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Urological Cancers in Burkina Faso: Epidemiological and Anatomopathological Aspects of 2204 Cases

Open Journal of Urology 2020年第5期10卷 111-122页

作者： Clotaire Alexis Marie Kiemdiba Donega yaméogo Aimé Sostnhène Ouédraogo Adama Ouattara Brahima Kirakoya Nayi Zongo Tiéoule M. Traoré Bienvenu Ky Fasnewendé Aristide Kaboré Department of Urology Yalgado Ouedraogo Teaching Hospital Ouagadougou Burkina Faso Department of Pathology Yalgado Ouedraogo Teaching Hospital Ouagadougou Burkina Faso Department of Urology Sanon Souro Teaching Hospital Bobo Dioulasso Burkina Faso Department of Surgery Yalgado Ouedraogo Teaching Hospital Ouagadougou Burkina Faso Department of Urology Ouahigouya Teaching Hospital Ouahigouya Burkina Faso

Purpose: To study the epidemiological and anatomopathological aspects of urological cancers in Burkina Faso from 1988 to 2018. Patients and Methods: A cross-sectional, retrospective and descriptive study of histologically confirmed cancers that are collected from pathological anatomy laboratory records. The aspects studied were age, sex, location and histological type. Results: A total of 2204 cases of urological cancer were collected. The predominance was male with a sex-ratio of 9.6. The average age was 63.32 years. We found 1602 cases of prostate cancer (72.68%), 361 cancers of the bladder and excretory tract (16.4%), 180 cancers of the kidney (8.16%), 33 testis cancers (1.5%) and 28 penile cancers (1.3%). The predominant histological type of prostate cancer was adenocarcinoma (96.4%) with a Gleason score 7 in 30.4% of cases. Bladder cancer consisted of 50% epidermoid carcinomas. Kidney cancer was mostly nephrotoblastomas with 42.2% of cases. We noted 42.4% of seminomas among testis cancers and 89.3% of epidermoid carcinomas within penile cancers. Conclusion: The incidence of urological cancers is increasing in Burkina Faso. These cancers occur at a relatively advanced age with male predominance. Prostate cancers are at the forefront of these urological cancers. The establishment of a cancer registry would allow better follow up of cancers in our countries.

关键词： Urological Cancers Epidemiology Burkina Faso

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Isolated Rupture of Corpus Spongiosum Associated a Partial Rupture of the Urethra during a False Step of the Coitus: A Case Reported at the University Hospital Sanou Souro

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Open Journal of Radiology 2017年第2期7卷 143-149页

作者： Zakari Nikièma Abdoul Karim Paré Clotaire A. M. K. D. yaméogo Adama Ouattara Ida Aida Tankoano Dominique Bicaba Brahima Kirakoya Timothé Kambou Rabiou Cissé Medical Imaging Unit Souro Sanou University Teaching Hospital Bobo-Dioulasso Burkina Faso Urology Unit Sourosanou United University Hospital Bobo-Dioulasso Burkina Faso Urology Unit Yalgado Ouédraogo United University Hospital Ouagadougou Burkina Faso Medical Imaging Unit Yalgado Ouedraogo University Teaching Hospital Ouagadougou Burkina Faso

Penile fracture is a rare urological emergency. It occurs mainly in young adults during sexual intercourse. In many instances, one of the corpora carvanosus is involved though bilateral injuries with or without corpus spongiosus involvement is not uncommon. However, isolated injury to corpus spongiosus is extremely rare. We report a case of isolated rupture of corpus spongiosum secondary to penile injury during coitus in a 43-year-old man that presented to University Hospital Souro Sanou of Bobo Dioulasso. He presented with history of persistence bleeding per urethra following penile injury during sexual intercourse. The Retrograde urethrography (RUG) showed a partial rupture of urethra, Moore type 3. Complementary penile ultrasound revealed extensive contusion of the urethra with circumferential hematoma and rupture of the distal 1/3 of the corpus spongiosus. He had gentle per urethral catheterization which was left for one month. Penile ultrasound sound done after removal of catheter showed residual injury and narrowing of the urethra.

关键词： Penile Fracture False Steps of Coitus Rupture of Corpus Spongiosum Urethra Injury Ultrasound

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Effects of length alteration of OPE-containing mono- and dinuclear alkynylplatinum(II) terpyridine complexes on photophysical, structural and morphological properties

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Nano Research 2024年第10期17卷 8893-8903页

作者： Jason Koon-Lam Poon Sammual Yu-Lut Leung Eric Ka-Ho Wong Vivian Wing-Wah yam Institute of Molecular Functional Materials State Key Laboratory of Synthetic Chemistry and Department of ChemistryThe University of Hong KongHong Kong 999077China

A series of mononuclear complexes and unsymmetric dinuclear alkynylplatinum(II)terpyridine complexes with oligo(paraphenylene ethynylene)(OPE)-derived backbone with a variation of the lengths of alkoxy chains and OPE backbones was *** morphological properties,packing lattice and gelation behaviors of the mononuclear complexes were systematically studied,and the thermodynamic parameters and packing lattices of the dinuclear complexes were also investigated,providing further insights into the roles of the non-covalent interactions and their delicate balance in constructing sophisticated supramolecular *** and nanotube formation have been observed upon a delicate control of the intermolecular interactions by altering the lengths and structural dimensions of the complexes.

关键词： supramolecular chemistry self-assembled nanostructures platinum(II)complexes metallogel

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Prognosis of Misgav-Ladach Caesarean Sections in an African Environment: Case of the Banfora Regional Hospital in Burkina Faso about 110 Cases

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Open Journal of Obstetrics and Gynecology 2017年第9期7卷 1006-1015页

作者： Ouattara Adama yaméogo Relwendé Barnabé Kaboré Francois Xavier Gueswendé Kiemtoré Sibraogo Kain Dantola Paul Sawadogo Yobi Alexi Dao Yissou Ouedraogo Issa Ouédraogo Charlemagne Marie Ouédraogo Ali Millogo/Traoré Francoise Thieba/Bonané Blandine The University Teaching Hospital of Ouagadougou Ouagadougou Burkina Faso The Regional Hospital of Banfora Banfora Burkina Faso The Regional Hospital of Ouahigouya Ouahigouya Burkina Faso

Objective: To analyze the caesarean section prognosis aspects according to Misgav-Ladach versus classical technique in the regional hospital of Banfora. Materials and Methods: This is about a randomized clinical test of 2 groups carried in the regional hospital in Banfora on a two-month period from 1st October to 30 November 2015. In the first group, 66 patients had benefited from a caesarean section by the Misgav-Ladach technique. In the control group, 44 patients had benefited from a caesarean in the conventional technique. Were included in our sample all patients having benefited from a cesarean in the study site during the study period and who had consented to participate in the study. All patients were followed until the postpartum healing of the surgical wound. All prognostic elements have been compared. The results were analyzed with Epi Info 3.5.1 software and the significance level was set at 5%. Results: The indications for cesarean section were dominated by maternal causes in 70 cases (63.6%). The average duration of the surgical procedure was 27.98 mm for Misgav-Ladach technique versus 28.27 mm for the conventional technique (p = 0.49). The evaluation of blood loss by the change in hemoglobin pre- and post-operative did not find statistically significant differences between the two techniques (p = 0.6). The evaluation of the number of intraoperative suture used, was in favor of the technique of Misgav-Ladach (p = 0.007). The evolutionary trend in the intensity of postoperative pain was in favor of the technique of Misgav-Ladach. The average time of wound healing was 16.33 days for group 1 versus 21, 27 days for group 2 (p = 0.0001). Postoperative morbidity was greater with the conventional technique in comparison to Misgav-Ladach’s (p = 0.046). There was no statistically significant differences in length of hospital stay (p = 0.056). Conclusion: The Misgav-Ladach cesarean section reduces operative risk. The adoption and diffusion of this technique to the

关键词： Cesarean Misgav-Ladach Morbidity Banfora

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Epidemiology of Sexual Behaviour with Risk of Sexually Transmissible Infection (STI) among Students in Africa: The Case of the University of Ouagadougou

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Open Journal of Obstetrics and Gynecology 2016年第4期6卷 219-231页

作者： C. M. R. Ouedraogo F. D. Millogo Traore A. Ouattara A. Ouedraogo X. Kaboré D. P. Kain B. yaméogo E. Komboigo M. Guinko J. Lankoandé Department of Gynecology and Obstetrics The University Teaching Hospital Yalgado Ouedraogo Ouagadougou Burkina Faso

Objective: To study the sexual risk behaviors and their determining role in sexually transmissible infection (STI) and HIV among students of the University of Ouagadougou. Methodology: It was a descriptive and analytical single pass cross-sectional study from June 22 to July 21 2010 at the University of Ouagadougou. A cluster sampling in two stages was adopted to form a population of 762. Data were collected using a standardized written questionnaire completed by individual interview after informed consent. Results: The average age of students was 24.2 ± 2 years old for men and 23.7 ± 2 years old women. Singles represented 95.1% of students. The students were not scholarship grantees in 90.6% of the sample. Knowledge about STIs was average in 60.2% of cases. In total 33.65% of the students admitted to having had multiple sexual partners, 19.57% had sex with prostitutes, 34.62% had unprotected sex, 4% practiced sodomy without condoms and 3.1% of students had sex in group with one partner. In multivariate analysis, male gender was the determining factor associated with multiple sexual partner (OR = 3.30 95% CI = 2.19 to 4.95) and relations with prostitutes with an odds ratio of 16.13 (95 = 6.87% to 37.8%). The female gender was the determining factor associated with not using a condom with odds ratio of 1.5 (95% CI = 1.01 to 2.16). Conclusion: There are many risk behaviors for HIV transmission among students of the University of Ouagadougou. The urgent implementation of specific prevention programs to benefit this population is essential.

关键词： Risks Sexual Behavior Student Ouagadougou

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Determinants of Fruit and Vegetables Intake among Secondary School Pupils in the City of Bobo-Dioulasso (Burkina Faso): A Cross-Sectional Study

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Open Journal of Internal Medicine 2018年第1期8卷 1-9页

作者： Téné Marceline yaméogo Issiaka Sombié Carole Gilberte Kyelem Oumar Guira Djingri Lankoandé Bazoumana Coulibali Mireille Marie Déborah Tapsoba Alassane Ilboudo Aimée Sankaye-Lagom Kissou Abraham Bagbila Apollinaire Sawadogo Macaire Sampawinde Ouédraogo Youssouf Joseph Drabo INSSA Université Nazi Boni Bobo-Dioulasso Burkina Faso CHU Souro Sanon Bobo-Dioulasso Burkina Faso UFR-SDS Université Joseph Ki-Zerbo Ouagadougou Burkina Faso

According to WHO, eating at least five portions of fruit and vegetables a day at an early age is protective against cancers, cardiovascular diseases and diabetes. The purpose of this study was to determine among secondary school pupils in the city of Bobo-Dioulasso, the level of observation of this recommendation and the associated factors. Methods: This was a cross-sectional study conducted from March to April 2016, among secondary school pupils in 1st Form, 4th Form and 7th Form of public and private secondary schools. The diet survey methods were the recalling of the last 24 hours associated with intake frequency questionnaire. An intake of less than one fruit (or a slice of a big fruit) per day and for vegetables, less than one portion of raw or cooked vegetables per day was considered insufficient. Results: A total of 1993 pupils were surveyed. The mean age was 17.5 ± 3.6 years and the sex ratio 0.7;75.4% and 90.0% of pupils had insufficient daily intake of fruit and vegetables respectively. The determinants of this consumption deficiency were: Sex (male, OR = 1.7 (1.3 - 2.2)), secondary school (public, OR = 1.6 (1.3 - 2.0)), class (4th Form, OR = 2.5 (1.5 - 4.2)/7th Form, OR = 3.7 (2.7 - 5.1)), the mother (thin build, OR = 3.2 (2.0 - 5.3)/overweight/obesity, OR = 2.8 (1.6 - 4.7)) and physical inactivity (OR = 1.5 (1.2 - 2.0)). Conclusion: The promotion of a healthy diet among secondary school pupils should take into account the type of school, sex, educational level, physical activity and mothers’ influence.

关键词： Fruit and Vegetables Intake Cardiovascular Prevention Young Subject

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Contribution of Ambulatory Blood Pressure Monitoring to the Management of Arterial Hypertension at Blaise CompaoréUniversity Hospital

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World Journal of Cardiovascular Diseases 2017年第12期7卷 442-450页

作者： Yibar Kambiré Georges Kinda Georges R.C. Milllogo Lassina Konaté Issa Diallo K. Jonas Kologo Jean-Baptiste Tougouma Germain D. Mandi R. Aristide yaméogo Salifou Yaogo Caleb Tindano André K. Samadoulougou Patrice Zabsonré Department of Medicine and Medical Specialties Blaise COMPAORE University Hospital Ouagadougou Burkina Faso Department of Health Sciences University of Ouagadougou Ouagadougou Burkina Faso Cardiology Department Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso Cardiology Department Souro Sanou University Hospital Bobo-Dioulasso Burkina Faso

Background: Hypertension is a major public health concern in Burkina Faso. Its management relies on in-office medical setting blood pressure monitoring which is known to be an imperfect diagnosis tool. Objective: This study aims to assess the contribution of ambulatory blood pressure monitoring in the management of hypertension at Blaise Compaoré University Hospital. Methods: A monocentric descriptive retrospective study was conducted in the cardiology outpatient unit of Blaise Compaoré University Hospital. Patients aged at least 18 years who underwent ambulatory blood pressure monitoring between March 2013 and June 2015 were enrolled. Hypertension was defined as follows: average blood pressure over 24 hours > 130/80 mmHg, or diurnal blood pressure > 135/85 mmHg, or nocturnal blood pressure >120/70 mmHg. Data were analyzed using the SPSS 20.0 software. The threshold for significance was set at 5% for a validity interval at 95%. Chi square test was used for?the statistical analysis. Results: A total of 122 patients were enrolled. The main reasons for ambulatory monitoring were the evaluation of hypertensive therapy (51.6%) and the diagnosis confirmation (39.3%). The results of the ambulatory monitoring found 61.4% of the patients with hypertension and 37.7% with normal blood pressure. A treatment adjustment was made for 36.1% of the patients;an initiation of antihypertensive therapy was undertaken for 24.6%, an abstention from drug therapy was recommended?for 23.8%,?and the pursuit of previous treatment for 13.1% of the patients. Conclusion: Ambulatory blood pressure monitoring should be used more often in order to optimize the management of hypertension in our current practice.

关键词： Hypertension Diagnosis Treatment Ambulatory Monitoring Africa

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Experimental Study and Thermal Modelling of Cocoa Shell Convective Drying in an Indirect Solar Dryer

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Modeling and Numerical Simulation of Material Science 2024年第2期14卷 69-78页

作者： Siaka Touré Adjo Christelle ogo Modibo Sidibé Solar Energy Laboratory FHB University of Cocody Abidjan C&#244te d’Ivoire

The concern of the present work is the convective drying of empty cocoa shells in an indirect solar dryer. Some drying experiments, using one sample, were carried out. During the experiments, the sample is introduced in the drying chamber. Then at steady time intervals, the sample is withdrawn from the drying chamber, for a rapid weighing. After each weighing, the sample is reintroduced in the dryer. At each time interval, the ambient temperature of the drying chamber and its relative humidity γ are measured by a thermo-hygrometer. From the experimental data, a theoretical determination of the moisture evaporated from the product was performed and a good agreement was found between the theoretical and experimental values, confirmed by the value of the RMSE. Those calculations used the constants in the Nusselt number found in literature. Then those constants were evaluated again, to get new values more suitable with the experimental data. The dimensionless numbers of Nusselt, Grashof and Prandtl were calculated. That allowed the calculation of the average value of the Nusselt number. The average convective heat transfer coefficient was determined.

关键词： Shells of Cocoa Pods Indirect Solar Dryer Moisture Evaporated Constants of the Nusselt Number Convective Heat Transfer Coefficient

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NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma

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Cancer Communications 2024年第2期44卷 251-272页

作者： Yue Yao Yi Xu Liang Yu Ting-Mao Xue Zhi-Jie Xiao Pui-Chi Tin Hiu-Ling Fung Hoi-Tang Ma Jing-Ping Yun Judy Wai Ping yam Department of Pathology School of Clinical MedicineLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongP.R.China Department of Endocrinology and Metabolism Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjingP.R.China Department of Hepatopancreatobiliary Surgery Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjingP.R.China State Key Laboratory of Oncology in South China Cancer Center of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Hepatobiliary Surgery II Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdongP.R.China Scientific Research Center The Seventh Affiliated HospitalSun Yat-sen UniversityShenzhenGuangdongP.R.China State Key Laboratory of Liver Research The University of Hong KongHong KongP.R.China Department of Pathology Cancer Center of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China

Background:Small extracellular vesicles(sEVs)mediate intercellular commu-nication that contributes to hepatocellular carcinoma(HCC)progression via multifaceted *** success of cell entry determines the effect of sEV on recipient ***,we aimed to delineate the mechanisms underlying the uptake of sEV in ***:AF,Alexa Fluor;ANOVA,analysis of variance;ATP9A,ATPase Phospholipid Transporting 9A;BCECF-AM,2’,7’-bis-(2-barboxyethyl)-5-(and-6)-carboxyfluorescein,acetoxymethyl ester;BSA,bovine serum albumin;CCMR,Centre for Comparative Medicine Research;CRISPR,clustered regularly interspaced short palindromic repeats;CTL,ctrl;CXCR4,C-X-C Chemokine Receptor Type 4;DAPI,4′,6-diamidino-2-phenylindole;DFS,disease-free survival;DMEM,Dulbecco’s Modified Eagle Medium;DMSO,dimethyl sulfoxide;Dox,doxycycline;EEA1,early endosome antigen 1;EIPA,5-(N-ethyl-N-isopropyl)-amiloride;FBS,fetal bovine serum;FITC,fluorescein isothiocyanate;GAPDH,glyceraldehyde-3-phosphate dehydrogenase;GM130,Golgi matrix protein 130;HCC,hepatocellular carcinoma;HEPES,4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid;HPRT1,hypoxanthine phosphoribosyltransferase 1;H-score,histoscore;IAA,indole-3-acetic acid;KD,knockdown;KO,knockout;mAID,mini-auxin-inducible degron;MTT,3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide;NHE7,Na(+)/H(+)exchanger 7;ns,non-significant;OD,optical density;OS,overall survival;PBS,phosphate-buffered saline;PCR,polymerase chain reaction;pHe,endosomal pH;pHi,intracellular pH;PKH67,Paul Karl Horan 67;Rab21,Ras-associated binding protein 21;RIPA,radioimmunoprecipitation assay;SAM,synergistic activation mediator;SEMs,standard error of the means;sEVs,small extracellular vesicles;sgRNA,single-guide RNA;shRNA,short-hairpin RNA;SLC9,solute carrier gene 9;SLiCE,Seamless Ligation Cloning Extract;TCGA,The Cancer Genome Atlas;TCL,total cell lysates;TGN,trans-Golgi network;TMA,tissue microarray;TMR,tetramethyl rhodamine;TSG101,tumor susceptibility gene *** Yao an

关键词： hepatocellular carcinoma small extracellular vesicles macropinocytosis pH regulation sodium-hydrogen exchanger

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Technical-Economic Performance, Carcass and Meat Quality of COBB500 Broilers Fed Rations Incorporating Mango By-Product Feeds in Ivory Coast (West Africa)

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Open Journal of Animal Sciences 2024年第1期14卷 1-13页

作者： Timbilfou Kiendrébéogo Alidjata Traoré Etienne Sodre Drissa Barry Isidor Ouedraogo Marcelle Grace Koidja Vianney Tarpaga Centre National de la Recherche Scientifique et Technologique Institut de l’Environnement et de Recherches Agricoles Laboratoire de Recherches en Production et Santé Animales (LAREPSA) Bobo-Dioulasso Burkina Faso Centre National de la Recherche Scientifique et Technologique Institut de l’Environnement et de Recherches Agricoles Laboratoire Central d’Horticulture (LCH) Bobo-Dioulasso Burkina Faso Laboratoire d’Etude des Ressources Naturelles et des Sciences de l’Environnement (LERNSE) Ecole Doctorale Sciences Naturelles et Agronomie (ED-SNA) Université Nazi BONI Bobo-Dioulasso Burkina Faso Université Catholique de l’Afrique de l’Ouest (UCAO) Section du Burkina Faso Bobo-Dioulasso Burkina Faso Direction Régionale de l’Agriculture des Ressources Animales et Halieutiques de l’Est Fada Burkina Faso

The study evaluated the growth performance and carcass quality of COBB500 broilers fed two experimental rations incorporating feed and mango fine ED10 for a batch of 83 birds, ED20 (batch of 83 birds) in comparison with a commercial control ration CCD (84 birds). For this purpose, 250 day-old chicks of this breed were purchased in Korhogo and transported to Tengréla in Ivory Coast for rearing. The results show that substituting mango provender ans and mango seed flour for maize resulted in rations with costs per kgMS of 215.35FCFA, 2016.93FCFA and 320FCFA for the ED10, ED20 and CCD rations respectively. The production costs per kg of chicken (FCPkgLW) of the CCD ration were significantly higher than those of the ED10 and ED20 (p 0.05). ADGs were significantly different and decreasing from CCD, ED20 to ED10 (p 0.05). Average weights at 42nd day for ED20 and CCD were homogeneous (p > 0.05) and significantly higher than for ED10 (p 0.05). By day 49th the average weight of ED20 had reached and exceeded that of CCD by day 42nd. PSLW, HCW and CCW were significantly different and decreasing from CCW, ED20 to ED10 (p 0.05). Average hot (HCY) and cooled (CCY) carcass yields of ED20 and CCD rations were comparable (p > 0.05) and significantly higher than those of ED10 ration (p = 0.009) and 0.003). Average drumstick and neck weights were significantly higher and lower for CCD, ED20 and ED10 (p 0.05). For all other parts of the cut, the average weights of the CCD ration were significantly higher (p 0.05) than those of the ED20 and ED10 rations, which were homogeneous (p 0.05). The incorporation of mango provender and mango seed flour in broiler rations offers the prospect of reduced production costs, less competition between man and animals over cereals, and lean meat production tha

关键词： Broiler COOB 500 Chickens Mango Feed Carcass Characteristics Tengrela Ivory Coast

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