检索结果-南通市图书馆

Advances in Computed Tomography 2013年第1期2卷 13-19页

作者： Edouard Cheneau Bruno Vahdat noemie resseguier Laurent Bernard Annamaria Molon Roch Giorgi Dimitri Panagides Service de Cardiologie Clinique BouchardMarseilleFrance Service de Sante Publique et d’Information Medicale Hopital de la TimoneMarseilleFrance

Purpose:When Coronary Computed Tomography (CCT) detects coronary obstruction, patients are regularly referred to invasive angiogram. With higher sensitivity than specificity, CCT might induce unnecessary angiograms (“false positive CCT”). We sought to determine the patients and CCT findings associated with false positive CCT. Methods: Patients were prospectively referred to CCT with a 64-slice CT scan for suspected CAD. Inclusion criteria were: 1) clinically suspected angina pectoris;or 2) suspected silent ischemia on resting EKG. Exclusion criteria were acute coronary syndrome and non sinus rhythm. Invasive coronary angiogram (ICA) was performed on the basis of CCT findings (stenosis >50%). Analysis was performed on a per patient basis. Results: Out of 702 patients, 228 had suspected significant stenosis by CCT and ICA was performed in 176 patients. Coronary stenosis >50% was not confirmed by ICA in 44 (25%). In multivariate analysis, we observed that atypical angina (OR 3.63,CI 1.43-9.66), silent ischemia (OR 5.11, CI 1.89-14.6) and number of suspected stenosed arteries by CCT (OR 1.81, CI 1.15-2.94) were independently predictive of false positive CCT (p Conclusions:Performing CCT for atypical angina or silent ischemia is associated with higher rate of unnecessary invasive coronary angiograms. We failed to identify lesions characteristics prone to be “false positive” of CCT.

关键词： Angina Coronary Disease Diagnosis CCT

Severe acute respiratory syndrome coronavirus-2-related and imputable deaths in children:results from the French pediatric national registry

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第6期20卷 611-620页

作者： Marguerite Lockhart-Bouron noemie Vanel Michael Levy Anais R.Briant Etienne Javouhey Sophie Breinig Julia Dina Marion Caseris Francois Angoulvant Stephane Leteurtre Morgan Recher David W.Brossier Univ.Lille CHU LilleULR 2694-METRICS:Evaluation Des Technologies de Sante Et Des Pratiques Medicales59000LilleFrance Pediatric Intensive Care Unit CHU de MarseilleMarseilleFrance Pediatric Intensive Care Unit CHU Robert-DebreAssistance Publique Hopitaux de ParisParisFrance UniversitéParis-Cite ParisFrance Biostatistics and Clinical Research Unit CHU de Caen Normandie14000CaenFrance Pediatric Intensive Care Hospices Civils de LyonLyonFrance Neonatal andPediatric IntensiveCare Unit Children's HospitalToulouseFrance Virology Department INSERM U1311 DynamicureUniv CAEN NormandieCHU de Caen14000 CaenFrance Medical School Universite Caen Normandie14000 CaenFrance Department of Pediatrics CHU Robert-DebréAssistance Publique Hopitaux de ParisParisFrance Department Women-Mother-Child Service of PediatricsLausanne University Hospital(CHUV)LausanneSwitzerland Pediatric Intensive Care Unit Réanimation Et Soins Intensifs PéediatriquesCHU de CAENAvenue de La Cote de Nacre14000 CaenFrance CHU Sainte Justine Research Center MontréalCanada

Background Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)is responsible for an important mortality rate *** aimed to evaluate the actual imputability of SARS-CoV-2 on the mortality rate associated with SARS-CoV-2-related illnesses in the pediatric intensive care unit(PICU).Secondary objectives were to identify risk factors for *** This national multicenter comparative study comprised all patients under 18 years old with positive SARS-CoV-2 polymerase chain reactions(PCRs)[acute corona virus disease 2019(COVID-19)or incidental SARS-CoV-2 infection]and/or pediatric inflammatory multisystem syndrome(PIMS)recorded in the French PICU registry(PICURe)between September 1,2021,and August 31,*** patients were classified and compared according to their living status at the end of their PICU *** patients were evaluated by four experts in the field of pediatric infectiology and/or pediatric intensive *** imputability of SARS-CoV-2 as the cause of death was classified into four categories:certain,very probable,possible,or unlikely,and was defined by any of the first three *** There were 948 patients included of which 43 died(4.5%).From this,26 deaths(67%)could be attributed to SARS-CoV-2 infection,with an overall mortality rate of 2.8%.The imputability of death to SARS-CoV-2 was considered certain in only one case(O.1%).Deceased patients suffered more often from comorbidities,especially heart disease,neurological disorders,hematological disease,cancer,and *** of the deceased patients were admitted for pediatric inflam-matory multisystem syndrome(PIMS).Mortality risk factors were male gender,cardiac comorbidities,cancer,and acute respiratorydistress *** SARS-CoV-2 mortality in the French pediatric population was *** though the imputability of SARS-Cov-2 on mortality was considered in almost two-thirds of cases,this imputability was considered certain in only one case.

关键词： Death Pediatric intensive care unit SARS-CoV-2

A chromosome-scale genome assembly of Rauvolfia tetraphylla facilitates identification of the complete ajmaline biosynthetic pathway

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Communications 2024年第4期5卷 129-132页

作者： Enzo Lezin Ines Carqueijeiro Clement Cuello Mickael Durand Hans JJansen Valentin Verges Caroline Birer Williams Audrey Oudin Thomas Duge de Bernonville Julien Petrignet noemie Celton Benoit St-Pierre Nicolas Papon Chao Sun Ron P.Dirks Sarah Ellen O’Connor Michael Krogh Jensen Sebastien Besseau Vincent Courdavault Biomole´cules et Biotechnologies Vegetales EA2106Universite´de Tours37200 ToursFrance Future Genomics Technologies 2333 BE Leidenthe Netherlands Laboratoire Synthe se et Isolement de Molecules BioActives(SIMBA EA 7502)Universitede Tours37200 ToursFrance Laboratoire de Cytoge´netique Constitutionnelle CHRU de Tours-Hopital Bretonneau37044 ToursFrance University Angers University BrestIRFSFR ICAT49000 AngersFrance Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 2800China Department of Natural Product Biosynthesis Max Planck Institute for Chemical Ecology07745 JenaGermany Novo Nordisk Foundation Center for Biosustainability Technical University of Denmark100193 Kgs LyngbyDenmark Present address:Limagrain Center de RechercheRoute d’EnnezatChappesFrance These authors contributed equally to this article

Dear Editor,Rauvolfia tetraphylla(aka the Devil pepper)(Supplemental Figure 1)is a well-known medicinal plant that produces monoterpenoid indole alkaloids(MIAs).This MIA biosynthesis occurs in several organs,including leaves,stems,fruit,and roots,which accumulate the famous antiarrhythmic ajmaline(Kumar et al.2016a,2016b;Kumara et al.,2019).MIAs are natural products notably involved in plant adaptation to the environment and defense against *** mainly results from their high biological activities,which also explain their pharmacological properties.

关键词： properties. Figure roots

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

白石画廊（首尔）

城市环境设计 2024年第1期 150-154页

作者：户部正俊 Wuijoon Ha noemie Robitaille

我们将首尔市中心绿意盎然的南山公园对面的商业设施改建成了艺术画廊。利用现有的跃层结构，将多变的展示空间延伸到整个建筑，创造出由白盒子的抽象性和现有建筑的复杂性碰撞而产生的动态艺术空间。现有的外立面被涂成黑色，通过将木...

我们将首尔市中心绿意盎然的南山公园对面的商业设施改建成了艺术画廊。利用现有的跃层结构，将多变的展示空间延伸到整个建筑，创造出由白盒子的抽象性和现有建筑的复杂性碰撞而产生的动态艺术空间。现有的外立面被涂成黑色，通过将木材和天空投射到玻璃表面上，消除了建筑本身的存在感，创造出一种引导性的空间体验，将观众的意识从城市的日常切换到白色抽象艺术空间。

关键词：

来源：博看期刊

Visual system repair:what's next?

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第4期17卷 800-802页

作者： noemie Vilallongue Homaira Nawabi Univ.Grenoble Alpes InsermGrenoble Institut NeurosciencesGrenobleFrance

One of the hallmarks of the mature neurons from the central nervous system(CNS)is their inability to grow their axons after an *** turn,whenever a neuronal circuit is damaged,either by a neurodegenerative disease or a traumatic injury,the motor and/or cognitive fu nctions associated with it are lost ***,understanding the molecular and cellular barriers to CNS repair is a major challenge not only for Neurosciences but also for public health.

关键词： traumatic whenever system

Axon guidance in regeneration of the mature central nervous system:step by step

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第12期18卷 2665-2666页

作者： Julia Schaeffer noemie Vilallongue Stephane Belin Homaira Nawabi Univ.Grenoble Alpes InsermU1216Grenoble Institut NeurosciencesGrenobleFrance

Unlocking axon regeneration in the injured central nervous system:In adult mammals,central nervous system(CNS)neurons fail to regenerate a?ter a lesion,whether it is traumatic–after spinal cord injury for example–or... 详细信息

关键词： traumatic system regeneration

在线全文

学校读者我要写书评

暂无评论

白石画廊（新加坡）

城市环境设计 2024年第1期147卷 138-141页

作者：户部正俊王婉璇望月杨平新田本

我们将这座面向新加坡港口的巨大仓库空间改造成为亚洲规模最大的画廊空间。白石画廊与同一大楼内的新加坡美术馆（SAM）一楼相连，在新加坡市中心创建了一个新的亚洲当代艺术中心。我们在接待区设计了一个像森林一样轮廓模糊的透明装...

我们将这座面向新加坡港口的巨大仓库空间改造成为亚洲规模最大的画廊空间。白石画廊与同一大楼内的新加坡美术馆（SAM）一楼相连，在新加坡市中心创建了一个新的亚洲当代艺术中心。我们在接待区设计了一个像森林一样轮廓模糊的透明装置，象征着新加坡丰富的自然资源。它提供了一条可以透过阳光的隧道，成为新加坡喧嚣都市与艺术世界之间的门槛。

关键词：

来源：博看期刊

A diagnostic protocol designed for determining allergic causes in patients with blood eosinophilia

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2017年第4期4卷 181-192页

作者： Jean-François Magnaval Guy Laurent noemie Gaudré Judith Fillaux Antoine Berry Department of Medical Parasitology Faculty of MedicineToulouse University37 aliees Jules-GuesdeToulouseFrance Purpan Center for Pathophysiology INSERM UMR Ulo43CNRS UMR S282Toulouse UniversityToulouseFrance Department of Hematology Toulouse University HospitalsToulouseFrance Cancer Institute Toulouse University and OncopoleToulouseFrance Department of Parasitology and Mycology Toulouse University HospitalsToulouseFrance PharmaDev IRD UMR 152Toulouse UniversityToulouseFrance

Background: Blood eosinophilia is a common laboratory abnormality, and its characterization frequently represents a quandary for primary care physicians. Consequently, in France, specialists and particularly hematologists, often must investigate patients who present with blood eosinophilia that often, but not always, occurs because of allergic causes. Both the Departments of Hematology and Parasitology at Toulouse University Hospitals established a collaboration to rule out allergic causes of eosinophilia, particularly helminthiases, prior to initiating more sophisticated ***: Since 2004, the authors employed the same protocol to investigate eosinophilic outpatients who attended the clinic of Parasitology at Toulouse University Hospitals, and they reported the performance of this diagnostic procedure that was designed to be rapid(no hospitalization required) and only moderately ***: A total of 406 patients who presented with blood eosinophilia greater than 0.5(×10~9, giga cells per litter, G/L) had an allergic etiology in 350(86.2%) cases. Among the remaining 56 subjects, 17 did not undergo a follow-up and 39 were referred to another specialized department, mostly Hematology. However, only 21 patients attended then were subsequently investigated. Non-allergic causes of eosinophilia, including 3 cases of the lymphoid variant of hypereosinophilic syndrome and 2 cases of myeloproliferative disorder, were identified in 14 patients, whereas 7 remained diagnosed as having idiopathic ***: This study underlines the need to investigate patients presenting with even moderate blood eosinophilia. The work-up that was employed appears to be efficient and versatile and may be used by any medical specialist, such as in hematology, infectious disease, or internal medicine departments, who needs to investigate eosinophilic patients and should initially rule out any etiology of allergic eosinophilia.

关键词： Blood eosinophilia Diagnostic protocol Classification Secondary eosinophilias Allergy Helminthiases

在线全文

学校读者我要写书评

暂无评论

“贫嘴” 夫妻的幸福生活

父母必读 2006年第11期 90-92页

作者： noemie Colomb

刚刚步入爱河时,你和老公说话的时候,都很注意推敲,希望对方听起来会很开心。但是,随着时间的推移,"三思而后说"渐渐变成了快言快语。养成了习惯,有时候话语就失去了控制……

关键词：幸福生活父母必读

The Alpine Seed Conservation and Research Network–a new initiative to conserve valuable plant species in the European Alps

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2017年第4期14卷 806-810页

作者： MULLER Jonas V BERG Christian DETRAZ-MEROZ Jacqueline ERSCHBAMER Brigitta FORT noemie LAMBELET-HAUETER Catherine MARGREITER Vera MOMBRIAL Florian MONDONI Andrea PAGITZ Konrad PORRO Francesco ROSSI Graziano SCHWAGER Patrick BREMAN Elinor Millennium Seed Bank Conservation ScienceRoyal Botanic Gardens KewWakehurst PlaceArdinglyWest Sussex RH17 6TNUnited Kingdom Karl-Franzens-Universitiit Graz Botanischer GartenHolteigasse 68010 GrazAustria Conservatoire et Jardin Botaniques de la Ville de Geneve Case Postale 60CH-1292 Chambesy(GE)Switzerland Institute of Botany University of Innsbruck Sternwartestrafle 156020 InnsbruckAustria Conservatoire botanique national alpin Domaine de Charanee05000 GapFrance Dipartimento di Scienze della Terra e dell'Ambiente Universita degli studi di PaviaVia S.Epifanio 14PaviaItaly

Safeguarding plants as seeds in ex situ collections is a cost effective element in an integrated plant conservation approach. The European Alps are a regional centre of plant diversity. Six institutions have established a regional network covering the European Alps which will conserve at least 500 priority plant species and which will improve the conservation status of plant species in grassland communities in the subalpine, alpine and nival altitudinal belts. Targeted research will expand the knowledge of the ecology of target speeies. Public engagement activities will raise the awareness for the importance of specific conservation actions in the European Alps.

关键词： Alpine Seed banks Ex situ conservation Plants Europe Natural grasslands Endemic species