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Current management of liver diseases and the role of multidisciplinary approach

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World Journal of Hepatology 2022年第11期14卷 1920-1930页

作者： nouhoum bouare Department of Assurance Quality and Biosafety/Biosecurity National Institute of Public HealthBamako 1771Mali

Liver is an organ having extremely diversified functions,ranging from metabolic and synthetic to detoxification of harmful *** multifunctionality of the liver in principle requires the multidisciplinary and pluralistic interventions for its *** studies have investigated liver function,dysfunction and *** editorial work discusses new ideas,challenges and perspectives of current research regarding multidisciplinary and pluralistic management of liver *** one hand the discussions have carried out on the involvement of extracellular vesicles,Na^(+)/H^(+) exchangers,severe acute respiratory syndrome coronavirus 2 and Epstein–Barr virus infections,Drug-induced liver injury,sepsis,pregnancy,and food supplements in hepatic *** the other hand this study has discussed hepatocellular carcinoma algorithms and new bio-chemical and imaging experiments pertaining to liver *** articles with an impact index value">0"from reference citation analysis,which is an open multidisciplinary citation analysis database based on artificial intelligence technology,have served for the study’s *** work may be a useful tool for the clinical practice and research in managing and investigating liver disorders.

关键词： Liver management Liver function Liver dysfunction Liver clinic Liver diagnosis Multidisciplinary approach

Comment on review article:Chronic hepatitis C virus infection cascade of care in pediatric patients

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World Journal of Gastroenterology 2022年第14期28卷 1494-1498页

作者： nouhoum bouare Mamadou Keita Jean Delwaide Biomedical Sciences National Institute of Public HealthBamako 1771Mali Department of Prevention Medical and Psychosocial ManagementCSLSHIV-TB-HBamako E 595Mali Department of Gastroenterology and Hepatology CHULiegeLiege 4000Belgium

An enhanced cascade of care should include a younger population,helping to achieve the goal of the World Health Organization with a focus on elimination in the pediatric ***,enhanced screening and awareness efforts and continued education of health care providers will improve the outcomes of chronic hepatitis C virus(HCV)infection in the pediatric *** present work discusses and comments on the topic"cascade of care in HCV chronic pediatric patients".

关键词： Cascade of care Hepatitis C virus Chronic patients Pediatric population Disease management Commentary

Epidemiological profiles of human immunodeficiency virus and hepatitis C virus infections in Malian women:Risk factors and relevance of disparities

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World Journal of Hepatology 2013年第4期5卷 196-205页

作者： nouhoum bouare Andre Gothot Jean Delwaide Sebastien Bontems Dolores Vaira Laurence Seidel Paul Gerard Christiane Gerard Department of Clinical Biology Laboratory HematologyImmuno-Hematology and AIDS Reference Laboratory B35Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Department of Hepatology and Gastroenterology Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Department of Public Health(Biostatistics) Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Institute of Mathematics Université de Liège4000 LiègeBelgium

AIM:To document the epidemiologic patterns and risk factors of human immunodeficiency virus(HIV)and hepatitis C virus(HCV)infections in Mali in order to develop prevention means for both ***:Two prospective studies were conducted in Bamako in 2009 among 1000 pregnant women(i.e.,young women)who consulted six reference health centers,and in 2010,among 231 older women who attended general practice in two *** tests and molecular analysis(performed only for HCV)were used to quantify the frequencies of both *** data were collected from patients recruited through a *** risk factors of both diseases were identified by univariate and multivariate ***:HCV seroprevalence was 0.2% for young and 6.5% for older *** prevalence was similar in both populations(4.1% vs 6.1%).In older women,the analysis of risk factors highlighted an association between HCV infection and episodes of hospitalization(P < 0.01).The study did not show an association between HIV infection and the variables such as hospitalization,transfusion,tattoo,dental care,and endoscopy.A significant decrease of HIV seroprevalence was detected in young women who used condoms for contraception more than for other purposes(P < 0.01).By contrast,HIV seroprevalence was significantly increased in young women using condoms mainly to prevent sexual infections rather than for contraception(P < 0.01).No HCV/HIV coinfection was detected in our ***:Risk factors and epidemiologic data of HIV and HCV as well as the absence of co-infection strongly suggest epidemiological disparities between these diseases.

关键词： Hepatitis C virus Human immunodeficiency virus Epidemiology Risk factors Women Mali Bamako

Prevalence of HIV and HCV infections in two populations of Malian women and serological assays performances

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World Journal of Hepatology 2012年第12期4卷 365-373页

作者： nouhoum bouare Dolores Vaira Andre Gothot Jean Delwaide Sebastien Bontems Laurence Seidel Paul Gerard Christiane Gerard Department of Hematobiology Immuno-Hematology and AIDS Reference Laboratory B35CHU-ULg4000 LiegeBelgium Department of Hepatology and Gastroenterology CHU-ULg4000 LiegeBelgium Department of Public Health(Biostatistics) CHU-ULg4000 LiegeBelgium Institute of Mathematics ULg4000 LiegeBelgium

AIM: To estimate the prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections in women in Mali and to evaluate the performance of serological assays.

关键词： Human immunodeficiency virus Hepatitis C virus Serology Molecular diagnostics Women West Africa Bamako

COVID-19:A pluralistic and integrated approach for efficient management of the pandemic

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World Journal of Virology 2022年第1期11卷 20-39页

作者： nouhoum bouare Daouda Kassim Minta Abdoulaye Dabo Christiane Gerard Biomedical Sciences Researcher National Institute of Public HealthBamako 1771Mali Department of Infectiology CHU PointGBamako 333Mali Department Epidemiology&Infectiology Disease Faculty Medicine&DentistryCNRST/Univ BamakoBamako 3052Mali Formerly Responsible for the Blood Bank CHU-LiègeUniversity of LiègeLiège 4000Belgium

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which triggered the ongoing pandemic,was first discovered in China in late ***-2 is a respiratory virus responsible for coronavirus disease 2019(COVID-19)that often manifests as a pneumonic *** the context of the pandemic,there are mixed views on the data provided by epidemiologists and the information collected by hospital clinicians about their *** addition,the literature reports a large proportion of patients free of pneumonia vs a small percentage of patients with severe pneumonia among confirmed COVID-19 *** raises the issue of the complexity of the work required to control or contain the *** believe that an integrative and pluralistic approach will help to put the analyses into perspective and reinforce collaboration and creativity in the fight against this major *** paper proposes a comprehensive and integrative approach to COVID-19 research,prevention,control,and treatment to better address the ***,this literature review applies a pluralistic approach to fight the pandemic.

关键词： SARS-CoV-2 COVID-19 Pandemic Pluralistic approach Global approach Efficient management