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Spectrophotometer with enhanced sensitivity for uric acid detection

Chinese Optics Letters 2019年第8期17卷 66-70页

作者： nurfatihah che abd rashid Nor Hafizah Ngajikin Asrul Izam Azmi rashidah Arsat Suhaila Isaak Noran Azizan Cholan Nur Ellina Azmi Faculty of Electrical Engineering Universiti Teknologi Malaysia 81310 Johor Bahru Johor Malaysia Faculty of Electrical and Electronic Engineering Universiti Tun Hussein Onn Malaysia 86400 Bt. Pahat Johor Malaysia Industrial Biotechnology Research Centre SIRIM Berhad 40200 Shah Alam Selangor Malaysia

A spectrophotometer with an LED as the light source for uric acid detection is proposed in this work. The mechanism of uric acid detection is based on energy absorbed by sodium urate, which is a chemical product of uric acid and sodium hydroxide solution. For the performance validation, comparison between the spectrophotometer with an LED and halogen lamp is carried out. Measurement results suggest that the spectrophotometer system with LED light has better sensitivity than that with halogen light. At a 460 nm wavelength,the sensitivity for the spectrophotometer with an LED is 0.0046 dL/mg, which is 73% higher than that with halogen light that records 0.0012 dL/mg. This enhanced sensitivity is attributed to the higher luminous efficacy of the LED light beam. As a result, a larger amount of flux interacts with the sample, leading to the sensitivity enhancement. The spectrophotometer with an LED is also applied for the detection of uric acid in a real human urine sample. Based on the experimental data at a 460 nm wavelength, the method manages to achieve the sensitivity of 0.0016 dL/mg, accuracy of 96.01%, limit of detection of 4.79 mg/dL, and limit of quantification of 14.52 mg/dL. These findings show that the use of LED as the input light source is promising for the spectrophotometer.

关键词： spectrophotometer mechanism show

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Effect of hand hygiene intervention on the absenteeism of pre-school children in Klang Valley,Malaysia:a quasi-experimental study

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World Journal of Pediatrics 2020年第4期16卷 416-421页

作者： Nurul Azmawati Mohamed Mohd Dzulkhairi Mohd Rani Tengku Zetty Maztura Tengku Jamaluddin Zarini Ismail Shalinawati Ramli Habibah Faroque Farisha Nur abd Samad abdul rashid Ariffien Aisyah Ar Redha che Amir FaridIlina Isahak Faculty of Medicine and Health Sciences Universiti Sains Islam MalaysiaPandan Indah55100Kuala LumpurMalaysia Faculty of Medicine and Health Sciences Universiti Putra Malaysia43400SerdangSelangorMalaysia

Background Absenteeism amongst pre-school children is often due to illnesses such as hand,foot,and mouth disease,acute gastroenteritis,cold and flu,which are easily spread amongst *** is because of weak immunity and lack of knowledge on proper hand *** quasi-experimental study assessed the efficacy of an intervention consisting of a hand hygiene education programme,along with digital tools in bringing about a change in behaviour and health conditions amongst pre-school children in Klang Valley,*** A total of 377 school children,male and female,aged 5–6 years old,participated and were assigned to either the intervention or a control *** the 2 months intervention period,children in the test group were trained on proper hand hygiene practices and techniques with the aid of the interactive android-based *** numbers of absent days of all the children were recorded for 2 months before the intervention and during the *** In the test group,there was a 25%increase in the total number of absent days from the pre-intervention period to the intervention period,a much lesser increment observed as compared to that of control group in which the increase was much higher at 89%.Results showed a significant difference(P<0·05)between the absenteeism rates for the test and control group during the intervention *** These results suggest that proper education and intervention increase hand hygiene compliance,which may help decrease school absenteeism due to illness;however,a longer study duration may be necessary to evaluate the benefit further.

关键词： Absenteeism Hand hygiene Povidone-iodine Pre-school children

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