检索结果-南通市图书馆

Guidelines for Collection of Biological Samples for Clinical and Forensic Toxicological Analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Forensic Sciences Research 2016年第1期1卷 42-51页

作者： Ricardo Jorge Dinis-Oliveira Duarte nuno Vieira Teresa Magalhaes Department of Legal Medicine and Forensic Sciences Faculty of MedicineUniversity of PortoPortoPortugal Department of Sciences IINFACTS–Institute of Research and Advanced Training in Health Sciences and TechnologiesUniversity Institute of Health Sciences(IUCS)CESPUCRLGandraPortugal UCIBIO-REQUIMTE Laboratory of ToxicologyDepartment of Biological SciencesFaculty of PharmacyUniversity of PortoPortoPortugal Faculty of Medicine University of CoimbraPortoPortugal

This article aims to review general procedures for sampling of routinely collected as well as on alternative samples that may provide additional information regarding *** approaches may be applied whenever sample collection for clinical and forensic toxicology is required and should be considered as general guidelines that must be adapted to each specific *** is expected that this article will help toxicologists and other forensic experts to accomplish their mission,since the toxicological result is first influenced by the quality and quantity of the sample available for *** guidelines were approved by the European Council of Legal Medicine.

关键词： Forensic science forensic toxicology samples collection guidelines kits and labelling storage and preservation

Finite element model with imposed slip surfaces for earth mass safety evaluation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Central South University 2014年第9期21卷 3627-3638页

作者： nuno ARAUJO Gaspar J.MACHADO Julio B.MARTINS Hugo M.R.D.SILVA C-TAC Territory Environment and Construction Research Centre School of EngineeringUniversity of Minho Guimaraes 4800-058 Portugal Centre of Mathematics School of Sciences University of Minho Guimaraes 4800-058 Portugal

The study of earth masses requires numerical methods that provide the quantification of the safety factor without requiring detrimental assumptions. For that, equilibrium analysis can perform fast computations but require assumptions that limit its potentiality. Limit analysis does not require detrimental assumptions but are numerically demanding. This work provides a new approach that combines the advantage of both the equilibrium method and the limit analysis. The defined hybrid model allows probabilistic analysis and optimization approaches without the assumption of interslice forces. It is compared with a published case and used to perform probabilistic studies in both a homogeneous and a layered foundation. Analyses show that the shape of the density probability functions is highly relevant when computing the probability of failure, and soil elasticity hardly affects the safety of factor of the earth mass.

关键词： slope stability probabilistic methods reliability genetic algorithms safety factor

Blockchain-based refurbishment certification system for enhancing the circular economy

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Blockchain(Research and Applications) 2024年第1期5卷 85-96页

作者： Cristina Regueiro Aitor Gómez-Goiri nuno Pedrosa Christos Semertzidis Eider Iturbe Jason Mansell TECNALIA Research&Innovation Basque Research and Technology Alliance(BRTA)Parque Científico y Tecnológico de Bizkaia48160Derio BizkaiaSpain Projecto Desenvolvimento Manutenção Formação e Consultadoria Rua Fradesso da Silveira n.41B1300-609LisbonPortugal

As the global population continues to grow,the enormous stress on our environment and resources is becoming impossible to ignore.A focus on producing and consuming as cheaply as possible has created an economy in which objects are briefly used and then discarded as waste,featuring a linear lifecycle that creates an enormous amount of *** alternative to the linear economy“take-make-waste”is called the“circular economy”.Under this paradigm,materials are recycled to build new products or components that are designed and built to promote their reuse and *** assures the continuous(re-)exploitation of existing resources,reducing the extraction of new raw ***,customers often reject these reused or refurbished products under the suspicion that they do not meet the same usability,safety,or performance levels of new *** this sense,trustworthy records of historical details of refurbished products could increase consumers’confidence in products and components of the“circular economy”,prioritizing trustworthiness,reliability,and *** work presents a new certification tool based on blockchain technology to guarantee trusted,accurate,transparent,and traceable lifecycle information of products and their components and to generate trustworthy certificates to probe refurbished product historical *** tool aims to enhance refurbished product visibility by creating the basis for making the circular economy a reality in any domain.

关键词： Blockchain Traceability Lifecycle Product lifecycle management(PLM) Refurbishment Certification Circular economy

Pylephlebitis—a rare complication of a fish bone migration mimicking metastatic pancreatic cancer:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第23期9卷 6768-6774页

作者： Sofia Bezerra nuno J França Firmo Mineiro Germano Capela Cristina Duarte António Ribeiro Mendes Department of Surgery Centro Hospitalar do Médio TejoTomar 2304-909Portugal

BACKGROUND Pylephlebitis is a rare condition,poorly recognized by clinicians and with few *** this case,the clinical appearance resembled the clinical course of a pancreatic cancer and was originated by the ingestion of a fish bone,making the case more interesting and *** SUMMARY A 79-year-old female presented to the emergency department with fever,loss of appetite and *** in the right upper quadrant was *** marker were high.A computed tomography(CT)scan revealed gallstones and aspects compatible with acute *** patient was admitted to surgery ward and has her condition aggravated.A magnetic resonance revealed multifocal liver ***,a cholangiopancreatography and an endoscopic ultrasound(US)were able to diagnose the *** treatment was implemented and the patient made a complete *** In conclusion,this case report demonstrates for the first time the diagnosis of an unusual case of pylephlebitis complicated by the migration of a fish bone,mimicking metastatic pancreatic *** presentation and traditional imaging studies,such as transabdominal US and CT,remain the standard for diagnosing this condition.

关键词： Pylephlebitis Portal vein thrombosis Abdominal infection Fish bone Pancreatic cancer Case report

Sustainable living neighbourhoods:Measuring public space quality and walking environment in Lisbon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geography and Sustainability 2022年第4期3卷 289-298页

作者： Teresa Santos Filipa Ramalhete Rui Pedro Julião nuno Pires Soares Interdisciplinary Centre of Social Sciences(CICS.NOVA) Faculty of Social Sciences and Humanities(NOVA FCSH)Universidade NOVA de LisboaAv.de Berna26 CLisboa 1069-061Portugal Studies Centre on Architecture City and Territory(CEACT)Universidade Autónoma de LisboaRua Fernando Assis Pacheco207Lisboa 1350-300Portugal

Obesity and global warming are two major challengesthat affect communities’health and quality of *** good walking environments,with appropriate pedestrian infrastructure,green areas and access to commercial retail and transport hubs favour liveable,healthy,and sustainable *** Lisbon City Hall has implemented an intervention program in the public space as a strategy to improve environmental quality and mitigate the effects of climate *** program“A square in each neighbourhood”intends not only to reinforce the economic base of Lisbon,namely tourism,restaurants,commerce,and creative activities but also to promote physical activity and improve the quality of living of all *** studying the impact of the public space quality on the walking environment,Campolide,a typical Lisbon neighbourhood,Portugal,which includes one of the requalified squares,was selected.A two-step methodology based on spatial modelling is *** the first step,the public space quality was evaluated based on a set of 13 urban quality ***,intended for the street level,were collected from open data platforms and complemented with a field ***,through spatial analysis,these attributes were used to build the Pedestrian Environment Quality Indicator and the Priority Intervention *** these indicators,walking-friendly streets were mapped and the most critical sites that require priority intervention were identified to prepare for the requalification planning *** street with the highest quality in the study area according to the dimensions evaluated-connectivity,convenience,comfort,cleanliness,and conviviality-has a great offer of trees,bus stops,commercial establishments,commercial diversity,crossings,paper bins/eco points and *** the opposite side of the rank,the street with the lowest quality has no trees or green areas,transport stops,benches and tables,or commercial *** urban quality indicators constitu

关键词： Public space Walking environment Spatial modelling Urban quality indicators Geographic Information Systems

Defensive pressure affects basketball technical actions but not the time-motion variables

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2016年第3期5卷 375-380页

作者： Jaime Sampaio Roland Leser Arnold Baca Julio Calleja-Gonzalez Diogo Coutinho Bruno Goncalves nuno Leite Research Centre in Sports Sciences Health Sciences and Human Development CIDESD Creative Lab Research Community Sport Sciences Department University of Trás-Os-Montes e Alto Douro Centre for Sport Science and University Sports University of Vienna Faculty of Sport Sciences University of the Basque Country

Background: Novel player tracking technologies can change the understanding of performance determinants in team sports by allowing to accurately measuring the activity demands. The aim of this study was to identify how the defensive pressure affects the time-motion variables and the technical actions in ***: Twenty international male players(age: 16.05 ± 2.09 years, weight: 73.13 ± 8.10 kg, height: 183.10 ± 5.88 cm) played two 10 min basketball quarters, where they used a man-to-man 1/4-court defense until the 4th min(F1/4), changed to man-to-man full court(FULL) for 3 min and, from the 7th to the 10 th min returned to 1/4-court defense(S1/4). A computerized notational analysis was performed using Simi Scout and positional data were captured with the Ubisense Real Time Location System(mean sampling rate 3.74 ± 0.45 Hz per transmitter/player).Results: The time-motion variables presented similar results between defensive conditions, showing a total distance covered around 90 m/***, results suggested possible vertical jump impairments in S1/4 periods. There was more distance covered while jogging in the offensive court(38.15 ± 12.17 m/min offensive court vs. 32.94 ± 10.84 m/min defensive court, p < 0.05) and more distance covered while running in the defensive court(16.41 ± 10.27 m/min offensive court vs. 19.56 ± 10.29 m/min defensive court, p < 0.05).Conclusion: These results suggest how to improve task representativeness during specific conditioning or game-based training situations and also to help coaches' strategic decisions during the games.

关键词： Activity demands Performance analysis Performance indicators Team sports

Impact of Drug-Drug Interaction between CDK4/6 Inhibitors and Proton Pump Inhibitors on Survival Outcomes in the Treatment of Metastatic Breast Cancer—Real World Data from a Portuguese Center

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2022年第5期13卷 266-274页

作者： Joana Reis Inês Costa Mariana Costa Ana Valente Catarina almeida Marta Freitas Cláudia Caeiro Catarina Fernandes nuno Tavares Miguel Barbosa Centro Hospitalar SÃ O JOÃ O E.P.E. Porto Portugal

Introduction: Proton pump inhibitors (PPi) are widely prescribed, including in patients undergoing treatment for advanced breast cancer (ABC). Due to the pharmacokinetic characteristics of the CDK4/6 inhibitor (Ci) palbociclib a drug interaction with PPi was hypothesized. It was shown in a retrospective study that this association was an independent predictive factor for worse progression-free survival (PFS). Objective: To verify the impact of concomitant administration of PPi with Ci on overall survival (OS) and PFS. Material and Methods: This is a retrospective cohort study of patients treated with Ci for HR+HER2-ABC in the period from Feb/2017 to Aug/2020. SPSS software was used for data processing. Univariate analysis was done by the Kaplan-Meier method and log-rank test, and multivariate analysis by COX regression. P-value < 0.05 was considered significant. Results: 80 patients were included. The median age at diagnosis of ABC was 56 years (25 - 75). Treatment with Ci was 1st line for ABC in 68.8%. Choice of Ci was palbociclib in 73.8% (n = 59) and ribociclib in 26.3% (n = 21). The hormone partner was a nonsteroidal aromatase inhibitor in 45.0%, and fulvestrant in 55.0% of cases. 37.5% of patients were on PPi, and 70.0% of them were during the entire treatment (23.3% omeprazole, 73.4% pantoprazole, 3.3% others). Patients taking concomitant PPi and Ci had lower OS (OS-3 years 42.6% vs. 63.4%, p = 0.254) and PFS (PFS med 15 m. vs. 21 m., p = 0.733), although with no statistically significant difference. Discussion: In the sample, there was a numerical difference, without the statistical significance in the use of PPi in the survival of patients under Ci. This difference could be more evident with a longer follow-up and a larger sample size. This study intends to alert to the growing importance of checking for drug interactions. Polymedication, advanced age and the presence of several comorbidities are real problems in patients with ABC. Conclusion: Real-world dat

关键词： Drug Interaction Survival Impact Advanced Breast Cancer CDK4/6 Inhibitors Proton Pump Inhibitors

The Last Farewell Embrace:Spirituality,Near-Death Experiences and Other Extraordinary Events Among Nurses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Psychology Research 2019年第6期9卷 257-262页

作者： Paulo nuno Martins Centre Internationale de Recherche et d’études Transdisciplinaire (CIRET) ParisFrance Transdisciplinary Center for Studies of Consciousness (CTEC) OportoPortugal Interuniversity Center of History of Science and Technology (CIUHCT) LisbonPortugal

This recension to the book of Alejandro Parra aims to be a contribution on the various topics that the theme on the experiences in “threshold of death” addresses,namely,paranormal phenomena experienced by several people,such as the nurses,and that are impossible to be explained within the current biomedical *** this sense,the study of the concept of spirituality in health care could be an important topic to be approached in this area of research with the purpose of better understanding the patients who are in the process of “passing”,as well as expand the perspective of the current biomedical model,so as to take into consideration the human being in its various dimensions: spiritual,psychological,and physical/biological.

关键词： experiences at the threshold of death paranormal phenomena the role of spirituality

Sister Bernardette Moriau’s “Spontaneous” Healing: Some Perspectives of the Psychology of Consciousness

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Psychology Research 2021年第6期11卷 276-281页

作者： Paulo nuno Martins Centro Transdisciplinar de Estudos da Consciência(CTEC) Fernando Pessoa UniversityOportoPortugal entro Interuniversitário de História das Ciências e da Tecnologia(CIUHCT) New University of LisbonLisbonPortugal

This article aims to approach the“spontaneous healing”of Sister Bernardette Moriau from the view point of transpersonal psychology or psychology of consciousness and also to compare it with the“spiritual awakening”of the philosopher Jiddu ***,within this scope of investigation,this article will refer to the so-called“modified states of consciousness”characteristic of these transcendental experiences,which are promoted by prayer and meditation,leading to“heat release”and“muscle relaxation”.These two cases of studies are part of the so-called“manifestations of the sacred”in the reality of contemporary society,which are studied by the Transcendence *** might contribute to a deeper knowledge of the role and place of ourselves in the Universe.

关键词： altered states of consciousness spontaneous healing and spiritual awakening transpersonal psychology or psychology of consciousness