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Transactions of Nonferrous Metals Society of China 2018年第5期28卷 902-911页

作者： Ru MA yue LU Ling WANG Yi-nong WANG School of Materials Science and Engineering Dalian University of Technology Dalian 116024 China School of Materials and Metallurgy Northeastern University Shenyang 110819 China

Four different routes of asymmetric reduction rolling were conducted on AZ31 magnesium alloy to investigate their effect on the microstructure evolution and mechanical properties. Route A is the forward rolling; while during routes B and C the sheets are rotated 180o in rolling direction and normal direction, respectively; route D is the unidirectional rolling. The strain states of rolled sheets were analyzed by the finite element method, while the microstructure and texture were observed using optical microscopy, X-ray diffraction and electron back-scattered diffraction techniques, and the mechanical properties were measured by tensile test. The results show that route D produced the largest effective strain. Compared with other samples, sample D exhibited a homogeneous microstructure with fine grains as well as a weak and tilted texture, in corresponding, it performed excellent tensile properties, which suggested that route D was an effective way to enhance the strength and plasticity of AZ31 sheet.

关键词： AZ31 Mg alloy asymmetric reduction rolling rolling route fmite element analysis mechanical properties

Treatment of stellate ganglion block in diseases:Its role and application prospect

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World Journal of Clinical Cases 2023年第10期11卷 2160-2167页

作者： Jing-Jing Deng Cai-Ling Zhang Dian-Wen Liu Tao Huang Jian Xu Qing-Yan Liu yue-nong Zhang Department of Surgery and Anesthesia The Third Affiliated Hospital of Sun Yat-sen University Yuedong HospitalMeizhou 514700Guangdong ProvinceChina Department of Anesthesiology Meizhou Hospital of Traditional Chinese MedicineMeizhou 514700Guangdong ProvinceChina Department of Anesthesiology Shangqiu Maternal and Children Health Care HospitalShangqiu 476000Henan ProvinceChina Department of Anesthesiology Fengshun Hospital of Traditional Chinese MedicineMeizhou 514700Guangdong ProvinceChina

The stellate ganglion(SG),as a type of sympathetic ganglion,consists of the sixth and seventh cervical vertebrae and the first thoracic sympathetic *** block(SGB)is a minimally invasive injection that aims to inject low-concentration local anesthetics to induce a broad sympathetic blocking effect near the *** have been no changes and progress in the clinical application of SGB since the 1830s due to several potential risks,including hematoma from blood vessel injury,hoarseness from recurrent laryngeal nerve injury,and cardiopulmonary *** feasibility and safety of SGB have greatly improved since the appearance of ultrasound-guided *** recent years,SGB has been widely applied in the field of non-anesthesiology sedation,with significant therapeutic effects on pain,immunological diseases,somnipathy,psychological disorders,arrhythmias,and endocrine *** present study reviews the present application of SGB in clinical practice.

关键词： Echocardiography Pain Immunological diseases Somnipathy Psychological disorders Arrhythmias Endocrine diseases

Synthesis and Characterisation of Water-Soluble Carboxymethyl-Cyclodextrin Polymer as Capillary Electrophoresis Chiral Selector

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Chinese Chemical Letters 2000年第1期11卷 69-70页

作者： Xue Yan SHI Rui Fang FAN yue Qin ZHANG Jun Ling GU Ruo nong FU( College of Chemical Engineering and Material Science Beijing Institute of Technology, Beijing 100081) Coll. of Chem. Eng. and Mat. Science Beijing Institute of Technology Beijing 100081 China

The water-soluble carboxymethyl-cyclodextrin polymer (CM-CD polymer) was synthesized and used as capillary electrophoresis chiral selector. Verrapamil and thiopentorusodium were well separated using CM-CD polymer as c... 详细信息

关键词： Carboxymethyl-cyclodextrin polymer capillary electrophoresis chiral selector.

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CS/TPP纳米微胶囊的制备及其载药性能

高等学校化学学报 2009年第3期30卷 625-628页

作者：杨文静王婷何农跃东南大学生物电子学国家重点实验室南京210096

利用离子凝胶法,以三聚磷酸钠(TPP)为交联剂,由壳聚糖(CS)制备了CS/TPP纳米微胶囊.用红外光谱仪、扫描电镜和粒径分析仪进行了表征,并以牛血清蛋白(BSA)作为模型药物,考察了所制备的CS/TPP纳米微胶囊的包载和缓释性能.结果表明,CS/TPP... 详细信息

利用离子凝胶法,以三聚磷酸钠(TPP)为交联剂,由壳聚糖(CS)制备了CS/TPP纳米微胶囊.用红外光谱仪、扫描电镜和粒径分析仪进行了表征,并以牛血清蛋白(BSA)作为模型药物,考察了所制备的CS/TPP纳米微胶囊的包载和缓释性能.结果表明,CS/TPP纳米微胶囊的红外光谱相对于CS和TPP的红外光谱发生了很大变化,说明CS和TPP通过正负电荷吸引聚合成囊;粒径分析表明,离子凝胶法可以得到粒径约430 nm的均匀分散的壳聚糖纳米微胶囊,经冷冻干燥后粒径变为300 nm左右;微胶囊包封率最高可达79.74%,模型药物的持续释放时间可达7 d以上.

关键词：壳聚糖三聚磷酸钠药物缓释

相位角与肌少症及相关诊断指标的Meta分析

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中国组织工程研究 2025年第12期29卷 2575-2589页

作者：陈佳怡李惠菁农玉萱尹运芳刘小菠陈越胡笑燊钟冬灵李涓刘天宇金荣疆成都中医药大学养生康复学院四川省成都市610075 成都中医药大学临床医学院四川省成都市610075 成都顾连锦宸康复医院四川省成都市610000 成都中医药大学体育健康学院四川省成都市610075

目的:系统评价相位角与肌少症及相关诊断指标的相关性。方法:计算机检索PubMed、EMbase、Cochrane Library、Web of Science、中国知网、万方、维普和SinoMed数据库,收集关于相位角与肌少症及相关诊断指标相关的临床研究,检索时限均为... 详细信息

目的:系统评价相位角与肌少症及相关诊断指标的相关性。方法:计算机检索PubMed、EMbase、Cochrane Library、Web of Science、中国知网、万方、维普和SinoMed数据库,收集关于相位角与肌少症及相关诊断指标相关的临床研究,检索时限均为各数据库建库至2024-05-08。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险。采用RevMan 5.3和Stata 14.0软件进行Meta分析。结果:经筛选共纳入50篇合格文献。Meta分析结果显示,与非肌少症人群对比,肌少症患者的相位角显著降低[SMD=-0.99,95%CI(-1.09,-0.90),P<0.00001]。亚组分析结果表明,重度肌少症以及亚洲肌少症患者相位角差值更加显著,并且伴有肌少症的恶性肿瘤和呼吸系统疾病患者的相位角降低更加明显。相位角与骨骼肌质量指数(Pearson’s r=0.565,P<0.00001)、握力(Pearson’s r=0.446,P<0.00001)、步速(Pearson’s r=0.405,P<0.00001)均呈中等正相关,但与四肢骨骼肌质量指数呈极弱正相关(Pearson’s r=0.139,P=0.02)。结论:与非肌少症人群对比,相位角在肌少症人群具有显著差异性,且与肌少症诊断指标均存在不同程度相关性,提示相位角在肌少症的客观诊断中具有一定的临床价值,但其结果可能受到肌少症严重程度、相位角检测仪器等因素的影响,且因受纳入研究数量和质量的限制,上述结论尚待更多高质量研究予以验证。

关键词：肌少症相位角相关性 Meta分析生物电阻抗分析骨骼肌质量指数握力步速

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管道低频涡流探伤的仿真分析及试验研究

系统仿真学报 2007年第8期19卷 1686-1691页

作者：汪洋费跃农深圳大学机电与控制工程学院广东深圳518060

首先介绍了涡流检测基本原理以及电磁场问题的三维有限元算法,在此基础上,讲解了三维涡流场有限元仿真的具体方法和步骤,并对分析过程中的一些关键环节作了详细的说明;接着针对一些典型的缺陷,尤其是缺陷深度渐变的坑状缺陷,进行了细致... 详细信息

首先介绍了涡流检测基本原理以及电磁场问题的三维有限元算法,在此基础上,讲解了三维涡流场有限元仿真的具体方法和步骤,并对分析过程中的一些关键环节作了详细的说明;接着针对一些典型的缺陷,尤其是缺陷深度渐变的坑状缺陷,进行了细致的分析和比较,得出了相位差随缺陷变化的大致规律;最后结合具体试验检测结果,相互对比,说明了仿真的正确性,并进一步为缺陷特征的提取提供了理论依据。

关键词：涡流探伤有限元仿真相位差无损检测

Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-lnduced Inflammatory Reaction

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Chinese Medical Journal 2018年第14期131卷 1724-1731页

作者： Qiang Liu heng Zhao yue Gao Yan Meng Xiang-Xuan Zhao Shi-nong Pan Department of Radiology Shengjing Hospital China Medical University Shenyang Liaoning 110004 China Department of Radiology The First Affiliated Hospital of University of South China Hengyang Hunan 421001 China

Background： Dandelion is commonly used in traditional Chinese medicine with several active compounds found in extracts. It has a variety of pharmacological effects, such as a reduction in swelling and inflammation, and detoxification. The mechanism by which dandelion extract inhibits the inflammatory response in skeletal muscle cells remains unknown; therefore, the aim of this study was to investigate the effects of dandelion extract root on the proliferation of skeletal muscle cells and the alleviation of lipopolysaccharide （LPS）-induced inflammatory response in vitro. Methods： Rat skeletal muscle cells were isolated from Sprague-Dawley rat and cultured in vitro which were cultured in basal medium, or medium containing LPS or dandelion extract. Cell counting kit-8 （CCK-8） was employed to measure cell proliferation; meanwhile, the optimal concentration of dandelion extract and treatment time were selected. Crystal violet staining was used to detect the proliferation of muscle cells. Western blotting analysis was used to detect the levels of inflammatory factors, myogenic factor, and p-AKT protein expression. Results： The optimal concentration and treatment time of dandelion extract for the following study were 5 mg/ml and 4 days, respectively. Dandelion extract was found to increase proliferation of rat skeletal muscle cells （t = 3.145, P 〈 0.05）, with the highest effect observed at 5 mg/ml. LPS was found to decrease proliferation of skeletal muscle cells （t = -131.959, P 〈 0.001）, and dandelion extract could against this affection （t = 19.466, P 〈 0.01）. LPS could induce expression of inflammatory factors, including interleukin （IL）-16, IL-6 and tumor necrosis factor （TNF）-α （IL-16： t = 9.118, P 〈 0.01; IL-6： t = 4.346, P 〈 0.05; TNF-α： t = 15.806, P 〈 0.05）, and dandelion extract was shown to reduce LPS-induced expression of IL- 16, IL-6 and TNF-α （IL-I 6： t = -2.823, P 〈 0.05; IL-6： t = -3.348, P 〈 0.01; and TNF-α： t = -3.710, P 〈 0.01）. Furthermore, LPS was also

关键词： Anti-Inflammation Mechanism Dandelion Extract herbal Plant Inflammation Skeletal Muscle Cells

Experimental study on the oil production characteristics during the waterflooding of different types of reservoirs in Ordos Basin, NW China

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Petroleum Exploration and Development 2021年第4期48卷 935-945页

作者： XIAO Wenlian YANG Yubin LI Min LI nong YOU Jingxi ZHAO Jinzhou ZheNG Lingli ZHOU Kerning REN Jitian WANG yue State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu 610500China PetroChina Southwest Oil and Gas Field Branch Chengdu 610213China PetroChina Changqing Oilfield Company Xi'an 710018China

Waterflooding experiments were conducted in micro-models(microscopic scale)and on plunger cores from low permeability,extra-low permeability and ultra-low permeability reservoirs in the Ordos Basin under different displacement pressures using the NMR techniques to find out pore-scale oil occurrence state,oil production characteristics and residual oil distribution during the process of waterflooding and analyze the effect of pore structure and displacement pressure on waterflooding *** bound water condition,crude oil mainly occurs in medium and large pores in the low-permeability sample,while small pores and medium pores are the main distribution space of crude oil in extra-low permeability and ultra-low permeability *** the waterflooding,crude oil in the medium and large pores of the three types of samples are preferentially *** the decrease of permeability of the samples,the waterflooding front sequentially shows uniform displacement,network displacement and finger displacement,and correspondingly the oil recovery factors decrease *** waterflooding,the residual oil in low-permeability samples is mainly distributed in medium pores,and appears in membranous and angular dispersed phase;but that in the extra-low and ultra-low permeability samples is mainly distributed in small pores,and appears in continuous phase formed by a bypass flow and dispersed *** low-permeability samples have higher and stable oil displacement efficiency,while the oil displacement efficiency of the extra-low permeability and ultra-low permeability samples is lower,but increases to a certain extent with the increase of displacement pressure.

关键词： waterflooding characteristics oil occurrence state residual oil distribution NMR displacement efficiency Ordos Basin

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机载高波段SAR大斜视角大场景成像算法研究

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电子与信息学报 2008年第9期30卷 2046-2050页

作者：李悦丽梁甸农国防科技大学电子科学与工程学院长沙410073

该文基于合成孔径雷达(SAR)斜视成像模式,分析了机载成像处理中斜距展开和二维解耦合近似相位误差与波长、斜视角、分辨率和测绘带宽度等参数的关系,证明二阶近似可满足常规高波段SAR大斜视角成像要求,但改进RD算法的聚集深度问题限制... 详细信息

该文基于合成孔径雷达(SAR)斜视成像模式,分析了机载成像处理中斜距展开和二维解耦合近似相位误差与波长、斜视角、分辨率和测绘带宽度等参数的关系,证明二阶近似可满足常规高波段SAR大斜视角成像要求,但改进RD算法的聚集深度问题限制了成像方位孔径,常规CS算法未考虑二次距离压缩(SRC)的空变性,其大场景成像效果均不佳,只有NCS算法考虑了SRC随距离的线性变化,大场景高波段SAR成像聚焦性能最优。对毫米波SAR点目标成像的计算机仿真结果证明了上述分析结果。

关键词： SAR 大斜视角成像二维频域解耦合距离走动校正二次距离压缩非线性CS算法

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p16基因甲基化的芯片定量检测

高等学校化学学报 2005年第3期26卷 449-451页

作者：沈佳尧侯鹏祭美菊李松何农跃苏州大学生命科学学院苏州215007 东南大学生物科学与医学工程系吴健雄实验室南京210096

To quantitatively detect hypermethylation and to analyze methylation pattern, a methylation-specific oligonucleotide microarray for quantitative analysis was developed. The method used bisulfite-modified DNA as a template for PCR amplification, resulting in conversion of unmethylated cytosine, but not methylated cytosine, into thymine within CpG islands of interest. The amplified product, therefore, may contain a pool of DNA fragments with altered nucleotide sequences due to differential methylation status. A test sample was hybridized to a set of oligonucleotide arrays that discriminate methylated and unmethylated cytosine at specific nucleotide positions,and quantitative differences in hybridization were determined by fluorescence analysis. Four clinical samples of gastric cancer were quantitatively detected and methylation pattern of five methylated clones were analyzed with the methylation-specific oligonucleotide microarray. The results of microarray hybridization were in agreement with bisulfite genomic DNA sequencing. It showed that methylation-specific oligonucleotide microarray for quantitative analysis is a promising technique for mapping methylation changes in multiple CpG island loci and for generating epigenetic profiles in cancer.

关键词： DNA甲基化荧光强度标准曲线 p16基因甲基化检测型基因芯片