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Papillary Carcinoma on Stroma Ovarii: A Case Report from Madagascar and Review of the Literature

Journal of Cancer Therapy 2024年第3期15卷 57-61页

作者： Toky Rakotoarivo Christiana Ranaivoson Vonjy Andrianarison nomeharisoa rodrigue emile hasiniatsy Florine Rafaramino Department of Oncology University Hospital Tanambao Antsiranana Madagascar Department of Oncology University Hospital Joseph Ravoahangy Andrianavalona Antananarivo Madagascar Department of Radiotherapy University Hospital Joseph Ravoahangy Andrianavalona Antananarivo Madagascar Department of Oncology and Pallliative Care Soavinandriana Hospital Center Antananarivo Madagascar

A 64-year-old woman with no particular history presented with chronic pelvic pain since November 2021. The ultrasound performed showed multiple right ovarian cystic ranging from 0.4 to 4 cm on the long axis. She underwent a right salpingo-oophorectomy in May 2022. The anatomical pathology result is in favor of a papillary carcinoma developed on stroma ovarii. No adjuvant treatment was necessary since the tumor was well limited, without capsular rupture, stage IA. The thyroid test was normal. The patient is currently being monitored. There is no sign of recurrence 20 months after surgery.

关键词： Papillary Carcinoma Surgery Struma Ovarii

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Invasive Mole of the Uterus: A Case Report

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Open Journal of Pathology 2022年第4期12卷 177-182页

作者： Herilalao Elisabeth Razafindrafara Zo Irène Raivoherivony Joëlle Razafimahefa Vahatra nomeharisoa rodrigue emile hasiniatsy Romuald Randriamahavonjy Nantenaina Soa Randrianjafisamindrakotroka Department of Pathology Joseph Ravoahangy Andrianavalona University Hospital Antananarivo Madagascar

Invasive mole is a rare subgroup of gestational trophoblastic disease characterized by the invasion of molar tissue into the myometrium or uterine vasculature. In this paper, we report the third case of invasive mole described in the Malagasy literature. A 33-year-old woman was referred to the Soavinandriana Hospital, her complaint was persistent vaginal bleeding during 2 months, occurring at 3 months of pregnancy with biological anemia without hemodynamic repercussions. The human chorionic gonadotropin (HCG) level was 385,931 mIU/ml. A haemostasis hysterectomy was performed. Histological examination showed an enlarged uterus and endometrial cavity containing edematous chorionic villi with trophoblastic proliferation invading the myometrium. The diagnosis was an invasive mole, stage I, FIGO score 6. Chemotherapy was prescribed but was not honored. After 45 days of follow-up, the serum βHCG level decreased to 1803 mIU/ml, without clinical symptoms. The patient then lost sight. Persistent vaginal bleeding after pregnancy may be the only clinical symptom of an invasive mole and should raise suspicion. Histological examination establishes the diagnosis. As this is an unusual cause of vaginal bleeding, our case should remind physicians that when faced with this symptom, the possibility of an invasive mole should be considered in order to make an early diagnosis for less aggressive treatment.

关键词： Hydatiform Mole Gestational Trophoblastic Disease Invasive Mole Madagascar

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