检索结果-南通市图书馆

Forensic profiling of non-volatile organic compounds in soil using ultra-performance liquid chromatography:a pilot study

引用

Forensic Sciences Research 2022年第4期7卷 761-773页

作者： Loong Chuen Lee Ab Aziz Ishak Ameeta A/P Nai Eyan Anas Fahmi Zakaria Nurul Syahiera Kharudin nor azman mohd noor Program of Forensic Sciences Centre for DiagnosticTherapeutic&Investigative StudiesFaculty of Health SciencesUniversiti Kebangsaan MalaysiaBangiMalaysia Institute of IR4.0 Universiti Kebangsaan MalaysiaBangiMalaysia Makmal Forensik Polis DiRaja Malaysia(PDRM) CherasMalaysia

Soil is of particular interest to the forensic community because it can be used as valuable associative evidence to link a suspect to a victim or a crime *** chromatography is a powerful analytical tool for organic compound ***,high-performance liquid chromatography(HPLC)has proven to be an efficient method for forensic soil analysis,especially in discriminating soils from proximity ***,ultra-performance liquid chromatography(UPLC),which is much more sensitive than HPLC,has never been explored in this *** study proposed a UPLC method for profiling non-volatile organic compounds in three Malaysian soils(red,brown and yellowish-brown soils).The three soils were analysed separately to assess the effects of individual chromatographic parameters:(a)elution programme(isocratic *** gradient programmes);(b)flow rate(0.1 vs.0.2 mL/min);(c)extraction solvent(acetonitrile ***)and(d)detection wavelength(230 vs.254 nm).The injection volume and total run time were set to 5μL and 35 min,***,each soil sample gave 24 different *** showed that the most desirable chromatographic parameters were(a)isocratic elution;(b)flow rate at 0.2 mL/min and(c)acetonitrile extraction *** proposed UPLC system is expected to be a feasible method for profiling non-volatile organic compounds in soil,and is more chemical-efficient than a comparable HPLC system.

关键词： Forensic sciences soil non-volatile organic compound liquid chromatography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proapoptotic activities of Oroxylum indicum leave extract in HeLa cells

引用

Asian Pacific Journal of Tropical Biomedicine 2019年第8期9卷 339-345页

作者： Nurul Hidayah Wahab Nur Afina mohd Din Yee Ying Lim noor Izani noor Jamil nor Fazila Che Mat School of Health Sciences Health Campus Universiti Sains Malaysia

Objective: To examine the proapoptotic properties of Oroxylum indicum methanol extract on cervical cancer cells. Methods: Methylene blue assay was used to determine the IC50 value of the extract. Western blotting assays were done to analyze the expression of HPV oncoproteins (HPV18 E6 and E7) and apoptotic molecules (caspase-3 and caspase-8). Reverse transcriptase PCR assays were performed to determine genetic alteration of tumor suppressors p53 and pRb and apoptosis markers Fas and FasL. Enzyme-linked immunosorbent assay (ELISA) was done to determine the expression of cytokine levels (IL-6 and IL-12). Results: The determination of IC50 value indicated a higher anti-proliferative activity of the extract compared to cisplatin. After 24 hours of treatment, Western blot analysis showed that treated HeLa cells exhibited a significant down-regulation of HPV18 oncoproteins E6 and E7, and a significant induction of caspase-8 and caspase-3 activation level. Meanwhile, the mRNA expressions of p53, pRb, Fas and FasL were significantly upregulated in treated cells. Moreover, ELISA showed an increased IL-12 and decreased IL-6 production after Oroxylum indicum treatment. Conclusions: The methanol extract of Oroxylum indicum has an anti-proliferative activity and proapoptotic potential. It induces localized-immunity improvements by altering cytokine production in HPV-positive cervical cancer cells.

关键词： Oroxylum indicum Proapoptotic Anti-proliferative HeLa cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chicken Eggshell as an Innovative Bioflocculant in Harvesting Biofloc for Aquaculture Wastewater Treatment

引用

Journal of Renewable Materials 2023年第5期11卷 2321-2332页

作者： Hajjar Hartini Wan Jusoh nor azman Kasan Hidayah Manan Nurfarahana mohd Nasir Fareza Hanis mohd Yunos Sofiah Hamzah Ahmad Jusoh Faculty of Ocean Engineering Technology and Informatics Universiti Malaysia TerengganuKuala NerusTerengganu21030Malaysia Institute of Tropical Aquaculture and Fisheries(AKUATROP) Universiti Malaysia TerengganuKuala NerusTerengganu21030Malaysia Faculty of Engineering Universiti Putra MalaysiaUPM SerdangSelangor Darul Ehsan43400Malaysia

Implementation of biofloc technology(BFT)system in aquaculture industry shows high productivity,low feed conversion ratio,and an optimum culture *** study was divided into two *** first phase involved maintaining the water quality using the optimum carbon-to-nitrogen ratio by manipulating pH in culture *** second phase examined the performance of harvesting biofloc(remaining phytoplankton and suspended solids in the system)using chicken eggshell powder(CESP).This study showed that pH 7 to 8 were the best biofloc performance with high removal percentage of ammonia(>99%)with a remaining ammonia concentration of 0.016 mg L^(−1)and 0.018 mg L^(−1),*** second phase of this study was performed to determine the optimal formulation and conditions of using CESP as a bio-flocculant in harvesting excess *** use of eggshell showed a higher harvesting efficiency of more than 80%under the following treatment conditions:0.25 g L^(−1)of eggshell dosage;with rapid and slow mixing rates of 150 and 30 rpm,respectively;30 min of settling time;settling velocity of 0.39 mm s^(−1)and pH of 6 to ***,the results indicated that biofloc would be the best green technology approach for sustainable aquaculture wastewater and the CESP is an organic matrix that environmental-friendly bio-coagulant for biofloc harvesting.

关键词： Chicken eggshell aquaculture biofloc coagulant water quality harvesting

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The protective effects of procyanidin C-1 on bisphenol A-induced testicular dysfunction in aged mice

引用

Food Science and Human Wellness 2022年第4期11卷 965-974页

作者： Mastura Abd Malek Razif Dasiman nor-Ashikin Mohamed noor Khan Sofee Mohamed-Akhlak mohd-Hafi zi Mahmud Maternofetal and Embryo Research Group(MatE) Faculty of MedicineUniversiti Teknologi MARASelangor BranchSungai Buloh Campus47000 Sungai BulohSelangorMalaysia Faculty of Health Sciences Universiti Teknologi MARASelangor BranchPuncak Alam Campus42300 Puncak AlamSelangorMalaysia

The number and quality of sperm are decreased due to bisphenol A(BPA) exposure, an endocrine-disrupting chemical on the male reproductive system, especially in advanced paternal age(APA). Procyanidin C-1(PCY-1), an antioxidant from grape seed(Vitis vinifera L.), has demonstrated anti-viral, anti-melanogenic and immunostimulatory effects. Therefore, this study aims to determine the effects of PCY-1 intervention on sperm parameters, testis morphological changes, serum testosterone, oestradiol, and luteinizing hormone(LH) concentrations and the expression of apoptotic(Bax and Bcl-2) and mitochondria-related(Mfn1 and Opa1) genes in BPA-exposed aged mice. Results revealed that PCY-1 intervention improves aged male fertility in BPA-exposed conditions by decreasing abnormal sperms percentage and increasing spermatogenic cell diameter and epithelial height. PCY-1 also decreased oestradiol, and increased LH and testosterone levels. The gene expression of Bax was significantly down-regulated by PCY-1 intervention. In contrast, Bcl-2 was substantially up-regulated. Expression of Mfn1 and Opa1 genes were also significantly up-regulated in the PCY intervention group. Hence, it is demonstrated that PCY-1 was able to mitigate the adverse effects of BPA on reproductive parameters of aged mice. Collectively, we postulated that PCY-1 has a potential role in protecting the ageing male reproductive system against the damaging impacts of BPA.

关键词： Apoptosis Bisphenol A Procyanidin Mitochondrial dynamics Testis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism

引用

Nano-Micro Letters 2015年第3期7卷 219-242页

作者： Amna Sirelkhatim Shahrom Mahmud azman Seeni noor Haida Mohamad Kaus Ling Chuo Ann Siti Khadijah mohd Bakhori Habsah Hasan Dasmawati Mohamad Nano-Optoelectronics Research and Technology Laboratory (N.O.R.Lab) School of Physics Universiti Sains Malaysia Advanced Medical and Dental Institute Cluster of Integrative Medicine Universiti Sains Malaysia School of Chemical Sciences Universiti Sains Malaysia Nano-Optoelectronics Research and Technology Laboratory(N.O.R.Lab) School of Physics Universiti Sains Malaysia Department of Medical Microbiology Parasitology and Immunology School of Medical Sciences Universiti Sains Malaysia School of Dental Sciences Universiti Sains Malaysia

Antibacterial activity of zinc oxide nanoparticles(Zn O-NPs) has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region. Many microorganisms exist in the range from hundreds of nanometers to tens of micrometers. Zn O-NPs exhibit attractive antibacterial properties due to increased specific surface area as the reduced particle size leading to enhanced particle surface reactivity. Zn O is a bio-safe material that possesses photo-oxidizing and photocatalysis impacts on chemical and biological species. This review covered Zn O-NPs antibacterial activity including testing methods, impact of UV illumination, Zn O particle properties(size, concentration, morphology, and defects), particle surface modification, and minimum inhibitory concentration. Particular emphasize was given to bactericidal and bacteriostatic mechanisms with focus on generation of reactive oxygen species(ROS) including hydrogen peroxide(H2O2), OH-(hydroxyl radicals), and O2-2(peroxide). ROS has been a major factor for several mechanisms including cell wall damage due to Zn O-localized interaction, enhanced membrane permeability, internalization of NPs due to loss of proton motive force and uptake of toxic dissolved zinc *** have led to mitochondria weakness, intracellular outflow, and release in gene expression of oxidative stress which caused eventual cell growth inhibition and cell death. In some cases, enhanced antibacterial activity can be attributed to surface defects on Zn O abrasive surface texture. One functional application of the Zn O antibacterial bioactivity was discussed in food packaging industry where Zn O-NPs are used as an antibacterial agent toward foodborne diseases. Proper incorporation of Zn O-NPs into packaging materials can cause interaction with foodborne pathogens, thereby releasing NPs onto food surface where they come in contact with bad bacteria and cause the bacterial death and/or in

关键词： Antibacterial activity Zn O-NPs Toxicity mechanism Reactive oxygen species Zinc ions release Food antimicrobial

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Etiologies of tropical acute febrile illness in West Pahang, Malaysia: A prospective observational study

引用

Asian Pacific Journal of Tropical Medicine 2020年第3期13卷 115-122页

作者： Alif Adlan mohd Thabit mohd Hatta Abdul Mutalip Wan mohd Rasis Wan Ahmad Kamil mohd Ramadhanmohd Din Mohan Arumugam Siti Sanaa Wan azman Roslinda Jaafar Sathvinder Singh Gian Singh RafidahAbdullah Eida Nurhadzira Muhammad nor Asiah Muhamad Department of Medicine Hospital Bentong BentongPahangMalaysia Institute for Public Health National Institute of HealthMalaysiaMinistry of Health MalaysiaSelangorMalaysia Department of Medicine Hospital Sultan Haji Ahmad Shah TemerlohPahangMalaysia Department of Pathology Hospital Sultan Haji Ahmad Shah TemerlohPahangMalaysia Department of Medicine Hospital Kuala Lipis Kuala LipisPahangMalaysia

Objective: To determine the etiologies of tropical acute febrile illness(TAFI) in West Pahang, Malaysia and to investigate morbidity and mortality factors in relation to TAFI. Methods: A multicenter prospective cohort study was conducted between January and June 2016 in six district hospitals throughout the western part of Pahang State in Peninsular Malaysia. A total of 336 patients answered a standardized questionnaire and blood samples were collected for laboratory confirmation of infectious etiology. Descriptive analysis and logistic regression were performed to identify factors associated with TAFI. Results: A total of 336 patients were included. The patients were mainly Malays(70.2%), males(61.3%), aged(44.6±17.4) years, with more than half(58.9%) presenting with gastrointestinal symptoms. The majority were diagnosed with dengue(35.7%) while malaria(4.5%) was the least frequent. The in-hospital mortality due to TAFI was 9.2%. Patients with meliodosis had five times higher mortality [Adjusted OR: 5.002, 95% CI:(1.233, 20.286)]. Patients with comorbidities such as cardiovascular symptoms(P<0.001) and renal replacement therapy initiation(P<0.001) were significantly associated with in-hospital mortality in all TAFI. Conclusions: The etiology of TAFI in the western Pahang includes dengue, leptospirosis, malaria and melioidosis, which carry the highest risk of in-hospital mortality. The presence of cardiovascular symptoms may be used to assess the disease severity in TAFI, but more studies are needed in the future.

关键词： Comorbidities Mortality Tropical acute febrile illness

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A review of gynogenesis manipulation in aquatic animals

引用

Aquaculture and Fisheries 2022年第1期7卷 1-6页

作者： Hidayah Manan A.B.noor Hidayati Nur Aina Lyana Adnan Amin-Safwan Hongyu Ma nor azman Kasan Mhd Ikhwanuddin Higher Institution Centre of Excellence(HICoE) Institute of Tropical Aquaculture and FisheriesUniversiti Malaysia Terengganu21030 Kuala NerusTerengganuMalaysia Institute of Biological Science Faculty of ScienceUniversity of MalayaKuala Lumpur50603Malaysia Guangdong Provincial Key Laboratory of Marine Biotechnology Shantou UniversityShantou515063China STU-UMT Joint Shellfish Research Laboratory Shantou UniversityShantou515063China

Gynogenesis is an established technique to generate all female type offspring and this technique has been successfully induced diploid gynogens progeny in aquatic animals of fishes and *** culture of all female shrimp and fishes were selected attribute to all female type offspring which have better size than male and help increase the market size and *** article discusses on the protocol applied to produce gynogens progeny and the successful rate of gynogenesis production in fishes,molluscs and aquatic crustaceans of shrimps in *** most of the UV length applied for irradiated the sperm were around 254-365 nm for(20-40 s),(20-80 s)and(5-8 s)for shrimps,254 nm,30 s for molluscs species and for fishes were around 254 nm for(1.5min)and(2-12 min)time of exposure *** gynogenesis induction,the fertilized eggs were treated with cold shock,heat shock or cytochalasin-B for both shrimp and fishes gynogens *** rate was identified around 4.33%-19.67%in *** hatching rate was identified around 3.0%,14.9%-37.2%of gynogens offspring in shrimp and various percentages of hatching rates were identified from each species of fish ***,there is still low survival rate of gynogens produced using gynogenesis technique and further study should be carried out to improve the gynogens *** discussed protocols serve as a guide lines for the gynogenesis technique application of all female monosex culture in the future.

关键词： UV-Length Irradiated sperm Fertilized eggs Hatching rate Survival rate Gynogens

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Demethylbelamcandaquinone B from Marantodes pumilum ***(Blume)Kuntze inhibits osteoclast differentiation in RAW264.7 cells

引用

Asian Pacific Journal of Tropical Biomedicine 2021年第12期11卷 535-542页

作者： Haryati Ahmad Hairi Jamia Azdina Jamal nor Ashila Aladdin Khairana Husain noor Suhaili mohd Sofi norazlina Mohamed Isa Naina Mohamed Ahmad Nazrun Shuid Department of Biochemistry Faculty of MedicineManipal University College MalaysiaJalan Batu HamparBukit Baru75150 MelakaMalaysia Faculty of Pharmacy Universiti Kebangsaan MalaysiaJalan Raja Muda Abdul Aziz50300 Kuala LumpurMalaysia Department of Pharmacology Faculty of MedicinePreclinical BuildingUniversiti Kebangsaan MalaysiaJalan Yaacob LatiffBandar Tun RazakCheras56000 Kuala LumpurMalaysia Department of Pharmacology Faculty of MedicineUniversiti Teknologi MaraJalan Hospital47000 Sungai BulohSelangorMalaysia

Objective:To investigate the bone-resorbing effect of demethylbelamcandaquinone B(Dmcq B)extracted from Marantodes pumilum *** on osteoclast differentiation in RAW264.7 ***:RAW264.7 macrophages were differentiated using RANKL into osteoclast-like ***,they were treated with 10μg/mL Marantodes pumilum *** crude aqueous extract,5μg/mL dichloromethane fraction,and 0.6μg/mL Dmcq B and 0.06μg/mL ***-resistant acid phosphatase 5b(TRACP 5b)as an osteoclast phenotypic marker was determined by TRACP staining and TRACP 5b colometric assay,and bone-resorbing pits were *** gene expression of pro-inflammatory cytokines(TNF-αand IL-6)was ***,the protein expressions of pro-inflammatory cytokines(TNF-αand IL-6)and estrogen receptors were ***:Marantodes pumilum *** crude aqueous extract and Dmcq B inhibited RANKL-stimulated osteoclast differentiation as evidenced by size reduction of giant multinucleated osteoclast cells,decreased TRACP 5b activity as well as the subsiding of resorbed pit area compared with normal *** addition,they reduced the gene and protein expressions of TNF-αand *** pumilum ***,Dmcq B,and estradiol treatments increased the protein expressions of estrogen receptors alpha and beta in ***:Marantodes pumilum *** and its active compound,Dmcq B can inhibit osteoclast differentiation.

关键词： Marantodes pumilum var.alata Phytoestrogen RAW264.7 induced-osteoclast Bone-resorbing effect

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Development of Immunosensor for Early Detection of Aquatic Harmful Algal Blooms （HABs）

引用

材料科学与工程（中英文B版） 2017年第3期7卷 127-134页

作者： Faridah Salam Hazana Razali Gayah Abdul Rahman Roziawati mohd Razali mohd nor azman Ayub Syah noor Muhamad Ramli norhafniza Awaludin Biotechnology and Nanotechnology Research Centre Malaysian Agricultural Research and Development Institute (MARDI) MARDI Headquarters Persiaran MARD1-UPM Serdang 43400 Selangor Malaysia Fisheries Research lnstitute(FRI) Batu Maung 11960 Penang Malaysia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comprehensive study of electronic polarizability and band gap of B_(2)O_(3)-Bi_(2)O_(3)-ZnO-SiO_(2)glass network

引用

Journal of Advanced Dielectrics 2017年第5期7卷 25-31页

作者： Iskandar Shahrim Mustafa Nur Ain Nabilah Razali Nurul Zahirah noor azman nor Zakiah Yahaya Muhammad Zulhafiz Mohamad Zaini Nur Lina Rusli Muhammad Bakhsh Nizamani Halimah Mohamed Kamari School of Physics University of Science Malaysia 11800 USMPulau PinangMalaysia Institute of Nano-optoelectronics Research University of Science Malaysia 11800 USM Pulau PinangMalaysia School of Distance Education University of Science Malaysia 11800 USM Pulau PinangMalaysia Science Faculty University Putra Malaysia 43400 SerdangSelangorMalaysia

Quaternary glasses were successfully fabricated using melt quenching technique based on the chemical compound composition(x)Bi_(2)O_(3)–(0:5-x)ZnO-(0.2)B_(2)O_(3)–(0.3)SiO_(2),where(x=0.1,0.2,0.3,0.4,0.45)*** sources of SiO_(2)was produced from rice husk ash(RHA)at 99.36%of SiO_(2).The Urbach energy was increased from 0.16 eV to the 0.29 eV as the mole of Bi_(2)O_(3)increased in the glass *** indirect energy band gap is indicated in decrement pattern with 3.15 eV towards 2.51 *** results of Urbach energy and band gap energy that were obtained are due to the increment of Bi^(3+)ion in the glass *** refractive indexes for the prepared glasses were evaluated at 2.36 to 2.54 based on the Lorentz–Lorentz formulation which correlated to the energy band *** calculated of molar polarizability,electronic polarizability and optical basicity exemplify fine complement to the Bi_(2)O_(3)addition in the glass *** glass sample was indicated in amorphous state.

关键词： Urbach energy energy band gap optical polarizability Lorentz-Lorentz X-ray powder diffraction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：