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Effectiveness of simulation-based learning regarding management of post-COVID complications in terms of knowledge,clinical decision-making ability,and self-efficacy among nursing students:A quasi-experimental study

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Journal of Acute Disease 2023年第3期12卷 96-101页

作者： Thakur Malvika Eenu Kumar Yogesh Sarin Jyoti nitesh kumawat Shatrughan Pareek Department of Medical Surgical Nursing College of NursingMaharishi Markandeshwar(Deemed to be University)MullanaAmbalaIndia Department of Community Health Nursing College of NursingMaharishi Markandeshwar(Deemed to be University)MullanaAmbalaIndia College of Nursing Maharishi Markandeshwar(Deemed to be University)MullanaAmbalaIndia AIIMS JodhpurRajasthanIndia Indian Railway Health Services BikanerRajasthanIndia

Objective:To assess the effectiveness of simulation-based learning regarding the management of post-COVID complications in terms of knowledge,clinical decision-making ability,and self-efficacy among nursing ***:This was a quasi-experimental study conducted among 1152nd-year nursing *** participants were selected by a simple random sampling *** participants were divided into an experimental(n=56)and a comparison group(n=59)by a random table *** were analyzed using descriptive and inferential statistics with SPSS version ***:There were significant differences in mean post-test knowledge scores(P=0.03)and mean post-test self-efficacy scores(P=0.001)between the experimental and the comparison groups while the difference in mean post-test clinical decision-making ability scores between the two groups was non-significant(P=0.07).A positive correlation was found between knowledge and clinical decision-making ability in pre-test(P=0.03)and in post-test(P<0.001)and a non-significant correlation was found between pre-test knowledge and self-efficacy score(P=0.52)among the experimental ***:Simulation-based learning regarding the management of post-COVID complications is effective among nursing *** labs should be established in health care settings where simulation training can be provided for updating the knowledge,clinical decision-making ability,and self-efficacy of nursing personnel during program installment and continuous nursing education.

关键词： Simulation Knowledge Clinical decision making ability Self-efficacy Post-COVID complications

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Anneal-free ultra-low loss silicon nitride integrated photonics

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Light(Science & Applications) 2024年第8期13卷 1565-1577页

作者： Debapam Bose Mark W.Harrington Andrei Isichenko Kaikai Liu Jiawei Wang nitesh Chauhan Zachary L.Newman Daniel J.Blumenthal Department of Electrical and Computer Engineering University of California Santa BarbaraSanta BarbaraCA 93106USA Octave Photonics LouisvilleCO 80027USA

Heterogeneous and monolithic integration of the versatile low-loss silicon nitride platform with low-temperature materials such as silicon electronics and photonics,III–V compound semiconductors,lithium niobate,organics,and glasses has been inhibited by the need for high-temperature annealing as well as the need for different process flows for thin and thick *** techniques are needed to maintain the state-of-the-art losses,nonlinear properties,and CMOS-compatible processes while enabling this next generation of 3D silicon nitride *** report a significant advance in silicon nitride integrated photonics,demonstrating the lowest losses to date for an anneal-free process at a maximum temperature 250℃,with the same deuterated silane based fabrication flow,for nitride and oxide,for an order of magnitude range in nitride thickness without requiring stress mitigation or *** report record low anneal-free losses for both nitride core and oxide cladding,enabling 1.77 dBm^(-1) loss and 14.9 million Q for 80 nm nitride core waveguides,more than half an order magnitude lower loss than previously reported sub 300℃ *** 800 nm-thick nitride,we achieve as good as 8.66 dBm^(-1) loss and 4.03 million Q,the highest reported Q for a low temperature processed resonator with equivalent device area,with a median of loss and Q of 13.9 dBm^(-1) and 2.59 million each *** demonstrate laser stabilization with over 4 orders of magnitude frequency noise reduction using a thin nitride reference cavity,and using a thick nitride micro-resonator we demonstrate OPO,over two octave supercontinuum generation,and four-wave mixing and parametric gain with the lowest reported optical parametric oscillation threshold per unit resonator *** results represent a significant step towards a uniform ultra-low loss silicon nitride homogeneous and heterogeneous platform for both thin and thick waveguides capable of linear and nonlinear photonic circuits and

关键词： resonator thick free

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Powder mixed electrochemical discharge process for micro machining of C103 niobium alloy

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Defence Technology（防务技术） 2023年第8期26卷 84-101页

作者： Niladri Mandal nitesh Kumar Alok Kumar Das Defence Research&Development Laboratory(DRDL)-DRDO HyderabadIndia Department of Mechanical Engineering Indian Institute of Technology(ISM)DhanbadIndia

This work demonstrates the viability of the powder-mixed micro-electrochemical discharge machining(PMECDM) process to fabricate micro-holes on C103 niobium-based alloy for high temperature *** processes are involved simultaneously *** erosion,chemical etching,and abrasive grinding for removal of material while the classical electrochemical discharge machining process involves double actions *** erosion,and chemical *** powder-mixed electrolyte process resulted in rapid material removal along with a better surface finish as compared to the classical microelectrochemical discharge machining(MECDM).Further,the results are optimized through a multiobjective optimization approach and study of the surface topography of the hole wall surface obtained at optimized *** the selected range of experimental parameters,PMECDM shows a higher material removal rate(MRR) and lower surface roughness(R_(a))(MRR:2.8 mg/min and R_(a) of 0.61 μm) as compared to the MECDM process(MRR:2.01 mg/min and corresponding Raof 1.11 μm).A detailed analysis of the results is presented in this paper.

关键词： Micro-electrochemical discharge machining C103 niobium alloy Surface integrity Material removal rate Hybrid powder mixed ECDM

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Cumulant-based correlated probabilistic load flowconsidering photovoltaic generation and electric vehiclecharging demand

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Frontiers in Energy 2017年第2期11卷 184-196页

作者： nitesh Ganesh BHAT B. Rajanarayan PRUSTY Debashisha JENA Department of Electrical and Electronics Engineering National Instituteof Technology Karnataka Surathkal Mangalore 575025 India

This paper applies a cumulant-based analytical method for probabilistic load flow (PLF) assessment in transmission and distribution systems. The uncertainties pertaining to photovoltaic generations and aggregate bus load powers are probabilistically modeled in the case of transmission systems. In the case of distribution systems, the uncertainties pertaining to plug-in hybrid electric vehicle and battery electric vehicle charging demands in residential community as well as charging stations are probabilistically modeled. The probability distributions of the result variables (bus voltages and branch power flows) pertaining to these inputs are accurately established. The multiple input correlation cases are incorporated. Simultaneously, the performance of the proposed method is demonstrated on a modified Ward-Hale 6-bus system and an IEEE 14-bus transmission system as well as on a modified IEEE 69-bus radial and an IEEE 33-bus mesh distribution system. The results of the proposed method are compared with that of Monte-Carlo simulation.

关键词： battery electric vehicle extended cumulant method photovoltaic generation plug-in hybrid electric vehicle probabilistic load flow

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Nitrogen-doped biochars as adsorbents for mitigation of heavy metals and organics from water:a review

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Biochar 2022年第1期4卷 906-935页

作者： nitesh Kasera Praveen Kolar Steven G.Hall Department of Biological and Agricultural Engineering North Carolina State UniversityRaleighNCUSA

Mitigation of toxic contaminants from wastewater is crucial to the safety and sustainability of the aquatic ecosystem and human *** is a pressing need to find economical and efficient technologies for municipal,agricultural,aquacultural,and industrial wastewater ***-doped biochar,which is synthesized from waste biomass,is shown to exhibit good adsorptive performance towards harmful aqueous contaminants,including heavy metals and organic ***-porating nitrogen into the biochar matrix changes the overall electronic structure of biochar,which favors the interaction of N-doped biochar with *** this review,we start the discussion with the preparation techniques and raw materials used for the production of N-doped biochar,along with its structural ***,the adsorption of heavy metals and organic pollutants on N-doped biochars is systematically *** adsorption mechanisms of contaminant removal by N-doped biochar are also clearly ***,mathematical analyses of adsorption,crucial to the quantification of adsorption,process design,and understanding of the mechanics of the process,are ***,the influence of environmental parameters on the adsorption process and the reusability of N-doped biochars are critically ***,future research trends for the design and development of application-specific preparation of N-doped biochars for wastewater treatment are suggested.

关键词： N-doped Nitrogen-enriched Adsorption Wastewater Mechanism

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A novel oil-in-water drilling mud formulated with extracts from Indian mango seed oil

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Petroleum Science 2020年第1期17卷 196-210页

作者： Saket Kumar Aarti Thakur nitesh Kumar Maen M.Husein Department of Chemical and Petroleum Engineering The University of CalgaryCalgaryAB T2N 1N4Canada Emerson Innovation Center PuneMaharashtraIndia MDNK Oil and Gas Consultants MumbaiMaharashtraIndia

Drilling muds with less environmental impact are highly desired over conventional diesel-based mud systems,especially in light of the emerging strict environmental *** this article,a novel oil-in-water(O/W)emulsion drilling fluid formulated with a methyl ester extracted from Indian mango seed oil was *** effect of the weight percent of different constituents of the emulsion/suspension including the oil phase,bentonite,and polyanionic cellulose polymer on the rheology and the fluid loss was *** methyl ester oil phase/mud system displayed superior physical,chemical,rheological and filtration properties relative to the diesel and the mango seed ***-toxicity of the methyl ester and diesel(O/W)emulsion mud systems was assessed using the acute lethal concentration *** Indian mango methyl ester(O/W)emulsion mud displayed much less impact on fish *** characteristics collected from the flow model at 85°C suggested excellent shear thinning behavior of the Indian mango methyl ester(IMME)(O/W)emulsion ***,the IMME(O/W)emulsion displayed strong pseudoplastic behavior,an attractive feature in a drilling mud,with increasing clay content and polymer *** methyl ester mud was thermally stable over a wide range of the constituent ***,a particle size analysis revealed that engineered drilling muds targeting suspension of particles with certain size range can be formulated by changing the volume fraction of the methyl ester in the mud system.

关键词： Indian mango seed oil Fluid loss Emulsion drilling mud Shear thinning Pseudoplastic fluid

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Relief from vascular occlusion using photothermal ablation of tlhrombus with a multimodal perspective

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Nano Research 2016年第8期9卷 2327-2337页

作者： nitesh Singh Anand Varma Ashish Verma Babu N. Maurya Debabrata Dash Department of Biochemistry Institute of Medical Sciences Banaras Hindu University Varanasi 221005 India Department of Radiodiagnosis and Imaging Institute of Medical Sciences Banaras Hindu University Varanasi 221005 India

Fibrinolytic therapy for arterial or venous thrombotic disorders involves the systemic administration of thrombolytics such as streptokinase, which is associated with serious bleeding complications. With this study, we provide a proof-of-concept of photothermal thrombus ablation with gold nanorods exposed to near-infrared irradiation, both in vitro using materials generated from purified fibrinogen or plasma and in vivo in murine blood vessels. This is the first report of the application of photothermal therapy as an anti-thrombotic measure. Remarkably, the addition of streptokinase had a multimodal additive effect with regard to acceleration of photothermal lysis of thrombi even at a dose significantly below the therapeutic concentration, thus minimizing the life- threatening side effects and adverse complications. This combinatorial approach exhibits great promise for lysing pathological clots while effectively overcoming the drawbacks of existing therapies.

关键词： platelet fibrin near-infrared laser photothermal therapy thrombolysis streptokinase

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Evolution and bathymetry of glacial lake at the lowest elevation in Nepal Himalaya

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Journal of Mountain Science 2023年第1期20卷 141-144页

作者： Shusila KANDEL nitesh KHADKA Dhurba TIWARI Dibas SHRESTHA Kedar RIJAL Central Department of Environmental Sciences Tribhuvan UniversityKathmandu44163Nepal Key Laboratory of Mountain Hazards and Earth Surface Process Institute of Mountain Hazards and EnvironmentChinese Academy of SciencesChengdu610041China University of Chinese Academy of Sciences Beijing100049China Department of Geology Tri-Chandra Multiple CampusTribhuvan UniversityKathmandu44600Nepal Central Department of Hydrology and Meteorology Tribhuvan UniversityKathmandu44163Nepal

One of the prominent impacts of climate change induced glacier retreat in the Himalayas is the formation and expansion of glacial lakes. The newly formed glacial lakes are mostly located in higher altitudinal regions(4200-5800 m) of Himalaya,however, a new glacial lake(Kapuche, 28.446° N and 84.116° E) have been reported to be emerged in the relatively low elevation area of ~2450 m above sea level(masl) in the Nepal Himalaya. This short communication presents the remote sensing-based evolution and field-based bathymetry of Kapuche lake, and further discusses its formation process and lake type for being a glacial lake at the lowest elevation in Nepal Himalaya.

关键词： Glacial lake Evolution Avalanche Bathymetry

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An update–tissue engineered nerve grafts for the repair of peripheral nerve injuries

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Neural Regeneration Research 2018年第5期13卷 764-774页

作者： nitesh P.Patel Kristopher A.Lyon Jason H.Huang Texas A&M College of Medicine Temple TX USA Department of Neurosurgery Baylor Scott & White Healthcare Temple TX USA

Peripheral nerve injuries（PNI） are caused by a range of etiologies and result in a broad spectrum of disability. While nerve autografts are the current gold standard for the reconstruction of extensive nerve damage, the limited supply of autologous nerve and complications associated with harvesting nerve from a second surgical site has driven groups from multiple disciplines, including biomedical engineering, neurosurgery, plastic surgery, and orthopedic surgery, to develop a suitable or superior alternative to autografting. Over the last couple of decades, various types of scaffolds, such as acellular nerve grafts（ANGs）, nerve guidance conduits, and non-nervous tissues, have been filled with Schwann cells, stem cells, and/or neurotrophic factors to develop tissue engineered nerve grafts（TENGs）. Although these have shown promising effects on peripheral nerve regeneration in experimental models, the autograft has remained the gold standard for large nerve gaps. This review provides a discussion of recent advances in the development of TENGs and their efficacy in experimental models. Specifically, TENGs have been enhanced via incorporation of genetically engineered cells, methods to improve stem cell survival and differentiation, optimized delivery of neurotrophic factors via drug delivery systems（DDS）, co-administration of platelet-rich plasma（PRP）, and pretreatment with chondroitinase ABC（Ch-ABC）. Other notable advancements include conduits that have been bioengineered to mimic native nerve structure via cell-derived extracellular matrix（ECM） deposition, and the development of transplantable living nervous tissue constructs from rat and human dorsal root ganglia（DRG） neurons. Grafts composed of non-nervous tissues, such as vein, artery, and muscle, will be briefly discussed.

关键词： peripheral nerve injury peripheral nerve repair tissue engineered nerve graft nerve conduit stem cells Schwann cells dorsal root ganglia neurons axon stretch-growth autologous tissue graft

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IGMAP： An Interactive Mapping and Clustering Platform for Plants

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Molecular Plant 2015年第5期8卷 818-821页

作者： Piyush Priya nitesh Bandhiwal Gopal Misra Subhashish Mondal Gitanjali Yadav Computational Biology Laboratory National Institute of Plant Genome Research Aruna Asaf Ali Marg New Delhi India

Next-generation sequencing （NGS） technologies have resulted in a massive surge of high-throughput genomic data, particu- larly for the plant kingdom, boosting the development of methods for gene family discovery and identification of clus- tering patterns at genomic scales. Plants are well known for the occurrence of both genic and chromosoma~ duplications that have resulted in the widespread existence of gene families in this kingdom, apart from being associated with subsequent evolutionary divergence via sub-functionalization or neo- functionalization （Flagel and Wendel, 2009）. These divergent mechanisms eventually lead to the formation of gene clusters, which in turn, have been shown to confer selective advantages to the genome including co-inheritance and co- regulation （Fischbach et ai., 2008）. Although gene clusters have been conventionally understood to be the genetic building blocks of prokaryotic genomes, comparative genomic studies have revealed the presence of functionally related genes that are clustered in lower nematodes, fungi, and several higher eukaryotes （Zorio et al., 1994; Blumenthal, 1998; Lee and Sonnhammer, 2003; Hurst et al., 2004; Thomas, 2006）. However, very few data are available on the modularity or clustered linkage of genes in plants, despite the widespread occurrence of duplication events in the kingdom. In this regard, recent reports of biosynthetic modules and clustered organization of genes spotted in several major classes of plant-derived secondary metabolites arising through neo-functionalization and relocation of duplicated or existing genes, have offered an exciting niche （Osbourn, 2010）. The presently available approaches for the identification and analysis of plant gene clusters include map-based cloning, for- ward and reverse genetics, and genome mining. As the wealth of plant genome sequence data continues to increase exponen- tially, newer methods are going to be required to carry out genome mining in a rational and useful

关键词： IGMAP Mapping Platform

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