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Chenopodium ambrosioides induces an endothelium-dependent relaxation of rat isolated aorta

Journal of Integrative Medicine 2019年第2期17卷 115-124页

作者： Asmae Assaidi Ikram Dib Monique Tits Luc Angenot Said Bellahcen nourelhouda bouanani Abdelkhaleq Legssyer Mohammed Aziz Hassane Mekhfi Mohammed Bnouham Michel Frederich Abderrahim Ziyyat Laboratory of Physiology Genetics and Ethnopharmacology Department of Biology Faculty of Sciences Mohammed I University Laboratory of Pharmacognosy Center for Interdisciplinary Research on the Medicines (CIRM) University of Liège

Objective: This study aims to evaluate the vasodilatory effect of Chenopodium ambrosioides on the isolated rat aorta, and to explore its mechanism of ***: The vasorelaxant effect and the mode of action of various extracts from the leaves of C. ambrosioides were evaluated on thoracic aortic rings isolated from Wistar rats. In addition, ethyl acetate and methanol fractions were analyzed, using thin-layer chromatography and high-performance liquid chromatography techniques, for their polyphenolic ***: The various active extracts of C. ambrosioides at four concentrations(10^(-3), 10^(-2), 10^(-1) and 1 mg/mL) relaxed the contraction elicited by phenylephrine, in a concentration-dependent *** effect seems to be endothelium-dependent, since the vasodilatory effect was entirely absent in denuded aortic rings. The vasorelaxant effect of the methanol fraction(MF) of C. ambrosioides at 1 mg/mL was also inhibited by atropine and tetraethylammonium. This effect remained unchanged by Nx-nitro-L-arginine methyl ester hydrochloride and glibenclamide. The preliminary phytochemical analysis showed that the leaves of C. ambrosioides are rich in phenolic and flavonoid ***: These results suggest that the MF of C. ambrosioides produces an endothelium-dependent relaxation of the isolated rat aorta, which is thought to be mediated mainly through stimulation of the muscarinic receptors, and probably involving the opening of Ca^(2+)-activated potassium channels.

关键词： Chenopodium ambrosioides Chenopodiaceae Vasorelaxation Ca^2+-activated potassium channels Thin-layer chromatography High-performance liquid chromatography Plant Complementary and alternative medicine

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A Novel Decoder Based on Parallel Genetic Algorithms for Linear Block Codes

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International Journal of Communications, Network and System Sciences 2013年第1期6卷 66-76页

作者： Abdeslam Ahmadi Faissal El bouanani Hussain Ben-Azza Youssef Benghabrit Department of Communication Networks National High School of Comptuer Science and System Analysis Rabat Morocco Department of Industrial and Production Engineering Moulay Ismail University National High School of Arts and Trades Meknès Morocco

Genetic algorithms offer very good performances for solving large optimization problems, especially in the domain of error-correcting codes. However, they have a major drawback related to the time complexity and memory occupation when running on a uniprocessor computer. This paper proposes a parallel decoder for linear block codes, using parallel genetic algorithms (PGA). The good performance and time complexity are confirmed by theoretical study and by simulations on BCH(63,30,14) codes over both AWGN and flat Rayleigh fading channels. The simulation results show that the coding gain between parallel and single genetic algorithm is about 0.7 dB at BER = 10﹣5 with only 4 processors.

关键词： Channel Coding Linear Block Codes Meta-Heuristics Parallel Genetic Algorithms Parallel Decoding Algorithms Time Complexity Flat Fading Channel AWGN

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Risk Factors and Diabetes Related Complications Frequency in the Population of the Northeastern Morocco

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Open Journal of Epidemiology 2018年第3期8卷 164-185页

作者： Jamila Hammoudi Hassana Dahmani Nourel Houda bouanani Hamid Nouayti Hassane Mekhfi Abdelkhaleq Legssyer Mohamed Bnouham Abderrahim Ziyyat Laboratoire de Physiologie Génétique et Ethnopharmacologie Faculté des Sciences Université Mohammed 1<sup>er</sup> Oujda Morocco Centre de Référence de Diabétologie et des Maladies Chroniques Oujda Morocco

Objectives: Diabetes is one of the most challenging health problems in the 21st century that brings a considerable economic burden on worldwide healthcare resources. Indeed, people with diabetes have a higher lifetime healthcare expenditure due to the long-term complications, which include micro and macrovascular complications. This study sought to estimate the frequency of diabetes complications, and to investigate the associated risk factors. Methodology: Data were obtained from the medical records of 2401 diabetic patients followed at the Reference Center of Diabetes and Chronic Diseases (RCD) in Oujda (Morocco) during the period 2006-2011. Results: Our sample of 2401 diabetic patients include 64.7% women. 32% of patients have one or more complications;retinopathy is the most frequent complication (16.8%), followed by nephropathy (12.4%), cardiovascular diseases (5.4%), neuropathy (3.6%) and diabetes foot (2%). Logistic regression in univariate followed by multivariate analysis has showed that age, duration of diabetes and high albuminuria are the major risk factors for the development of diabetic complications in both type 1 and type 2 diabetes. Conclusions: Nearly one third of diabetic patients were affected by at least one diabetic complication;retinopathy is the most common complication in these patients. Strengthening programs to improve diabetes management and to reduce the risk of these complications should be a high priority in order to control the cost of treatment.

关键词： Diabetic Complications Retinopathy Nephropathy North-Eastern Morocco Risk Factors

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The Dynamics of Suspended Particulate Matter in the Oued Nachef(Tafna Basin,Algeria):Typology of Flood Events and Contribution to Sediment Transport

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Journal of Geological Resource and Engineering 2020年第5期8卷 145-160页

作者： Kazi Tani Hycham Abdesslam bouanani Abderrazak Baba-Hamed Kamila Probst Jean-Luc Laboratory N°25 Dpt.HydraulicInstitute of Science and TechnologyMaghnia University Center13300MaghniaAlgeria Laboratory N°25 Dpt.HydraulicFaculty of TechnologyUniversity Abou Bakr Belkaid13300TlemcenAlgeria Laboratory of Functional Ecology and Environment University of ToulouseCNRSToulouse INPUniversity Toulouse 3-Paul Sabatier(UPS)Toulouse 31062France

This article focuses on the study of sediment transport during flood events in the Oued Nachef watershed that feeds the Mefrouche *** understand the sediment dynamics in this watershed,ANRH data on instantaneous water discharges and the respective concentrations of suspended particulate matter were *** enabled the selection of some of the largest flood events over a 24-year period in order to establish the log-log relationships between sediment load(concentration and flux)and water ***,the discharge-concentration relationships revealed hysteresis phenomena that enabled a flood typology to be established and classified into seven categories,thus showing very different transfer dynamics in relation to flood *** results showed that Category 6 floods presenting hysteresis in the form of a figure of eight exported almost 44%of the suspended particulate matter load while representing just 29%of the flow discharge.

关键词： Algeria Oued Nachef suspended sediment transport flood hysteresis typology

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