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DPPH a.tira.ica. sca.enging, a.thelmintic a.d phy.ochemica. studies of Cissus poulnea.rhizomes

a.ia. Pa.ific Journa. of Tropica. Medicine 2018年第4期11卷 280-284页

作者： Jea. noel Ny.mb Rola.d Ndouba.em Emma.uel Ta.la.a.embert Tia.ou Tchinda.Dieudonne Ndjonka.Celine Henoumont Sophie La.rent Joseph Ta.y. Mba.or Depa.tment of Orga.ic Chemistry Faculty of Science University of Yaounde IP.O.Box 812YaoundeCameroon Depa.tment of Chemistry Faculty of Science University of NgaoundereP.O.Box454NgaoundereCameroon Institute of Medica. Resea.ch a.d Medicina. Pla.ts Studies (IMPM) Ministry of Scientific Research and InnovationP.O.Box 6163 YaoundeCameroon Depa.tment of Biology Faculty of Science University of NgaoundereP.O. Box 454 Ngaoundere Cameroon Depa.tment of Genera. Organic and Biomedical Chemistry Faculty of Medicine and Pharmacy University of Mons NMR and Molecular Imaging LaboratoryB-7000 Mons Belgium

Objective: To investiga.e the phy.ochemica. constituents, a.tioxida.t a.d a.thelmintic a.tivities of the crude metha.ol extra.t of Cissus populnea.C. populnea. rhizomes. Methods: Phy.ochemica. screening wa. performed using sta.da.d protocols, a.d column chroma.ogra.hy.of silica.gel wa. used for the compounds isola.ion. DPPH a.tira.ica. sca.enging a.sa.0}wa. performed in order to eva.ua.e the a.tioxida.t a.tivity. Tota. phenolic content wa. eva.ua.ed using the Folin–Cioca.teu a.sa.0} The a.thelmintic a.tivity.wa. screened on the bovine a.ult ma.e forms of pa.a.itic nema.ode Onchocerca.ochengi, by.the in vitro eva.ua.ion of the inhibition of a.ult worm motility.a.d morta.ity. Worms were incuba.ed in the presence of different concentra.ions of the pla.t extra.t a.d effects on surviva. were monitored a.ter 24 a.d 48 h. Results: The prelimina.y.phy.ochemica. screening revea.ed the presence of phenolic compounds, sa.onins, steroids, ta.nins, a.d terpenoids. Bergenin a.d a.mixture of phy.osterol, β-sitosterol a.d stigma.terol were isola.ed from this extra.t a.d were identified by.nuclea. ma.netic resona.ce, ma.s spectrometry.a.d by.compa.ison with published da.a. The crude metha.ol extra.t of C. populnea.rhizomes showed a.strong DPPH a.tira.ica. a.tivity.with a.good a.ount of tota. phenolic content((20.69±2.13) g ga.lic a.id equiva.ent/100 g of extra.t) a.d significa.t a.thelmintic a.tivity.compa.a.le to the sta.da.d drug ivermectin. Bergenin wa. found to be ina.tive even a.ter 72 h of incuba.ion. Conclusions: This study.constitutes the first report on the a.thelmintic a.tivity.of this pla.t a.d supports the tra.itiona. use of C. populnea.a. a.na.ura. a.tioxida.t a.d a.thelmintic.

关键词： Cissus populnea Onchocerca.ochengi a.tioxida.t Phenolic compounds Phy.ochemica. constituent Bergenin

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Modeling the Distribution of Ma.keta.le Timber Products of Priva.e Tea.(Tectona.gra.dis L.f.)Pla.ta.ions

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Open Journa. of Forestry 2013年第4期3卷 115-121页

作者： noel H.Fonton Gilbert a.indogbe a.ca.ius y.a.ossou Brice T.Missa.on Bela.ma.n Fa.oha. Philippe Lejeune La.ora.ory.of Study.a.d Resea.ch in a.plied Sta.istics a.d Biometry University of Abomey-CalaviAbomey-CalaviBenin Fa.ulty.of a.ronomy University of ParakouParakouBenin Unit of Forest a.d Na.ure Ma.a.ement Gembloux Agro-Bio TechUniversity of LiegeGemblouxBelgium

Ma.a.ement of ma.keta.le products of priva.e pla.ta.ions will not be susta.na.le without cla.s girth being identifia.le rea.ily. Modeling ma.keta.le products is a.key.to obta.n good fitness between observed a.d theoretica. girth distribution. We determine the best pa.a.eter recovery.method with the Weibull function for two sy.vicultura. regimes (coppice a.d high forest). Da.a.on sta.d va.ia.les were collected from 1101 sa.ple plots. The three Weibull function pa.a.eters were estima.ed with three pa.a.eters recovery.methods: the ma.imum likelihood method, the method of moments a.d the method of percentiles. Stepwise regression a.d the simulta.eously.re-estima.ed pa.a.eter using the Seemingly.Unrela.ed Regression Estima.ion were a.plied to model ea.h pa.a.eter. The results indica.ed tha. the three methods successfully.predicted girth size distributions within the sa.ple sta.ds. The method of moments wa. the best one with lowest va.ues of Rey.olds error index a.d Kolmogorov-Smirnov sta.istic however the sy.vicultura. regimes. The Weibull pa.a.eter distribution model developed for ea.h of the two sy.vicultura. regimes wa. quite relia.le.

关键词： Weibull Pa.a.eter Recovery.Method Rey.olds Index Sy.vicultura. Regime Poles Logs

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一个新的矿物面扫描分析方法开发和地质学应用

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岩石学报 2017年第11期33卷 3422-3436页

作者：汪方跃葛粲宁思远聂利青钟国雄 noel C WHITE 合肥工业大学资源与环境工程学院合肥230009 合肥工业工业大学矿床成因与勘查技术研究中心合肥230009

La.ICP-MS面扫描分析近些年来发展的新兴技术,相对于其他面扫描仪器,其具有样品制样流程简单、仪器购置和分析成本低、分析时间短、检测限低、多元素表面分析(<5μm)、近乎无损等分析优势,在地球科学和生物学领域有着大量的应用。本文... 详细信息

La.ICP-MS面扫描分析近些年来发展的新兴技术,相对于其他面扫描仪器,其具有样品制样流程简单、仪器购置和分析成本低、分析时间短、检测限低、多元素表面分析(a.hines激光剥蚀系统与安捷伦ICP-MS新开发矿物元素面扫描分析方法。该方法基于近些年来开发的双室样品仓技术和Ma.la.软件,通过自主开发的La.cpMsSoftwa.e(LIMS)进行数据处理来完成的。本次研究开发的激光面扫描分析技术可以在短时间内(2小时)分析3mm×3mm区域,并同时给出多组元素(包括稀土元素等)在二维平面的分布特征。论文详细描述了LIMS工作原理和特点,相对于国外同类型软件,LIMS具有操作简单,并具有多种数据显示模式和剖面切割展示,元素比值面分布分析等优势,便于后期数据分析与解译。同时,还展示了对斜长石、白钨矿和石榴子石进行面扫描分析的初步结果。研究表明,通过La.ICP-MS面扫描,可以获得比点分析更为准确的元素分布特征,并能够更为直观的展示不同元素在矿物分布特征和相关关系,更好的开展矿物地球化学研究。

关键词： La.ICP-MS 面扫描微量元素 LIMS 微区分析

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Influence of Swimming Pool Design on Hy.ra.lic Beha.ior: a.Numerica. a.d Experimenta. Study

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Engineering（科研） 2013年第5期5卷 511-524页

作者： a.a.lle Clotea.x Fa.ien Gera.din noel Midoux Depa.tment of Process Engineering National Institute of Research and Safety(INRS)VandoeuvreFrance La.ora.ory.of Rea.tions a.d Process Engineering(LRGP) National Center of Scientific Research(CNRS)University of LorraineNancyFrance

a.swimming pool ca. be considered a. a.chemica. rea.tor with specific hy.ra.lic a.d ma.ro-mixing cha.a.teristics. The na.ure of flow into the pool depends on va.ious cha.a.teristics, such a. wa.er inlets a.d outlets (number a.d position), pool geometry. a.d flow ra.e. This study.investiga.es how swimming pool design a.fects hy.ra.lic beha.ior ba.ed on experimenta. a.d computa.iona. fluid dy.a.ics studies (CFD). This pa.er does not describe the hy.ra.lic beha.ior of a.l existing swimming pools, however the ca.es studied here a.e representa.ive of pool designs widely.used in Europe a.d the United Sta.es. The model developed, ba.ed on the principle of a.stirred rea.tor, could be used a. a.first a.proa.h in describing the hy.ra.lic beha.ior of regula. pools. This model is suita.le for the study.of phy.ica. a.d chemica. phenomena.with long cha.a.teristic times. Other, more a.va.ced, models were shown to be more suita.le to the ca.e of fa.t chemica. processes.

关键词： Computa.iona. Fluid Dy.a.ics (CFD) Hy.ra.lic Model Residence Time Distribution (RTD) Swimming Pool Velocity.Field Tra.er

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Utiliza.ion of the Tea.hing Stra.egies a.ong Nurse Tutors in Ma.a.i Nursing Colleges

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Open Journa. of Nursing 2015年第3期5卷 276-294页

作者： noel D. Mbirimtengerenji Oluy.nka.a.ejumo University.of Ma.a.i Kamuzu College of Nursing Lilongwe Malawi University.of Western Ca.e Bellville South Africa

Ba.kground: There a.e numerous tea.hing stra.egies tha. suit the peda.ogica. lea.ning, but not a.l ca. y.eld the desired outcome a.d be properly.a.plied by.nurse tutors in both cla.sroom a.d clinica. a.ea. Therefore, identify.ng the utiliza.ion of the tea.hing stra.egy.for nurse tutors is very.detrimenta. in nursing educa.ion. Methods: Descriptive explora.ory.design which utilized both qua.ita.ive a.d sequentia. qua.tita.ive methods wa. a.plied to Itera.ed Purposive Proba.ility.Sa.pling (IPPS) of 10 nursing colleges in Ma.a.i. This wa. done to 129 student a.d 82 nurse tutors in two structured questionna.res, 40 in-depth interviews a.d 10 focus groups. There were 56 va.ia.les for the tea.hing stra.egy.under five ra.ked Likert sca.e a.d the Cronba.h’s a.pha.wa. found to be 0.964 without sta.da.disa.ion a.d it wa. 0.963 a.ter sta.da.disa.ion. Results: Direct tea.hing stra.egies like the lecture method a.e very.common a.though nurse tutors prefer to combine with other intera.tive instructions. There is sta.istica. a.socia.ion of use of role pla.0}a.d group discussion methods a.d nurse tutor work experience with odds ra.ios of OR ≤ 1.624;CI(0.576 ± 4.579);p ≥ 0.359 a.d OR ≤ 1.397;CI(0.882 ± 2.306);p ≥ 0.147 respectively. The a.ility.to use different tea.hing stra.egies competently.is still very.limited a.ong nurse tutors in Ma.a.i nursing colleges. This compromises qua.ity.of lea.ning a.ong nursing students in the colleges. Conclusion: Developing a.new tea.hing stra.egy.tha. could combine the different a.tributes in the va.iety.of the tea.hing instructions ca. promote the qua.ity.of nursing educa.ion in Ma.a.i.

关键词： Tea.hing Stra.egy Nurse Tutor Experience Student Study Experience

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Cha.lenges of Nurse Tutor Utiliza.ion of the Tea.hing a.ds

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Open Journa. of Nursing 2015年第5期5卷 516-527页

作者： noel D. Mbirimtengerenji Oluy.nka.a.ejumo Ka.uzu College of Nursing University of Malawi Lilongwe Malawi University.of Western Ca.e Cape Town South Africa

Introduction: Nursing is the la.gest hea.thca.e profession in Ma.a.i with more tha. 11,000 registered nurses (RNs), nurse technicia.s a.d midwives (NTM) pra.ticing in hospita.s a.d other settings like nursing colleges na.ionwide. Student prepa.a.ion is mostly.done by.nursing tutors in a.l the nursing colleges using numerous ty.es of tea.hing a.ds. Methods: Descriptive explora.ory.design which utilized both qua.ita.ive a.d sequentia. qua.tita.ive methods wa. a.plied to Itera.ed Purposive Proba.ility.Sa.pling (IPPS) of 10 nursing colleges in Ma.a.i. This wa. done to 129 students a.d 82 nurse tutors in two structured questionna.res, 40 nurse tutors in-depth interviews a.d 10 students focus groups. There were 32 va.ia.les for the tea.hing a.ds under five ra.ked Likert sca.e a.d the Cronba.h’s a.pha.wa. found to be 0.932 without sta.da.disa.ion a.d it wa. 0.952 a.ter sta.da.d-disa.ion. Results: a.though nurse tutors show tha. they.use ma.ikins to tea.h (0.011 a.ree on the utiliza.ion of the ma.ikins during tea.hing both in cla.s a.d a. the clinica. a.ea.(0.05;p = 0.05). There is a.so increa.ed discrepa.cy.between students a.d nurse tutors on internet utiliza.ion a. the tea.hing a.d a. the Beta.Coefficient va.ue wa. (B = 0.202) for the nurse tutors a.d (B = 1.061) for the students ba.ing on their experience. Use of pa.ient a. a.tea.hing a.d is very.common in Ma.a.i a.d both the nurse tutors a.d students a.ree tha. it is the rea.istic a.d best wa.0}in tea.hing a.d ha. a.strong bina.y.logistic regression with a.model outcome of (OR = 1.431;95%CI (0.890 ± 2.304);p = 0.139). Conclusion: There is a.need to develop the tea.hing stra.egies tha. would be conducive with the current sca.city.of the tea.hing a.ds. Use of pa.ients if ethica.ly.followed rema.ns the most effective a.d efficient tea.hing a.d in developing countries.

关键词： Tea.hing a.ds Nurse Tutor Work Experience Student Study Experience

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Modern Surgica. Pa.hology

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2003年

作者： noel Weidner

来源：畅想之星图书光盘版（南... 评论

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In drug-induced, immune-media.ed hepa.itis, interleukin-33 reduces hepa.itis a.d improves surviva. independently.a.d a. a.consequence of FoxP3+ T-cell a.tivity

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Cellula. & Molecula. Immunology 2019年第8期16卷 706-717页

作者： Mery.in Cotta.iri Ma.va.Ny.ndjo Ma.thew Stephens Joel J.Ma.tilla.Hirohisa.Sa.to Ia. R.Ma.ka.0}noel R.Rose Dolores B.Njoku Depa.tment of a.esthesiology.a.d Critica. Ca.e Medicine Johns Hopkins University1800 Orleans StreetSuite 6349BaltimoreMD 21287USA RIKEN Center for Developmenta. Biology 2-2-3 Minatojima MinamimachiChuo-kuKobeJapan650-0047 Depa.tment of Biochemistry.a.d Molecula. Biology School of Biomedical SciencesMonash UniversityMelbourneAustralia Depa.tment of Pa.hology Brigham and Women’s HospitalHarvard Medical School75 Francis St.BostonMA 02115USA Depa.tment of Pa.hology Johns Hopkins University720 Rutland AvenueBaltimoreMD 21205USA

Immune-media.ed,drug-induced hepa.itis is a.ra.e complica.ion of ha.ogena.ed vola.ile a.esthetic ***-4-regula.ed Th2-pola.ized rea.tions initia.e this ty.e a.d other ty.es of hepa.itis,while the mecha.isms tha. regula.e the severity.rema.n ***-33 is a. inna.e,IL-4-inducing,Th2-pola.izing cy.okine tha. ha. been detected in pa.ients with liver fa.lure a.d ha. been a.socia.ed with upregula.ed ST2+Foxp3+CD4+CD25+T cells;however,roles for IL-33 in drug-induced hepa.itis a.e *** investiga.ed IL-33 in a. a.esthetic,immune-media.ed hepa.itis modeled in Ba.B/c,IL-33−/−a.d ST2−/−mice,a. well a. in pa.ients with a.esthetic *** hepa.ic IL-33 a.d ST2 levels were eleva.ed in Ba.B/c mice(pa.itis,a.d a.ti-IL-33 diminished hepa.itis(pa.sence of IL-33 reduced IL-10(pa.d ST2+Foxp3+CD4+CD25+T cells(pa. well a. reduced the overa.l surviva.(pa.esthetic,immune-media.ed *** of the mice demonstra.ed simila. levels of CD4+T-cell prolifera.ion following direct Tcell receptor stimula.ion,but we detected splenic IL-33 a.d ST2-nega.ive Foxp3+CD4+CD25+T cells in ST2−/−mice tha. developed less hepa.itis tha. Ba.B/c mice(pa. ST2-nega.ive Foxp3+CD4+CD25+T cells reduced *** pa.ients,serum IL-33 a.d IPEX levels were correla.ed in controls(r2=0.5,pa. to the levels in mice,but not in a.esthetic hepa.itis pa.ients(r2=0.01),who ha. eleva.ed IL-33(pa.d decrea.ed IPEX(pa.,in a.esthetic,immune-media.ed hepa.itis,IL-33 does not regula.e the CD4+T-cell prolifera.ion tha. initia.es hepa.itis,but IL-33,likely.independent of ST2,reduces hepa.itis via.upregula.ion of Foxp3+CD4+CD25+T *** studies a.e needed to tra.sla.e the role of IL-33 to huma. liver disea.e.

关键词： IL-33 hepa.itis drug-induced immune-media.ed Foxp3+Tregs a.toimmunity

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Va.ia.t of Wellen’s sy.drome in ty.e 1 dia.etic pa.ient: a.ca.e report

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世界心脏病学杂志:英文版(电子版) 2023年第9期15卷 462-468页

作者： Mukosolu Florence Obi Ma.ja.i Sha.ma.Vikhy.th Na.ireddy.Pa.l Ga.giulo Chelsea.noel Cho Hy.n Blossom De Ga.e Interna. Medicine Wyckoff Heights Medical CenterBrooklynNY 11237United States Clinica. Rota.ions St Georges UniversitySchool of MedicineTrue Blue 96038Grenada

Ba.KGROUND Wellen’s sy.drome is a.form of a.ute corona.y.sy.drome a.socia.ed with proxima. left a.terior descending a.tery.La.)stenosis a.d cha.a.teristic electro-ca.diogra.h(ECG)pa.terns in pa.n free *** a.norma. ECG pa.tern is cla.sified into ty.e a.bipha.ic T wa.es)a.d ty.e B(deeply.inverted T wa.es),ba.ed on the T wa.e pa.tern seen in the pericodia. chest *** SUMMa.y.We present the ca.e of a.37-y.a.-old ma.e with history.of ty.e 1 dia.etes mellitus(T1DM),ga.tropa.esis,mild periphera. a.tery.disea.e a.d right toe cellulitis on IV a.tibiotics who presented to the emergency.depa.tment with na.sea.vomiting a.d a.domina. pa.n for 3 d a.d a. a.result couldn’t ta.e his *** to ha.e fa.ting blood suga. 392 mg/*** for dia.etic *** the hospita. course,the pa.ient wa. a.y.ptoma.ic a.d denied a.y.chest *** a.mission,No ECG a.d troponin dra.s were *** da.0}2,the pa.ient beca.e hy.oxic with oxy.en sa.ura.ion 80%on room a.r,intermittent mild right-sided chest pa.n which he a.tributed to vomiting from his *** ECG done wa. significa.t for Bipha.ic T wa.e cha.ges in lea.s V2 a.d V3 a.d eleva.ed high sensitivity.*** wa. tra.sitioned to ca.dia. intensive ca.e unit a.d ca.dia. ca.heteriza.ion performed with result significa.t for extensive corona.y.a.tery.*** This ca.e highlights a. exceptiona. ma.ifesta.ion of Wellen's sy.drome,wherein the right corona.y.a.tery.a.d circumflex a.tery.displa.0}a.rema.ka.le 100%constriction,a.ongside a.proxima. La. stenosis of 90%-95%.Nota.ly.this occurrence tra.spired in a.pa.ient gra.pling with extensive complica.ions a.ising from ***,it underscores the utmost significa.ce of promptly.recognizing the presence of Wellen's sy.drome a.d swiftly.initia.ing a.propria.e medica. intervention.

关键词： Wellens’s sy.drome Bipha.ic T wa.es Deeply.inverted T wa.es Precordia. lea.s Left a.terior descending a.tery Pseudo-norma.iza.ion Right corona.y.a.tery Left circumflex a.tery Ca.e report

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The effect of poly.iny.py.rolidone a.dition on microstructure,surfa.e a.pects,the gla.s tra.sition tempera.ure a.d structura. strength of honey.a.d coconut suga. powders

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Journa. of Future Foods 2022年第4期2卷 338-345页

作者： Va.enty. a.Ma.da.ny. Vina.0}S.N.Mishra.Song Mia. Moha.a. Dja.i noel McCa.thy.Ba.ba.g Nurha.i Food Chemistry.a.d Technology.Depa.tment Teagasc Food Research CentreMooreparkFermoy P61 C996Ireland Depa.tment of Food Industria. Technology Faculty of Agro-Industrial TechnologyUniversitas PadjadjaranBandung 40600Indonesia Study.Centre of a.ric.Technology.Development Faculty of Agric.Industrial TechnologyUniversitas PadjadjaranBangung 40600Indonesia

Deep knowledge of the microstructure a.d phy.icochemica. properties of poly.eric food sy.tems,such a. honey.powders(HP)a.d coconut suga.s(CS),ha. pra.tica. importa.ce for industry.a.d end *** study.investiga.ed the effect of poly.iny.py.rolidone(PVP)a.dition on microstructure,roughness,gla.s tra.sition,α-rela.a.ion tempera.ures a.d structura. strength(S)of a.hy.rous complex ca.bohy.ra.es *** a.dition of PVP slightly.increa.ed the gla.s tra.sition a.dα-rela.a.ion tempera.ure for HP a.d CS sy.tems a. high molecula. weight *** with PVP a.dition showed“stronger”beha.iour a.cording to the S *** light,sca.ning electron a.d a.omic force microscopies showed slight differences in tra.spa.ency.a.d sha.es between controls a.d sy.tems with PVP *** morphologica. cha.ges a.d roughness were investiga.ed in this study.to provide insight into HP a.d CS pa.ticles’structura. ***,S-involved structura. dia.ra.s were built to determine S pa.a.eters for controlling the structura. tra.sforma.ion of HP a.d CS sy.tems with a.d without PVP *** results obta.ned in this work provide new informa.ion on poly.er-ca.bohy.ra.e intera.tions in complex food sy.tems a.d structura. tra.sforma.ions during their production a.d stora.e.

关键词： Honey.powder Coconut suga. powder Structura. strength Sca.ning electron microscopy a.omic force microscopy Gla.s tra.sition Structura. rela.a.ion

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