进行训练,预测精度分别为96.0%和96.2%。VGG-16模型在区分大豆幼苗和玉米杂苗中有较好的表现,彩色图像和VGG-16模型组成的系统可以自动检测大豆生长过程中玉米杂苗的情况,为农民提供准确的信息,帮助其进行生产决策和田间管理。

关键词：玉米-大豆轮作玉米杂苗图像处理机器学习深度学习支持向量机(SVM)

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Effect of Carboxyl Functionalized MWCNTs on the Cure Behavior of Epoxy Resin

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Open Journal of Composite Materials 2013年第2期3卷 40-47页

作者： nusrat jahan Alfred-Tcherbi Narteh Mahesh Hosur Muhammad Rahman Shaik Jeelani Materials Science and Engineering Tuskegee University Tuskegee USA.

Effects of carboxyl functionalized MWCNTs on the cure behavior of epoxy resin (EPIKOTETM resin 862 and EPICURETM curing agent W) were investigated by using differential scanning calorimeter in dynamic scan mode. Results indicated that nanotubes could initiate cure reaction at lower temperature while only 0.1 wt% samples were able to suppress the peak temperature (Tp) consistently regardless of different heating rate due to their higher reaction rate, other two batches (0.2 wt% and 0.3 wt% CNT) showed hardly any change in Tp compared to neat samples. Furthermore, addition of small amount (0.1 wt%) of CNTs significantly reduced the activation energy of the system but further addition elevated that due to their retarding effect. Also, a correlation was established between the dispersion state of CNTs in epoxy and total heat of reaction (ΔH) where lower ΔH was considered as an indication of better interfacial interaction of CNTs with matrix and hence, better dispersion. The difference in curing behavior of three different CNT percentages was discussed in terms of their steric hindrance and state of dispersion in the matrix.

关键词： Carbon Nanotubes DSC Steric Hindrance Peak Temperature Activation Energy

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An Intelligent Sensor Based System for Real Time Heart Rate Monitoring (HRM)

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Intelligent Control and Automation 2016年第2期7卷 55-62页

作者： nusrat jahan Farin S. M. A. Sharif Iftekharul Mobin Department of Computer Science and Engineering University of Liberal Arts Bangladesh (ULAB) Dhaka Bangladesh

A method and apparatus for monitoring heart rate of the heart using a wearable system is designed and implemented in this paper. A heart rate receives from heart beat signals and stores the data to a database and after a time period this method can determine an idle heart rate of the monitoring body. This idle heart rate is compared with the stored data and can determine the normal and abnormal heart rate variability. After the certain time period this system can detect the heart rate and also can send a signal to the user in time of abnormalities. Consequent estimations of heart rate variability are contrasted with this.

关键词： Heart Rate Micro-Controller Heart Rate Monitor (HRM) Wearable System Sensor Based System (SBS)

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