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World Journal of Cardiology 2014年第6期6卷 424-433页

作者： Rodrigo Estévez-Loureiro ángela López-Sainz Armo Pérez de Prado Carlos Cuellas Ramón Calvio Santos norberto alonso-orcajo Jorge Salgado Fernández Jose Manuel Vázquez-Rodríguez Maria López-Benito Felipe Fernández-Vázquez Division of Cardiology Complejo Asistencial Universitario de León (CAULE)24071 LeonSpain Division of Cardiology Complejo Hospitalario Universitario A Coru?a (CHUAC)15006 La Coru?aSpain

Primary percutaneous coronary intervention(PPCI) is the preferred reperfusion therapy for patients presenting with ST-segment elevation myocardial infarction(STEMI) when it can be performed expeditiously and by experienced operators. In spite of excellent clinical results this technique is associated with longer delays than thrombolysis and this fact may nullify the benefit of selecting this therapeutic option. Several strategies have been proposed to decrease the temporal delays to deliver PPCI. Among them,prehospital diagnosis and direct transfer to the cath lab,by-passing the emergency department of hospitals,has emerged as anattractive way of diminishing delays. The purpose of this review is to address the effect of direct transfer on time delays and clinical events of patients with STEMI treated by PPCI.

关键词： Primary angioplasty Direct transfer STsegment elevation myocardial infarction network Primary percutaneous coronary intervention Myocardial infarction

Epidemiologic characteristics of death by burn injury from 2000 to 2009 in Colombia, South America:a population-based study

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Burns & Trauma 2016年第1期4卷 60-67页

作者： norberto Navarrete Nelcy Rodriguez Burn Intensive Care Unit Simón Bolívar HospitalBogotáColombia. ClinicalEpidemiology and Biostatistics Department Javeriana UniversityBogotáColombia. Department of Statistics National University of ColombiaBogotáColombia.

Background:Burns are one of the most severe traumas that an individual can *** World Health Organization(WHO)affirms that injuries related to burns are a global public health problem mainly in low-and middle-income *** first step towards reducing any preventable injury is based on accurate *** Colombia,the basic epidemiological characteristics of burn injuries are *** objectives were establishing the causes,high-risk populations,mortality rate,and tendencies of burn ***:Observational,analytical,population-based study based on official death certificate occurred between 2000 and *** codes of the International Classification of Diseases-10th Revision(ICD-10)related to burns were *** mortality rates were standardized using the WHO world average age weights 2000–*** determine the tendency,an average annual percent change(AACP)was ***:A total of 5448 deaths due to burns were identified;78.4%were *** crude and adjusted burn mortality rate was 1.270 and 1.302 per 100,000,*** AACP was?5.25%.Electrical injury caused the greatest number of deaths(49.5%),followed by fire and lightning injuries.A total of 1197(22.1%)children were under 15 years *** causes of deaths were different among age groups.59.4%deaths occurred outside health ***:This study is a first step in identifying the main causes of death and groups with higher mortality *** is the main cause of deaths due to burn *** research is required in order to generate awareness among government and community for reducing the number of injuries and burn deaths in our country.

关键词： injuries injury characteristics

The endemic Patagonian vespertilionid assemblage is a depauperate ecomorphological vicariant of species-rich neotropical assemblages

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Current Zoology 2017年第5期63卷 495-505页

作者： Analia L. GIMENEZ norberto P, GIANNINI Centro de Investigacion Esquel de Montafia y Estepa Patagonicas (CIEMEP CONICET-UNPSJB) Laboratorio de Investigaciones en Evoluci6n y Biodiversidad (LIEB) Roca 780 Esquel Chubut CP 9200 Argentina Unidad Ejecutora Lillo Consejo Nacional de Investigaciones Cientfficas y Tecnicas (CONICET) Fundacion Miguel Lillo Facultad de Ciencias Naturales e Instituto Miguel Lillo Universidad Nacional de Tucuman San Miguel de Tucuman Tucuman Argentina

Vespertilionidae is the most diverse chiropteran family, and its diversity is concentrated in warmregions of the World; however, due to physiological and behavioral adaptations, these bats alsodominate bat faunas in temperate regions. Here we performed a comparative study of vespertili-onid assemblages from two broad regions of the New World, the cold and harsh Patagonia, versusthe remaining temperate-to-subtropical, extra-Patagonian eco-regions of the South AmericanSouthern Cone. We took an ecomorphological approach and analyzed the craniodental morpho-logical structure of these assemblages within a phylogenetic framework. We measured 17 cranio-dental linear variables from 447 specimens of 22 currently recognized vespertilionid species of thestudy regions. We performed a multivariate analysis to define the morphofunctional space, andcalculated the pattern and degree of species packing for each assemblage. We assessed the im-portance of phylogeny and biogeography, and their impact on depauperate （Patagonian） versusrich （extra-Patagonian） vespertilionid assemblages as determinants of morphospace *** implemented a sensitivity analysis associated to small samples of rare species. The morpho-logical patterns were determined chiefly by the evolutionary history of the family. The Patagonianassemblage can be described as a structurally similar but comparatively depauperate ecomorpho-logical version of those assemblages from neighboring extra-Patagonian eco-regions. ThePatagonian assemblage seems to have formed by successively adding populations from Northernregions that eventually speciated in the region, leaving corresponding sisters （vicariants） in extra-Patagonian eco-regions that continued to be characteristically richer. Despite being structurallyakin, degree of species packing in Patagonia was comparatively very low, which may reflect the ef-fect of limited dispersal success into a harsh region for bat survival.

关键词： Vespertilionidae, Patagonia, morphological space, biogeography, phylogeny.

Parameters Affecting the Fuel Cell Reactions on Platinum Bimetallic Nanostructures

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Electrochemical Energy Reviews 2023年第1期6卷 830-853页

作者： Nicolas alonso‑Vante IC2MP UMR-CNRS 7285University of Poitiers4 rue Michel Brunet86072 PoitiersFrance

In this paper the electrochemical properties of some platinum-based nanoalloys are *** revision is centered on electrocatalytic materials generated via the carbonyl chemical route(CCR).In considering the effects of segregation in these bimetals,the reaction of the hydrogen oxidation(HOR)and oxygen reduction(ORR)in the alkaline medium was *** reaction kinetics of these electrochemical processes in the alkaline electrolyte is still a *** the design of high-performance platinum-based electrocatalysts,it is of importance to know that the kinetics of HOR and ORR also depends on the Pt *** electrochemical analysis,based on the study of Pt nanoalloyed surfaces with different Pt-adsorbate interactions,was taken into account.A clear trend in the HOR as well as the ORR activity,in the alkaline electrolyte,was established,revealing that the activity changes in the order PtSn/C

关键词： Electrocatalysts HOR HER ORR Pt-based materials Bimetallic Carbon domains

Very-early-stage Hepatocellular Carcinoma,Are We at Long Last on Route for Achieving Better Patient Outcomes?

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Journal of Clinical and Translational Hepatology 2021年第2期9卷 141-142页

作者： Paulina Vidal-Cevallos norberto Chavez-Tapia Obesity and Digestive Disease Unit Medica Sur Clinic and FoundationMexico CityMexico

Hepatocellular carcinoma(HCC)represents∼90%of the primary liver cancer cases,and 90%of HCC cases occur in patients with chronic liver disease.1 It also represents the sixth most common cancer(4.7%)and the third leading cause of cancer-related death globally(8.3%).2 More troubling,the global incidence and mortality rates have been increasing since 1990.3 In the United States,the highest average annual percentage change(known as AAPC)reported between 2000 and 2012 involved individuals between 55 and 59 years of age(AAPC:8.9%;95%confidence interval:7.1–10.7%).

关键词： Carcinoma mortality cancer

Flow near a model spur dike with a fixed scoured bed

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International Journal of Sediment Research 2013年第3期28卷 349-357页

作者： Roger KUHNLE Carlos alonso National Sedimentation Laboratory U.S.Department of AgricultureAgricultural Research Service

Three-dimensional flow velocities were measured using an acoustic Doppler velocimeter at a closely spaced grid over a fixed scoured bed with a submerged spur ***-dimensional flow velocities were measured at 3,484 positions around the trapezoidal shaped submerged model spur *** velocity distributions and detailed near field flow structures were revealed by the *** differences were revealed between flow over fixed flat and scoured *** lateral flows were the dominant cause of the observed local *** stresses were higher for the scoured bed than in the flat bed *** rates of scour as the scour hole developed were attributed to increases in critical shear stress in the scour holes caused by the increase in the length and magnitude of adverse slopes associated with the two main scour holes.

关键词： Submerged spur dike 3-dimensional flow Velocity measurements Free surface flow Hydraulic structure

CATALYTIC CONVERSION OF MUNICIPAL WASTE PLASTIC INTO GASOLINE-RANGE PRODUCTS OVER MESOPOROUS MATERIALS

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China Particuology 2006年第2期4卷 80-82页

作者： Jorge norberto Beltramini ARC Centre for Functional NanomaterialsThe University of Queensland Brisbane Queensland 4072 Australia

In the last 20 years, it has become apparent that waste produced from plastics was becoming an environmental problem because of their low biodegradability. Though several methods have been proposed for recycling waste plastics, it is generally accepted that material recovery is not a long-term solution to the present problem, and that energy or chemical recovery is a more attractive alternative, including cracking into the monomer constituents, combustion to produce energy, and thermal or catalytic conversion to produce useful intermediate chemicals. This paper is a contribution in the area of the last option for energy recovery. There have been a number of publications reporting the use of molecular sieves and amorphous silica-alumina catalysts for the cracking of polymers into a range of hydrocarbons. The research work reported here demonstrates the ability of mesoporous catalysts in cracking polyethyl- ene into gasoline range products. It was found that for mesoporous MCM-41 catalysts, its cracking activity increases with its crystallinity, displaying higher activity with smaller pore diameters. The hydrocarbon product distribution strongly indicates a carbenium ion cracking mechanism. The product distribution was also compared with those obtained from thermal cracking tests.

关键词： waste plastic mesoporous materials polyethylene cracking MCM-41

Bigger or long-winged male common crossbills exhibit redder carotenoid-based plumage coloration

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Current Zoology 2023年第2期69卷 165-172页

作者： Blanca Fernandez-Eslava Daniel alonso David Galicia Juan Arizaga Carlos alonso-Alvarez Biologia Ambiental Universidad de NavarraFacultad de CienciasC/Irunlarrea1 Pamplona31008 NavarraSpain Ornitologia Sociedad de Ciencias de AranzadiZorroagagaina 1120014 DonostiaSan SebastianSpain Ecologia Evolutiva Museo Nacional de Ciencias Naturales(CSiC)Edificio Pinar 2528006 MadridSpain

Carotenoid-based ornaments are often considered reliable(honest)individual condition signals because their expression implies physiological costs unaffordable for low-quality animals(handicap signals).Recently,it has been suggested that efficient cell respiration is mandatory for producing red ketocarotenoids from dietary yellow *** implies that red colorations should be entirely unfalsifiable and independent of expression costs(index signals).In a precedent study,male common crossbills,Loxia curvirostra,showing a red plumage reported higher apparent survival than those showing yellowish-orange *** plumage redness in this species is due to ketocarotenoid accumulation in ***,we correlated the male plumage redness(a 4-level visual score:yellow,patchy,orange,and red)and the body morphology in more than 1,ooo adult crossbills captured in 3 Iberian localities to infer the mechanisms responsible for color evolution.A principal component analysis summarized morphometry of 10 variables(beak,wing,tarsus length,etc.).The overall body size(PC1)and the length of flight feathers regarding body size(Pc3)showed significant positive relationships with plumage *** redness was barely correlated with bill shape measures,suggesting no constraint in acquiring carotenoids from pine ***,large body sizes or proportionally long flying feathers could help carotenoid acquisition via social competition or increased foraging *** longer flight feathers might also be associated with a specific cell respiration profile that would simultaneously favor flying capacities and enzymatic transformations needed for ketocarotenoid *** a phenotypic profile would agree with the hypothesis of ketocarotenoid-based colors acting as individual quality index signals.

关键词： avian carotenoids color and biometrics Loxia genus Mediterranean crossbills resource allocation trade-offs shared pathway hypothesis

Back-to-Front Ordering of Triangles in Digital Terrain Models over Regular Grids

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Journal of Computer Science & Technology 2018年第6期33卷 1192-1203页

作者： Jesús alonso Robert Joan-Arinyo Informatics in Engineering Group Technical University of Catalonia 08028 Barcelona Catalonia Center for Biomedical Engineering Research Sant Joan de Ddu Research Institute 08028 Barcelona Catalonia Visualization Interaction and Virtual Reality Group Technical University of Catalonia 08028 Barcelona Catalonia

Visiting triangles that conform a digital terrain model is a core operation in a number of fields like animationand video games or generating profiles, cross-sections, and contours in civil engineering. Perfornfing the visit in an efficientmanner is an issue specially when the output of the traversal depends in some way on additional parameters or informationchanging over time, for example, a moving point of view. In this work we report a set of rules that, given a digital terrainmodel defined over a regular grid and an arbitrary point of view outside the terrain, define a total back-to-front order in theset of digital terrain model triangles with respect to the point. The set of rules is minimal, complete and correct. To assesshow the rules perform, we have implemented a CPU-based algorithm for realistically rendering height fields defined overregular grids. The algorithm does not make use of the z-buffer or shaders featured by our graphics card. We show how ouralgorithm is implemented and show visual results obtained from synthetic and real data. We further discuss the algorithmperformance with respect to two algorithms： a naive algorithm that visits triangles according to grid indices and does notsolve the hidden line problem, and the z-buffer provided by the graphics card featured by our computer. Our algorithmallows real-time interaction when the point of view arbitrarily moves in 3D space and we show that its performance is asgood as that of the z-buffer graphics card.

关键词： back-to-front ordering digital terrain model elevation terrain model triangle strip, visibility

Translational approaches: From fatty liver to non-alcoholic steatohepatitis

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World Journal of Gastroenterology 2014年第27期20卷 9038-9049页

作者： Natalia Rosso norberto C Chavez-Tapia Claudio Tiribelli Stefano Bellentani Fondazione Italiana Fegato 34149 Trieste Italy Obesity and Digestive Diseases Unit Médica Sur Clinic and FoundationMexico 14050 México Department of Medical Sciences University of Trieste Department of Gastroenterology and Endoscopy Azienda USL di ModenaOspedale "Ramazzini" 41012 Carpi (Modena) Italy

Over the past few decades, non-alcoholic fatty liver disease(NAFLD) has become one, if not the most common,cause of chronic liver disease affecting both adults and children. The increasing number of cases at an early age is the most worrying aspect of this pathology, since it provides more time for its evolution. The spectrum of this disease ranges from liver steatosis to steatohepatitis, fibrosis and in some cases, hepatocellular carcinoma. NAFLD may not always be considered a benign disease and hepatologists must be cautious in the presence of fatty liver. This should prompt the use of the available experimental models to understand better the pathogenesis and to develop a rational treatment of a disease that is dangerously increasing. In spite of the growing efforts, the pathogenesis of NAFLD is still poorly understood. In the present article we review the most relevant hypotheses and evidence that account for the progression of NAFLD to non-alcoholic steatohepatitis(NASH) and fibrosis. The available in vitro and in vivo experimental models of NASH are discussed and revised in terms of their validity in translational studies. These studies must be aimed at the discovery of the still unknown triggers or mediators that induce the progression of hepatic inflammation, apoptosis and fibrosis.

关键词： Fatty Liver Obesity Metabolic syndrome Inflammation In vitro Experimental model