检索结果-南通市图书馆

Inflammatory responses in esophageal mucosa before and after laparoscopic antireflux surgery

World Journal of Gastrointestinal Surgery 2024年第3期16卷 871-881页

作者： Pelin Ergun Sezgi Kipcak nur selvi gunel Eser Yildirim Sozmen Serhat Bor Department of Otolaryngology Medical College of WisconsinMilwaukeeWI 53226United States Division of Gastroenterology Ege UniversityFaculty of MedicineEge Reflux GroupIzmir 35100Turkiye Department of Medical Biology Ege UniversityFaculty of MedicineIzmir 35100Turkiye Department of Medical Biochemistry Ege UniversityFaculty of MedicineIzmir 35100Turkiye

BACKGROUND Currently,the primary treatment for gastroesophageal reflux is acid suppression with proton pump inhibitors,but they are not a cure,and some patients don’t respond well or refuse long-term ***,alternative therapies are needed to understand the disease and develop better *** anti-reflux surgery(LARS)can resolve symptoms of these patients and plays a significant role in evaluating esophageal healing after preventing harmful *** LARS improves typical gastroesophageal reflux symptoms in most patients,main-ly by reducing the exposure time to gastric contents in the ***-ration of the inflammatory response and a recovery response in the esophageal epithelium is expected following the cessation of the noxious *** To explore the role of inflammatory biomolecules in LARS and assess the time required for esophageal epithelial *** Of 22 patients with LARS(pre-and post/5.8±3.8 months after LARS)and 25 healthy controls(HCs)were *** subjects underwent 24-h multichannel intraluminal impedance-pH monitoring and upper gastrointestinal endoscopy,during which esophageal biopsy samples were collected using endoscopic *** molecules in esophageal biopsies were investigated by reverse transcription-polymerase chain reaction and multiplex-enzyme-linked immunosorbent *** Post-LARS samples showed significant increases in proinflammatory cytokines[interleukin(IL)-1β,interferon-γ,C-X-C chemokine ligand 2(CXCL2)],anti-inflammatory cytokines[CC chemokine ligand(CCL)11,CCL13,CCL17,CCL26,CCL1,CCL7,CCL8,CCL24,IL-4,IL-10],and homeostatic cytokines(CCL27,CCL20,CCL19,CCL23,C-CL25,CXCL12,migration inhibitory factor)compared to both HCs and pre-LARS ***17 and CCL21 levels were higher in pre-LARS than in HCs(P<0.05).The mRNA expression levels of AKT1,fibroblast growth factor 2,HRAS,and mitogen-activated protein kinase 4 were significantly decreased post-LARS vs pre-LARS.

关键词： Anti-reflux surgery Gastroesophageal reflux disease Cytokine Inflammatory response Esophagus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Physiochemical Composition of Fig Seed Oil from Turkey

引用

Journal of Pharmacy and Pharmacology 2019年第10期7卷 541-545页

作者： Nazan Güven Ali Gokyer Aysenur Koc Naime nur Temiz Seher selvi Beril Koparal Burcak Deniz Dedeoglu Sidika Büyükhelvacigil Oztürk Hale Feyza Büyükhelvacigil Ramazan Büyükhelvacigil Ceren Erman Zade Vital■ Natural Supplements Istanbul 34775 Turkey Zade Vital■ Natural Supplements General Menager/Zade■& Zade Global General Manager 2800 Lively Blvd Elk Grove Village IL 60007 Illinois ABD Zade Vital■ Natural Supplements Avicenna Ar&Ge Center Konya 42050 Turkey 不详

Fig (Ficus carica Linn (Moraceae)) is a deciduous tree that grows in tropical and subtropical zones [1]. Ficus carica has a broad spectrum of pharmacological activity and is widely used in traditional medicine. Research has found its use in more than 40 areas. Some of these are gastrointestinal, endocrine, respiratory, reproductive system disorders [2]. The fig seed oil contains alpha-linolenic acid (ALA), which is highly beta-sitosterol and herbal omega [3]. It can be used as a supplement in the treatment of diseases such as cardiovascular disorders, gastrointestinal disorders, and diabetes. Fig seed oil can be a good choice for skin hydration when used externally. In our study, the fig seed oil was analyzed by gas and liquid chromatography. In this study where linoleic acid (C18:2) and linolenic acid (C20:0) ratios found in fig seed oil composition were evaluated, the health benefits of two fatty acids were discussed based on the literature.

关键词： Ficus carica fig seed oil linoleic acid linolenic acid fig

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：