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World Journal of Gastrointestinal Endoscopy 2011年第4期3卷 71-77页

作者： Shotaro Enomoto Masashi Oka Hiroshi Ohata Chizu Mukoubayashi Mika Watanabe Kosaku Moribata Yosuke Muraki Naoki Shingaki Hisanobu Deguchi Kazuki Ueda Izumi Inoue Takao Maekita Mikitaka Iguchi Kimihiko Yanaoka Hideyuki tamai Mitsuhiro Fujishiro Osamu Mohara Masao Ichinose Second Department of Internal Medicine Wakayama Medical UniversityWakayama641-0012Japan Wakayama Wellness Foundation Wakayama640-8404Japan Department of Endoscopy and Endoscopic Surgery Faculty of MedicineUniversity of TokyoTokyo113-8655Japan

AIM:To evaluate the association of Helicobacter pylori(***)-related chronic gastritis stage with upper gastro-intestinal symptoms and gastro-eso-phageal reflux disease(GERD).METHODS:Subjects underwent upper gastrointestinal endoscopy,a questionnaire using a frequency scale for symptoms of GERD(FSSG),and measurements of serum ***-antibody and pepsinogen(PG)*** were classified into the following 4 groups in terms of ***-related chronic gastritis stage:Group A(n = 219),***(-)PG(-);Group B(n = 310),***(+)PG(-);Group C(n = 279),***(+)PG(+);and Group D(n = 17),***(-)PG(+).RESULTS:Reflux esophagitis occurred in 30.6% of Group A,14.5% of Group B,6.8% of Group C,and 0% of Group D(P < 0.001).Scores for acid reflux sympto-ms decreased significantly with chro-nic gastritis stage(from Group A to D)(P < 0.05),while scores for dysmotility symptoms did no-t differ *** prevalence of nonerosive reflux disease(NERD)did not differ amo-ng ***,in subjects with GERD,the prevalence of NERD tended to increase with chronic gastritis stage(P = 0.081).CONCLUSION:Acid reflux sympto-ms and the prevalen-ce of reflux esophagitis can be assessed by measuring both serum ***-antibody and PG levels.

关键词： Gastro-eso-phageal reflux disease Helicobacter pylori Pepsinogen Screening and diagnosis

冠状动脉内超声检查在冠状动脉斑块旋切术中的应用

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湖南医科大学学报 1999年第6期24卷 556-558页

作者：李传昶玉井秀男许永胜日本国滋贺县立成人病中心循环器科附属湘雅医院心内科长沙410008

将冠状动脉内超声检查(ICUS检查) 应用于冠状动脉斑块旋切术(DCA) 中,32 例冠心病患者手术均获成功。平均冠状动脉内径由术前1-06 mm 增加至术后3-59 mm ,术后残留狭窄均小于25 % ,无1 例发生冠状动脉穿孔、破裂等严重并发症。在DCA 中... 详细信息

将冠状动脉内超声检查(ICUS检查) 应用于冠状动脉斑块旋切术(DCA) 中,32 例冠心病患者手术均获成功。平均冠状动脉内径由术前1-06 mm 增加至术后3-59 mm ,术后残留狭窄均小于25 % ,无1 例发生冠状动脉穿孔、破裂等严重并发症。在DCA 中,应用ICUS 可提高DCA 的疗效与成功率。

关键词：冠状动脉疾病超声波检查 ICUS DCA

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麦角新碱激发试验诊断变异型心绞痛

湖南医科大学学报 2000年第1期25卷 93-94页

作者：李传昶玉井秀男许永胜湖南医科大学附属湘雅医院心内科长沙410008 滋贺县立成病中心循环器科

随着心血管疾病介入诊断技术的不断发展与普及,选择性冠状动脉造影已经成为冠心病诊断的'金标准'.但发作性痉挛所引起的变异型心绞痛仍是常规冠脉造影的'盲点'.笔者采用静脉注射麦角新碱激发冠状动脉痉挛的方法诊断变异型心绞痛,获得满... 详细信息

随着心血管疾病介入诊断技术的不断发展与普及,选择性冠状动脉造影已经成为冠心病诊断的'金标准'.但发作性痉挛所引起的变异型心绞痛仍是常规冠脉造影的'盲点'.笔者采用静脉注射麦角新碱激发冠状动脉痉挛的方法诊断变异型心绞痛,获得满意效果,现报告如下.

关键词：麦角新碱心绞痛变异性激发试验

The Association of Autism Spectrum Disorders and Symptoms of Asthma, Allergic Rhinoconjunctivitis and Eczema among Japanese Children Aged 3 - 6 Years

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Health 2017年第8期9卷 1235-1250页

作者： Daisuke Hori Hiromasa Tsujiguchi Yasuhiro Kambayashi Toshio Hamagishi Masami Kitaoka Junko Mitoma Hiroki Asakura Fumihiko Suzuki Enoch Olando Anyenda Nguyen Thi Thu Thao Yohei Yamada Satoko tamai Koichiro Hayashi Yuri Hibino Aki Shibata Takiko Sagara Shinichiro Sasahara Ichiyo Matsuzaki Hiroyuki Nakamura Department of Environmental and Preventive Medicine Graduate School of Medical Science Kanazawa University Kanazawa Japan Faculty of Medicine University of Tsukuba Tsukuba Japan International Institute for Integrative Sleep Medicine University of Tsukuba Tsukuba Japan

There is insufficient epidemiological evidence on the relationship between autism spectrum disorder (ASD) and allergic diseases. We performed a cross-sectional survey to elucidate the associations between them using validated screening tools. The participants were children aged 3 - 6 years attending kindergarten or nursery school in Shika Town, Japan (n = 417;valid response rate = 80.4%). Autism spectrum features were scored on the Social Communication Questionnaire (SCQ). Allergic symptoms (asthma, allergic rhinoconjunctivitis, and eczema) were determined according to the criteria of the International Study of Asthma and Allergies in Childhood. A total of 15 children (4.5%) had an SCQ score of 11 points or higher. The prevalence of symptoms was 14.7% for asthma, and 5.3% for allergic rhinoconjunctivitis, and 11.4% for eczema. Logistic regression indicated that symptoms of eczema were significantly associated with SCQ scores of 11 points or higher [odds ratio (OR), 4.38;95% confidence interval (CI), 1.41 - 13.59]. The association persisted after adjustment for age, sex, and BMI (OR, 3.84;95% CI, 1.20 - 12.24). Moreover, asthmatic symptoms were significantly associated with male sex (OR, 2.09;95% CI, 1.12 - 3.92) and overweight status (OR, 2.45;95% CI, 1.03 - 5.83). This suggests that higher SCQ scores, which imply more autism spectrum features, are associated with higher prevalence of eczema symptoms. While no causal relationships can be made, ASD might be associated with eczema.

关键词： Asthma Autism Spectrum Disorder Eczema Early Screening Social Communication Questionnaire

Erratum to: Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure

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Nano Research 2022年第5期15卷 4773-4773页

作者： Tsukasa Akasaka Miho tamai Yoshitaka Yoshimura Natsumi Ushijima Shinichiro Numamoto Atsuro Yokoyama Hirofumi Miyaji Ryo Takata Shuichi Yamagata Yoshiaki Sato Ko Nakanishi Yasuhiro Yoshida Department of Biomaterials and Bioengineering Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Immune Signal Unit Okinawa Institute of Science and Technology Graduate UniversityOkinawa 904-0495Japan Department of Pharmacology Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Support Section for Education and Research Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Oral Functional Prosthodontics Division of Oral Functional ScienceFaculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Periodontology and Endodontology Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Orthodontics Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan

The article“Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure”,written by Tsukasa Akasaka,Miho tamai,Yoshitaka Yoshimura,Natsumi Ushijima,Shinichiro Numamoto,Atsuro Yokoyama,Hirofumi Miyaji,Ryo Takata,Shuichi Yamagata,Yoshiaki Sato,Ko Nakanishi,and Yasuhiro Yoshida,was originally published electronically on the publisher’s internet portal on January 17,2022 without open access.

关键词： internet portal Nat

太岳山油松基因保护林的研究(Ⅰ)——林分组成与结构的研究

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北京林业大学学报 2000年第4期22卷 35-39页

作者：韩海荣马钦彦中山典和玉井重信张宏达骈铁虎北京林业大学资源与环境学院北京100083 鸟取大学干旱地研究中心山西太岳山森林经营局山西046505

该文依据山西太岳林区油松基因保护林的外业调查材料 ,对该林分的组成和结构做了初步分析 .调查地的植物种类丰富 ,其中木本植物种类约占太岳林区的 1 5 .5 % ;枯死木以小径级木为主 .油松保护林是在 6 0～ 70a前 ,受某种干扰后形成的... 详细信息

该文依据山西太岳林区油松基因保护林的外业调查材料 ,对该林分的组成和结构做了初步分析 .调查地的植物种类丰富 ,其中木本植物种类约占太岳林区的 1 5 .5 % ;枯死木以小径级木为主 .油松保护林是在 6 0～ 70a前 ,受某种干扰后形成的相对同龄次生林 .大约在 40～ 5 0年生时 ,出现过一次小的干扰 .由于密度过大 ,油松的形状比 (H/D)值偏高 .更新层中 ,油松幼苗集中在林隙中 ;而辽东栎幼苗均匀分布在调查地中 ,但不能成为更替层 .说明两树种在幼苗阶段对光的要求不同 ,油松幼苗喜光 ;辽东栎幼苗较耐荫 ,但在一定年龄之后必须有足够的光照 .

关键词：油松保护林林分结构更新层基因保护林

N-钙黏素融合蛋白抑制P19分化伴随的细胞凋亡

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军医进修学院学报 2008年第1期29卷 48-50页

作者：岳晓珊玉井俊行長岡正人村上裕太赤池敏宏王钊清华大学医学院中药研究室中国北京100084 东京工业大学生体分子机能工学专攻日本横滨2268501

目的:讨论N-钙黏素融合蛋白N-cad-Fc对P19细胞分化过程中伴随的细胞凋亡的影响。方法:分子生物学技术制作N-钙黏素融合蛋白N-cad-Fc。视黄酸(retinoic acid,RA)诱导P19细胞分化,培养于明胶(gelatin)包被培养板上的P19细胞为对照组,普通... 详细信息

目的:讨论N-钙黏素融合蛋白N-cad-Fc对P19细胞分化过程中伴随的细胞凋亡的影响。方法:分子生物学技术制作N-钙黏素融合蛋白N-cad-Fc。视黄酸(retinoic acid,RA)诱导P19细胞分化,培养于明胶(gelatin)包被培养板上的P19细胞为对照组,普通光学显微镜观察其神经分化情况,TURNEL法和DNA片段化分析法检测细胞凋亡情况,alamarBlueTM染色法检测细胞存活情况。结果:培养于N-cad-Fc包被培养板上的P19细胞经RA诱导分化后细胞形态与明胶包被培养板上P19细胞分化形态一致,但分化过程中伴随的凋亡现象被明显抑制,分化诱导后细胞的存活率大大提高。结论:使用N-cad-Fc融合蛋白培养技术可以在不影响细胞分化状态的前提下降低分化过程中细胞的死亡率,为开发低死亡率的高效细胞分化诱导方法创造了条件。

关键词：细胞分化细胞凋亡 N-钙黏素

继发于颅内脑膜瘤动脉栓塞后的睫状视网膜动脉阻塞

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世界核心医学期刊文摘（眼科学分册） 2006年第10期2卷 33-33页

作者： Kunikata H. tamai M. 韩静 Department of Ophthalmology and Visual Science Tohoku University Graduate School of Medicine1-1 Seiryo-machiAoba-kuSendai 980-8574Japan

Purpose:To report a case in which a prophylactic embolization of a feeder artery to an intarcranial meningioma led to an occlusion of a cilioretinal ***:A case ***:A 48-year-old man with an intracranial meningioma presented with ocular pain and visual loss in his right eye following embolization of a feeder artery to the meningioma with polyvinyl ***:Ophthalmoscopy 1 month later showed a cilioretinal artery occlusion which was confirmed by fluorescein *** visual acuity was 0.01 in the right *** patient was not treated for his ocular symptoms,and his visual acuity 9 month postoperatively improved slightly to ***:Our case demonstrated that an occlusion of a retinal artery can be a complication of preoperative embolization of an artery to an intracranial tumor and can lead to severe visual loss.

关键词：睫状视网膜动脉颅内脑膜瘤动脉栓塞视网膜动脉阻塞右眼视力滋养动脉眼底造影预防性栓塞荧光

1个日本家族中与HPRP3基因中Thr494Met突变相关的常染色体显性色素性视网膜炎的临床特征

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世界核心医学期刊文摘（眼科学分册） 2005年第4期1卷 35-35页

作者： Itabashi T. Sato H. tamai M. 王媛

Purpose: To determine the clinical features of a Japanese family with autosomal dominant retinitis pigmentosa (ADRP) associated with a Thr494Met mutation in the HPRP3 gene. Methods: Mutational screening by direct sequencing was performed on 96 unrelated patients with ADRP. The clinical features were determined by visual acuity, slit- lamp biomicroscopy, electroretinography, fluorescein angiography, and kinetic visual field testing. Results: A Thr494Met mutation in the HPRP3 gene was found in one family and it cosegregated with ADRP in the three affected members. The ophthalmic findings were those of typical retinitis pigmentosa with rapid progression after 40- years- of- age. One patient also had retinoblastoma as a child. Conclusion: We conclude that the Thr494Met m utation in the HPRP3 gene causes ADRP in Japanese patients. This mutation was found in 1% of patients with ADRP in Japan.

关键词：视网膜炎色素性 HPRP3 Thr494Met 常染色体基因突变动态视野检查视网膜电描记法荧光素视网膜母细胞瘤

Progress in Physics and Technology Developments for the Modification of JT-60

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Plasma Science and Technology 2004年第1期6卷 2141-2150页

作者： H.tamai M.Matsukawa G.Kurita N.Hayashi K.Urata Y.M.Miura K.Kizu K.Tsuchiya A.Morioka Y.Kudo S.Sakurai K.Masaki T.Suzuki M.Takechi Y.Kamada A.Sakasai S.Ishida K.Abe A.Ando T.Cho T.Fujii T.Fujita S.Goto K.Hananda A.Hatayama T.Hino H.Horiike N.Hosogane M.Ichimura Tsuji-Iio S.Itoh M.Katsurai M.Kikuchi A.Kohyama H.Kubo M.Kuriyama M.Matsuoka Y.Miura N.Miya T.Mizuuchi K.Nagasaki H.Ninomiya N.Nishino Y.Ogawa K.Okano T.Ozeki M.Saigusa M.Sakamoto M.Satoh M.Shimada R.Shimada M.Shimizu T.Takagi Y.Takase T.Tanabe K.Toi Y.Ueda Y.Uesugi K.Ushigusa Y.Yagi T.Yamamoto K.Yatsu K.Yoshikawa Japan Atomic Energy Research Institute Naka Ibarahi 311-0193 Japan Tohoku University University of Tsukuba Osaka University Kyushu University Keio University Hokkaido University Tokyo Institute of Technology the University of Tokyo Kyoto University Mie University Hiroshima University Central research Institute of Electric Power Industry Ibaraki University ITER JCT Nagoya University National Institute for Fusion Science Kanazawa University National Institute of Advanced Industrial Science and Technology

Recent progress in the physics and engineering design study for themodification programme of JT-60 is presented. In order to achieve a steady state high-βplasmaoperation, which is the dominant issue of this programme, physics design for the MHD control and thestability analysis is investigated. Engineering design and the R & D for the superconducting coils,irradiation shield are performed well towards the mission of programme.

关键词： modification of JT-60 physics design technology developments