检索结果-南通市图书馆

Comment on review article:Chronic hepatitis C virus infection cascade of care in pediatric patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第14期28卷 1494-1498页

作者： nouhoum bouare Mamadou Keita Jean Delwaide Biomedical Sciences National Institute of Public HealthBamako 1771Mali Department of Prevention Medical and Psychosocial ManagementCSLSHIV-TB-HBamako E 595Mali Department of Gastroenterology and Hepatology CHULiegeLiege 4000Belgium

An enhanced cascade of care should include a younger population,helping to achieve the goal of the World Health Organization with a focus on elimination in the pediatric population.Furthermore,enhanced screening and awareness efforts and continued education of health care providers will improve the outcomes of chronic hepatitis C virus(HCV)infection in the pediatric population.The present work discusses and comments on the topic"cascade of care in HCV chronic pediatric patients".

关键词： Cascade of care Hepatitis C virus Chronic patients Pediatric population Disease management Commentary

COVID-19:A pluralistic and integrated approach for efficient management of the pandemic

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Virology 2022年第1期11卷 20-39页

作者： nouhoum bouare Daouda Kassim Minta Abdoulaye Dabo Christiane Gerard Biomedical Sciences Researcher National Institute of Public HealthBamako 1771Mali Department of Infectiology CHU PointGBamako 333Mali Department Epidemiology&Infectiology Disease Faculty Medicine&DentistryCNRST/Univ BamakoBamako 3052Mali Formerly Responsible for the Blood Bank CHU-LiègeUniversity of LiègeLiège 4000Belgium

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which triggered the ongoing pandemic,was first discovered in China in late 2019.SARSCoV-2 is a respiratory virus responsible for coronavirus disease 2019(COVID-19)that often manifests as a pneumonic syndrome.In the context of the pandemic,there are mixed views on the data provided by epidemiologists and the information collected by hospital clinicians about their patients.In addition,the literature reports a large proportion of patients free of pneumonia vs a small percentage of patients with severe pneumonia among confirmed COVID-19 cases.This raises the issue of the complexity of the work required to control or contain the pandemic.We believe that an integrative and pluralistic approach will help to put the analyses into perspective and reinforce collaboration and creativity in the fight against this major scourge.This paper proposes a comprehensive and integrative approach to COVID-19 research,prevention,control,and treatment to better address the pandemic.Thus,this literature review applies a pluralistic approach to fight the pandemic.

关键词： SARS-CoV-2 COVID-19 Pandemic Pluralistic approach Global approach Efficient management

Epidemiological profiles of human immunodeficiency virus and hepatitis C virus infections in Malian women:Risk factors and relevance of disparities

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2013年第4期5卷 196-205页

作者： nouhoum bouare Andre Gothot Jean Delwaide Sebastien Bontems Dolores Vaira Laurence Seidel Paul Gerard Christiane Gerard Department of Clinical Biology Laboratory HematologyImmuno-Hematology and AIDS Reference Laboratory B35Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Department of Hepatology and Gastroenterology Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Department of Public Health(Biostatistics) Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Institute of Mathematics Université de Liège4000 LiègeBelgium

AIM:To document the epidemiologic patterns and risk factors of human immunodeficiency virus(HIV)and hepatitis C virus(HCV)infections in Mali in order to develop prevention means for both diseases.METHODS:Two prospective studies were conducted in Bamako in 2009 among 1000 pregnant women(i.e.,young women)who consulted six reference health centers,and in 2010,among 231 older women who attended general practice in two hospitals.Antibody tests and molecular analysis(performed only for HCV)were used to quantify the frequencies of both infections.The data were collected from patients recruited through a questionnaire.Transmission risk factors of both diseases were identified by univariate and multivariate analysis.RESULTS:HCV seroprevalence was 0.2% for young and 6.5% for older women.HIV prevalence was similar in both populations(4.1% vs 6.1%).In older women,the analysis of risk factors highlighted an association between HCV infection and episodes of hospitalization(P < 0.01).The study did not show an association between HIV infection and the variables such as hospitalization,transfusion,tattoo,dental care,and endoscopy.A significant decrease of HIV seroprevalence was detected in young women who used condoms for contraception more than for other purposes(P < 0.01).By contrast,HIV seroprevalence was significantly increased in young women using condoms mainly to prevent sexual infections rather than for contraception(P < 0.01).No HCV/HIV coinfection was detected in our study.CONCLUSION:Risk factors and epidemiologic data of HIV and HCV as well as the absence of co-infection strongly suggest epidemiological disparities between these diseases.

关键词： Hepatitis C virus Human immunodeficiency virus Epidemiology Risk factors Women Mali Bamako

在 Malian 女人和血清学的试金表演的二张人口的 HIV 和 HCV 感染的流行

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2012年第12期4卷 365-373页

作者： nouhoum bouare Dolores Vaira Andre Gothot Jean Delwaide Sebastien Bontems Laurence Seidel Paul Gerard Christiane Gerard Department of Hematobiology Immuno-Hematology and AIDS Reference Laboratory B35CHU-ULg4000 LiegeBelgium Department of Hepatology and Gastroenterology CHU-ULg4000 LiegeBelgium Department of Public Health(Biostatistics) CHU-ULg4000 LiegeBelgium Institute of Mathematics ULg4000 LiegeBelgium

AIM:To estimate the prevalence of human immunodeficiency virus(HIV) and hepatitis C virus(HCV) infections in women in Mali and to evaluate the performance of serological assays.METHODS:Two prospective studies were conducted in 2009 and 2010 in Mali.They concerned first,1000 pregnant women attending six reference health centers in Bamako(Malian capital) between May 26 and June 16,2009;and secondly,231 women over 50 years who consulted general practitioners of two hospitals in Bamako between October 25 and December 24,2010.Blood samples were collected and kept frozen in good condition before analysis.All samples depicted as positive using HIV/HCV enzyme immuno-assay screening assays were submitted to confirmation analysis.Molecular markers of HCV were characterized.RESULTS:The seroprevalence of HIV and HCV in the population of pregnant women was 4.1% and 0.2% respectively.Among older women the seroprevalence was higher and similar for HIV and HCV(6.1% vs 6.5%).The anti-HIV prevalence was not different in young and older women(4.1% vs 6.1%).In contrast,the anti-HCV prevalence was higher in older compared to younger women(6.5% vs 0.2%,P < 0.01).Of 2 pregnant women who were HCV seropositive,only one was polymerase chain reaction(PCR) reactive and infected by genotype 2,with a viral load of 1600 IU/mL.Regarding older women who were HCV seropositive,13 out of 15 were PCR reactive,infected by genotype 1 or 2.Globally HCV genotype 2 was predominant.The positive predictive value(PPV) measured with VIKIA HIV test in young women was 100% therefore significantly higher than the 87.5% measured in older women(P < 0.05).Conversely,the PPV measured with Monolisa HCV assay in older women was 88.2% and higher than the 14.3% measured in younger women(P < 0.01).CONCLUSION:Whereas HIV prevalence was similar in both subpopulations HCV was more frequent among older women(P < 0.01).The PPV of screening assays varied with the age of the subjects.

关键词： Human immunodeficiency virus Hepatitis C virus Serology Molecular diagnostics Women West Africa Bamako