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Recurrent Pregnancy Loss in Patients with Polycystic Ovary Syndrome: A Case Control Study

Open Journal of Obstetrics and Gynecology 2017年第11期7卷 1073-1085页

作者： Lulwa Ashaq Yousef al Mazer nourah al qahtani Adan Hospital Al Ahmadi Kuwait Feto-Maternal Medicine Immam Abdulrahman Bin Faisal University Dammam Saudi Arabia

Objectives: To identify different biophysical and hormonal factors that could contribute to recurrent pregnancy loss in Saudi women who have been diagnosed with polycystic ovary syndrome. Study Design: Case-control study. Settings: Infertility clinic in Dammam Maternity and Children Hospital. Cases: PCOS patients with recurrent pregnancy loss. Controls: PCOS patients without recurrent pregnancy loss. Results: The prevalence of recurrent abortion in PCOS patients was 31%. There was no significant difference between the cases and the controls in the age, 33.1 years versus 31.9 years, BMI, 31.4 kg/m2 versus 31.6 kg/m2 respectively. There was no significant difference in the successful pregnancies outcome in cases and controls, term deliveries 84% versus 90%, preterm deliveries 10% versus 5%, twin pregnancy 6% versus 5% respectively. There was no significant difference in the hormonal profile (prolactin, LH, FSH, LH/FSH ratio, TSH, progesterone, testosterone) between cases and controls. Serum estradiol level was significantly lower in the cases compared to the controls, 55.5 pg/mL versus 83.9 pg/mL respectively (p Conclusion: PCOS patients with recurrent abortions had no significant increase in the age, BMI, preterm pregnancy, multiple gestation and ectopic pregnancy. The hormonal profile (prolactin, LH, FSH, LH/FSH ratio, TSH, progesterone, testosterone) was comparable between the cases and the controls, except for serum estradiol level, which was significantly lower in PCOS patients with recurrent abortions.

关键词： Polycystic Ovary Recurrent Abortion

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Induction of Labor with PGE2 after One Previous Cesarean Section: 18 Years Experience in a University Hospital

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International Journal of Clinical Medicine 2011年第1期2卷 35-39页

作者： nourah al qahtani Sameera al Borshaid Hissa al Enezi 不详

Objective: To review the outcome of prostaglandin induction of labor in term pregnant women with previous one ce-sarean section compared to those without previous Cesarean section. Design: 18 years retrospective review of hospital records and case note review of index cases. Setting: University hospital. Population: Three hundred and twenty two women who had their labor induced with prostaglandin E2. One hundred and sixty one women had one previous Ce-sarean section. Methods: This study was conducted at King Fahad University Hospital, University of Dammam. It is a tertiary referral center with approximately 2300 births per year. We searched the hospital's records of deliveries from January 1992 to December 2009 and reviewed all indications and outcomes of prostaglandin induction of labor in women with one previous Cesarean section. The control group was composed of women who had their labor induced with prostaglandin but without previous Cesarean section. Main outcome measures: Labor outcome and uterine rup-ture Results: Three hundred and twenty two women were included. all received prostaglandin E2 for induction of labor. One hundred and sixty one women had one previous Cesarean section (study group) and the rest had no previous Ce-sarean section (control group). There was no difference in the rate of vaginal delivery between study and control group, 68.3% and 79.5% (p value 0.3), respectively. The rate of uterine rupture was 30 times higher in study group (2.5% Vs 0.033%). Conclusion: In women with one previous Cesarean section, induction of labor with prostaglandin leads to comparable rate of vaginal delivery similar to those without prior Cesarean section but with relatively high risk of uter-ine rupture.

关键词： Prostaglandin Induction of Labor Previous Cesarean Section Retrospective

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The Risk of Cesarean Delivery in Short Saudi Women

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International Journal of Clinical Medicine 2012年第3期3卷 238-241页

作者： nourah H. al qahtani Salha al Ganmi Asma Badran Department of Obstetrics and Gynecology College of Medicine University of Dammam Dammam Saudi Arabia.

Objectives: To evaluate the relationship between maternal height of 37 weeks), uncomplicated singleton nulliparous pregnant women were enrolled on admission to labour room. The patients were divided into two groups based on maternal height, >155 cm (247 cases) as control and al records of these women were reviewed. Various baseline clinical characteristics were collected. Maternal characteristics and maternal and neonatal outcomes were recorded. Results: Caesarean section rate for all indications was higher among study group than control group (26.6% and 19.4% respec-tively, p = 0.023). Significant difference was observed in the rate of caesarean delivery due to failure to progress (7.3% and 12% in control and study group respectively, p-value 0.038). The rate of caesarean delivery due to failure to progress was highest among those with height 150 - 155 cm (p-value 0.022). Mean birth weight was significantly higher among control group than study group (3137 ± 403 g and 3030 ± 408 respectively, p-value 0.010). Conclusion: Term singleton nulliparous Saudi pregnant women with maternal height 151 - 154 cm were associated with a greater likelih-ood of caesarean section for failure to progress. Women with height <150 cm did not have increased cesarean section rate. However, mean birth weight was significantly lower in this group.

关键词： Maternal Height Cesarean Delivery Failure to Progress

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Induction of Labor with PGE2 after One Previous Cesarean Section: 18 Years Experience in a University Hospital

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International Journal of Clinical Medicine（临床医学国际期刊） 2011年第1期

作者： nourah al qahtani Sameera al Borshaid Hissa al Enezi

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