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International Journal of Organic Chemistry 2017年第2期7卷 153-170页

作者： Minako Oshima Minoru Matsuno tsutsumi Yuki Sunaga Nobumitsu Tomoyuki Haraguchi Takashiro Akitsu Department of Chemistry Faculty of Science Tokyo University of Science Tokyo Japan

We have prepared supramolecular systems of chiral Schiff base Ni(II), Cu(II), Zn(II) complexes and colloidal gold nanoparticles (AuNP) of 10 nm diameters. They demonstrated that direct adsorption of chiral Schiff base metal complex on the surface of AuNP owing to observation of clear induced CD spectra for the first time. We observed and discussed induced CD bands on AuNP from chiral Schiff base Ni(II), Cu(II), Zn(II) complexes.

关键词： Chiral Schiff Base Metal Complex Gold Nanoparticle

Metabolites from Resistant and Susceptible <i>Pinus thunbergii</i>after Inoculation with Pine Wood Nematode

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American Journal of Plant Sciences 2013年第3期4卷 512-518页

作者： Fujia Zhang Junko Kajiwara Yasuhiro Mori Mineko Ohira Yuji tsutsumi Ryuichiro Kondo Department of Forest and Forest Products Sciences Faculty of Agriculture Kyushu University Fukuoka Japan Forest Tree Breeding Center Forestry and Forest Products Research Institute Ibaraki Japan. Fukuoka Prefecture Forest Research and Extension Center Kurume Japan

Pine wilt disease (PWD), which is caused by pine wood nematodes (PWN), is one of the most serious forest diseases worldwide. To clarify the mechanism of resistance to PWD, we compared metabolites from resistant and susceptible Japanese black pine (Pinus thunbergii) families after inoculation with PWN. After 2 weeks to 1 month post inoculation, the number of PWN dramatically increased in susceptible plants, but not in resistant plants. At this PWN-proliferation phase, ethyl acetate soluble fractions extracted from PWN-inoculated plants were analyzed by gas chromatogramphy-mass spectrometry (GC-MS). Although most compounds were qualitatively and quantitatively similar between resistant and susceptible plants, resistant plants accumulated 2.0-fold more linoleic acid (LA) than susceptible plants. On the other hand, benzoic acid (BA) was barely detected in resistant plants, but it accumulated in susceptible plants as the number of PWN increased. Susceptible plants contained greater levels of the nematicidal compounds pinosylvin and pinosylvin monomethyl ether, compared with resistant plants. These results suggested that LA is involved in the resistance reaction against PWN-proliferation, and that BA could be a good biomarker for PWD.

关键词： Benzoic Acid Bursaphelenchus xylophilus Linoleic Acid Pinosylvin Pinus thunbergii Resistance

A NEW CHANNEL ASSIGNMENT METHOD FOR DEMAND ASSIGNMENT MULTICARRIER TDMA SATELLITE COMMUNICATION SYSTEMS

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A NEW CHANNEL ASSIGNMENT METHOD FOR DEMAND ASSIGNMENT MULTIC...

Cervical Nontuberculous Mycobacterial Lymphadenitis Mimicking a Thyroid Tumor and Infiltrating Deep into the Neck

International Conference on Communication Technology(ICCT’94)

作者： nobuhisa Kataoka Makoto Miyake Tadashi Fujino Osamu Yamanaka Keiji Okumura Junko Maruhashi Commun.Sys.Lab. Mitsubishi Electric Corp.Ofuna 5-1-1Kamakura-shi247 Japan Commun.Equip.Works Mitsubishi Electric Corp.Tsukaguchi-Honmachi 8-1-1Amagasaki-shi661 Japan

＜正＞A new practical method for channel assignment is proposed for demand assignment multicarrier TDMA satellite communication *** method enables us to markedly reduce the effect of "burst overlapping" without introducing the channel reassignment processing,and provides an excellent performance of blocking probability.

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Surgical Science 2012年第12期3卷 561-563页

作者： Kazuhiro Mino Tadao Okada Shouhei Honda Hisayuki Miyagi nobuhisa Ishiguro Kanako C. Kubota Taketomi Akinobu Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan Department of Pediatrics Hokkaido University Graduate School of Medicine Sapporo Japan Department of Surgical Pathology Hokkaido University Hospital Sapporo Japan

Aim: Nontuberculous Mycobacterial Lymphadenitis (NML), which occurs in 1.2 per 100,000 children, is very rare. And those which emerge at the anterior cervical portion and infiltrate deep into the neck are even more rare. Generally, this disorder is uncommon existed near the thyroid gland. We report here a case of NML mimicking a thyroid tumor and infiltrating into the deep part of the anterior neck. Case: A mass at the anterior portion of her neck was found at 5 years old. It was not mobile and palpated as an irregularly surfaced hard mass whose size was 3 cm at the anterior lower portion of her neck. Ultrasonography showed an oval mass which existed near the slightly inferior part of the right lobe of the thyroid gland. Enhanced computed tomography showed a mass near the slightly inferior part of the right lobe of the thyroid gland. The mass was resected with the platysma and the right sternohyoid muscle. In the HE staining, epithelioid cell and Langhans type giant cells surrounding coagulative necrosis lesions which seemed to be caseation necrosis existed, similarly to cervical NML. Discussion: No consensus exists for the treatment of NML, but many documents advise complete excision. When the lesion cannot be completely removed, excision as far as possible and additional antibiotics are recommended. The characteristics of imaging of NML around the thyroid gland and infiltrating deep into the anterior neck and mediastinum are discussed.

关键词： Anterior Cervical Portion Mediastinum Nontuberculous Mycobacterial lymphadenitis Thyroid Gland

Evaluation of Steel Reinforcing Bar in Concrete Using Electromagnetic Method

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Evaluation of Steel Reinforcing Bar in Concrete Using Electr...

Cell Proliferation Inhibition by Sericin from the Wild Silkworm, Cricula trifenestrata

2018远东无损检测新技术论坛

作者： Dongfeng HE Mitsuharu SHIWA Satoshi TAKAYA Naoto tsutsumi Koichi TSUCHIYA National Institute for Materials Science

We developed electromagnetic methods to evaluate the steel reinforcing bar in concrete. Using two probes and lower excitation frequencies of 3.8 k Hz and 4.2 k Hz, the depth and the diameter of the steel reinforcing bar can be evaluated and the resolution of better than 1 mm is obtained. Using higher excitation frequency of about 80 kHz, the corrosion of the steel reinforcing bar can be evaluated.

关键词： steel reinforcing bar electromagnetic method concrete corrosion

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Advances in Biological Chemistry 2016年第1期6卷 28-33页

作者： Wenqi Liu Mayumi Karimazawa Taku Ozaki Ying An Masao Miyazaki Koichi Suzuki Ken-ichi tsutsumi Tetsuro Yamashita United Graduate School of Agricultural Sciences Iwate University Morioka Japan Office of Research Exchange Iwate University Morioka Japan Research Center for Child Mental Development Hirosaki University Graduate School of Medicine Hirosaki Japan

Sericin is a major silk protein, and recent studies have shown that sericin has numerous physiological activities against cultured cells. For example, it accelerates mammalian cell proliferation and protects insect cells against cell death. In this study, we examined the activities of sericin prepared from the wild silkworm, Cricula trifenestrata. The results presented here indicated that C. trifenestrata sericin has anti-proliferative activity against feline kidney cells, while sericin from Bombyx mori promoted cell proliferation. The components of the sericin preparation that played a role in inhibition of proliferation were analyzed by fractionation through partition chromatography (Folch method) and reversed-phase chromatography. Our analysis showed that at least two components in the C. trifenestrata sericin preparation promoted the anti-proliferative activity in an additive or even synergistic manner. Therefore, differences in components between insect species may contribute to different activities against cultured cells.

关键词： Sericin Wild Silkworm Cell Death Anti-Proliferative Activity

与锡化合物偶联的溶聚SBR的结构和动态性能

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橡胶参考资料 1991年第9期21卷 49-56页

作者： F.tsutsumi 邹萍

序言人们希望轮胎具有滚动阻力低和抗湿滑性能高的特点。滚动阻力主要是由于胎面的滞后作用造成。大多数胎面胶含有SBR、NR和BR。标准的冷乳聚SBR(23％苯乙烯)能赋予硫化胶较好的抗湿滑性能,但是滚动阻力大。NR和1,4—BR呈现较好的滚动... 详细信息

序言人们希望轮胎具有滚动阻力低和抗湿滑性能高的特点。滚动阻力主要是由于胎面的滞后作用造成。大多数胎面胶含有SBR、NR和BR。标准的冷乳聚SBR(23％苯乙烯)能赋予硫化胶较好的抗湿滑性能,但是滚动阻力大。NR和1,4—BR呈现较好的滚动阻力特性,但抗湿滑性较差。可见,以通用的聚合物不能减小滚动阻力而不损失抗湿滑性能。为了解决这一问题,人们着手研制新的聚合物。微观结构、苯乙烯链段和分子量分布能得以控制的溶聚苯乙烯—丁二烯聚合物已投入生产。此外。

关键词：滚动阻力抗湿滑性能动态性能 SBR 硫化胶胎面胶锡化合物聚丁二烯苯乙烯基滞后作用

Neoadjuvant hepatic arterial infusion chemotherapy for resectable hepatocellular carcinomas

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Hepatoma Research 2018年第5期4卷 1-11页

作者： Rina Tsutsui Hiroaki Nagamatsu Osamu Itano Akihiro Deguchi Tsubasa tsutsumi Mamoru Hiraki Naohisa Mizukami Jun Akiba Department of Digestive and Transplantation Surgery Tokyo Medical University Hachioji Medical CenterTokyo 193-0998Japan Department of Gastroenterology Juntendo University HospitalTokyo 113-8431Japan Department of Hepato-Biliary-Pancreatic and Gastroenterological Surgery International University of Health and Welfare School of MedicineChiba 286-8686Japan Department of Medicine Kagawa Rosai HospitalKagawa 763-0013Japan Department of Medicine Kurume University School of MedicineFukuoka 830-0011Japan Department of Surgery Yame General HospitalFukuoka 834-0034Japan Department of Radiology Yame General HospitalFukuoka 834-0034Japan Department of Pathology Kurume University School of MedicineFukuoka 830-0011Japan

Aim: To evaluate the effect of neoadjuvant hepatic arterial infusion chemotherapy (HAIC) on the survival of patients with resectable hepatocellular carcinoma (HCC). Methods: Between January 2003 and January 2014, 80 patients underwent hepatic resection for HCC. Of these patients, we evaluated 49 patients who met the following inclusion criteria: (1) preserved liver function (Child-Pugh A);(2) resectable HCC (≤ 3 nodules, regardless of the size);and (3) HCC with high-grade malignant potential. Among them, 13 patients underwent neoadjuvant HAIC and curative hepatectomy (treatment group). The remaining 36 patients underwent curative hepatic resection without neoadjuvant therapy (control group). Survival after hepatic resection was compared retrospectively between the groups. Results: During follow-up, 2 (15.4%) patients in the treatment group and 25 (69.4%) patients in the control group developed recurrence. The 1-, 3-, and 5-year disease-free rates (100%, 78.6%, and 78.6%, respectivelyvs. 65.8%, 33.7%, and 26.6%, respectively;P = 0.003) and overall survival rates (100%, 100%, and 100%, respectively vs. 91.7%, 77.8%, and 55.3%, respectively;P = 0.037) were significantly better in the treatment group than in the control group. Conclusion: Neoadjuvant HAIC decreased the risk of recurrence and improved survival in patients with HCC with high malignant potential.

关键词： Hepatocellular carcinoma transcatheter arterial chemoembolization hepatic arterial infusion chemotherapy

“变化”的力量——iSpace北京来福士店

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设计家 2013年第5期 116-117页

作者： Yoshimasa tsutsumi Misae Hiromatsu tsutsumi & Associates

项目位于北京来福士广场．是美国苹果公司授权的产品零售店。建筑本身是极具动态效果的现代建筑．店铺空间被复杂的混凝土结构所包围．包括倾斜的混凝土柱子、三角形玻璃窗等。在这样的环境下．如何凸显苹果品牌“简单的抽象性”的特征... 详细信息

项目位于北京来福士广场．是美国苹果公司授权的产品零售店。建筑本身是极具动态效果的现代建筑．店铺空间被复杂的混凝土结构所包围．包括倾斜的混凝土柱子、三角形玻璃窗等。在这样的环境下．如何凸显苹果品牌“简单的抽象性”的特征成为设计的核心问题。

关键词：北京混凝土结构苹果公司现代建筑动态效果玻璃窗三角形抽象性

NO-1886降低脂负荷新西兰兔血清甘油三酯和游离脂肪酸

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中国药理学通报 2005年第3期21卷 280-283页

作者：张弛肖俊霞席守民张秋菊王宗保 Kusunoki M tsutsumi K 尹卫东南华大学生物化学与分子生物学教研室湖南衡阳421001 南华大学肿瘤研究所湖南衡阳421001 南华大学实验动物学部湖南衡阳421001 Dept of Internal Medicine Faculty of MedicineAichi Medical UniversityNagakute-choAichigunteAichi480-11Japan Research and Development Otsuka Pharmaceutical Factory IncTokushimaJapan

目的观察NO1886(ibrolipim)对脂肪餐后血脂水平的影响。方法将25只♂新西兰兔随机分为5组正常对照组、脂负荷组、脂负荷+NO1886(05g·kg-1)组、脂负荷+NO1886(10g·kg-1)组、脂负荷+NO1886(15g·kg-1)组;分别在给予20%脂肪乳和相应剂量N... 详细信息

目的观察NO1886(ibrolipim)对脂肪餐后血脂水平的影响。方法将25只♂新西兰兔随机分为5组正常对照组、脂负荷组、脂负荷+NO1886(05g·kg-1)组、脂负荷+NO1886(10g·kg-1)组、脂负荷+NO1886(15g·kg-1)组;分别在给予20%脂肪乳和相应剂量NO1886前后第1、2、4、6、8、24h从兔耳缘静脉采血,离心收集血清,测定血清甘油三酯和游离脂肪酸。结果NO1886能有效地降低脂负荷后新西兰兔血清甘油三酯和游离脂肪酸水平,呈剂量依赖性,并能使游离脂肪酸恢复到正常。结论NO1886具有调节脂肪餐后血脂水平的作用。

关键词：甘油三脂游离脂肪酸脂肪耐量实验新西兰兔 NO-1886